Jason C Collins, PhD^1*, Nicholas Balanda^1*, Samuel J Magaziner^2*, Maya English^1*, Daniela Ospina Cardona^2*, Mrinal M. M. Patnaik, MD³, Benjamin Terrier, MD, PhD^4*, Olivier Kosmider, MD, PhD^5*, Achim Werner, PhD^6* and David B. Beck^7*

¹National Institutes of Health, Bethesda, MD
²New York University School of Medicine, New York, NY
³Division of Hematology, Mayo Clinic, Rochester, MN
⁴Service de Médecine interne, Assistance Publique des Hopitaux de Paris / Hôpital Cochin, Paris, FRA
⁵Assistance Publique Hôpitaux de Paris, Laboratoire d'hématologie, Hôpital Cochin, Institut Cochin, INSERM U1016, University Paris Descartes, Paris, France
⁶National Institutes of Heath, Bethesda, MD
⁷Center for Human Genetics and Genomics, New York University School of Medicine, New York, NY

Olisaemeka Ogbue¹, Tariq Kewan, MD^2*, Waled Bahaj^2*, Carmelo Gurnari, MD^2,3, Valeria Visconte, PhD⁴, Suresh Kumar Balasubramanian, MD⁵, Bhumika J. Patel, MD^6*, Alan Lichtin, MD⁶, Hetty E. Carraway, MD, MBA⁶ and Jaroslaw P. Maciejewski, MD, PhD, FACP²

¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Rocky River, OH
²Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
³Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy
⁴Taussig Cancer Institute, Cleveland, OH
⁵Wayne State University, Detroit, MI
⁶Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH

Simon Buatois^1*, Khaled Benkali^2*, Andrea Henrich^3*, Félix Jaminion^1*, Yuchen Zhang^4* and Alexandre Sostelly, PhD, MSc^1*

¹F. Hoffmann-La Roche Ltd, Basel, Switzerland
²Certara, Inc., Paris, France
³Pharmetheus, Uppsala, Sweden
⁴China Innovation Center of Roche, Shanghai, China

Christopher J. Patriquin, MD, MSc, FRCPC¹, Andrija Bogdanovic, MD, PhD, MSc^2*, Morag Griffin, FRCPath, MRCP^3*, Richard Kelly, BSc, MD^3*, Jaroslaw P. Maciejewski, MD, PhD, FACP⁴, Brian Mulherin, MD^5,6*, Regis Peffault De Latour^7,8*, Alexander Roeth, MD⁹, Veena Selvaratnam^10*, Jeffrey Szer, MBBS, FRACP¹¹, Jessica Savage, MD, MHS^12*, Regina Horneff, PhD^13*, Lisa Tan^13*, Michael Yeh, MD, MBA, MPH^14* and Jens Panse, MD^15,16

¹Hematology & Apheresis Medicine, University Health Network, Toronto General Hospital, Toronto, ON, Canada
²Clinic of Hematology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
³Department of Haematology, St James University Hospital, Leeds, United Kingdom
⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
⁵Hematology Oncology Of Indiana, Indianapolis, IN
⁶Ascension St. Vincent Carmel, Carmel, IN
⁷French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
⁸Assistance Publique–Hôpitaux de Paris, Saint-Louis Hospital, Université Paris Cité, Paris, France
⁹Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, Essen, Germany
¹⁰Department of Hematology, Ampang Hospital, Ampang, Malaysia
¹¹Department of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
¹²Apellis Pharmaceuticals, Waltham, MA
¹³Swedish Orphan Biovitrum AB, Stockholm, Sweden
¹⁴Apellis Pharmaceuticals, Inc., Waltham, MA
¹⁵Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany
¹⁶Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany

Audrey Le Floch-Ramondou, PhD^1*, Kirsten Nagashima^2*, Kaitlyn Gayvert^2*, Hao Pan^2*, Chandrashekhar Korgaonkar^2*, Hassan Shakil^2*, Erica Ullman^2*, Thomas Norton^2*, Lorah Perlee, PhD^3*, Andrew J. Murphy, PhD^1*, Matthew Sleeman^2* and Jamie Orengo^2*

¹Regeneron, Tarrytown, NY
²Regeneron, Tarrytown
³Regeneron Pharmaceuticals, Inc., Tarrytown, NY

Xiaoqing Liu^1*, Qiqiang Long^2*, Xi Chen^2*, Chun Qiao^3*, Guangsheng He^4*, Shengyun Lin^5* and Jianyong Li, MD^4,6

¹Hematology, the Second People's Hospital of Nanjing, Nanjing, China
²the Second People’s Hospital of Nanjing, Nanjing, China
³Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
⁴Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⁵The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China, Hangzhou, China
⁶Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China

Morag Griffin, FRCPath, MRCP^1*, Shreyans Gandhi^2*, Eden Hicks^3*, Deepak Jain, MD^3*, Richard Kelly, BSc, MD^4*, Talha Munir, MBBS, MRCP, FRCPath, PhD^5*, Petra Muus^6*, Masayo Ogawa, MD^3*, Roochi Trikha^2*, Ji Yu^3* and Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP⁷

¹St James's University Hospital, Sheffield, United Kingdom
²King’s College Hospital, National Institute for Health and Care Research/Wellcome King’s Clinical Research Facility, London, United Kingdom
³Alexion, AstraZeneca Rare Disease, Boston, MA
⁴Department of Haematology, St James University Hospital, Leeds, United Kingdom
⁵Consultant Haematologist, St James's Hospital, Leeds, United Kingdom
⁶St James’s University Hospital, Leeds, United Kingdom
⁷King’s College Hospital, National Institute for Health and Care Research/Wellcome King’s Clinical Research Facility, London, ENG, United Kingdom

Zoe McQuilten, MBBS, PhD^1,2*, Lucy C. Fox, MBBS^3,4, Vanessa Fox, BSc^5*, Stephane Heritier, PhD^4*, Tracey J Batt, FRACP, FRCPA, MBBS^6*, Piers Blombery, MBBS⁷, Jennifer Curnow, MBBS FRACP FRCPA PhD^8*, Alisa Higgins, PhD^4*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA⁹, Robin J Filshie, MBChB, PhD, FRACP, FRCPA¹⁰, Frank Firkin, MBBS^11*, Paul Lacaze, PhD^12*, Kylie D Mason, MBBS, MD, FRACP, FRCPA, PhD¹³, Tony Mills, MBBS^14*, Sushrut S. Patil^15*, Dominic Pepperell, MBBS^16*, William S Stevenson, MBBS, PhD, FRACP, FRCPA¹⁷, Jeffrey Szer, MBBS, FRACP¹⁸, Neil Waters, BSc^4*, Kate Wilson^19*, Stephen B Ting, MBBS, FRACP, FRCPA, PhD^20* and Erica M. Wood, MBBS, FRACP, FRCPA^21,22

¹Monash Haematology, Monash Health, Clayton, VIC, Australia
²Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia
³Peter MacCallum Cancer Centre, Melbourne, Australia
⁴Monash University, Melbourne, Australia
⁵Public Health and Preventative Medicine, Monash University, Melbourne, Australia
⁶Royal Hobart Hospital, Hobart, Australia
⁷Peter MacCallum Cancer Centre, Peter Maccallum Cancer Centre, East Melbourne, VIC, Australia
⁸Department of Haematology, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia
⁹Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia
¹⁰Department of Hematology, St. Vincent's Hospital Melbourne, Melbourne, VIC, Australia
¹¹St Vincent's Hospital, Melbourne, Australia
¹²Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
¹³Department of Medicine, University of Melbourne, Melbourne, Australia
¹⁴University of Queensland, Brisbane, Australia
¹⁵Alfred Hospital, Melbourne, AUS
¹⁶Department of Haematology, Fiona Stanley Hospital, Murdoch, Australia
¹⁷Department of Haematology, Royal North Shore Hospital, Sydney, NSW, Australia
¹⁸Department of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
¹⁹University of Sydney, Sydney, Australia
²⁰Department of Haematology, Eastern Health and Monash University, Melbourne, VIC, Australia
²¹Department of Clinical Haematology, Monash Health, Melbourne, VIC, Australia
²²Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Congwei Zhong^1*, Tong Chen^2*, Chunyan Liu^3*, Zonghong Shao⁴ and Rong Fu^5*

¹Tianjin Medical University General Hospital, Tianjin, China, AL, China
²Tianjin Medical University General Hospital, Tianjin, China
³Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China
⁴Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, China
⁵Department of hematology, Tianjin Medical University General Hospital, Tianjin, China

Hui Liu^1*, Wei Wang^2*, Lijie Zeng^1*, Zhaoyun Liu^1*, Liyan Li^1*, Zonghong Shao³ and Rong Fu^1*

¹Department of hematology, Tianjin Medical University General Hospital, Tianjin, China
²Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, China
³Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China

Morag Griffin, FRCPath, MRCP^1*, Richard Kelly, BSc, MD^1*, Dries Deeren, MD, PhD², Yeow Tee Goh, MBBS³, Eric Tse, MBBS, PhD, FRCP, FRCPath⁴, Kensuke Usuki, MD, PhD⁵, Raymond Wong, MBChB, MD⁶, Regina Horneff, PhD^7*, Lisa Tan^7*, Michael Yeh, MD, MBA, MPH^8*, Jessica Savage, MD, MHS^9* and Jeff Szer, MBBS, FRACP¹⁰

¹Department of Haematology, St James University Hospital, Leeds, United Kingdom
²Algemeen Ziekenhuis (AZ) Delta, Roeselare, Belgium
³Department of Hematology, Singapore General Hospital, Singapore, Singapore
⁴Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong
⁵Department of Hematology, NTT Medical Center Tokyo, Tokyo, Japan
⁶Sir YK Pao Centre for Cancer & Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Hong Kong
⁷Swedish Orphan Biovitrum AB, Stockholm, Sweden
⁸Apellis Pharmaceuticals Inc., Waltham, MA
⁹Apellis Pharmaceuticals, Waltham, MA
¹⁰Department of Clinical Haematology, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Melbourne, Australia

Xin Zhao, MD^*, Baohang Zhang^*, Jianping Li^*, Huihui Fan^*, Yuan Li^*, Wenrui Yang^*, Liping Jing, MD^*, Li Zhang^*, Kang Zhou^*, Youzhen Xiong^*, Lei Ye^*, Yingchang Mi, MD and Fengkui Zhang^*

Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, China

Alice Garnier, MD^1*, Amandine Le Bourgeois, MD^1*, Thierry Guillaume, MD, PhD^2*, Pierre Peterlin, MD^3*, Maxime Jullien, MD^4*, Marianne Coste-Burel, MD, PhD^5*, Marie C Bene, PharmD, DPhil^6,7* and Patrice Chevallier, MD^8,9

¹Hematology Department, Nantes University Hospital, Nantes, France
²Clinical Hematology Department, Nantes University Hospital, Nantes, France
³Clinical Hematology, Nantes University Hospital, Nantes, France
⁴Clinical Hematology, Nantes University Hospital, NANTES, France
⁵Virology, Nantes University Hospital, Nantes, France
⁶Hematology Biology, Nantes University Hospital, Nantes, France
⁷CHU Nantes, Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Nantes, France
⁸CRCI2NA, Integrated Research Center in Immunology and Oncology, Nantes University, Nantes, France
⁹Department of Clinical Hematology, Nantes University Hospital, Nantes, France