Robert Palmason^1,2,3*, Oscar Berlanga, PhD^4*, Jon Kristinn Sigurdsson^1*, Sæmundur Rögnvaldsson, MD^5,6*, Sigrun Thorsteinsdottir, MD, PhD^1,7, Sara Ekberg, PhD^8*, Michael Crowther, PhD^8*, Marina Levy^1*, Elin Ruth Reed^1*, Jon Þórir Oskarsson, MSc^9*, Gudrun Asta Sigurdardottir^1*, Brynjar Vidarsson, MD⁶, Pall Torfi Onundarson, MD⁶, Bjarni Agnar Agnarsson, MD^6*, Margret Sigurdardottir, MD^6*, Ingunn Thorsteinsdottir, MD, PhD^6*, Signy Vala Sveinsdottir, MD PhD^6*, Fridbjorn Sigurdsson, MD^10*, Isleifur Olafsson, MD, PhD^6*, Asdis Rosa Thordardottir^1*, Elias Eythorsson, MD, PhD^11*, Asbjorn Jonsson, MD^10*, Runolfur Palsson, MD^6*, Olafur Skuli Indridason, MD, MHS^6*, Thor Aspelund, PhD^1*, Gauti Gislason^1*, Andri Olafsson^1*, Ingigerdur Solveig Sverrisdottir, MD, BSc^1*, Hlif Steingrimsdottir, MD^6*, Thorir Einarsson Long, MD, PhD^3,12*, Malin Hultcrantz, MD, PhD¹³, Ola Landgren, MD¹⁴, Stephen Harding, PhD¹⁵, Brian G.M. Durie, MD¹⁶, Thorvardur Jon Love, MD, PhD^1* and Sigurdur Y Kristinsson, MD, PhD^1,6

¹Faculty of Medicine, University of Iceland, Reykjavik, Iceland
²Landspitali - The National University Hospital of Iceland, LUND, Sweden
³Skåne University Hospital, Lund, Sweden
⁴The Binding Site Group Ltd, Birmingham, United Kingdom
⁵Faculty of Medicine, University of Iceland, Reykjavík, Iceland
⁶Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland
⁷Department of Hematology, Rigshospitalet, København, Copenhagen, Denmark
⁸Red Door Analytics AB, Stockholm, Sweden
⁹Faculty of Medicine, University of Iceland, Reykjavik, Reykjavik, Iceland
¹⁰Akureyri Hospital, Akureyri, Iceland
¹¹Landspitali - The National University Hospital of Iceland, Reykjavík, Iceland
¹²Faculty of Medicine, University of Iceland, Reykjavik, AL, Iceland
¹³Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁴Myeloma Division, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
¹⁵The Binding Site Inc., Birmingham, United Kingdom
¹⁶Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Outpatient Cancer Center, Los Angeles, CA

Elias K Mai, MD^1*, Stefanie Huhn, PhD^2*, Kaya Miah^3*, Alexandra M Poos, PhD^2*, Christof Scheid⁴, Katja C. Weisel, MD⁵, Uta Bertsch, MD^1,6*, Markus Munder^7*, Oscar Berlanga, PhD^8*, Dirk Hose, MD, PhD⁹, Anja Seckinger, MD¹⁰, Anna Jauch, PhD^11*, Igor Wolfgang Blau, MD^12*, Mathias Haenel, MD^13*, Hans Salwender, M.D.^14*, Axel Benner^15*, Marc S Raab, MD^1*, Hartmut Goldschmidt, MD^1,16 and Niels Weinhold, PhD^1*

¹Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany
²Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
³Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁴Department I of Internal Medicine and Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany
⁵Department of Oncology, Hematology and BMT, University Medical Center of Hamburg-Eppendorf, Hamburg, Germany
⁶National Center for Tumor Diseases (NCT), Heidelberg, Germany
⁷Department of Hematology, Medical Oncology, and Pneumology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
⁸The Binding Site Group Ltd, Birmingham, United Kingdom
⁹Department of Hematology and Immunology, Myeloma Center Brussels, Vrije Universiteit Brussel, Brussels, Belgium
¹⁰Department of Hematology and Immunology, Vrije Universiteit Brussel, Brussels, Belgium
¹¹Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany
¹²Department of BMT, Clinic of Hematology, Oncology and Tumorimmunology, University Medicine Berlin, Berlin, Germany
¹³Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
¹⁴Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
¹⁵Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany
¹⁶National Center for Tumor Diseases, Heidelberg, Germany

Sunil Lakhwani^1*, María Victoria Mateos, MD, PhD², Joaquín Martínez-López, MD, PhD^3*, Bruno Paiva^4*, Laura Rosinol Dachs^5*, Rafael Martínez, M.D.^6*, Albert Oriol^7*, Joan Bargay^8*, Yolanda Gonzalez-Montes, MD^9*, Mercedes Gironella, MD^10*, Cristina Encinas, MD^11*, Jesus Martin, MD^12*, Isidro Jarque^13*, Miquel Granell^14*, Eugenia Abella, PhD^15*, Aránzazu García Mateo, PhD^16*, José Ángel Hernández-Rivas^17*, Elena Ramila, MD^18*, Isabel Krsnik, MD, PhD^19*, Luis Felipe Casado Montero, MD²⁰, Felipe De Arriba, PhD^21*, Luis Palomera, MD, PhD^22*, Antonia Sampol, MD²³, Jose Maria Moraleda, MD, PhD^24*, Maria Casanova, MD^25*, Pilar Delgado, MD^26*, Ana Lafuente, MD^27*, Elena Amutio, MD^28*, Aurelio Lopez Martínez, MD^29*, Albert Altés^30*, M. Ángeles Ruíz^31*, Lucia Lopez-Anglada, PhD^32*, Joan Bladé Creixenti, MD, PhD⁵, Juan-José Lahuerta, MD, PhD^33*, Jesús San-Miguel, MD, PhD⁴ and Miguel-Teodoro Hernández, MD, PhD^34*

¹Hospital Universitario de Canarias, Universidad de La Laguna, Sta.Cruz Tenerife, Spain
²Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigación del Cancer (IBMCC-USAL, CSIC), Salamanca, Spain
³Hospital Univ. 12 de Octubre, Complutense University, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain
⁴Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA, Pamplona, Spain
⁵Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
⁶Hospital Universitario San Carlos, Madrid, Spain
⁷Institut Català d’Oncologia and Institut Josep Carreras, Hospital Germans Trias i Pujol, Badalona, Spain
⁸Hospital Son Llàtzer, Palma de Mallorca, Spain
⁹Hospital Universitari Dr. Josep Trueta, ICO Girona, Girona, Spain
¹⁰Hospital Universitari Vall d’Hebron, Barcelona, Spain
¹¹Hospital Gregorio Marañón, Madrid, Spain
¹²Hospital Universitario V. Rocio, Sevilla, Spain
¹³Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Spain
¹⁴Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
¹⁵Hospital del Mar, Barcelona, Barcelona, ESP
¹⁶Hospital General de Segovia, Segovia, Spain
¹⁷Hematology Department, Hospital Universitario Infanta Leonor, Madrid, Spain
¹⁸Hospital Parc Tauli, Sabadell, Barcelona, Spain
¹⁹Hospital Universitario Puerta de Hierro, Madrid, Spain
²⁰Hospital General Universitario de Toledo, Toledo, Spain
²¹Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
²²Hospital Clínico U. "Lozano Blesa". Instituto Investigación Sanitaria Aragón, Zaragoza, Spain
²³Hospital Universitario Son Espases, Palma de Mallorca, Spain
²⁴Hospital Clínico Universitario Virgen de la Arrixaca. IMIB-Arrixaca. University of Murcia, Murcia, Spain
²⁵Hospital Costa del Sol Marbella, Marbella, Spain
²⁶Hospital Miguel Servet, Zaragoza, Spain
²⁷Hospital Universitario del Tajo, Toledo, Spain
²⁸Hospital Universitario Cruces., Bilbao, Spain
²⁹Hospital Arnau de Vilanova, Lleida, Spain
³⁰Hospital Althaia, Xarxa Assistencial de Manresa, Manresa, Spain
³¹Hospital Francesc de Borja, Valencia, Spain
³²Hospital 12 de Octubre, Madrid, Spain
³³Hospital Universitario 12 de Octubre; Instituto de Investigación Sanitaria Hospital Universitario 12 de Octubre i+12,H12O-CNIO Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain
³⁴Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Spain

Jean-Sébastien Claveau, MD^1*, David L Murray, MD, PhD^2*, Angela Dispenzieri, MD³, Prashant Kapoor, MD³, Moritz Binder, MD, MPH³, Francis K. Buadi, MB³, David Dingli, MD, PhD³, Amie Fonder, PA-C^3*, Morie A. Gertz, MD, MACP³, Wilson I. Gonsalves, MD³, Suzanne R. Hayman, MD³, Miriam A. Hobbs, APRN, CNP, DNP^3*, Yi L. Hwa, NP³, Taxiarchis Kourelis, MD³, Martha Q. Lacy, MD⁴, Nelson Leung, MD⁵, Yi Lin, MD, PhD⁶, Rahma M Warsame, MD⁶, Robert A. Kyle, MD⁷, S. Vincent Rajkumar, MD^3* and Shaji K Kumar, MD⁶

¹Division of hematology, Mayo Clinic, Rochester, MN
²Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
³Division of Hematology, Mayo Clinic, Rochester, MN
⁴Division of Hematology, Mayo Clinic Rochester, Rochester, MN
⁵Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN
⁶Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
⁷Division of Hematology, Mayo Clinic, Stabile 6-28, Rochester, MN

Somayya Noori, PhD^1*, Charissa Wijnands, MSc^2*, Pieter Langerhorst^3*, Simon Nadal^4*, Vincent Bonifay^4*, Christoph Stingl^5*, Cyrille Touzeau^6*, Theo Luider, PhD^7*, Thomas Dejoie^8*, Johannes Jacobs^2* and Martijn Vanduijn, PhD^7*

¹Erasmus MC, Rotterdam, AL, Netherlands
²Radboud University Medical Center, Nijmegen, Netherlands
³Radboudumc, Nijmegen, Netherlands
⁴Sebia, Lisses, France
⁵Erasmus Medical Center, Rotterdam, Netherlands
⁶University Hospital Hôtel Dieu, Nantes Cedex 1, FRA
⁷Erasmus MC, Rotterdam, Netherlands
⁸university hospital, Nantes, France

Joshua Bomsztyk^1*, Sriram Ravichandran, MBBS, MRCP, FRCPath^2*, Hannah Victoria Giles, FRCPath, MRCP^3*, Oscar Berlanga, PhD^4*, Stephen Harding, PhD⁵, Jahanzaib Khwaja^6*, Shameem Mahmood, MD^7,8*, Brendan Wisniowski, MD^7,9*, Oliver C Cohen, MBBS, BSc, FRCPath^10*, Darren Foard^11*, Janet Gilbertson^12*, Ana Martinez De Azcona Naharro^12*, Lucia Venneri^12*, Carol Whelan^10*, Marianna Fontana^12*, Philip N Hawkins, MD PhD^13*, Julian D Gillmore^13*, Helen J Lachmann^13*, Guy Pratt, MD FRCP FRCPath^14,15* and Ashutosh D. Wechalekar, MD^9,16

¹Royal Free Hospital, National Amyloid Centre, London, United Kingdom
²National Amyloidosis Centre, Royal Free Hospital, London, West Bengal, United Kingdom
³University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, United Kingdom
⁴The Binding Site Group Ltd, Birmingham, United Kingdom
⁵The Binding Site Inc., Birmingham, United Kingdom
⁶Department of Haematology, University College London Hospital NHS Foundation Trust, London, United Kingdom
⁷Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
⁸Haematology, National Amyloidosis Centre, London, United Kingdom
⁹National Amyloidosis Centre, London, United Kingdom
¹⁰National Amyloidosis Centre, Royal Free Hospital, London, United Kingdom
¹¹National Amyloidosis Centre, National Amyloidosis Centre, Royal Free Hospital, London, United Kingdom
¹²National Amyloid Centre, London, United Kingdom
¹³Royal Free Hospital, National Amyloidosis Centre, London, United Kingdom
¹⁴University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
¹⁵School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
¹⁶University College London Hospitals NHS Foundation Trust, London, United Kingdom