Jing Li, PhD^1*, Ju Gao, PhD^2*, Ansheng Liu^3*, Wei Liu^4*, Hao Xiong^5*, Changda Liang, MD, PhD^6*, Yongjun Fang, PhD^7*, Yunpeng Dai, PhD^8*, Jingbo Shao^9*, Hui Yu^10*, Lingzhen Wang, PhD^11*, Li Wang^12*, Liangchun Yang^13*, Mei Yan, MD^14*, Xiaowen Zhai, MD, PhD^15*, Xiaodong Shi, MD^16*, Xin Tian, PhD^17*, Xiuli Ju, MD^18*, Yan Chen, MD^19*, Jing Wang^20*, Leping Zhang, MD, PhD^21*, Hui Liang^22*, Sen Chen^23*, Jingrong Zhang^24*, Haixia Cao^25*, Jiao Jin^26*, Qun Hu, MD, PhD^27*, Junlan Wang^28*, Yilin Wang^29*, Min Zhou, MD^30*, Yueqin Han^31*, Rong Zhang, MD and PhD^32*, Weihong Zhao, PhD^33*, Aimin Li^34*, Limin Lin^35*, Ruidong Zhang, MD, PhD^36*, Chao Gao^37*, Liting Xu^38*, Yuanyuan Zhang, MD^36*, Jia Fan^36*, Ying Wu^36*, Wei Lin^36*, Jiaole Yu, PhD, MD^36*, Peijing Qi^36*, Pengli Huang^36*, Xiaoxia Peng^39*, Yaguang Peng^39* and Huyong Zheng, MD, PhD³⁶

¹Hematology Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, WY, China
²West China Second University Hospital, Sichuan University; Key Laboratory of Chronobiology (Sichuan University), National Health Commission of China, Chengdu, China
³Department of Hematology/Oncology, Xian Children's Hospital, Xi'An, China
⁴Department of Hematology/Oncology, Children's hospital of Henan province, Zhengzhou, China
⁵Wuhan Children’s Hospital, Wuhan, China
⁶Jiangxi Provincial Children's Hospital, Nanchang, China
⁷Children's Hospital of Nanjing Medical University, Nanjing, China
⁸Shandong First Medical University Affiliated Shandong Provincial Hospital, Jinan, China
⁹Shanghai Children's Hospital, Shanghai, China
¹⁰Union Hospital,Tongji Medical College, Huazhong University of Science and Techno, Wuhan, CHN
¹¹The affiliated hospital of qingdao university, Qingdao, China
¹²Children's Hospital of Hebei Province, Shijiazhuang, China
¹³Xiangya Hospital Central South University, Changsha, China
¹⁴The First Affiliated Hosptial of Xinjiang Medical University, Urumqi, China
¹⁵Children's Hospital of Fudan University, Shanghai, China
¹⁶Capital institute of Pediatrics' Children's Hospital, Beijing, China
¹⁷Kunming Children's Hospital, Kunming, China
¹⁸Qilu hospital of Shandong university, Jinan, China
¹⁹Children's Hospital of Guizhou province, Affiliated Hospital of Zhunyi Medical University, Zunyi, China
²⁰Children's hospital of Shanxi province, Xian, China
²¹Department of Hematology, Peking University People's Hospital, Beijing, China
²²Women and Children's Hospital, Qingdao University, Qingdao, China
²³Tianjin Children's Hospital, Tianjin, China
²⁴Guiyang Children's Hospital, Guiyang, China
²⁵Qinghai Women's and Children's Hospital, Xining, China
²⁶The Affiliated Hospital of Guizhou Medical University, GuiYang, China
²⁷Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
²⁸Northwest Women's and Children's Hospital, Xian, China
²⁹Linyi People's Hospital, Linyi, China
³⁰Chengdu Women's and Children's Central Hospital, Chengdu, China
³¹Liaocheng Children's Hospital, Liaocheng, China
³²Sichuan Provincial People’s Hospital, Chengdu, China
³³Peking University First Hospital, Beijing, China
³⁴Yantai Yuhuangding Hospital, Yantai, China
³⁵Second Affiliated Hospital of Shantou University Medical College, Shantou, China
³⁶Hematology Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China
³⁷Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
³⁸Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, China
³⁹Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China

Alfonso Piciocchi, MS^1*, Valentina Arena, MS^2*, Monica Messina^1*, Sonia Maria Orlando^1*, Raffaele Palmieri, MD^3*, Luca Maurillo, MD^3*, Maria Ilaria Del Principe, MD^3*, Paola Fazi, MD^1*, Marco Vignetti, MD^1,4*, Francesco Buccisano, MD³ and Adriano Venditti, MD⁵

¹GIMEMA Foundation, Rome, Italy
²GIMEMA Foundation, Roma, Italy
³Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁴Dept of Cellular Biotechnologies and Hematology, University "la Sapienza", Roma, Italy
⁵Hematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy

Sharlene Dong, MD¹, Naveen Premnath, M.D.^2*, Navid Sadeghi, MD^3,4, Radhika Kainthla, MD^3,4*, Stephen S. Chung, MD⁵, Madhuri Vusirikala, MD^3*, Robert H. Collins, M.D.⁶, Hsiao C. Li, MD^3,4 and Yazan F. Madanat, MD^6,7

¹Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
²Division of Hematology and Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
³Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX
⁴Parkland Health and Hospital System, Dallas, TX
⁵Division of Hematologic Malignancies and Cellular Therapy, Dept of Internal Medicine, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁶Division of Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
⁷Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX

Fadi Haddad, MD^1*, Georgio Medawar^2*, Rashmi Kanagal-Shamanna, MD³, Hector Alvarez^4*, Sanam Loghavi, MD⁵, Naval Daver, MD⁶, Sherry A. Pierce, BSN, BA^1*, Elias Jabbour, MD¹, Tapan M. Kadia, MD⁷, Nicholas Short, MD⁸, Courtney D. DiNardo, MD, MSCE¹, Gautam Borthakur, MD¹, Hussein A Abbas, MD, PhD¹, Naveen Pemmaraju, MD¹, Guillermo Garcia-Manero, MD⁹, Farhad Ravandi, MD¹, Hagop Kantarjian, MD¹⁰ and Musa Yilmaz, MD⁷

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Leukemia, The University of Texas MD Anderson Cancer Center, Houston
³Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX
⁴Hematopathology, The University of Texas MD Anderson Cancer Center, Houston
⁵Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁸Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Noam E. Kopmar, MD^1,2, Megan Othus, PhD^3,4, Olivia Gilbert, BA^1*, Kelda Schonhoff, PA-C^2*, Carole M. Shaw, BA^5*, Kathryn Russell, ARNP^2*, Anna B. Halpern, MD^6,7,8, Jacob S. Appelbaum, MD, PhD^7,9, Roland B. Walter, MD, PhD, MS^7,10,11, Paul C. Hendrie, MD, PhD^6,7, Bart L. Scott, MD^12,13 and Mary-Elizabeth M. Percival, MD^2,6

¹Division of Hematology, University of Washington, Seattle, WA
²Fred Hutchinson Cancer Center, Seattle, WA
³Department of Biostatistics, University of Washington School of Public Health, Seattle, WA
⁴Division of Public Health, Fred Hutchinson Cancer Research Center, Seattle, WA
⁵Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁶Department of Medicine, University of Washington, Seattle, WA
⁷Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁸Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁹Department of Medicine, Division of Hematology, Seattle, WA
¹⁰Division of Hematology, Dept of Medicine, University of Washington Medical Center, Seattle, WA
¹¹Department of Epidemiology, University of Washington Medical Center, Seattle, WA
¹²Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, WA
¹³Fred Hutchinson Cancer Research Center, Seattle, WA

Tong-Yoon Kim, MD^1*, Byung-Sik Cho, M.D., Ph.D.^2,3*, Daehun Kwag^4*, Jong Hyuk Lee, MD^5*, Gi June Min, M.D., Ph.D.³, Sung-Soo Park, M.D., Ph.D.^3*, Silvia Park, M.D., Ph.D.^6*, Jae-Ho Yoon, M.D., Ph.D.³, Sung-Eun Lee, MD^1,7*, Ki-Seong Eom, MD, PhD^8*, Yoo-Jin Kim, M.D., Ph.D.³, Seok Lee, M.D., Ph.D.³, Hee-Je Kim, M.D., Ph.D.³, Chang-Ki Min, MD, PhD^3*, Seok-Goo Cho, M.D., Ph.D.^3*, Jong Wook Lee, M.D., Ph.D.³, Myungshin Kim, MD, PhD^9* and Yonggoo Kim^9*

¹Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
²Department of Hematology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
³Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁴Department of Hematology, Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁵Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
⁶Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Gangnam-Gu, Korea, Republic of (South)
⁷Catholic Blood and Marrow Transplantation Center, Division of Hematology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁸Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KOR
⁹Department of Laboratory Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Seoul, Korea, Republic of (South)

Claire Schwab^1*, Ruth E Cranston, PhD^1*, Emily Winterman^1*, Jelena Jovanovic, PhD^2*, Zoya Kingsbury^3*, Terena James^3*, Martina Mijuskovic^3*, Enes Tuc^2*, Richard Dillon, MA PhD MRCP FRCPath², Brenda Gibson^4*, Mark Ross, PhD^3* and Christine J. Harrison, PhD, FRCPath¹

¹Leukaemia Research Cytogenetics Group, Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
²Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
³Illumina Cambridge Ltd, Cambridge, United Kingdom
⁴The Royal Hospital for Children, Glasgow, United Kingdom

Agnieszka Pluta^1*, Marta Anna Sobas, MD, PhD^2*, Damian Mikulski, MD^1,3*, Kinga Krawiec, MD^1*, Magdalena Czemerska^4*, Bozena Katarzyna Budziszewska, MD, PhD^5*, Tomasz Wróbel⁶, Marzena Watek, MD PhD^5*, Ewa Lech-Marańda, MD, PhD^7*, Tomasz Gromek, MD, PhD^8*, Dorota Hawrylecka, MD, PhD^8*, Marek Hus, MD, PhD^8*, Ewa Zarzycka, MD^9*, Jan Zaucha, MD, PhD^9*, Anna Armatys, MD^10*, Grzegorz Helbig, MD, PhD^10*, Jolanta Oleksiuk, MD, PhD^11*, Jaroslaw Piszcz, MD PhD¹¹, Andrzej Szczepaniak, MD, PhD^12*, Lidia Gil, MD, PhD¹³, Rafal Becht, MD, PhD^14*, Wojciech Fendler, MD, PhD^3*, Sebastian Giebel, MD, PhD^15* and Agnieszka Wierzbowska, MD, PhD¹

¹Department of Hematology, Medical University of Lodz, Multidisciplinary Provincial Centre of Traumatology and Oncology Nicolas Copernicus in Lodz, Lodz, Poland
²Department of Hematology, Blood Neoplasm and Bone Marrow Transplantation, Hosp. Clinico Univ. de Santiago de Compostela, Santiago de Compostela, Spain
³Department of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland
⁴Department of Hematology, Medical University of Lodz, Multidisciplinary Provincial Centre of Traumatology and Oncology Nicolas Copernicus in Lodz, Lódz, Poland
⁵Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁶Department and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation Wroclaw Medical University, Wroclaw, Poland
⁷Hematology Department, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁸Department of Hematooncology and Bone Marrow Transplantation, Medical University, Lublin, Poland
⁹Department of Hematology and Transplantology, Medical University, Gdansk, Poland
¹⁰Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland
¹¹Department of Hematology, Medical University of Bialystok, Bialystok, Poland
¹²Department of Hematology and Bone Marrow Transplantation, Medical University, Poznan, Poland
¹³Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
¹⁴Clinical Department of Oncology, Chemotherapy and Cancer Immunotherapy, Pomeranian Medical University, Szczecin, Poland
¹⁵Department of Bone Marrow Transplantation and Hematology-Oncology, Maria Sklodowska-Curie Cancer Center and Institute of Oncology, Gliwice, Poland

Dennis Lee, MD¹, Tyler Augi^2*, Kata Alilovic, MS^3*, Nuria Mencia Trinchant, PhD^4*, Eti Sinha, BS⁵, Jorge Contreras, MD^6*, Michael Samuel, MD^4*, Pinkal Desai, MD, MPH⁷, Michael Kluk, MD, PhD^8*, Brianna N Smith, MD, MS⁹, Gail J. Roboz, MD⁴, Ellen Ritchie, MD⁴, Michael R. Savona, MD¹⁰, Monica L. Guzman, PhD¹¹ and Justin D. Kaner, MD¹²

¹Department of Medicine, Weill Cornell Medicine, NEW YORK, NY
²Weill-Cornell Medicine, New York, NY
³Cornell University, Ithaca, NY
⁴Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
⁵Caryl & Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY
⁶Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, NY
⁷Weill Cornell Medical College, New York, NY
⁸Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY
⁹Department of Medicine; Department of Pediatrics; Program in Cancer Biology, Vanderbilt University School of Medicine, Franklin, TN
¹⁰Vanderbilt University School of Medicine, Nashville, TN
¹¹Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
¹²Department of Medicine, Division of Hematology and Medical Oncology, Leukemia Program, Weill-Cornell Medicine, Syosset, NY

Shota Yoshida, MD^1*, Masahiro Onozawa, M.D, Ph.D.^1*, Naoki Miyashita, M.D.^1*, Hiroyuki Kimura, M.D.^1*, Shogo Takahashi, M.D.^1*, Shota Yokoyama^1*, Toshihiro Matsukawa, M.D., Ph.D.^1*, Shinsuke Hirabayashi, M.D, Ph.D.^2*, Akio Mori, MD, PhD³, Takeshi Kondo⁴, Daisuke Hidaka, M.D., Ph.D.^5*, Koichiro Minauchi, M.D, Ph.D.^6*, Akio Shigematsu, M.D., Ph.D.⁷, Junichi Hashiguchi, M.D., Ph.D.^8*, Tetsuyuki Igarashi, M.D.^9*, Yasutaka Kakinoki, M.D., Ph.D.^10*, Yutaka Tsutsumi, M.D., Ph.D.^11*, Hiroshi Iwasaki, M.D, Ph.D.^12*, Hajime Kobayashi, M.D, Ph.D.^13*, Yoshihito Haseyama, M.D, Ph.D.^14*, Katsuya Fujimoto, M.D, Ph.D.^15*, Toshimichi Ishihara, M.D., Ph.D.^16*, Hajime Sakai, M.D, Ph.D.¹⁷, Satoshi Iyama, M.D, Ph.D.^18* and Takanori Teshima, M.D., Ph.D.¹

¹Department of Hematology, Hokkaido University Faculty of Medicine, Sapporo, Japan
²Department of Pediatrics, Hokkaido University Hospital, Sapporo, Japan
³Blood Disorders Center, Aiiku Hospital, Sapporo, Japan
⁴Aiiku Hospital, Sapporo, Japan
⁵Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan
⁶Department of Hematology, Sapporo City General Hospital, Sapporo, Japan
⁷Department of Hematology, Kushiro Rosai Hospital, Kushiro, Japan
⁸Department of Hematology, Kitami Red Cross Hospital, Kitami, Japan
⁹Department of Hematology, Tenshi Hospital, Sapporo, HOK, Japan
¹⁰Department of Hematology, Asahikawa City Hospital, Asahikawa, HOK, Japan
¹¹Department of Hematology, Hakodate Municipal Hospital, Hakodate, Japan
¹²Department of Hematology, Sapporo Kosei General Hospital, Sapporo, Japan
¹³Department of Hematology, Obihiro Kosei Hospital, Obhiro, Japan
¹⁴Department of Hematology, Tonan Hospital, Sapporo, Japan
¹⁵Department of Hematology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan
¹⁶Department of Hematology, Kin-ikyo Chuo Hospital, Sapporo, Japan
¹⁷Department of Hematology, Teine Keijinkai Hospital, Sapporo, Japan
¹⁸Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan

Li Yanyan, MD^1,2*, Haixia Zhou^1,2*, Chaoling Wan^1,2*, Mingzhu Xu^1,2*, Chongsheng Qian^1,2*, Tongtong Zhang^1,2*, Haiping Dai^3,4*, AiNing Sun^1,2*, Depei Wu^5,6 and Shengli Xue^1,7*

¹National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Soochow, China
²Institute of Blood and Marrow Transplantation of Soochow University, Blood Cooperative Innovation Center,Soochow University, Soochow, China
³Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Suzhou, China
⁴Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
⁵Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
⁶National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Institute of Blood and Marrow Transplantation of Soochow University, Suzhou, China
⁷Institute of Blood and Marrow Transplantation of Soochow University, Blood Cooperative Innovation Center, Soochow University, Soochow, China

Daehun Kwag^1,2*, Su Yeon Bang, MD^1,2*, Jong Hyuk Lee, MD^1,3*, Gi June Min, M.D., Ph.D.^1,2, Sung-Soo Park, M.D., Ph.D.^1,2*, Silvia Park, M.D., Ph.D.^1,2*, Jae-Ho Yoon, M.D., Ph.D.^1,2, Sung-Eun Lee, MD^1,2*, Ki-Seong Eom, M.D., Ph.D.^1,2*, Yoo-Jin Kim, M.D., Ph.D.^1,2, Seok Lee, M.D., Ph.D.^1,2, Hee-Je Kim, M.D., Ph.D.^1,2, Chang-Ki Min, MD, PhD^1,2*, Seok-Goo Cho, M.D., Ph.D.^2*, Jong Wook Lee, M.D., Ph.D.² and Byung-Sik Cho, M.D., Ph.D.^1,2*

¹Leukemia Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
²Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
³Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

Xinan Pan, PhD^1*, Gao Mengge^2*, Ke Wang^3*, Yu Wang^4*, Jun Kong^5*, Yuqian Sun, MD^6*, Xiaosu Zhao^4,7* and Xiao Jun Huang, MD⁸

¹Peking University People’s Hospital,Peking University Institute of Hematology, ???, AL, China
²Peking University People’s Hospital,Peking University Institute of Hematology, Beijing, FL, China
³Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁴Peking University People’s Hospital, Beijing, China
⁵Peking University People’s Hospital,Peking University Institute of Hematology, Beijing, China
⁶Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of HSCT, Peking University, Beijing, China
⁷Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematology Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁸Peking University People’s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China

Lei-Ming Cao^1*, Ya-Lan Zhou^1*, Ming-Yue Zhao^1*, Li-Xia Liu^2*, Hao Jiang^1*, Ying-Jun Chang¹, Qian Jiang^1*, Lan-Ping Xu^1*, Xiao-Hui Zhang^1*, Xiao-Jun Huang^1,3* and Guo-Rui Ruan^1*

¹Peking University People’s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, National Clinical Research Center for Hematologic Disease, Beijing, China
²Acornmed Biotechnology Co., Ltd., Beijing, China
³Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China

Andrea Priscila Hernandez Perez, MD¹, Daniel Cabello Modesto, MD^2* and Roberta Demichelis, MD³

¹Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, MEXICO, Mexico
²Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
³Hematology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, Mexico City, Mexico

Tarinee Rungjirajittranon, M.D.^1,2, Theerapat Siriwannangkul, M.D.^1*, Nattawut Leelakanok, Ph.D.^3*, Smith Kungwankiattichai, M.D.^4*, Wannaphorn Rotchanapanya, M.D.^5*, Pongthep Vittayawacharin, M.D.^1*, Benjamaporn Mekrakseree, M.D.^6*, Kamolchanok Kulchutisin^7* and Weerapat Owattanapanich, M.D.^1*

¹Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
²Division of Hematology, Department of Internal Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
³Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand
⁴Division of Hematology, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand
⁵Chiang Rai Regional Hospital, Chiang Rai, Thailand
⁶Division of Hematology, Department of Medicine, Rajavithi Hospital, Bangkok, Thailand
⁷Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Smita Kayal, MD, DM^1*, Hasmukh Jain, MD, DM^2*, Lingaraj Nayak, MD, DM^2*, Jayashree Thorat, MD, DM^2*, Jina Bhattacharyya, MD, DM^3*, Damodar Das, MD, DNB^3*, Sewali Deka Talukdar, MD^3*, Dinesh Bhurani, MD, FRCPA^4*, Rayaz Ahmed, MD, DM⁴, Narendra Agrawal, MD, DM^4*, Dubashi Biswajit, MD, DNB, DM^1*, Prasanth Ganesan, MD, DM^1*, Chandran K. Nair, MD, DNB, DM^5*, Vineetha Raghavan, MD^5*, Manuprasad A, MD, DM^5*, Uday Kulkarni, MD, DM^6*, Sushil Selvarajan, MD, DM^6*, Jayachandran PK, MD, MRCP, DM^7*, Parathan Karunakaran, MD, DM^7*, Sadashivudu Gundeti, MD, DM⁸, Kundan Mishra, MD, DM, MNAMS^9*, Sharat Damodar, MBBS, MD, DM¹⁰, Bharath Ram S, MBBS, DNB¹¹, Atul Sharma, MD, DM^12*, Suvir Singh, DM^13*, M. Joseph John, MD, DM¹⁴, Gaurav Prakash, MD, DM^15*, Smitha Carol Saldanha, MD, DM^16*, Chepsy C Philip, MD, DM¹⁷, Prashant Mehta, MD, DM^18*, Thenmozhi Mani, PhD^19*, Om Prakash, MSc^19*, Marimuthu S^19*, Jeyaseelan Lakshmanan, PhD^19*, Manju Sengar, MD, DM ², Vikram Mathews, MD, DM⁶ and Rajan Kapoor, MD, DM^9*

¹Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry, India
²Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
³Department of Clinical Hematology, Gauhati Medical College & Hospital, Guwahati, India
⁴Department of Hemato-Oncology & BMT, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
⁵Department of Clinical Hematology and Medical Oncology, Malabar Cancer Centre, Thalassery, India
⁶Department of Haematology, Christian Medical College, Vellore, India
⁷Department of Medical Oncology, Cancer Institute (WIA), Chennai, India
⁸Department of Medical Oncology, Nizam's Institute of Medical Sciences, Hyderabad, India
⁹Department of Haematology, Army Hospital (Research & Referral), New Delhi, India
¹⁰Department of Hematology, Mazumdar Shaw Medical Center, Narayana Health City, Bangalore., India
¹¹Department of Hematology, Mazumdar Shaw Medical Center, Narayana Health City, Bangalore, India
¹²Department of Medical Oncology, Dr. B.R.A. IRCH, All India Institute of Medical Sciences (AIIMS), New Delhi, India
¹³Department of Clinical Haematology, Dayanand Medical College and Hospital, Ludhiana, India
¹⁴Department of Clinical Haematology and BMT, Christian Medical College & Hospital, Ludhiana, India
¹⁵Department of Clinical Hematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
¹⁶Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, India
¹⁷Department of Clinical Hematology, Believers Church Medical College Hospital, Tiruvalla, India
¹⁸Department of Medical Oncology and BMT, Asian Institute of Medical Sciences, Faridabad, India
¹⁹Department of Biostatistics, Christian Medical College, Vellore, India

Laura Simon^1*, Alexis Caulier^1,2*, Celine Berthon, MD, PhD^3*, Thomas Boyer, MD^2,4*, Véronique Harrivel, MD^4*, Magalie Joris, MD^1*, Amandine Charbonnier, MD^1*, Etienne Paubelle, MD^1*, Isabelle Leduc, MD^5*, Nicolas Duployez, PharmD, PhD^6*, Christophe Roumier, PharmD^6*, Claude Preudhomme, PharmD, PhD⁶, Stéphane Morisset^7*, Jean-Pierre Marolleau, MD, PhD^1,2 and Delphine Lebon, MD^1*

¹Service d’Hématologie Clinique et Thérapie cellulaire, Centre Hospitalier Universitaire d’Amiens, Amiens, France
²EA4666 – HEMATIM, CHU Amiens, Amiens, France
³Hematology Department, CHU Lille, Lille, France
⁴Laboratoire d'Hématologie, CHU Amiens, Amiens, France
⁵Service de médecine interne, CH Abbeville, Abbeville, France
⁶Laboratory of Hematology, CHU Lille, Lille, France
⁷Biostatistics consultant, Pérouges, France

Veit L Buecklein, MD^1,2*, Maximilian Warm^2*, Karsten Spiekermann^2,3, Christian Schmidt, MD^2*, Michael Unterhalt, MD, PhD^2*, Naval Daver, MD⁴ and Marion Subklewe, MD^1,5,6

¹Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany
²Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
³Experimental Leukemia and Lymphoma Research (ELLF), University Hospital, LMU Munich, Munich, Germany
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany
⁶Department of Medicine III (Hematology/Oncology), LMU University Hospital Munich, Muenchen, Germany

Tamer Hellou, MD^1*, Omri Cohen, MD, BS^2*, Abraham Avigdor, MD³, Avichai Shimoni, MD^4*, Mudi Misgav^5* and Jonathan Canaani, MD⁶

¹Sheba Medical Center, Tel Hashomer, Israel
²National Hemophilia Center, Sheba Medical Center, Tel Hashomer, Israel
³Chaim Sheba Medical Center, Ramat Gan, Israel
⁴Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat Gan, Israel
⁵National Hemophilia Center and Institute of Thrombosis & Hemostasis, Sheba Medical Center, Tel-Hashomer, Israel
⁶Hematology Division, Sheba Medical Center, Givatayim, Central, Israel

Hong Qu^1*, Yu Zhang^2*, Na Xu, MD, PhD^2* and Shuqin Cheng, Ph.D^3*

¹Department of Hematology, Nanfang Hospital, Southern Medical University, guangzhou, China
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Department of Hematology, Panyu Central Hospital, Guangzhou, China

Isla McKerrow Johnson, MD¹, Rimal Ilyas, MBBS^1*, Kristen McCullough, PharmD², Aref Al-Kali, MD², Hassan B. Alkhateeb, MD^2*, Kebede Begna, MD³, Abhishek A. Mangaonkar, MBBS², Mark R. Litzow, MD², William J. Hogan, MB, BCh², Mithun V. Shah, MD, PhD⁴, Mrinal M. M. Patnaik, MD², Animesh Pardanani, MBBS, PhD ², Ayalew Tefferi, MD² and Naseema Gangat, MBBS²

¹Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Divison of Hematology, Mayo Clinic, Rochester, MN
⁴Divison of Hematology, Mayo Clinic, Rochester

Anmol Baranwal, MBBS^1*, Mithun V. Shah, MD, PhD¹, Amit Barua, MD^2*, Aysun Senturk Yikilmaz, MD^3*, Rong He, MD⁴, David S. Viswanatha, MD⁵, Talha Badar, MD⁶, Bahga Katamesh^7*, Abhishek A. Mangaonkar, MBBS¹, Naseema Gangat, MBBS¹, Mrinal M. M. Patnaik, MD¹, Mark R. Litzow, MD¹, William J. Hogan, MB, BCh¹, Kebede Begna, MD⁸, Ayalew Tefferi, MD¹, Aref Al-Kali, MD¹ and Hassan B. Alkhateeb, MD^1*

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Cinic, Rochester
³Mayo Clinic, Rochester
⁴Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁵Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁶Division of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, FL
⁷Division of Hematology, Mayo Clinic, Rochester, CT
⁸Divison of Hematology, Mayo Clinic, Rochester, MN

Fahad Alkaabba, MBBS^1*, Matthew Williams, MD^1*, Elizabeth Corley, MD^2*, Hanan Alharthy, MBBS³, Kathryn A. F. Kline, MD, MPH³, Seung Tae Lee, MD, PhD³, Michael Kallen, MD^4*, Sandrine Niyongere, MD³, Vu H. Duong, MD, MS³, Maria R. Baer, MD³ and Moaath K. Mustafa Ali, MD, MPH^3,5

¹Department of Medicine, University of Maryland Medical Center, Baltimore, MD
²Weil-Cornell Medical Center, New York, NY
³University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD
⁴Department of Pathology, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD
⁵Leukemia Division, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH

Pierre Luc Mouchel, MD; PhD^1*, Sarah Bertoli, MD; PH.D^1*, Emilie Berard, MD^2*, Francois Vergez, DVM, PhD^3*, Jean-Baptiste Rieu, PharmD^4*, Isabelle Luquet, MD^5*, Laetitia Largeaud, PharmD^6*, Nathan Guiraud, PhD student^7*, Jean-Emmanuel Sarry, PhD^8*, Audrey Sarry, CRA^9*, Francoise Huguet, MD^10*, Suzanne Tavitian, MD^9* and Christian Recher, MD⁹

¹Service d'Hematologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
²Service d'Epidémiologie, CHU de Toulouse, Toulouse, France
³Laboratoire d'Hematologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse-Oncopole, TOULOUSE, France
⁴Laboratoire d'hématologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse Oncopole, TOULOUSE, FRA
⁵Laboratoire d'Hématologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
⁶Laboratoire d'hématologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse cedex9, France
⁷Centre de Recherches en Cancérologie de Toulouse (CRCT) - Team METAML, Inserm - Université Paul Sabatier - CNRS, Toulouse, France
⁸Centre de Recherches en Cancérologie de Toulouse - CRCT, Inserm - Université de Toulouse Paul Sabatier – CNRS, Toulouse, France
⁹Service d'Hématologie, CHU de Toulouse - Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
¹⁰Service d'Hematologie, CHU de Toulouse- Institut Universitaire de Cancérologie de Toulouse Oncopole, Toulouse, France

Julia Lee, PharmD^1*, Charlotte B Wagner, PharmD^1*, Stacy Prelewicz, PharmD^1*, Heena P Kurish, PharmD^2*, Rob Walchack, PharmD^3*, Danielle Cenin, PharmD^4*, Seema Patel, PharmD^4*, Mimi Lo, PharmD, BCPS, BCOP^5*, Danielle Schlafer, Pharm D, BCOP^6*, Belinda KT Li, PharmD^7*, R Donald Harvey, PharmD⁸, Bestis Wasef, PharmD^9*, Jian Ying, PhD^10* and Tibor Kovacsovics, MD¹¹

¹University of Utah Huntsman Cancer Institute, Salt Lake City, UT
²Department of Pharmacy, Cleveland Clinic, Cleveland, OH
³Cleveland Clinic Department of Pharmacy, Cleveland, OH
⁴Blood and Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁵Department of Pharmaceutical Services, University of California San Francisco, San Francisco, CA
⁶Emory University Hospital, Atlanta
⁷Emory Healthcare Winship Cancer Institute, Atlanta, GA
⁸Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
⁹Oregon Health and Science University Hospital, Portland, OR
¹⁰University of Utah School of Medicine, Salt Lake City, UT
¹¹Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT

Manju Sengar, MD, DM ¹, Hasmukh Jain, MD, DM^2*, Uday Prakash Kulkarni, MD^3*, Vasu Babu Goli^4*, Anu Korula, MD, DM^3*, Prasanna Samuel, MSc, PhD^5*, Sushil Selvarajan, MD, DM^3*, Lingaraj Nayak, MD, DM^6*, Aby Abraham, MD, DM^7*, Om Prakash, MSc^5*, Fouzia N., DM^8*, Saranya Kumaran^9*, Jayashree Thorat, MD, DM^10*, Bhausaheb Bagal, MD, DM^11*, Poonkuzhali Balasubramanian, MSc, PhD³, Dhanlaxmi Shetty^12*, Nikhil Patkar, MD^13*, Biju George, MD, DM¹⁴ and Vikram Mathews, MD, DM⁷

¹Department of Medical Oncology, Tata Memorial Centre Affiliated to Homi Bhabha National Institute, Mumbai, India
²Department of Medical Oncology, Tata Memorial Centre, Affiliated to Homi Bhabha National Institute, Mumbai, India
³Department of Haematology, Christian Medical College, Vellore, India
⁴Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India
⁵Department of Biostatistics, Christian Medical College, Vellore, India
⁶Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
⁷Department of Haematology, Christian Medical College, Vellore, Tamil Nadu, India
⁸Department of Haematology, Christian Medical College, Washington, DC
⁹Christian Medical Vellore, Vellore, India
¹⁰Department of Medical Oncology, Tata Memorial Centre, Affiliated to Homi Bhabha National Institute, Mumbai, Maharashtra, India
¹¹Department of Medical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
¹²Cytohenetics, Tata Memorial Centre, Affiliated to Homi Bhabha National Institute, Navi Mumbai, India
¹³Haematopathology Laboratory, Tata Memorial Hospital, Tata Memorial Centre, Affiliated to Homi Bhabha National Institute, Navi Mumbai, India
¹⁴Department of Haematology, Christian Medical College, Vellore, Tamilnadu, India

Jiayan Gu, PhD^1,2*, Jie Jin, M.D., Ph.D.^3,4,5 and Hongyan Tong, MD, PhD^3*

¹Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China, Hangzhou, AL, China
²Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang Province, Hangzhou 310003, China, Hangzhou, China
³Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China, Hangzhou, China
⁴Zhejiang Provincial Clinical Research Center for Hematological Disorders, Hangzhou, China
⁵Zhejiang Provincial Key Laboratory of Hematopoietic Malignancy, Zhejiang University, Hangzhou, Zhejiang, PR China, Hangzhou, China