-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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627A.O2.6 627. Aggressive Lymphomas: Clinical and Epidemiological: Real World Evidence for Management of CNS Lymphoma and Post CAR T-cell relapse for aggressive B-cell NHL

Symposia: Aggressive Lymphomas: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Biological therapies, adult, epidemiology, Lymphomas, non-Hodgkin lymphoma, Bispecific Antibody Therapy, Clinical Practice (Health Services and Quality), Non-Biological therapies, Clinical Research, B Cell lymphoma, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Combination therapy, health outcomes research, Checkpoint Inhibitor, Diseases, real-world evidence, aggressive lymphoma, Therapies, Immunotherapy, registries, Lymphoid Malignancies, Adverse Events, Study Population, Human, Radiation Therapy
Sunday, December 11, 2022: 12:00 PM-1:30 PM
R02-R05 (Ernest N. Morial Convention Center)
Moderators:
Tarec Christoffer El-Galaly, MD, DSc, Department of Haematology, Aalborg University Hospital and Juan Pablo Alderuccio, MD, University of Miami Miller School of Medicine
Disclosures:
El-Galaly: Abbvie: Other: Teaching in 2021; Roche: Ended employment in the past 24 months. Alderuccio: ADC Therapeutics: Consultancy, Research Funding; Pyramid: Consultancy; Agios: Consultancy.
This session provides real world data on clinical features, treatment patterns, and outcomes for patients with aggressive B-cell NHL who are refractory to or relapse after CAR T–cell therapy. In addition, this session provides relevant population-based data to guide prognostication, staging, risk assessment, and treatment of CNS lymphoma.
12:00 PM

Federico Erbella1*, Emmanuel Bachy, MD, PhD2*, Guillaume Cartron, MD, PhD3*, Elodie Gat4*, Franck Morschhauser, MD5*, Benoit Tessoulin, MD6*, Olivier Tournilhac, MD, PhD7*, Choquet Sylvain, MD8*, François-Xavier Gros9*, Cristina Castilla-Llorente, MD10*, Arnaud Campidelli, MD11*, René-Olivier Casasnovas, MD, PhD12*, Louise Roulin13*, Pierre Bories, MD14*, Mohamad Mohty, MD PhD15, Martin Carre, MD16*, Steven Le Gouill, MD, PhD17, Roch Houot, MD, PhD18* and Roberta Di Blasi, MD, PhD19*

1Hemato-oncology departement, APHP, Saint-Louis Hospital, Paris, France
2Hematology Department, Hospices Civils de Lyon, Lyon, France
3Hematology Department, Montpellier University Hospital, Montpellier, France
4LYSARC, The Lymphoma Academic Research Organisation, Lyon Sud Hospital, PIERRE-BENITE, France
5Centre Hospitalier Régional Universitaire De Lille, Lille, FRA
6Hematology Department, Nantes University Hospital, Nantes, France
7Department of Hematology, University Hospital of Clermont-Ferrand, Clermont Auvergne University, Clermont-Ferrand, France
8Department of Clinical Haematology, Sorbonne Université, AP-HP, Pitié-Salpêtrière Hospital, Paris, France
9Hopital Du Haut-lévèQue, Pessac, FRA
10Department of hematology, Gustave Roussy Institute, Villejuif, France
11Hematology Department, University Hospital of Nancy, Vandoeuvre, France
12Hématologie Clinique, CHU Dijon Bourgogne, Dijon, France
13Hôpital Henri Mondor, Creteil, France
14Department of Hematology, Toulouse University Institute of Cancer, Toulouse, France
15Hematology Department, Hôpital Saint Antoine, Service d'Hématologie Thérapie Cellulaire, Paris, France
16Hematology, CHU Grenoble Alpes, La Tronche, France
17Institut Curie Comprehensive Cancer Center, Paris, France
18Hematology Department, CHU de Rennes, Rennes, France
19Department of Hematology, Assistance Publique Hôpitaux de Paris - Hopital Saint-Louis, University of Paris, PARIS, France

12:15 PM

Ajay Major, MD, MBA1, Jovian Yu, MD, MS2, Navika D. Shukla, MD2*, Rachel Treitman, BS3*, Manali K. Kamdar, MD3, Bradley M. Haverkos, MD, MS, MPH3, James Godfrey, MD4, Melissa A. Babcook, MD, PhD5, Timothy J. Voorhees, MD, MSc5, Sophie G Carlson, MD6*, Daria Gaut, MD6, Caspian Oliai, MD, MS6, Jason T. Romancik, MD7, Allison Winter, MD8, Brian T. Hill, MD, PhD9, Radhika Bansal, MBBS10*, Jose C. Villasboas, MD11, Imran A. Nizamuddin, MD12, Reem Karmali, MD, MSc13, Lindsey A. Fitzgerald, MD14, Deborah M. Stephens, DO15, Priyanka A. Pophali, MD16, Asaad Trabolsi, MD17*, Jonathan H. Schatz, MD18, Marie Hu, MD19, Veronika Bachanova, MD, PhD20, Michael J Slade, MD, MS21, Nathan Singh, MD21, Nausheen Ahmed, MBBS22, Joseph P. McGuirk, DO23, Michael R. Bishop, MD24,25, Peter A. Riedell, MD2,26* and Justin Kline, MD26,27

1The University of Chicago Comprehensive Cancer Center, Denver, CO
2The University of Chicago Comprehensive Cancer Center, Chicago, IL
3University of Colorado Cancer Center, Denver, CO
4City of Hope Comprehensive Cancer Center, Duarte, CA
5The Ohio State University James Comprehensive Cancer Center, Columbus, OH
6UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA
7Department of Hematology and Medical Oncology, Winship Cancer Institute at Emory University, Atlanta, GA
8Taussig Cancer Institute at Cleveland Clinic, Cleveland, OH
9Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
10Division of Hematology, Mayo Clinic, Rochester, MN
11Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
12Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL
13Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL
14Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT
15Huntsman Cancer Institute, Salt Lake City, UT
16University of Wisconsin Carbone Cancer Center, Madison, WI
17University of Miami Sylvester Comprehensive Cancer Center, Miami, FL
18University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL
19Masonic Cancer Center at the University of Minnesota, Minneapolis, MN
20Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
21Alvin J. Siteman Cancer Center at Washington University School of Medicine, Saint Louis, MO
22The University of Kansas Cancer Center, Overland Park, KS
23Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Kansas City, KS
24Comprehensive Cancer Center, University of Chicago Medicine, Chicago, IL
25The David and Etta Jonas Center for Cellular Therapy, University of Chicago, Chicago, IL
26The David and Etta Jonas Center for Cellular Therapy at The University of Chicago Medicine, Chicago, IL
27Department of Medicine Section of Hematology/Oncology, University of Chicago Medicine, Chicago, IL

12:30 PM

Waleed Alduaij, MD PhD1,2, Aixiang Jiang, MSc2,3*, Diego Villa, MD2,4, Brett Collinge2,3*, Susana Ben-Neriah, MSc2*, Merrill Boyle, BSc2*, Barbara Meissner2*, Laura K Hilton, PhD2*, Pedro Farinha, MD, PhD2,3*, Graham W Slack, MD, PhD3*, Jeffrey W. Craig, MD, PhD2,3*, Alina S. Gerrie, MD, MPH, FRCPC2,4, Ciara L. Freeman, MSc, FRCPath, MBBChir, MRCP2,5, Andrew J. Mungall, PhD2,6*, Christian Steidl2,3*, Laurie H. Sehn, MD, MPH2,4, David W. Scott, PhD, MD, FRACP, FRCPA2,4 and Kerry J. Savage, MD, MSc, FRCPC2,4

1UBC Clinician Investigator Program, University of British Columbia, Vancouver, BC, Canada
2Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
3Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
4Division of Medical Oncology, University of British Columbia, Vancouver, BC, Canada
5Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
6Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada

12:45 PM

Jelena Jelicic1*, Dennis Lund Hansen2*, Sarah Sand Carlsen3*, Michael Thorsgaard4*, Ditte Hersby5*, Karina Kannik6*, Amalie Emilie Munksgaard7*, Thomas S. Larsen, MD, PhD8* and Karen Juul-Jensen9*

1Department of Hematology, Odense University Hospital, Odense, AL, Denmark
2Hematology, Odense University Hospital, Odense, Denmark
3Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
4Department of Hematology, Vejle Regional Hospital, Vejle, Denmark
5Department of Hematology, Herlev University Hospital, Copenhagen, Denmark
6Department of Hematology, Aalborg University Hospital, Aalborg, Denmark
7Department of Hematology, Zeeland University Hospital, Roskilde, Roskilde, Denmark
8Department of Haematology, Odense University Hospital, Odense, Denmark
9Department of Hematology, Odense University Hospital, Odense, Denmark

1:00 PM

Kathryn R. Tringale, MD, MAS1*, Joachim Yahalom, MD1, Michael Scordo, MD2, Gustav Y Cederquist1*, Behroze Vachha, MD, PhD3*, Lauren Schaff, MD4*, Carla Hajj, MD1*, Harper Hubbeling, MD1, Zhigang Zhang, PhD5*, Charlie White, MS6*, Christian Grommes, MD7 and Brandon S. Imber, MD1

1Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
2Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center/New York, New York, NY
3Department of Radiology, Memorial Sloan Kettering Cancer Center, New York
4Neurology, Memorial Sloan Kettering Cancer Center, New York, NY
5Memorial Sloan Kettering Cancer Center, New York, NY
6Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
7Department of Medicine, Neuro-Oncology Service, Memorial Sloan Kettering Cancer, New York, NY

1:15 PM

Shihua Zhao1*, Yao Liu2*, Zunmin Zhu, MD3*, Jianxia He4*, Lihong Liu5*, Xiaobo Wang6*, Yuxia Zhao7*, Chongling Hu8*, Xiaoli Yuan9*, Sijun Bai10*, Ye Geng4* and Wenrong Huang11*

1Department of Hematology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, China
2Department of Hematology/Oncology, Affiliated Cancer Hospital of Chongqing University, Chongqing, China
3Department of Hematology, Henan Provincial People's Hospital, Zhengzhou, China
4Shanxi Provincial People's Hospital, Taiyuan, China
5Department of Hematology, The Fourth Hospital of Hebei Medical University, Hebei, China
6The Second Hospital of Dalian Medical University, Dalian, China
7Inner Mongolia Xingan League Pepple's Hospital, Taiyuan, China
8Chongqing University Cancer Hospital, Chongqing, China
9Department of Hematology, Henan Provincial People's Hospital, Zhengzhou, AL, China
10Shanxi Provincial People's Hospital, Taiyuan City, China
11the Fifth Medical Center of Chinese PLA General Hospital, Beijing, China

*signifies non-member of ASH