Laura Notarfranchi^1*, Anastasiia Zherniakova^2*, Marta Lasa, PhD^2*, Noemi Puig, MD, PhD³, María Teresa Cedena, MD, PhD^4*, Joaquin Martinez-Lopez, MD PhD^5*, María José Calasanz, PhD^2*, Diego Alignani, PhD^2*, Leire Burgos^2*, Irene Manrique^2*, Yi-Ju Huang^6*, Jochen Fracowiak^6*, Clara Gomez^7*, Felipe De Arriba, PhD^8*, Paula Rodríguez-Otero, MD, PhD^9*, Luis Palomera, MD, PhD^10*, Anna Sureda¹¹, Maria Esther Clavero Sanchez^12*, Miguel Angel Alvarez^13*, Angela Ibanez Garcia^14*, Miguel-Teodoro Hernández, MD, PhD^15*, Albert Perez^16*, Ana Pilar Gonzalez, PhD^17*, Enrique M. Ocio¹⁸, Juan Flores-Montero^3*, Alberto Orfao, MD, PhD¹⁹, Juan Jose Lahuerta, MD, PhD^4*, María-Victoria Mateos, MD, PhD³, Laura Rosiñol, MD, PhD^20*, Joan Bladé Creixenti, MD, PhD²⁰, Jesús San-Miguel, MD, PhD²¹ and Bruno Paiva^2*

¹Department of Medicine and Surgery, University of Parma, Parma, Italy
²Centro de Investigación Médica Aplicada, University of Navarra, Pamplona, Spain
³University Hospital of Salamanca, Salamanca, Spain
⁴Hospital Universitario 12 de Octubre, CNIO, Madrid, Spain
⁵H12O-CNIO Hematological Malignancies Group, Clinical Research Unit. CNIO, Madrid, Spain
⁶Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany
⁷Hospital Universitario de Galdakao, Galdakano,, Spain
⁸Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
⁹Clínica Universidad de Navarra, Navarra, CCUN, CIMA, IDISNA, CIBER-ONC, Pamplona, Spain
¹⁰Hospital Clínico U. "Lozano Blesa". Instituto Investigación Sanitaria Aragón, Zaragoza, Spain
¹¹Institut Català d'Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL). Universitat de Barcelona, Barcelona, Spain
¹²Hematology, Hospital Virgen de las Nieves, Granada, ESP
¹³Servicio de Hematología, Instituto Maimónides de Investigación Biomédica de Córdoba IMIBIC/Hospital Universitario Reina Sofía, Cordoba, ESP
¹⁴Hematology Department, Complejo Hospitalario Universitario de Albacete, Albacete, ESP
¹⁵Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
¹⁶Hematology Department, Son Espases University Hospital, Palma, CA, Spain
¹⁷Hospital Central de Asturias, Oviedo, Spain
¹⁸Hospital Universitario Marqués de Valdecilla (IDIVAL), Santander, Spain, Santander, Spain
¹⁹University Hospital of Salamanca, Salamanca, Salamanca, Spain
²⁰Amyloidosis and Multiple Myeloma Unit, Department of Hematology, IDIBAPS, Hospital Clínic, Barcelona, Spain
²¹Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA, Pamplona, Spain

Noemi Puig, MD, PhD¹, Cristina Agulló^1*, Teresa Contreras Sanfeliciano^2*, Bruno Paiva^3*, María Teresa Cedena, MD, PhD^4*, Laura Rosinol Dachs^5*, Ramon Garcia-Sanz⁶, Joaquín Martínez-López, MD, PhD^7*, Albert Oriol^8*, María Jesús Blanchard, MD^9*, Rafael Rios, MD, PhD^10*, Jesus Martin, MD^11*, Anna Sureda¹², Miguel Hernández^13*, Javier de la Rubia, MD^14*, Jose Maria Moraleda, MD, PhD^15*, Felipe De Arriba, PhD^16*, Luis Palomera, MD, PhD^17*, Belén Iñigo, MD^18*, Joan Bargay^19*, Joan Bladé Creixenti, MD, PhD^20,21,22,23, Jesús San-Miguel, MD, PhD²⁴, Juan Jose Lahuerta, MD, PhD^4* and María-Victoria Mateos, MD, PhD¹

¹University Hospital of Salamanca, Salamanca, Spain
²Servicio Análisis Clínicos y Bioquímica Clínica del Complejo Asistencial Salamanca, Complejo Asistencial Salamanca, Salamanca, Spain
³Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC number CB16/12/00369, Pamplona, Spain
⁴Hospital Universitario 12 de Octubre, CNIO, Madrid, Spain
⁵Hospital Clinic i Provincial, Barcelona, Spain
⁶Hospital Universitario de Salamanca (HUS/IBSAL), CIBERONC and Center for Cancer Research-IBMCC (USAL-CSIC), Salamanca, Spain
⁷Haematological Malignancies Clinical Research Unit, Hospital 12 de Octubre Universidad Complutense, CNIO, CIBERONC, Madrid, Spain
⁸Institut Català d’Oncologia and Institut Josep Carreras. Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
⁹Hematology Service, Hospital Universitario Ramón y Cajal, Madrid, Spain
¹⁰Hospital Universitario Puerta de Hierro, Madrid, Spain
¹¹Hospital Universitario V. Rocio, Sevilla, Spain
¹²Institut Català d'Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL). Universitat de Barcelona, Barcelona, Spain
¹³Hospital Universitario de Canarias, Santa Cruz de Tenerife, La Laguna, ESP
¹⁴Hematology Service Hospital La Fe and School of Medicine and Dentistry, Catholic University of Valencia, Valencia, Spain
¹⁵Department of Hematology, IMIB-Virgen de la Arrixaca University Hospital. University of Murcia, Murcia, Spain
¹⁶Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
¹⁷Hospital Clínico U. "Lozano Blesa". Instituto Investigación Sanitaria Aragón, Zaragoza, Spain
¹⁸Hematology, Hospital Universitario Clínico San Carlos, Madrid, Spain
¹⁹Hospital Universitario Son Llatzer, Institut d’ investigacio Illes Balears (IdISBa), Palma de Mallorca, Spain
²⁰Hospital Clinic de Barcelona, IDIBAPS, Barcelona, Spain
²¹HARMONY, European Network, Spain
²²Hospital Clinic, Barcelona, Barcelona, ESP
²³Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
²⁴Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA, Pamplona, Spain

Sunil Lakhwani^1*, Laura Rosinol Dachs^2*, Noemi Puig, MD, PhD³, Miguel Angel Pico Picos, MD^4*, Laura Medina-González, MD^4*, Joaquín Martínez-López, MD, PhD^5*, Bruno Paiva^6*, Albert Oriol^7*, Rafael Rios, MD, PhD^8*, María Jesús Blanchard, MD^9*, Isidro Jarque^10*, Joan Bargay^11*, Jose Maria Moraleda, MD, PhD^12*, Estrella Carrillo-Cruz, MD^13*, Anna Sureda¹⁴, Isabel Krsnik, MD, PhD^8*, Esther González Garcia, MD^15*, Luis Felipe Casado Montero, MD¹⁶, Josep M Marti, MD^17*, Cristina Encinas, MD^18*, Felipe De Arriba, PhD^19*, Luis Palomera, MD, PhD^20*, Antonia Sampol, MD²¹, Yolanda Gonzalez-Montes, MD^22*, Cristina Motllo^23*, Javier De La Cruz^24*, Rafael Alonso Fernández, MD^25*, María-Victoria Mateos, MD, PhD²⁶, Joan Bladé Creixenti, MD, PhD², Juan-José Lahuerta, MD, PhD^27*, Jesús San-Miguel, MD, PhD⁶ and Miguel-Teodoro Hernández, MD, PhD^28*

¹Hospital Universitario de Canarias, Universidad de La Laguna, Sta.Cruz Tenerife, Spain
²Amyloidosis and Myeloma Unit, Hospital Clínic, Barcelona, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
³Hospital Universitario de Salamanca Hematología. Instituto de investigación biomédica de Salamanca (IBSAL), Salamanca, Spain
⁴Hospital Universitario de Canarias, La Laguna, Spain
⁵Hospital Univ. 12 de Octubre, Complutense University, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain
⁶Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA, Pamplona, Spain
⁷Institut Català d’Oncologia and Institut Josep Carreras, Hospital Germans Trias i Pujol, Badalona, Spain
⁸Hospital Universitario Puerta de Hierro, Madrid, Spain
⁹Hematology Service, Hospital Universitario Ramón y Cajal, Madrid, Spain
¹⁰Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Spain
¹¹Hospital Son Llàtzer, Palma de Mallorca, Spain
¹²Hospital Clínico Universitario Virgen de la Arrixaca. IMIB-Arrixaca. University of Murcia, Murcia, Spain
¹³Hospital Universitario Vírgen del Rocío, Sevilla, Spain
¹⁴Institut Català d'Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL). Universitat de Barcelona, Barcelona, Spain
¹⁵Hospital Universitario de Cabueñes, Gijón, Spain
¹⁶Hospital General Universitario de Toledo, Toledo, Spain
¹⁷Hospital Universitari Mútua de Terrassa, Terrassa, Spain
¹⁸Hospital Gregorio Marañón, Madrid, Spain
¹⁹Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
²⁰Hospital Clínico U. "Lozano Blesa". Instituto Investigación Sanitaria Aragón, Zaragoza, Spain
²¹Hospital Universitario Son Espases, Palma de Mallorca, Spain
²²Hospital Universitari Dr. Josep Trueta, ICO Girona, Girona, Spain
²³Hospital Althaia, Xarxa Assistencial de Manresa, Manresa, Spain
²⁴Hospital Universitario 12 De Octubre, Instituto De Investigación Sanitaria, Madrid, Spain
²⁵Translational Hematology group, Hospital Universitrio 12 de Octubre-CNIO, Madrid, Spain
²⁶Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Centro de Investigación del Cancer (IBMCC-USAL, CSIC) (IBSAL), Salamanca, Spain
²⁷Hospital Universitario 12 de Octubre; Instituto de Investigación Sanitaria Hospital Universitario 12 de Octubre i+12,H12O-CNIO Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain
²⁸Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Spain

Bruno Paiva^1*, Irene Manrique^2*, Julie A Rytlewski, PhD^3*, Timothy B. Campbell, MD, PhD**³, Christian Kazanecki^4*, Nathan Martin, PhD^3*, Shari M. Kaiser, PhD^3*, Larry D. Anderson Jr., MD, PhD⁵, Jesus Berdeja, MD⁶, Sagar Lonial, MD⁷, Noopur Raje, MD⁸, Yi Lin, MD, PhD⁹, Philippe Moreau, MD^10*, Jesús San-Miguel, MD, PhD¹¹ and Nikhil C Munshi, MD, PhD¹²

¹Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC number CB16/12/00369, Pamplona, Spain
²Centro de Investigación Médica Aplicada, University of Navarra, Pamplona, Spain
³Bristol Myers Squibb, Princeton, NJ
⁴Bristol Myers Squibb, Princeton
⁵Myeloma, Waldenstrom’s and Amyloidosis Program, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁶Sarah Cannon Research Institute, Nashville, TN
⁷Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
⁸Mass General Hospital Cancer Center, Boston, MA
⁹Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
¹⁰Hematology Department, University Hospital Hôtel-Dieu, Nantes, France
¹¹Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA, Pamplona, Spain
¹²Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA

Mehmet K. Samur, PhD¹, Nathan Martin, PhD^2*, Ethan Thompson, PhD^3*, Mariateresa Fulciniti, PhD¹, Anil Aktas-Samur, PhD^4*, Shari Kaiser, PhD^2* and Nikhil C Munshi, MD, PhD⁵

¹Dana-Farber Cancer Institute, Boston, MA
²Bristol Myers Squibb, Princeton, NJ
³Informatics and Predictive Sciences, Bristol Myers Squibb, Seattle, WA
⁴Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
⁵Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA

Ben A. Derman, MD¹, Ajay Major, MD, MBA², Sarah Major, PA-C, MMS, MPH^1*, Brittany D. Wolfe, MMS, PA-C^1*, Martha Gorski, MSN, APN, FNP-C^1*, Jennifer H. Cooperrider, MD¹, Evangelia Andreatos, BS^1*, Ken Jiang^1*, Karson Buckley^1*, Amanda McIver^1*, Andrew Stefka, MS^1* and Andrzej Jakubowiak, MD, PhD¹

¹Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL
²University of Colorado School of Medicine, Denver, CO