Eric Padron, MD¹, Sara M Tinsley-Vance, PhD, ANP², Amy E. DeZern, MD³, Hetty E. Carraway, MD, MBA⁴, Marlise R. Luskin, MD⁵, Gail J. Roboz, MD⁶, Onyee Chan, MD², Meagan Horton^2*, Aaron T. Gerds, MD, MS⁷, David A. Sallman, MD¹, Andrew Kuykendall, MD⁸, David Steensma, MD^9*, Maria E Balasis^2*, Jeffrey E. Lancet, MD², Mikkael A. Sekeres, MD¹⁰ and Rami S. Komrokji²

¹Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
²Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
⁴Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
⁵Dana-Farber Cancer Institute, Boston, MA
⁶Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
⁷Department of Hematology and Medical Oncology,, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁸Department of Malignant Hematology, H. Lee Mofitt Cancer Center, Tampa, FL
⁹Novartis Institutes for BioMedical Research, Cambridge, MA
¹⁰University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL

Yu-Hung Wang, MD^1,2*, Chi-Yuan Yao, MD^1,3, Chien-Chin Lin, MD, PhD^1,3*, Kristian Gurashi^4*, Fabio Amaral, PhD^5*, Andres Jerez^6,7*, Tim C.P Somervaille, PhD FRCP FRCPath^5,8, Hsin-An Hou, MD, PhD¹, Wen-Chien Chou, MD, PhD^1,3, Kiran Batta, PhD^9*, Hwei-Fang Tien, MD, PhD¹ and Daniel H Wiseman, PhD, MB, ChB, MRCP, FRCPath^2,10*

¹Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
²Division of Cancer Sciences, The University of Manchester, Manchester, United Kingdom
³Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan
⁴University of Manchester, Manchester, United Kingdom
⁵Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⁶Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁷Hematology and Medical Oncology Department, Hospital Morales Meseguer, IMIB, Murcia, Spain, MURCIA, Spain
⁸Haematology Department, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
⁹Division of Cancer Sciences, The University of Manchester, Manchester, ENG, United Kingdom
¹⁰Haematology, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom

Uwe Platzbecker, MD¹, Rami S. Komrokji, MD², Pierre Fenaux³, Mikkael A. Sekeres, MD⁴, Michael Robert Savona^5*, Yazan F. Madanat, MD⁶, Koen Van Eygen, MD^7*, Azra Raza, MD^8,9, Ulrich Germing^10*, Laurie Sherman, BSN¹¹, Tymara Berry, MD^12*, Souria Dougherty, BS, MBA^12*, Sheetal Shah^12*, Libo Sun, PhD^12*, Ying Wan, PhD^11*, Fei Huang, PhD^12*, Annat Ikin^12*, Faye Feller, MD¹¹, Amer M. Zeidan, MD¹³ and Valeria Santini, MD¹⁴

¹University Hospital Leipzig, Leipzig, Germany
²Moffitt Cancer Center, Tampa, FL
³Hôpital St Louis/Paris 7 University, PARIS, FRA
⁴Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁵Vanderbilt University Medical Center, Nashville, TN
⁶Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁷UT Southwestern Medical Center, Dallas
⁸Columbia Presbyterian, New York, NY
⁹Myelodysplastic Syndrome Center, Columbia University Medical Center, New York, NY
¹⁰University Hospital of Düsseldorf, Düsseldorf, Germany
¹¹Geron Corporation, Parsippany, NJ
¹²Geron Corporation, Parsippany
¹³Yale University School of Medicine, New Haven, CT
¹⁴DMSC, MDS Unit, AOU Careggi, University of Florence, Firenze, Italy

Félix López Cadenas, MD^1*, Eva Lumbreras^2*, Teresa González, PhD^2*, Blanca Xicoy, MD^3*, Joaquín Sánchez-García, MD, PhD^4*, Rosa Coll, MD^5*, Bohrane Slama^6*, José Ángel Hernández-Rivas^7*, Sylvain Thepot^8*, Teresa Bernal, MD, PhD^9*, Agnès Guerci-Bresler, MD, PhD^10*, Guillermo Sanz, MD, PhD^11,12, Joan Bargay, MD, PhD^13*, Maria Luz Amigo, MD^14*, Raquel De Paz Arias, PhD^15*, Claude Preudhomme, PharmD, PhD^16,17, Aristoteles Giagounidis, MD¹⁸, Uwe Platzbecker, MD^19*, Stefan Wickenhauser, MD^20*, Katharina S. Goetze²¹, Ali Arar^22*, Jesús María Hernández-Rivas, MD, PhD^2,23, Sofía M Toribio Castelló^2*, Pierre Fenaux²⁴, Consuelo Del Cañizo, MD, PhD²⁵ and Maria Diez-Campelo, MD^26*

¹Hematology Department, Hospital Clínico Universitario de Salamanca, Salamanca, Spain
²Unidad de Diagnóstico Molecular y Celular del Cáncer, Centro de Investigación del Cáncer-Universidad de Salamanca (IBMCC, USAL-CSIC); Genética Molecular en Oncohematología, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain
³Hematology Department, Institut Català d’Oncologia-Hospital Germans Trias i Pujol, Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain
⁴Hematology Department, Hospital Reina Sofía, Córdoba, Spain
⁵Hematology Department. Institut Català d’Oncologia. Hospital Doctor Josep Trueta. Institut d'Investigació Biomèdica de Girona (IDIBGI), Universitat de Girona, Girona, Spain
⁶CH Avignon, Avignon, FRA
⁷Hematology Department, Hospital Universitario Infanta Leonor, Madrid, Spain
⁸Department of Clinical Hematology, Angers University Hospital, Angers, France
⁹Hospital Universitario Central de Asturias, Instituto Universitario (IUOPA), Instituto de investigación del Principado de Asturias (ISPA), Oviedo, Spain
¹⁰Service d'Hématologie, Centre Hospitalier Universtaire Brabois, Vandoeuvre-lès-Nancy, France
¹¹Istituto de Investigación Sanitaria La Fe, Valencia, Spain
¹²Hematology Deparment, Health Research Institute La Fe, Valencia, Spain
¹³Department of Hematology, Son Llatzer University Hospital/ IdISBa, Palma de Mallorca, Spain
¹⁴Hospital Universitario Morales Messeguer, Murcia, Spain
¹⁵Hematology, Hospital Universitario La Paz-Idipaz, Madrid, ESP
¹⁶Laboratory of Hematology, CHU Lille, Lille, France
¹⁷Cancer Research Institute, INSERM Unité Mixte de Recherche (UMR)-S 1172, F-59000 Lille, CHU Lille, Laboratory of Hematology, F-59000 Lille, Lille, France
¹⁸Department of Oncology, Hematology and Palliative Care, Marienhospital Düsseldorf, Düsseldorf, Germany
¹⁹Department for Hematology, Cell Therapy and Hemostaseology, University of Leipzig Medical Center, Leipzig, Germany
²⁰Service d’Hématologie, Centre Hospitalier Universitaire de Nîmes, Nîmes, France
²¹Department of Medicine III, Klinikum rechts der Isar, Technical University Munich (TUM), Munich, Germany
²²Centre Hospitalier Régional d’Orléans, Orleans, FRA
²³Department of Hematology, University Hospital of Salamanca, Salamanca, Spain
²⁴Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France
²⁵Departamento de Hematología, Hospital Clínico Universitario de Salamanca (CAUSA/IBSAL), Salamanca, Spain
²⁶Hematology Department, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain

Guillermo Garcia-Manero, MD¹, Kimo Bachiashvili, MD², Harshad Amin, MD^3,4*, Elie Traer, MD, PhD⁵, Daniel A. Pollyea, MD⁶, David A. Sallman, MD⁷, Aref Al-Kali, MD⁸, Larry D. Cripe, MD⁹, Jesus G Berdeja, MD¹⁰, Elizabeth A. Griffiths, MD¹¹, Sanjay R Mohan, MD, MSCI¹², Yuri Sano, MD¹³, Aram Oganesian, PhD^14*, Harold N. Keer, MD, PhD¹³ and Abdulraheem Yacoub, MD¹⁵

¹The University of Texas MD Anderson Cancer Center, Houston, TX
²University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, AL
³Boca Raton Clinical Research, Boca Raton, FL
⁴Boca Raton Cancer Research, Boca Raton, FL
⁵Oregon Health & Science University, Portland
⁶University of Colorado Cancer Center, Denver, CO
⁷Moffitt Cancer Center, Tampa, FL
⁸Mayo Clinic, Rochester, Rochester, MN
⁹Indiana University Health, Indianapolis, IN
¹⁰Sarah Cannon Research Institute, Nashville, TN
¹¹Roswell Park Comprehensive Cancer Center, Buffalo, NY
¹²Vanderbilt University School of Medicine, Vanderbilt Ingram Cancer Center, Nashville, TN
¹³Astex Pharmaceuticals Inc., Pleasanton, CA
¹⁴Astex Pharmaceuticals, Inc., Pleasanton, CA
¹⁵The University of Kansas Clinical Cancer Research Center, Leawood, KS

Amer M. Zeidan, MD¹, Caroline Fradette, PhD², Anna Rozova, MD^2*, Noemi Toiber Temin, MA^2* and Fernando Tricta, MD²

¹Yale University, New Haven, CT
²Chiesi Canada Corporation, Toronto, ON, Canada