Naranie Shanmuganathan, MBBS, FRACP, FRCPA^1,2, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^3,4, Carol Wadham, PhD^5*, Nur Hezrin Shahrin, PhD^5*, Adelina Fernandes^6*, Jinghua Feng, PhD^7*, Verity A Saunders^8*, Ming Lin^7*, Rosalie Kenyon^7*, Rob King^7*, Paul Wang, PhD^5*, David M Ross, MBBS, PhD, FRACP, FRCPA^9,10*, Andreas W Schreiber, PhD^7*, Timothy Hughes, MD, MBBS, FRACP, FRCPA¹¹ and Susan Branford, PhD⁵

¹Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, Australia
²Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia
³Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia
⁴Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia
⁵Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, Australia
⁶University of Adelaide, Adelaide, Australia
⁷ACRF Cancer Genomics Facility, Adelaide, Australia
⁸Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, Australia
⁹Royal Adelaide Hospital and SA Pathology, Adelaide, Australia
¹⁰Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
¹¹South Australian Health and Medical Research Institute SAHMRI, Adelaide, SA, Australia

Thomas Ernst, MD¹, Lioba Schönfeld^1*, Jenny Rinke, PhD^1*, Anna Hinze^1*, Saskia N. Nagel^1*, Vivien Schäfer, PhD^1*, Thomas Schenk, MD^1*, Christian Fabisch, PhD^1*, Tim H. Brümmendorf, MD², Andreas Burchert, MD³, Philipp le Coutre, MD⁴, Stefan W. Krause, MD^5*, Susanne Saussele, MD ⁶, Fatemeh Safizadeh^7*, Markus Pfirrmann, PhD^7* and Andreas Hochhaus, MD⁸

¹Hematology/Oncology, Jena University Hospital, Jena, Germany
²Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, RWTH Aachen University, Aachen, Germany
³Department of Hematology and Oncology, University Hospital Giessen and Marburg, Marburg, Germany
⁴Department of Hematology and Oncology, Charité - University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany
⁵Department of Hematology and Medical Oncology, University Hospital Erlangen, Erlangen, Germany
⁶Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
⁷Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie - IBE, Ludwig-Maximilians-Universität, Munich, Germany
⁸Department of Internal Medicine II, Hematology and Oncology, University Hospital Jena, Jena, Germany

Elias Jabbour, MD¹, Koji Sasaki, MD¹, Ghayas C. Issa, MD², Fadi Haddad, MD^1*, Guillermo Garcia-Manero, MD³, Tapan M. Kadia, MD⁴, William G. Wierda, MD, PhD⁵, Musa Yilmaz, MD⁴, Courtney D. DiNardo, MD, MSCE¹, Jeffrey Skinner, MHA^6*, Naveen Pemmaraju, MD¹, Sara E Dellasala, BS^1*, Sherry A. Pierce, BSN, BA^1*, Jorge E. Cortes, MD⁷ and Hagop Kantarjian, MD⁸

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
³Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁵The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX
⁷Georgia Cancer Center, Augusta, GA
⁸Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Taehyung Kim, MSc^1,2,3, Daniela Žácková, MD, PhD^4*, Ivana Ježíšková, PhD^4*, Anežka Kvetková, MD^4*, Tomáš Jurček, PhD^4*, Young Seok Yoo, BSc^1*, Hyewon Lee, MD^1,5, Kyoung Ha Kim, MD, PhD^1,6,7, Myung Hee Chang, MD^1,8*, Seong Yoon Yi, MD^1,9*, Jessie J. F. Medeiros^10,11,12, Sagi Abelson, PhD^10,11* and Dennis Kim, MD, PhD^1,13

¹Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
²Department of Computer Science, University of Toronto, Toronto, ON, Canada
³The Donnelly Centre for Cellular and Biomolecular Research, Donnelly Centre For Cellular & Biomolecular Research, Toronto, ON, Canada
⁴Department of Internal Medicine Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic
⁵Department of Internal Medicine, Center for Hematologic Malignancies, National Cancer Center, Goyang, Korea, Republic of (South)
⁶Division of Hematology and Oncology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, SEOUL, South Korea
⁷Department of Internal Medicine, Soonchunhyang University College of Medicine, Soonchunhyang University Hospital, Seoul, Korea, Republic of (South)
⁸National Health Insurance Service Ilsan Hospital, Ilsan, Korea, Republic of (South)
⁹Department of Internal Medicine, Inje University Ilsan-Paik Hospital, Goyang, Korea, Republic of (South)
¹⁰Ontario Institute for Cancer Research, Toronto, ON, Canada
¹¹Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
¹²Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
¹³Hans Messner Allogeneic Blood and Marrow Transplant Unit, Princess Margaret Cancer Centre, Toronto, ON, Canada

Sen Yang, MD^1*, Xiaoshuai Zhang^2*, Robert Peter Gale³, Yanli Zhang^4,5*, Xin Du^6*, Jianyu Weng, MD^7,8,9,10, Huanling Zhu^11*, Ling Pan, MD, PhD^12,13,14*, Yun-fan Yang, MD^15*, Li Meng^16*, Zhenfang Liu^17*, Xiaoli Liu^18,19*, Na Xu^18*, Chunyan Chen, PhD^20*, Xiaodong WANG, MD^21*, Rong Liang^22*, Jian Huang^23*, Guohui Li^24*, Chunshui Liu^25*, Hai Lin^26*, Jianda Hu^{27,28,29,30,31,32,33}, Li Fei^{34,35,36,37,38,39}, Bingcheng Liu^40*, Weiming Li^41*, Zhuogang Liu, MD^42*, Wei Yang^43*, Xiao Jun Huang, MD^{2,44,45,46,47,48,49,50,51,52,53,54,55} and Qian Jiang^47*

¹Peking University Institute of Hematology, Peking University People’s Hospital, Beijing, AL, China
²Peking University People's Hospital, Beijing, China
³Centre for Haematology Research, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom
⁴Henan Cancer Hospital, Zhengzhou, China
⁵Department of Hematology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China
⁶Department of Hematology, Shenzhen Second People's Hospital, Guangdong, China, Shenzhen, China
⁷Guangdong general hospital/Guangdong Academay of Medical Sciences, GUANGZHOU, China
⁸Guangdong General Hospital, Guangzhou, China
⁹Department of Hematology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
¹⁰Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
¹¹Department of Hematology, West China Hospital of Sichuan University, Chengdu Sichuan, China, Sichuan, China
¹²Department of Hematology, West China Hospital,Sichuan University, Chengdu, China
¹³Department of Hematology and Hematology Research Laboratory , West China Hospital, Sichuan University, Chengdu, China
¹⁴West China Hospital of Sichuan University, Chengdu, China
¹⁵Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
¹⁶Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
¹⁷Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
¹⁸Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
¹⁹Department of Hematology, Nanfang Hospital,Southern Medical University, Guangzhou, China
²⁰Department of Hematology, Qilu Hospital, Shandong University School of Medicine, Jinan, P,R, China, Jinan, Shandong, CHN
²¹Sichuan Provincial People’s Hospital, Affliated Hospital of University of Electronic Science and Technology of China, Chengdu, CHN
²²Department of Hematology, Xijing Hospital, Air Force Medical University, Xi'an, China, Xi'an, China
²³The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu, China
²⁴Department of Hematology, Tangdu Hospital, Fourth Military Medical University, Baqiao District, Xinshi Road No1, Xi'an, 710038, China., Xi'an, China
²⁵Department of Hematology, The First Hospital of Jilin University, Changchun., Changchun, China
²⁶Department of Hematology and Oncology, Jilin University First Hospital, Jilin, China., Jilin, China
²⁷Department of Hematology, Fujian Medical University Union Hospital，Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fuzhou, China
²⁸Department of Hematology, Union Hospital, Fujian Medical University, Fuzhou, China
²⁹Fujian Medical University Union Hospital, Fuzhou, Fujian, China
³⁰Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
³¹Department of Hematology, Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
³²Department of Hematology, Union Hospital, Fujian Institute of Hematology, Fuzhou, China
³³Department of Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
³⁴Institute of Lymphoma and Myeloma, Nanchang University, Nanchang, China, Nanchang, China
³⁵The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China
³⁶Department of Hematology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China 2 Depart, Nanchang, CHN
³⁷the First Affiliated Hospital of Nanchang University, Nanchang, China
³⁸Jiangxi Key Laboratory of Molecular Diagnosis and Precision Medicine, the First Affiliated Hospital of Nanchang University, Nanchang, China
³⁹Jiangxi Clinical Research Center for Hematologic Disease, Nanchang, China
⁴⁰State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China
⁴¹Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⁴²Shengjing Hospital of China Medical University, Shenyang, China
⁴³Department of Hematology, Shengjing Hospital of China Medical University, Liaoning, China, Liaoning, China
⁴⁴National Clinical Research Center for Hematologic Disease, Beijing, China
⁴⁵Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematology Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁴⁶Peking-Tsinghua Centre for Life Science, Beijing, China
⁴⁷Peking University People’s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, National Clinical Research Center for Hematologic Disease, Beijing, China
⁴⁸Beijing Engineering Lab for Cellular Therapy, Beijing, China
⁴⁹Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Peking University People's Hospital, Beijing, China
⁵⁰Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China
⁵¹Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁵²Peking University People's Hospital,Peking University Institute of Hematology, Beijing, China
⁵³Collaborative Innovation Center of Hematology, Peking University, Beijing, China
⁵⁴Peking University People’s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁵⁵Peking University People’s Hospital, Peking University Institute of Hematology,National Clinical Research Center for Hematologic Disease, Beijing, China

Annamaria Brioli, MD, PhD^1*, Elza Lomaia, MD, PhD^2*, Christian Fabisch, PhD^3*, Tomasz Sacha, MD, PhD^4*, Hana Klamová, MD, PhD^5*, Elena Morozova, MD, PhD^6*, Aleksandra Golos, MD, PhD^7*, Philipp Ernst, MD^3*, Ulla Olsson-Strömberg, MD, PhD^8*, Jiri Mayer, Prof, MD^9*, Franck E. Nicolini, MD, PhD¹⁰, Han Bao^11*, Fausto Castagnetti, MD, PhD¹², Elzbieta Patkowska, MD, PhD^13*, Klaus Hirschbühl, MD^14*, Edyta Paczkowska, MD, PhD^15*, Anne Parry, MD^16*, Astghik Voskanyan, MD^17*, Susanne Saussele, MD ¹⁸, Georg-Nikolaus Franke, MD^19*, Alexander Kiani, MD^20*, Edgar Faber, MD, PhD, prof^21*, Krzysztof Lewandowski, MD PhD^22*, Stefan W. Krause, MD^23*, Elke Dammann^24*, Peter Anhut, MD^25*, Justyna Gil, MD^26*, Thomas Südhoff, MD^27*, Sonja Heibl, MD^28*, Markus Pfirrmann, PhD^29*, Andreas Hochhaus, MD³ and Michael Lauseker, PhD^11*

¹Klinik für Innere Medizin C, Universitätsmedizin Greifswald, Greisfwald, Germany
²Almazov National Medical Research Centre, St. Petersburg, Russian Federation
³Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany
⁴Department of Hematology, Jagiellonian University Medical College, Krakow, Poland
⁵Institute of Clinical and Experimental Hematology of the First Faculty of Medicine, Charles University and Institute of Hematology and Blood Transfusion, Prague, Czech Republic
⁶RM Gorbacheva Research Institute, Pavlov University, St. Petersburg, Russian Federation
⁷Hemato-oncology Department, Copernicus Memorial Hospital, Lodz, Poland
⁸Department of Hematology, University Hospital Uppsala, Uppsala, Sweden
⁹Hematology and Oncology, University Hospital Brno, Czech Republic, Brno, Czech Republic
¹⁰Centre Hospitalier Lyon Sud, LYON Cedex 03, France
¹¹Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Ludwig-Maximillians-University, Munich, Germany
¹²Istituto di Ematologia “Seràgnoli”, Department of Experimental, Diagnostic and Specialty Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy
¹³Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
¹⁴Section for Stem Cell Transplantation, University Hospital Augsburg, Augsburg, Germany
¹⁵Department of General Pathology, Pomeranian Medical University, Szczecin, Poland
¹⁶Centre Hospitalier Annecy Genevois, Annecy, France
¹⁷Hematology Center after Prof. R.Yeolyan, Yerevan, Armenia
¹⁸III. Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Mannheim, Germany
¹⁹Department for Hematology, Cell Therapy and Hemostaseology, University of Leipzig Medical Center, Leipzig, Germany
²⁰Department of Medicine IV, Klinikum Bayreuth GmbH, Bayreuth, Germany
²¹Department of Hemato-oncology, Faculty Hospital and Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic
²²Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
²³Medizinische Klinik 5, Universitätsklinikum Erlangen, Erlangen, Germany
²⁴Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
²⁵Onkologische Schwerpunktpraxis Anhut, Kronach, Germany
²⁶Department of Hematooncology, Oncology Centre of the Podkarpackie Province, Brzozow, Poland
²⁷Department Hematology and Oncology, Klinikum Passau, Passau, Germany
²⁸4th Medical Dept. of Internal Medicine, Hematology, Internistic Oncology and Palliative Medicine, Klinikum Wels-Grieskirchen GmbH, Wels, Austria
²⁹Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Ludwig-Maximilians-University, München, Germany