Arend von Stackelberg, MD¹, Jean-Pierre Bourquin, MD, PhD², Martin Zimmermann, PhD^3*, Tamas Revesz, MD PhD^4*, Andishe Attarbaschi, MD^5*, Alina Ferster, MD⁶, Lucie Sramkova, MD^7*, Thomas Leth Frandsen, MD, PhD^8*, Päivi Maria Lähteenmäki, MD, PhD^9*, Ronit Elhasid, MD¹⁰, Hidemi Toyoda, MD, PhD^11*, Peter M. Hoogerbrugge, MD, PhD¹², Inga M. Johannsdottir, MD^13*, Ximo Duarte, MD^14*, Denise Bonney, MD^15*, Vaskar Saha, MD, PhD^16,17*, Ingo G. Steffen, MD^18*, Andrej Lissat, MD^19*, Christiane Chen-Santel, MD^20*, Cornelia Eckert, PhD^21*, Andre Baruchel, MD²², Arnaud Petit, MD, PhD^23*, Hélène Cavé, PharmD, PhD^24*, Carmelo Rizzari^25*, Giovanni Cazzaniga, PhD^26*, Luciana Vinti, PhD²⁷, Pierre Rohrlich, MD^28* and Franco Locatelli, Prof., MD, PhD²⁹

¹Pediatric Oncology and Hematology, Charité, Med. Univ., Berlin, Berlin, Germany
²University Children's Hospital Zurich, Zurich, Switzerland
³Department of Pediatric Hematology and Oncology, Hannover Medical School (MHH), Hannover, Germany
⁴Dept of Haematology & Oncology, Women's & Children's Hospital, Adelaide, Australia
⁵Department of Pediatric Hematology and Oncology, St. Anna Children’s Hospital, Medical University of Vienna, Vienna, Austria
⁶Pediatric Hemato-Oncology, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium
⁷Department of Pediatric Hematology and Oncology, University Hospital Motol, Prague, Czech Republic
⁸Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⁹Department of Pediatric and Adolecent Medicine, Turku University Hospital, Turku, Finland
¹⁰Pediatric Hemato-Oncology Department, Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
¹¹Department of Pediatrics, Mie University Graduate School of Medicine, Mie, Japan
¹²Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
¹³Oslo University Hospital, Oslo, Norway
¹⁴Instituto Português de Oncologia de Lisboa, Lisboa, Portugal
¹⁵Dept of Peadiatric Haematology, Royal Manchester Childrens' Hospital, Manchester, United Kingdom
¹⁶Children's Cancer Group, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom
¹⁷Tata Translational Cancer Research Centre, Tata Medical Center, Kolkata, India
¹⁸Department of Pediatric Oncology/Hematology, Charite Medical Center, Berlin, Germany
¹⁹Pediatric Oncology and Hematology, Charité Universitätsmedizin Berlin, Berlin, Germany
²⁰Department of Pediatrics, Rostock University Medical Center, Rostock, Germany
²¹Department of Pediatric Oncology and Hematology, Charité University Medical Center, Berlin, Germany
²²Pediatric Hematology and Immunology Department, Hôpital Universitaire Robert Debré (APHP and Université Paris Cité), Paris, France
²³Department of Pediatric Hematology and Oncology, Hôpital Armand Trousseau, APHP, Sorbonne Université, Paris, France
²⁴Department of Genetics, AP-HP Robert Debré, Paris Diderot University, Paris, France
²⁵Pediatric Hematology-Oncology Unit, University of Milano-Bicocca, MBBM Foundation, San Gerardo Hospital, Monza, Italy
²⁶Tettamanti Research Center, Pediatrics, University of Milan Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, MZ, Italy
²⁷Department of Hematology/Oncology , Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Sapienza, University of Rome, Rome, Italy
²⁸Pediatric Hematology Department, CHU Nice, Nice, France
²⁹Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy

Patrice Nasnas, MD^1*, Elias Jabbour, MD¹, Nicholas Short, MD¹, Koji Sasaki, MD¹, Farhad Ravandi, MD¹, Nitin Jain, MD², Naval Daver, MD¹, Naveen Pemmaraju, MD¹, Musa Yilmaz, MD², Tapan M. Kadia, MD², Rebecca Garris^1*, Guillermo Garcia-Manero, MD³, Courtney D. DiNardo, MD, MSCE¹, Marina Konopleva, MD, PhD⁴, William G. Wierda, MD, PhD⁵, Monica Kwari, BSN¹, Christopher Loiselle, BS^1*, Anna Milton^1*, Juan Rivera^1*, Glenda Banks^1* and Hagop Kantarjian, MD⁶

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX
⁵The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Jayastu Senapati, MD, MBBS, DM^1*, Nicholas Short, MD², Yesid Alvarado, MD¹, Jan A. Burger, MD, PhD¹, Nitin Jain, MD³, Marina Konopleva, MD, PhD⁴, Farhad Ravandi, MD¹, Courtney D. DiNardo, MD, MSCE¹, Lucia Masarova, MD¹, Koji Sasaki, MD¹, Philip A. Thompson, MBBS¹, Alessandra Ferrajoli², Jovitta Jacob^1*, Ejiroghene Mayor, BSN, RN^1*, Anna Milton^1*, Christopher Loiselle, BS^1*, Rebecca Garris^1*, Hagop Kantarjian, MD⁵ and Elias Jabbour, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
³Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Erin Guest, MD¹, John Kairalla, PhD^2*, Meenakshi Devidas, PhD, MBA³, Emily Hibbitts, MS^4*, Andrew J. Carroll, PhD⁵, Nyla A. Heerema, PhD⁶, Holly Kubaney, MSN, RN, PPCNP-BC, CPHON^7*, Amanda August, PharmD^1*, Melinda Pauly, MD⁸, Daniel Wechsler, MD, PhD^9*, Rodney R. Miles, MD, PhD¹⁰, Joel M. Reid, PhD^11*, Cynthia Kihei, BSN^12*, Lia Gore¹³, Elizabeth A. Raetz, MD¹⁴, Stephen P. Hunger, MD¹⁵, Mignon L. Loh, MD¹⁶ and Patrick A. Brown, MD¹⁷

¹Children's Mercy Kansas City, Kansas City, MO
²Department of Biostatistics, University of Florida, Children's Oncology Group, Gainesville, FL
³Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN
⁴Children's Oncology Group, Gainsville, FL
⁵Department of Genetics, University of Alabama at Birmingham, Birmingham, AL
⁶Department of Pathology, The Ohio State University, Columbus, OH
⁷Dell Children's Medical Center of Central Texas, Austin, TX
⁸Emory University, Atlanta, GA
⁹Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, GA
¹⁰Dept. of Pathology and ARUP Institute for Clinical & Experimental Pathology, University of Utah, Primary Children's Hospital, Salt Lake City, UT
¹¹Department of Oncology, Mayo Clinic, Rochester, MN
¹²Pediatric Hematology/Oncology, Saint Mary's Hospital, West Palm Beach, FL
¹³Children's Hospital Colorado, University of Colorado, Aurora, CO
¹⁴Division of Pediatric Hematology and Oncology, Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders, NYU Langone Health, New York, NY
¹⁵Department of Pediatrics, Division of Oncology and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
¹⁶Division of Hematology, Oncology, BMT, and Cellular Therapies, Seattle Children's Hospital, Seattle, WA
¹⁷Bristol Myers Squibb, Princeton, NJ

Cyril Salek^1,2*, Frantisek Folber, MD, PhD^3*, Stepan Hrabovsky, MD, PhD^3*, Zdenek Koristek, MD, PhD^4*, Jan M Horacek, MD, PhD^5,6*, Eva Fronkova^7*, Petr Soukup, MD^1*, Katerina Benkova, MD^4*, Petr Cetkovsky, MD, PhD^1,8*, Jan Trka⁹ and Michael Doubek, MD, PhD³

¹Institute of Hematology and Blood Transfusion, Prague, Czech Republic
²Charles University, First Faculty of Medicine, Prague, Czech Republic
³Department of Internal Medicine - Hematology and Oncology, University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic
⁴Department of Hematooncology, University of Ostrava, Faculty of Medicine, Ostrava, Czech Republic
⁵Department of Internal Medicine IV – Hematology, University Hospital Hradec Kralove, Hradec Kralove, Hradec Kralove, Czech Republic
⁶Internal Medicine, University of Defence, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
⁷CLIP, Dept. of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic
⁸Institute of Clinical and Experimental Hematology, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic
⁹CLIP - Childhood Leukaemia Investigation Prague, Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

Wenjuan Yu, MD^1*, Hongsheng Zhou^2*, Lijing Shen^3*, Dong Chen^4*, Xiang Zhang^5*, Yanan Zhu^6*, Xin Huang, Ph.D.^5*, Ying Lu^7*, Jian Hou^3*, Qifa Liu, MD² and Jie Jin, PhD⁵

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Department of Hematology, Renji Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China
⁴Department of Hematology, Yinzhou Hospital Affiliated to Medical School of Ningbo University, Ningbo, China
⁵Department of Hematology, The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⁶Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
⁷The affiliated people’s hospital of Ningbo University, Ningbo, China, Ningbo, China

Kimberly B. Johansson, BA^1,2, Megan Gauthier, MD^1*, Feng Gao, MD, PhD, MPH^3* and Daniel C. Link, MD¹

¹Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²Medical Scientist Training Program, Washington University in St. Louis, Saint Louis, MO
³Public Health Sciences Division, Washington University School of Medicine, St. Louis, MO

Manuel Torres-Diz, PhD¹, Clara Reglero, PhD^2*, Catherine D Falkenstein, BS^3*, Zhiwei Ang, PhD^1*, Priyanka Sehgal, PhD^1*, Caleb Radens, PhD^4*, Yoseph Barash, PhD^4*, Sarah K Tasian, MD³, Adolfo Ferrando, M.D., PhD^2,5,6,7* and Andrei Thomas-Tikhonenko, PhD^8,9,10

¹Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, PA
²Institute for Cancer Genetics, Columbia University, New York, NY
³Division of Oncology and Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA
⁴Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
⁵Department of Pediatrics, Columbia University Medical Center, New York, NY
⁶Department of Systems Biology, Columbia University, New York, NY
⁷Department of Pathology, Columbia University Medical Center, New York, NY
⁸Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
⁹Division of Experimental Pathology, Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, PA
¹⁰Professor of Pathology & Laboratory Medicine and Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia

Weiyang Liu, PhD^*, Yuanfang Liu, MD, PhD^*, Yongmei Zhu, PhD^*, Xiangqin Weng, Master^*, Cheng Wang, Master^*, Wanyan Ouyang, MD, PhD^*, Jie Xu, MD, PhD, Jin Wang, MD, PhD^* and Jian-Qing Mi, M.D., Ph.D.^*

Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Angus Hodder, MBBS^1*, Avijeet K Mishra^1*, Katherine Clesham, MD PhD^2*, Susan Baird, MD^3*, Kaljit Bhuller^4*, Ismail Bisho^5*, Denise Bonney^6*, Anna Castleton, FRCPath^7*, Michelle Cummins^8*, Emmy Dickens^9*, Lindsay George, PhD, FRCPath^10*, Sara Ghorashian, FRCPath, PhD¹¹, Brenda Gibson^12*, Chris Hasley^13*, Nicholas Heaney^14*, Rachael E Hough, MD^15,16*, Danielle Ingham^17*, Galina Jigoulina^18*, Katherine Lindsay^19*, Donna Lancaster^20*, Majid Madni^21*, Andrea Malone^22*, Bethany Mitchell^23*, Anthony V. Moorman²⁴, John Moppett, PhD FRCPath^25*, Vanessa McLelland^25*, Jayashree Motwani, MD^26*, Emma Nicholson, MD, PhD^20*, Caroline Osborne^27*, Katharine Patrick, MD^28*, Lamia Samrin^29*, Sanjay Tewari, FRCPath, MBBS^30*, Indu Rakesh Thakur, FRCPath, MD, MBBS^31*, Sujith Samarasinghe, PhD, FRCPath^32*, Ajay Vora, MD¹ and David O'Connor, MBBS, PhD, FRCPath (Haem)^33*

¹Department of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom
²Department of Haematology, University College London Hospitals NHS Trust, London, United Kingdom
³Department of Haematology, Royal Hospital for Sick Children, Edinburgh, United Kingdom
⁴University Hospitals of Leicester NHS Trust, Leicester, United Kingdom
⁵Haematology, Oxford University Hospital NHS Trust, Oxford, United Kingdom
⁶Royal Manchester Children's Hospital, Manchester, GBR
⁷Haematology, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
⁸Department of Haematology, Bristol Children's Hospital, Bristol, GBR
⁹Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR
¹⁰Birmingham Children's Hospital, Birmingham, GBR
¹¹Department of Hematology, Great Ormond Street Hospital for Children, London, United Kingdom
¹²The Royal Hospital for Children, Glasgow, United Kingdom
¹³School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
¹⁴Royal Hospital For Children, Glasgow, GBR
¹⁵Haematology, University College London Hospital, London, United Kingdom
¹⁶Haematology, UCLH, London, United Kingdom
¹⁷Haematology, Leeds Children's Hospital, Leeds, GBR
¹⁸Haematology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
¹⁹Haematology, Alder Hey Children's Hospital Trust, LIverpool, United Kingdom
²⁰The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom
²¹Nottingham University Hospitals, Nottingham, GBR
²²Our Lady's Children Hospital, Crumlin, IRL
²³Haematology, Royal Belfast Hospital for Sick Children, Belfast, United Kingdom
²⁴Wolfson Childhood Cancer Research Centre, Newcastle University, Newcastle, United Kingdom
²⁵Department of Haematology, Bristol Children's Hospital, Bristol, United Kingdom
²⁶Birmingham Children's Hospital, Birmingham, United Kingdom
²⁷Alder Hey Children's Hospital Trust, LIverpool, United Kingdom
²⁸Haematology, Sheffield Children's NHS Foundation Trust, London, United Kingdom
²⁹Great Ormond Street Hospital, London, United Kingdom
³⁰Haematology, The Royal Marsden, London, United Kingdom
³¹Children's Hospital For Wales, Cardiff, GBR
³²Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, United Kingdom
³³Cancer Institute, University College London, London, United Kingdom

Manling Chen^*, Shaowei Qiu, MD^*, Xiaoyu Liu^*, Ting Zhang, MD^*, Huizhen He^*, Runxia Gu^*, Yingxi Xu^*, Haiyan Xing, MS^*, Kejing Tang, BS^*, Zheng Tian^*, Qing Rao, MS^*, Min Wang^* and Jianxiang Wang, MD

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China