-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

637.O1.6 637. Myelodysplastic Syndromes – Clinical and Epidemiological I

Symposia: Myelodysplastic Syndromes – Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Biological therapies, Acute Myeloid Malignancies, AML, MDS, clinical trials, adult, Clinical Practice (Health Services and Quality), Non-Biological therapies, Translational Research, Chemotherapy, Combination therapy, Clinical Research, drug development, Chronic Myeloid Malignancies, CMML, Diseases, Therapies, Immunotherapy, Biological Processes, Myeloid Malignancies, Pharmacology, molecular biology, Study Population, Human, pathogenesis
Monday, December 12, 2022: 2:45 PM-4:15 PM
243-245 (Ernest N. Morial Convention Center)
Moderators:
Jacqueline S. Garcia, MD, Dana-Farber Cancer Institute and Namrata Sonia Chandhok, MD, Yale New Haven Hospital
Disclosures:
No relevant conflicts of interest to declare.
TP53 alternations and management of higher risk MDS
2:45 PM

Amer M. Zeidan, MD1, Kiyoshi Ando, MD, PhD2, Odile Rauzy3*, Mehmet Turgut, MD4*, Ming-Chung Wang, MD5*, Roberto Cairoli6*, Hsin-An Hou, MD, PhD7*, Yok-Lam Kwong, MD8*, Montserrat Arnan Sangerman, PhD9*, Stef Meers10, Vinod A. Pullarkat, MD11*, Valeria Santini, MD, PhD12*, Kamel Malek13*, Flavia Kiertsman14*, Jiaying Lyu15*, Pedro Marques Ramos, PhD13*, Pierre Fenaux16, Yasushi Miyazaki, MD17 and Uwe Platzbecker, MD18

1Yale University and Yale Cancer Center, New Haven, CT
2Tokai University School of Medicine, Isehara, Japan
3Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France
4Ondokuz Mayıs University, Samsun, Turkey
5Chang Gung Memorial Hospital, Kaohsiung City, Taiwan
6Niguarda Cancer Center, Milan, Italy
7National Taiwan University Hospital, Taipei City, Taiwan
8Department of Medicine, The University of Hong Kong, Hong Kong, Hong Kong
9Institut Català d'Oncologia-Hospital Duran i Reynals, Barcelona, Spain
10AZ Klina, Brasschaat, Belgium
11City of Hope, Duarte, CA
12University of Florence, Florence, Italy
13Novartis Pharma AG, Basel, Switzerland
14Novartis Pharmaceuticals Corporation, East Hanover, NJ
15Novartis, China, Shanghai, China
16Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France
17Nagasaki University, Nagasaki, Japan
18University Hospital Leipzig, Leipzig, Germany

3:00 PM

Michael R. Savona, MD1, James K McCloskey, MD2, Elizabeth A. Griffiths, MD3, Karen Yee, MD4, Amer M. Zeidan, MD5, Aref Al-Kali, MD6, Joachim Deeg, MD7*, Prapti Patel, MD8, Mitchell Sabloff, MSc, MD, FRCPC9, Mary-Margaret Keating, MD, FRCPC10, Kim-Hien Dao, DO11,12, Nancy Zhu, MD13*, Nashat Y. Gabrail, MD14*, Salman Fazal, MD15, Joseph J. Maly, MD16, Olatoyosi Odenike, MD17, Hagop Kantarjian, MD18, Amy E. DeZern, MD19, Casey L. O'Connell, MD20, Gail J. Roboz, MD21, Lambert Busque, MD22, Rena Buckstein23, Harshad Amin, MD24*, Jasleen K. Randhawa, MD25, Brian Leber, MD26,27, Aram Oganesian, PhD11*, Winny Chan, PharmD11*, Yong Hao, MD, PhD11*, Mohammad Azab, MD11 and Guillermo Garcia-Manero, MD28

1Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN
2John Thuerer Cancer Center, Hackensack Medical Center, Hackensack, NJ
3Roswell Park Comprehensive Cancer Center, Buffalo, NY
4Princess Margaret Cancer Centre, Toronto, ON, Canada
5Hematology, Yale University and Yale Cancer Center, New Haven, CT
6Mayo Clinic, Rochester, Rochester, MN
7Fred Hutchinson Cancer Center, Seattle, WA
8University of Texas Southwestern Medical Center, Dallas, TX
9Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
10Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
11Astex Pharmaceuticals, Inc., Pleasanton, CA
12Oregon Health & Science University, Portland, OR
13University of Alberta, Edmonton, AB, Canada
14Gabrail Cancer Center, Canton, OH
15West Penn Hospital, Allegheny Health Network, Pittsburgh, PA
16Norton Cancer Institute, Louisville, KY
17University of Chicago, Chicago, IL
18The University of Texas MD Anderson Cancer Center, Houston, TX
19The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
20USC Keck School of Medicine, University of Southern California, Los Angeles, CA
21Weill Cornell Medicine, The New York Presbyterian Hospital, New York, NY
22Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada
23Division of Hematological Pathology, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
24Boca Raton Clinical Research, Boca Raton, FL
25Houston Methodist Research Institute, Houston, TX
26McMaster University, Hamilton, ON, Canada
27Juravinski Cancer Centre, Hamilton, ON, Canada
28Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

3:15 PM

David A. Sallman, MD1, Amy E. DeZern, MD2, Arlene A. Gayle, MD3, Stuart J. Kahn, MD4*, Eric Padron, MD5, Jeffrey E. Lancet, MD6, Andrew Kuykendall, MD7, Kendra Sweet, MD8, Onyee Chan, MD7, Dean Y. Maeda, PhD4*, Aaron D. Schuler, PhD4*, John A. Zebala, MD, PhD4* and Rami S. Komrokji9

1Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
2Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
3AdventHealth Orlando, Orlando, FL
4Syntrix Pharmaceuticals, Auburn, WA
5Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
6Department of Malignant Hematology, H. Lee Moffitt Cancer Ctr. %26 Rsrch. Institute, Tampa, FL
7Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
8Department of Hematology and Oncology, Moffitt Cancer Center, Tampa, FL
9H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL

3:30 PM

Anna Stengel, PhD, Manja Meggendorfer, PhD, Wencke Walter, PhD*, Constance Baer, PhD, Niroshan Nadarajah*, Stephan Hutter, PhD*, Wolfgang Kern, MD, Torsten Haferlach, MD and Claudia Haferlach, MD

MLL Munich Leukemia Laboratory, Munich, Germany

3:45 PM

Waled Bahaj, MD1,2, Tariq Kewan, MD3,4*, Carmelo Gurnari, MD1,5, Arda Durmaz1*, BEN Ponvilawan, MD1*, Ishani Pandit1*, Yasuo Kubota, MD, PhD1*, Olisaemeka Ogbue6, Mai Aly, MD, BSc, MS1,7*, Yazan F. Madanat, MD8, Taha Bat, MD9, Suresh Kumar Balasubramanian, MD10, Minako Mori, MD, PhD1*, Manja Meggendorfer, PhD11, Hetty E. Carraway, MD, MBA12, Sudipto Mukherjee, MD, PhD, MPH12, Mikkael A. Sekeres, MD13, Torsten Haferlach, MD11, Valeria Visconte, PhD1 and Jaroslaw P. Maciejewski, MD, PhD, FACP1

1Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
2Brown Cancer Center, University of Louisville, Louisville, KY
3Smilow Cancer Center, Yale New Haven Hospital, New Haven, CT
4Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland Clinic, OH
5Department of Biomedicine and Prevention, Ph.D. in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy
6Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Rocky River, OH
7Assiut University, Clinical Hematology unit, Faculty of Medicine, Assiut, Egypt
8Division of Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
9Division of Hematology and Oncology, UT Southwestern Medical Center, Dallas, TX
10Department of Oncology, Wayne State University/ Karmanos Cancer Institute, Detroit, MI
11MLL Munich Leukemia Laboratory, Munich, Germany
12Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
13University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL

4:00 PM

Guillermo Garcia-Manero, MD1, Vera Adema, PhD2*, Samuel Urrutia, MD2*, Feiyang Ma, PhD3*, Hui Yang, MD, PhD2, Irene Ganan-Gomez, PhD2, Gautam Borthakur, MD2, Koichi Takahashi, MD, PhD4, Nicholas Short, MD2, Ghayas C. Issa, MD2, Kelly S. Chien, MD2, Guillermo Montalban-Bravo, MD2, Joby Joseph2* and Simona Colla, PhD2*

1Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Division of Rheumatology, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI
4Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX

*signifies non-member of ASH