Ruth Flümann^1*, Julia Hansen, MS^2*, Benedikt Pelzer, MD^3*, Ilmars Kisis^4*, Tim Lohmann^5*, Thorsten Persigehl, MD^4*, Nima Abedpour, PhD^6*, Martin Peifer, PhD^6*, Reinhard Buettner^7*, Bastian von Tresckow, MD⁸, Ron Jachimowicz^2*, Hans Christian Reinhardt, MD⁹ and Gero Knittel, PhD^9*

¹University Hospital of Cologne, Cologne, DC, Germany
²Max Planck Institute for Biology of Ageing, Cologne, Germany
³Weill Cornell Medicine, New York
⁴University of Cologne, Cologne, Germany
⁵University Hospital of Cologne, Cologne, Germany
⁶Department of Translational Genomics and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
⁷University of Cologne, Institute of Pathology, Cologne, Germany
⁸Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⁹Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany

Kostiantyn Dreval^1,2*, Laura K Hilton, PhD^3*, Krysta M. Coyle, PhD², Jasper Wong^3*, Merrill Boyle^3*, Brett Collinge^3*, Manuela Cruz^2*, Barbara Meissner^3*, Christopher K Rushton^2*, Marco A. Marra¹, David W. Scott, PhD, MD, FRACP, FRCPA³, Christian Steidl^3* and Ryan D. Morin^1,4

¹Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
²Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada
³Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
⁴Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada

David M. Kurtz, MD, PhD¹, Gregory J. Hogan, PhD^2*, Andre Schultz, PhD^2*, Katerina Kopeckova, MD, PhD^3*, Christian Kuffer^4*, Derek Blair, PhD^4*, Steve Wagner, PhD^4*, Sandra Close, PhD^2*, Maximilian Diehn, MD, PhD^5*, Jacob J. Chabon, PhD^2*, Ash A. Alizadeh, MD, PhD⁶ and Jason Westin, MD⁷

¹Stanford University, Palo Alto, CA
²Foresight Diagnostics, Aurora, CO
³Department of Oncology of the 2nd Faculty of Medicine of Charles University and University Hospital in Motol, Prague, Czech Republic
⁴MorphoSys AG, Planegg, Germany
⁵Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA
⁶Divisions of Oncology and Hematology, Department of Medicine, Stanford University School of Medicine, San Mateo, CA
⁷The University of Texas MD Anderson Cancer Center, Houston, TX

Jean L. Koff, MD, MSc¹, Rachel Kositsky, BS^2*, David L. Jaye, MD³, Michael C. Churnetski^4*, Katelin Baird, BS^5*, Colin B. O'Leary, MA^6*, Christopher R. Flowers, MD^7,8, Sirpa Leppa, MD, PhD⁹, Marja-Liisa Karjalainen-Lindsberg, MD, PhD^10*, Shaoying Li^11*, Jie Xu, MD^12*, Mette Ø Pedersen, MD PhD^13*, Anne Ortved Gang, MD PhD^13*, Kikkeri N Naresh, MD, MBBS¹⁴, Rebecca J Leeman-Neill, MD, PhD¹⁵, Kwok Him Rex Au Yeung, FRCPath¹⁶, Hina Naushad Qureishi^17*, Javeed Iqbal, Ph.D.^18*, Jennifer R Chapman-Fredricks, MD^19*, Chad M. McCall, MD, PhD^2*, Michael Crump²⁰, Amy Chadburn, MD²¹, Erin C. Mulvey, MD^22*, Izidore S. Lossos, MD²³, Sandra L. Ondrejka, DO²⁴, Eric D. Hsi, MD²⁵, Abner Louissaint Jr., MD, PhD²⁶, Haley Martin^26*, Eric Tse, MBBS, PhD, FRCP, FRCPath²⁷, Cassandra Love², Tushar Dave, MS^2*, Clay Parker^28*, Choon Kiat Ong, PhD²⁹, Andrew G Evans, MD, PhD³⁰, Amir Behdad, MD^31*, Lixin Yang, PhD^32*, Nishitha Reddy, MD³³, Mary Ann Arildsen, MD, PHD^33*, Ridas Juskevicius^34*, Jiong Yan^35*, Magdalena Czader, MD, PhD³⁶, Andrew M. Evens, DO, MBA, MMSc³⁷, Dina Sameh Soliman, MD, PhD, MBBS, MSc³⁸, Yuri Fedoriw, MD^39*, Sandeep S. Dave, MD, MS⁴⁰ and Jonathon B. Cohen, MD, MS⁴¹

¹Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA
²Duke University Medical Center, Durham, NC
³Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Dunwoody, GA
⁴Winship Cancer Institute, Emory University Medical Center, Atlanta, GA
⁵Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA
⁶Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
⁷The Winship Cancer Institute of Emory University, Atlanta, GA
⁸Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
⁹Department of Oncology, Helsinki University Central Hosp., Helsinki, Finland
¹⁰Helsinki University Hospital, Helsinki, Finland
¹¹Department of Hematopathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
¹²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
¹³Copenhagen University Hospital, Herlev, Denmark
¹⁴Department of Pathology, University of Washington, Seattle, WA
¹⁵Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY
¹⁶Department of Pathology, Queen Mary Hospital, Pokfulam, HK Island, Hong Kong
¹⁷University of Nebraska, Omaha
¹⁸Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
¹⁹University of Miami Miller School of Medicine, Miami, FL
²⁰Princess Margaret Hospital, Toronto, ON, Canada
²¹Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
²²Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY
²³Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL
²⁴Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH
²⁵Wake Forest Baptist Medical Center, Winston Salem, NC
²⁶Massachusetts General Hospital, Boston, MA
²⁷Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong
²⁸Data Driven Bioscience, Durham, NC
²⁹Lymphoma Genomic Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore
³⁰University of Rochester Medical Center, Rochester, NY
³¹Northwestern University Feinberg School of Medicine, Chicago, IL
³²Department of Pathology, City of Hope National Medical Center, Duarte, CA
³³Vanderbilt University Medical Center, Nashville, TN
³⁴Vanderbilt University Medical Center, Nashville
³⁵University of Toronto, Toronto, ON, Canada
³⁶Indiana University School of Medicine, Indianapolis, IN
³⁷Rutgers Cancer Institute of New Jersey, Warren, NJ
³⁸Department of Laboratory Medicine and Pathology, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar
³⁹Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁴⁰Duke Cancer Institute, Duke University, Durham, NC
⁴¹Department of Hematology and Medical Oncology, Emory University, Atlanta, GA

Matthew M Klairmont, MD¹, Catherine S. Diefenbach, MD² and Christopher Y. Park, MD, PhD¹

¹Pathology, New York University School of Medicine, New York, NY
²New York University School of Medicine, NYU Cancer Institute, New York, NY

Reiji Fukano, MD, PhD^1*, Yuka Iijima-Yamashita, PhD^2*, Hideto Iwafuchi, MD, PhD^3*, Atsuko Nakazawa, MD, PhD^4*, Akiko Moriya Saito, MD, PhD^2*, Tetsuya Takimoto, MD, PhD^5*, Masahiro Sekimizu, MD, PhD^6*, Yutaka Suehiro, MD, PhD^7*, Shunji Hasegawa, MD, PhD^8*, Tetsuya Mori, MD, PhD^9* and Keizo Horibe, MD, PhD^2,6*

¹Department of Pediatrics, Yamaguchi University Graduate Scool of Medicine, Ube, Japan
²Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan
³Department of Pathology, Shizuoka Children's Hospital, Shizuoka, Shizuoka, Japan
⁴Department of Clinical Research, Saitama Children's Medical Center, Saitama, Japan
⁵Department of Childhood Cancer Data Management, National Center for Child Health and Development, Tokyo, Japan
⁶Department of Pediatrics, National Hospital Organization Nagoya Medical Center, Nagoya, Japan
⁷Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Ube, Japan
⁸Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Japan
⁹Department of Pediatrics, St. Marianna University School of Medicine Hospital, Kanagawa, Japan

Luciano Cascione^1,2*, Afua Adjeiwaa Mensah^1*, Alberto Arribas, PhD^1,2*, Davide Rossi, MD, PhD^1,3, Emanuele Zucca, MD^1,4, Giorgio Inghirami, MD^5*, Anne J. Novak, PhD⁶ and Francesco Bertoni, MD^1,3

¹Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland
²SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland
³Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
⁴Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
⁵Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
⁶Division of Hematology, Mayo Clinic, Rochester, MN

Cristina Jiménez, PhD^1*, María García-Álvarez, PhD^2*, Miguel Alcoceba, PhD^2*, Alejandro Medina, PhD^2*, Elham Askari, MD^3*, Veronica Gonzalez-Calle^2*, Maria Casanova, MD^4*, Fernando Escalante Barrigón, MD^5*, M Eugenia Sarasquete, PhD^2*, Marcos González Díaz, MD, PhD^2*, María Carmen Chillón Santos, PhD^2* and Ramon Garcia-Sanz²

¹Department of Hematology, University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Center-IBMCC (USAL-CSIC), Spain, Salamanca, Salamanca, Spain
²Department of Hematology, University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Center-IBMCC (USAL-CSIC), Spain, Salamanca, Spain
³Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
⁴Hospital Costa del Sol Marbella, Marbella, Spain
⁵Complejo Asistencial Universitario de León, León, Spain

Vivian Changying Jiang, PhD¹, Fangfang Yan, MS^2*, Alexa A Jordan, BS^1*, Yuxuan Che^3*, Yang Liu, PhD^1*, Qingsong Cai, PhD^1*, Yijing Li, MS^1*, Joseph McIntosh, BS^1*, Zhihong Chen^1*, Jovanny Vargas, BS^4*, Yixin Yao, PhD³, Heng-Huan Lee, PhD^1*, Jingling Jin, PhD^3*, Wei Wang, PhD^1*, Lei Nie, MD^1*, Zhongming Zhao, PhD^2*, Lukas M Simon, PhD^5* and Michael L. Wang, MD^1,6

¹Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX
³Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
⁴Department of Lymphoma and Myeloma, M.D. Anderson cancer center, Houston, TX
⁵Therapeutic Innovation Center, Baylor College of Medicine, Houston
⁶Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX

Alejandro Martín-Muñoz^1*, María Poza, MD^2*, Gloria Figaredo, MD^3*, Sara Dorado^1,4*, Yanira Ruiz-Heredia^1,5*, Margarita Rodriguez^1,5*, Laura Rufian^1,5*, Antonia Rodriguez Izquierdo, MD^2*, Laura Parrilla-Navamuel^3*, Chongwu Wang^6*, Paula Toledo^4*, Carlos Grande Garcia^7*, Tycho Baumann^2*, Maria Calbacho, MD^2*, Inmaculada Rapado^5*, Miguel Gallardo, PhD^5*, Miguel Canales, MD, PhD⁷, Pilar Sarandeses^8*, Manuela Mollejo^3*, Luis Felipe Casado Montero, MD⁹, Rosa Ayala^5*, Joaquín Martínez-López, MD, PhD^5*, Santiago Barrio, PhD^1,10* and Ana Jimenez-Ubieto, MD, PhD^2*

¹Altum sequencing Co., Madrid, Spain
²Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
³Hematology Department, Hospital General Universitario de Toledo, Toledo, Spain
⁴Computer Science and Engineering Department, Carlos III University, Madrid, Spain
⁵Haematological Malignancies Clinical Research Unit, Hospital 12 de Octubre Universidad Complutense, CNIO, CIBERONC, Madrid, Spain
⁶Hosea Precision Medical Technology Co., Ltd., Weihai, Shangdong, China
⁷Clínica Universitaria de Navarra, Madrid, Spain
⁸Pathology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
⁹Hospital General Universitario de Toledo, Toledo, Spain
¹⁰H12O-CNIO Hematological Malignancies Group, Clinical Research Unit. CNIO, Madrid, Spain

Shirley S. Mo, MD^1*, Huimin Geng, PhD², Miguel Cerejo, DO^1*, Kwun Wah Wen, MD, PhD³, David A. Solomon, M.D., Ph.D.^3* and James L. Rubenstein, MD, PhD⁴

¹Department of Medicine, University of California, San Francisco, San Francisco, CA
²Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA
³UCSF Pathology, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
⁴UCSF Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA

Mouhamad Khouja, MSc^1*, Elisa Genuardi^2*, Simone Ferrero, MD^2,3, Beatrice Alessandria^2*, Onno Verhagen^4*, Christa Homburg^4*, Vincent H.J. van der Velden, PhD^5*, Paula Gameiro^6*, Ramon Garcia-Sanz⁷, Alejandro Medina, MD^8*, Eva Fronkova, PhD, MD^9*, Monika Brüggemann, MD^1*, Martin Dreyling, MD¹⁰, Eva Hoster^11*, Anton Langerak, PhD^12*, Nikos Darzentas, PhD^1*, Karol Pal, PhD^13*, Peter James Stewart, PhD^14*, David Gonzalez, PhD^14* and Christiane Pott^1*

¹Clinic for Internal Medicine II - Haematology, Oncology, University Clinic Schleswig-Holstein, Kiel, Germany
²Department of Molecular Biotechnologies and Health Sciences, Division of Hematology, University of Torino, Torino, Italy
³Division of Hematology , AOU Città della Salute e della Scienza di Torino, Torino, Italy
⁴Department of Immunocytology, Sanquin Diagnostic Services, Amsterdam, NLD
⁵Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands
⁶Molecular Biology, Instituto Português de Oncologia, Lisboa, Portugal
⁷Hospital Universitario de Salamanca Hematología. Instituto de investigación biomédica de Salamanca (IBSAL), Salamanca, Spain
⁸Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
⁹CLIP - Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, CZE
¹⁰Department of Internal Medicine III, LMU University Hospital, Munich, Germany
¹¹Institute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany
¹²Department of Immunology, Laboratory Medical Immunology, Erasmus MC, Rotterdam, Netherlands
¹³Department of Molecular Medicine, CEITEC MU - Central European Institute of Technology, Masaryk University, Brno, Czech Republic
¹⁴Precision Medicine Centre of Excellence, Queen's University, Belfast, Belfast, United Kingdom

Jiaoyan Lyu^1*, Xiaopeng Ma^1*, Ruiqi Huang^2*, Liyun Zhao^2*, Yiling Yu^2*, Oscar Puig^3*, Yang Liu^2* and James Hilger^4*

¹BeiGene (Beijing) Co., Ltd., Beijing, China
²BeiGene (Shanghai) Co., Ltd., Shanghai, China
³BeiGene USA, Inc., Ridgefield, NJ
⁴BeiGene USA, Inc., San Mateo, CA

Steven Wang^1,2*, Esther E.E. Drees^2,3*, Cristina Gómez-Martín, PhD^2,3*, Vera de Jonge^1*, Monique van Eijndhoven, Eng^3*, Nils Groenewegen, Eng^3,4*, Sandra Veldt-Verkuijlen, Eng^3*, Marcel Nijland, MD, PhD^5*, Marjolein W.M. Van Der Poel⁶, Yorick Sandberg, MD^7*, Rozemarijn van Rijn^8*, Pim Mutsaers, MD^9*, Vibeke K.J. Vergote^10*, Marie José Kersten, MD, PhD¹¹, Yavuz M. Bilgin, MD PhD^12*, Wendy B.C. Stevens, MD^13*, Marc Durian, MD^14*, Tjeerd J.F. Snijders, MD PhD^15*, Daphne de Jong, MD, PhD^3*, Josée M. Zijlstra, MD PhD¹, Martine E.D. Chamuleau, MD, PhD^1,2 and Dirk Michiel Pegtel, PhD^2,3*

¹Department of Hematology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
⁴Exbiome B.V., Amsterdam, Netherlands
⁵University Medical Center Groningen, Groningen, Netherlands
⁶Department of Hematology, Maastricht University Medical Center, Maastricht, Netherlands
⁷Department of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands
⁸Medical Center Leeuwarden, Leeuwarden, Netherlands
⁹Department of Hematology, Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands
¹⁰Department of Hematology, University Hospitals Leuven, Leuven, Belgium
¹¹Department of Hematology, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands
¹²Department of Internal Medicine, Admiraal de Ruijter Hospital, Goes, Netherlands
¹³Department of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
¹⁴Department of Hematology, St Elisabeth Hospital, Tilburg, Netherlands
¹⁵Medisch Spectrum Twente, Enschede, Netherlands

Alison Rutz^*, Kennedee Weber^*, Shelby Lund, BS^*, Jinda Guidinger, BS^*, Aidan Forberg^* and Keenan T. Hartert, PhD

College of Science Engineering and Technology, Minnesota State University, Mankato, Mankato, MN

Yuqin Song, MD¹, Miaomiao Li^2*, Lan Mi^2*, Chunyang Wang^3*, Xiaojuan Wang^3*, Jianhua Zhu^3*, Fei Qi^2*, Hui Yu^2*, Yingying Ye^2*, Dedao Wang^2*, Jiaowu Cao^2*, Dingyao Hu^2*, Quanyu Yang^3*, Dandan Zhao^3*, Tonghui Ma^3* and Jun Zhu, PhD²

¹Department of Lymphoma, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, BEIJING, China
²Department of Lymphoma, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China
³Genetron Health (Beijing) Technology, Co. Ltd., Beijing, China

Ymke van der Pol^1,2*, Steven Wang^2,3*, Norbert Moldovan^1,2*, Vera de Jonge^2,3*, Esther E.E. Drees^1,2*, Margaretha Roemer^1,2*, Bauke Ylstra^2,4*, Marcel Nijland, MD, PhD^5*, Marjolein W.M. Van Der Poel⁶, Koen de Heer^7*, Clara Klerk^8*, Rozemarijn van Rijn^9*, Rob Fijnheer^10*, Vibeke K.J. Vergote^11*, Aart Beeker¹², Laurens Nieuwenhuizen^13*, Rogier Mous^14*, Joost S.P. Vermaat, MD, PhD¹⁵, D. Michiel Pegtel^1,2*, Martine E.D. Chamuleau, MD, PhD^2,3 and Florent Mouliere^1,2*

¹Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Hematology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
⁴Amsterdam UMC, Vrije Universiteit Amsterdam, department of Pathology, Cancer Center Amsterdam, Amsterdam, Netherlands
⁵University Medical Center Groningen, Groningen, Netherlands
⁶Maastricht University Medical Center, Maastricht, Netherlands
⁷Department of Internal Medicine, Flevoziekenhuis, Almere, Netherlands
⁸Dijklanderziekenhuis, Hoorn, Netherlands
⁹Medical Center Leeuwarden, Leeuwarden, Netherlands
¹⁰Meander Medical Center, Department of Internal Medicine, Amersfoort, Netherlands
¹¹Department of Hematology, University Hospitals Leuven, Leuven, Belgium
¹²Spaarne Ziekenhuis, Hoofddorp, Netherlands
¹³Máxima Medical Center, Veldhoven, Netherlands
¹⁴Department of Hematology, Universitair Medisch Centrum Utrecht, Utrecht, NH, Netherlands
¹⁵Department of Hematology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

Samantha A Hershenfeld, BSc¹, Victoria Shelton, MSc^1*, Mehran Bakhtiari, MSc^1*, Lourdes Calvente, MD^1*, Katherine Lajkosz, MSc^2*, Keren Isaev, MSc^1*, Anjali Silva, PhD, MSc, BSc^1*, Ting Liu, PhD^1*, Marianne Brodtkorb, MD, PhD^3*, Francesco Annibale d'Amore, MD, DMSc⁴, Maja Ludvigsen, PhD^4,5*, Charlotte Madsen, MD, PhD^4*, Stephen Hamilton-Dutoit, MD^6*, Maher Gandhi, MBChB PhD⁷, Joshua W.D. Tobin, MD^8*, Tara Baetz, MD^9*, David LeBrun, MD¹⁰, Nathalie A. Johnson, MD, PhD,¹¹, Andrew J. Mungall, PhD^12*, Michael Crump, MD¹, Jan Delabie, MD, PhD^1*, Mary Gospodarowicz, MD^1*, David Hodgson, MD, MPH^1*, Michael Hong, MSc^1*, Vishal Kukreti, MD, FRCP, MSc¹³, John Kuruvilla, MD¹, Anca Prica, MD, MSc^1*, Rosemarie Tremblay-Lemay, MD, MSc^1*, Richard Tsang, MD^1* and Robert Kridel, MD¹

¹University Health Network, Princess Margaret Cancer Center, Toronto, ON, Canada
²Department of Biostatistics, Princess Margaret Cancer Center, Toronto, ON, Canada
³Department of Oncology, Oslo University Hospital, Oslo, Norway
⁴Department of Hematology, Aarhus University Hospital, Aarhus, Denmark
⁵Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
⁶Department of Pathology, Aarhus University Hospital, Aarhus, Denmark
⁷Department of Haematology, Princess Alexandra Hospital, Mater Research University of Queensland, Brisbane, QLD, Australia
⁸Princess Alexandra Hospital, Mater Research, University of Queensland, Brisbane, QLD, Australia
⁹Queen's University, Kingston, ON, Canada
¹⁰Queen's University, Department of Pathology and Molecular Medicine, Kingston, ON, Canada
¹¹Departments of Medicine and Oncology, Jewish General Hospital, Montreal, QC, Canada
¹²Canada's Michael Smith Genome Sciences Center, BC Cancer Agency and Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
¹³University Health Network, Princess Margaret Hospital, Toronto, ON, Canada

Ruben A.L. De Groen, MSc^1*, Fleur A De Groot^1*, Lorraine M. De Haan^2*, Tom van Wezel^2*, Troy Noordenbos^2*, Stefan Boehringer^3*, Ronald Van Eijk^2*, Richard Raghoo^4*, Dina Ruano^2*, Aniko Sijs-Szabo^1*, Liane te Boome, MD⁵, Valeska Terpstra^6*, Henriette Levenga^7*, Aline Nicolae^8*, Ward Posthuma, MD, PhD⁹, Isabelle Focke-Snieders^9*, Lizan Hardi^10*, Wietske den Hartog^11*, Lara H. Böhmer, MD^12*, Anke Van Den Berg, PhD¹³, Pim Mutseaers, MD^14*, Marjolein W.M. Van Der Poel¹⁵, Myrurgia Abdul Hamid^16*, F.J. Sherida H. Woei-a-Jin, MD MSc^17*, Ann Janssens, MD, PhD^18*, Thomas Tousseyn^19*, Judith Bovée^2*, Hendrik Veelken, MD, PhD¹, Steven T Pals, MD, PhD^20,21*, Arjan Diepstra, M.D., Ph.D.¹³, Marcel Nijland, MD, PhD^22*, Marie José Kersten, MD, PhD^21,23, Patty M. Jansen^2*, Arjen Cleven^2,24* and Joost S.P. Vermaat, MD, PhD¹

¹Department of Hematology, Leiden University Medical Center, Leiden, Netherlands
²Department of Pathology, Leiden University Medical Center, Leiden, Netherlands
³Leiden University Medical Center, Leiden, Netherlands
⁴Department of Radiology, LUMC, Leiden, Netherlands
⁵MCH, The Hague, NLD
⁶Pathology, Haaglanden MC, Den Haag, Netherlands
⁷Department of Hematology, Groene Hart Ziekenhuis, Gouda, Netherlands
⁸Groene Hart Hospital, Gouda, Netherlands
⁹Reinier de Graaf Hospital, Delft, Netherlands
¹⁰Department of Hematology, Alrijne Hospital, Leiderdorp, Netherlands
¹¹Department of Pathology, Alrijne Hospital, Leiderdorp, Netherlands
¹²Department of Hematology, Haga Teaching Hospital, The Hague, Netherlands
¹³Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
¹⁴Department of Hematology, Erasmus MC Cancer Center, Rotterdam, Netherlands
¹⁵Department of Hematology, Maastricht University Medical Center, Maastricht, Netherlands
¹⁶Maastricht University, Urmond, NLD
¹⁷Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium
¹⁸Department of Hematology, Universitaire Ziekenhuizen Leuven, Leuven, Belgium
¹⁹Department of Pathology, UZ Leuven, Leuven, Belgium
²⁰Department of Pathology, Academic Medical Center, Amsterdam, Netherlands
²¹Lymphoma and Myeloma Center Amsterdam-LYMMCARE, Amsterdam, Netherlands
²²Department of Hematology, University Medical Center Groningen and University of Groningen, Groningen, Netherlands
²³Department of Hematology, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Noord Holland, Netherlands
²⁴Department of Pathology and Medical Biology, University of Groningen, Groningen, Netherlands

Jan-Michel Heger^1,2*, Julia Mattlener^1,2*, Philipp Gödel, MD^1,3*, Hyatt Balke-Want, MD^1,2*, Noëlle Sieg, MD^1,2*, Nadine Kutsch, MD^1,3*, Kerstin Becker^4*, Jonathan Weiss, PhD^2*, H. Christian Reinhardt, MD^1,5*, Michael Hallek, MD^1,6, Peter Borchmann^1,3,7, Bastian von Tresckow, MD^1,5,7 and Sven Borchmann, MD^1,2,7*

¹Cancer Center Cologne Essen (CCCE), Cologne / Essen, Germany
²Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany
³University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany
⁴Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany
⁵Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
⁶Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany
⁷German Hodgkin Study Group (GHSG), Cologne, Germany

Laura Gleason^1*, Pierluigi Porcu, MD² and Neda Nikbakht, MD, PhD^1*

¹Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA
²Sidney Kimmel Cancer Center at Jefferson Health, Thomas Jefferson University, Philadelphia, PA

Kris Richardson, PhD^1*, Jorge J. Castillo, MD¹, Shayna Sarosiek, MD¹, Andrew R. Branagan, MD², Catherine A. Flynn, NP^1*, Kirsten Meid, MPH^1*, Carly Leventoff^1*, Timothy P White^1*, Megan Little^1*, Joshua Gustine, MPH^1*, Xia Liu, MD^1*, Amanda Kofides^1*, Shirong Liu, MD PhD^1*, Alexa Canning^1*, Julie Wolf^3*, Katherine Kacena^4*, Christopher J Patterson, MS, MPH^1*, Maria Luisa Guerrera, MD^1*, Nickolas Tsakmaklis^1*, Steven P Treon, MD, PhD¹ and Zachary R Hunter, PhD¹

¹Bing Center for Waldenstrom's macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA
²Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA
³Wolf Biostatistics, Nederland, CO
⁴Katherine Kacena Consulting, Natick, MA

David A. Russler-Germain, MD, PhD, BS¹, Kilannin Krysiak, PhD^2,3,4*, Cody Ramirez, PhD^1,3, Matthew Mosior, MSc^1,3*, Marcus P. Watkins, PhD^1*, Felicia Gomez, PhD^1,3*, Zachary Skidmore, MEng^1,3*, Lee Trani^1,3*, Feng Gao, MD, PhD, MPH^5*, Susan M. Geyer, PhD^6*, Amanda F. Cashen, MD^1,4, Neha Mehta-Shah, MD, MSCI^1,4, Brad S. Kahl, MD^4,7, Nancy L. Bartlett, MD^1,4, Izidore S. Lossos, MD⁸, Eric D. Hsi, MD⁹, Peter Martin, FRCPC, MD, MS¹⁰, John P. Leonard, MD¹¹, Malachi Griffith, PhD^1,3,12*, Obi L. Griffith, PhD^1,4,12* and Todd A. Fehniger, MD, PhD^1,4

¹Division of Oncology, Washington University School of Medicine, St. Louis, MO
²Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
³McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO
⁴Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
⁵Public Health Sciences Division, Washington University School of Medicine, St. Louis, MO
⁶Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN
⁷Division of Oncology, Washington University School of Medicine in St. Louis, Saint Louis, MO
⁸Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL
⁹Wake Forest Baptist Medical Center, Winston Salem, NC
¹⁰Meyer Cancer Center, Weill Cornell Medical College-New York Presbyterian Hospital, New York, NY
¹¹Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY
¹²Department of Medicine, Washington University School of Medicine, St. Louis, MO

Piers Blombery, MBBS^1,2,3, Wencke Walter, PhD^4*, Stephan Hutter, PhD^4*, Constance Baer, PhD⁴, Maki Sakuma^4*, Heiko Mueller, PhD^4*, Simon Wu, MBBS^3*, Imogen R Caldwell, FRACP, FRCPA³, Wolfgang Kern, MD⁴, Manja Meggendorfer, PhD⁴, Claudia Haferlach, MD⁴ and Torsten Haferlach, MD⁴

¹Torsten Haferlach Leukaemiediagnostik Stiftung, Munich, Germany
²University of Melbourne, Melbourne, Australia
³Peter MacCallum Cancer Centre, Melbourne, Australia
⁴MLL Munich Leukemia Laboratory, Munich, Germany

Matthew E Stokes, PhD^1*, Kerstin Wenzl, PhD², C. Chris Huang, PhD^3*, Maria Ortiz Estevez, PhD^4*, Matthew J. Maurer, DSc⁵, Nicholas Stong, PhD^1*, Patrick Hagner, PhD^3*, Yumi Nakayama, PhD^3*, Chih-Chao Hsu, PhD^3*, Samuel A Danziger, PhD^6*, Fadi Towfic, PhD^7*, Rebecca L. King, MD⁸, Joel S. Parker, PhD^9*, Brian K. Link, MD¹⁰, Susan L. Slager, PhD⁵, Vivekananda Sarangi^5*, Yan Asmann, PhD¹¹, Joseph P. Novak^2*, Akshay Sudhindra^12*, Stephen M. Ansell, MD, PhD², Thomas M. Habermann, MD¹³, Grzegorz S. Nowakowski, MD², James R. Cerhan, MD, PhD⁵, Anne J. Novak, PhD² and Anita K. Gandhi, PhD³

¹Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, NJ
²Division of Hematology, Mayo Clinic, Rochester, MN
³Translational Medicine Hematology, Bristol Myers Squibb, Summit, NJ
⁴Informatics and Predictive Sciences, Bristol Myers Squibb, Madrid, Spain
⁵Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
⁶Informatics and Predictive Sciences, Bristol Myers Squibb, Seattle, WA
⁷Informatics and Predictive Sciences, Bristol Myers Squibb, San Diego, CA
⁸Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁹LifeEDIT Therapeutics, Research Triangle Park, NC
¹⁰Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa, Iowa City, IA
¹¹Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL
¹²Clinical Research and Development, Bristol Myers Squibb, Summit, NJ
¹³Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN

Francesco Vallania, PhD^1*, Victoria Cheung, PhD^1*, Michael D. Zamba, MS^1*, Joyce Liu, PhD^1*, Amit Pasupathy, BS^1*, Hayley Donnella, PhD^1*, Mitch Bailey, MS^1*, Maggie Louie, PhD^1*, Jimmy Lin, MD, PhD, MHS^1*, Karin Havenith, PhD^2*, Yajuan Qin, MD, PhD^3*, Serafino Pantano, PhD^4*, Jens Wuerthner, MD, PhD⁴ and Patrick H van Berkel, PhD^2*

¹Freenome, San Francisco, CA
²ADC Therapeutics (UK) Ltd, London, United Kingdom
³ADC Therapeutics America, Inc, Murray Hill, NJ
⁴ADC Therapeutics SA, Épalinges, Switzerland

Haifaa Abdulhaq, MD¹, Omar Mahmood, MD², Calvin Kuan Jung Chen, DO^3*, Azra Borogovac, MD⁴, Matthew Wieduwilt, MD^4*, Anand Annan^5*, Yueqi Yan, PhD^6* and Maher Albitar, MD^7*

¹University of California, San Francisco, Fresno, CA
²University of California, San Francisco-Fresno, Fresno, CA
³Pathology Associates, Clovis, CA
⁴Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK
⁵University of Oklahoma, Oklahoma City
⁶Health Science Research Institute, University of California Merced, Merced
⁷Genomic Testing Cooperative, Irvine, CA