-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
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634.O3.6 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Towards Personalized Medicine in Myeloproliferative Neoplasms and Mastocytosis: New and Repurposed Drugs for Unmet Clinical Needs

Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Biological therapies, adult, Translational Research, Non-Biological therapies, MPN, Clinical Research, Combination therapy, hematopoiesis, drug development, Chronic Myeloid Malignancies, Diseases, Therapies, Adverse Events, Biological Processes, Myeloid Malignancies, Study Population, Human
Sunday, December 11, 2022: 4:30 PM-6:00 PM
217-219 (Ernest N. Morial Convention Center)
Moderators:
Natasha Szuber, MD, MSc, Maisonneuve-Rosemont Hospital and Deepti H. Radia, MRCPI, FRCPath, Guy's and St Thomas' NHS Foundation Trust
Disclosures:
Radia: Cogent Biosciences: Consultancy, Honoraria, Other: Steering committee member for APEX study; Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Educational events; Blueprint Medicines Corporation: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Educational events, Research Funding.
In this session data for new agents for rarer myeloproliferative entities such as FGFR1 rearranged  disease, mastocytosis and new data with JAK inhibitors and interferon for myelofibrosis
4:30 PM

Deepti H. Radia, MRCPI, FRCPath1*, Jason Gotlib, MD, MS2, Mark W. Drummond, PhD, FRCPath3*, Tracy I. George, MD4, Hui-Min Lin, PhD5*, Saša Dimitrijević, PhD6*, Javier I. Munoz-Gonzalez, PhD6*, Ilda Bidollari, MD, MBA5*, Michael W. Deininger, MD, PhD7, Daniel J. DeAngelo, MD, PhD8 and Andreas Reiter, MD9

1Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom
2Department of Hematology, Stanford Cancer Institute/Stanford University School of Medicine, San Carlos, CA
3Beatson Cancer Centre, Glasgow, United Kingdom
4ARUP Laboratories, Salt Lake City, UT
5Blueprint Medicines Corporation, Cambridge, MA
6Blueprint Medicines (Switzerland) GmbH, Zug, Switzerland
7Versiti Blood Research Institute, Milwaukee, WI
8Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
9Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany

4:45 PM

Daniel J. DeAngelo, MD, PhD1*, Vinod A. Pullarkat, MD2*, Miguel Piris-Villaespesa3*, Tracy I. George, MD4, Jay L. Patel, MD5*, Celalettin Ustun, MD6, Prithviraj Bose, MD7, Mark L Heaney, MD, PhD8*, Jessica Sachs, MD9, Lei Sun, PhD9*, Amanda Pilla9*, Benjamin Exter, PharmD9*, Hina A. Jolin, PharmD9* and Tsewang Tashi, MD10*

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Department of Hematology and Hematopoietic Cell Transplantation and Gehr Family Center for Leukemia Research, City of Hope Comprehensive Cancer Center, Duarte, CA
3Hospital Universitario Ramón y Cajal, Madrid, Spain
4ARUP Laboratories, Salt Lake City, UT
5ARUP Laboratories, University of Utah, Salt Lake City, UT
6Division of Hematology, Oncology, and Cell Therapy, Rush University Medical Center, Chicago, IL
7The University of Texas MD Anderson Cancer Center, Houston, TX
8Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY
9Cogent Biosciences, Inc., Cambridge, MA
10Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT

5:00 PM

Aaron T. Gerds, MD, MS1, Ruben Mesa, MD, FACP2, Alessandro M Vannucchi, MD3, Haifa Kathrin Al-Ali, MD4*, David Lavie, MD5*, Andrew Kuykendall, MD6, Sebastian Grosicki, MD, PhD7, Alessandra Iurlo, MD, PhD8*, Yeow Tee Goh, MBBS9, Mihaela Lazaroiu, MD10, Miklos Egyed, MD, PhD11*, Maria Laura Fox, MD12*, Donal P. McLornan, MD, PhD13*, Andrew Charles Perkins, MBBS, PhD14, Sung-Soo Yoon, MD, PhD15,16, Vikas Gupta, MD, FRCP, FRCPath17, Jean-Jacques Kiladjian, MD18, Rafe Donahue, PhD19*, Jun Kawashima, MD19* and Srdan Verstovsek, MD, PhD20

1Department of Hematology and Medical Oncology,, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
2UT Health San Antonio Cancer Center, San Antonio, TX
3University of Florence, Firenze, Italy
4University Hospital of Halle, Halle, Germany
5Hadassah-Hebrew University Medical Centre, Jerusalem, Israel
6Department of Malignant Hematology, H. Lee Mofitt Cancer Center, Tampa, FL
7Medical University of Silesia, Katowice, Poland
8Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
9Department of Hematology, Singapore General Hospital, Singapore, Singapore
10Policlinica de Diagnostic Rapid, Brasov, Romania
11Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary
12University Hospital Vall d’Hebron, Barcelona, Spain
13Haematology Department, Guy's and St Thomas' NHS Trust, London, United Kingdom
14Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
15Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South)
16Seoul National University Hospital, Seoul, Korea, Republic of (South)
17Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada
18Université de Paris, AP-HP, Hôpital Saint-Louis, Centre d’Investigations Cliniques, Paris, France
19Sierra Oncology Inc., San Mateo, CA
20Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX

5:15 PM

Stephen T Oh, MD, PhD1, Ruben Mesa, MD, FACP2, Claire N. Harrison, DM3, Prithviraj Bose, MD4, Aaron T. Gerds, MD, MS5, Mark L. Heaney, MD6, Vikas Gupta, MD, FRCP, FRCPath7, Bart L. Scott, MD8, Jean-Jacques Kiladjian, MD9, Alessandro Lucchesi, MD, PhD10*, Sarah Buckley, MD11*, Shanthakumar Tyavanagimatt, PhD11*, Karisse Roman-Torres11*, John Mascarenhas, MD12 and Srdan Verstovsek, MD, PhD13

1Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO
2UT Health San Antonio MD Anderson Cancer Center, San Antonio, TX
3Guys and St Thomas NHS Trust, London, United Kingdom
4The University of Texas MD Anderson Cancer Center, Houston, TX
5Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
6Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY
7Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
8Fred Hutchinson Cancer Research Center, Seattle, WA
9Hopital Saint-Louis, Paris, France
10Hematology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, FC, Italy
11CTI BioPharma, Seattle, WA
12Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
13MD Anderson Cancer Center, University of Texas, Houston, TX

5:30 PM

Harinder Gill, MD, MBBS, FRCP, FRCPath1, Lester Au1*, Rita Yim, PhD1*, Lynn Chin1*, Vivian Li1*, Paul Lee1*, Garret MK Leung, MBBS1*, Carmen Lee1*, Tony Kwun Yat Wu, MBBS, BSc1*, Cheong Ngai1*, Ryan Ho1*, Albert Chun Fung Sin2*, Hsin-An Hou, MD, PhD3, Chih-Cheng Chen, MD4 and Yok-Lam Kwong, MD1*

1Department of Medicine, The University of Hong Kong, Hong Kong, Hong Kong
2Department of Pathology, The University of Hong Kong, Hong Kong, Hong Kong
3Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
4Division of Hematology and Oncology, Department of Medicine, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan, Taiwan

5:45 PM

Joseph Scandura, MD, PhD1, Srdan Verstovsek, MD, PhD2, Marina Kremyanskaya, MD, PhD3, Moshe Talpaz, MD4, Raajit K Rampal, MD, PhD5, Alessandro Vannucchi, MD6, Vikas Gupta, MD, FRCP, FRCPath7, Francesca Palandri, PhD, MD8*, Andrea Patriarca, MD9*, Prithviraj Bose, MD10, Dong Chen, M.D., Ph.D11, Oksana Zavidij, PhD12*, Jike Cui, PhD12*, Tzuu-Wang Chang, PhD12*, Pietro Taverna, PhD12, John Mascarenhas, MD13 and Claire N. Harrison, DM14

1Richard T. Silver, M.D. Myeloproliferative Neoplasms (MPN) Center, Weill Cornell Medicine, New York, NY
2MD Anderson Cancer Center, Houston, TX
3Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
4University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
5Memorial Sloan Kettering Cancer Center, New York, NY
6University of Florence, Azienda Ospedaliero Universitaria Careggi, CRIMM, Florence, Italy
7Department of Medicine, University of Toronto, Toronto, ON, Canada
8IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", Bologna, Italy
9Hematology Unit, Department of Translational Medicine, University of Eastern Piedmont and AOU Maggiore della Carità, Novara, Italy
10The University of Texas MD Anderson Cancer Center, Houston, TX
11Mayo Clinic, Rochester, MN
12Constellation Pharmaceuticals, Inc., a MorphoSys Company, Boston, MA
13Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
14Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

*signifies non-member of ASH