-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

627.O1.6 627. Aggressive Lymphomas: Clinical and Epidemiological: Treatment of CNS Lymphoma, Neurologic Toxicities, and Relapsed/Refractory DLBCL

Symposia: Aggressive Lymphomas: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Biological therapies, adult, non-Hodgkin lymphoma, Lymphomas, epidemiology, elderly, Clinical Research, Chimeric Antigen Receptor (CAR)-T Cell Therapies, B Cell lymphoma, Combination therapy, health outcomes research, Diseases, real-world evidence, Therapies, aggressive lymphoma, Adverse Events, Lymphoid Malignancies, registries, Study Population, Human, Transplantation
Saturday, December 10, 2022: 12:00 PM-1:30 PM
New Orleans Theater C (Ernest N. Morial Convention Center)
Anthony N. Audino, MD, Nationwide Children's Hospital and Gareth P. Gregory, MBBS, PhD, FRACP, FRCPA, ARRAY(0xe0adba4)
No relevant conflicts of interest to declare.
This session will focus on retrospective clinical evidence to guide best treatment of primary central nervous system lymphoma, neurologic toxicities of CAR T-cell therapy, and choosing the best therapy for relapsed/refractory diffuse large B cell lymphoma
12:00 PM

Vivek Patel, MD1, Shakthi Bhaskar, MD1, Stephen J. Schuster, MD2, Loretta J. Nastoupil, MD3, Miguel-Angel Perales, MD4, Roni Shouval, MD, PhD4, Joseph P. McGuirk, DO5, Richard T. Maziarz, MD6, Andy Chen, MD, PhD7, Veronika Bachanova, MD, PhD8, David L. Porter, MD9, Michael R. Bishop, MD10, Peter A. Riedell, MD10 and Olalekan O. Oluwole, MBBS1

1Vanderbilt University Medical Center, Nashville, TN
2Division of Hematology-Oncology/Department of Medicine, University of Pennsylvania, Philadelphia, PA
3Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
4Adult Bone Marrow Transplant Service, Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
5Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Kansas City, KS
6Knight Cancer Institute, Oregon Health and Science University, Portland, OR
7Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health and Science University, Portland, OR
8Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
9Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
10The David and Etta Jonas Center for Cellular Therapy, University of Chicago, Chicago, IL

12:15 PM

Fleur A De Groot1*, Jeanette K. Doorduijn, MD, PhD2, Mirian Brink, PhD3*, Ruben A.L. De Groen1*, Lorraine M. De Haan4*, Troy Noordenbos4*, Aniko Sijs-Szabo1*, King Hong Lam, MD, PhD5*, Arjan Diepstra, M.D., Ph.D.6, Liane te Boome7, Valeska Terpstra8*, Lara H. Böhmer, MD9*, Josée M. Zijlstra, MD PhD10, Lianne Koens11*, Marc Durian, MD12*, Mirjam A. Oudshoorn1*, Hendrik Veelken, MD, PhD 1, Marjolein W.M. Van Der Poel13, Myrurgia Abdul Hamid14*, Wendy B.C. Stevens, MD15*, J L.M van Rooij16*, Rimke Oostvogels, MD PhD17*, Karen J. Neelis, MD18*, Michiel van den Brand, MD19*, F.J. Sherida H. Woei-a-Jin, MD MSc20*, Thomas Tousseyn21*, Daan Dierickx, MD22*, Patty M. Jansen4*, Marie Jose Kersten, MD, PhD23,24, Jacoline Bromberg, MD25*, Marcel Nijland, MD, PhD26* and Joost S.P. Vermaat, MD, PhD1

1Department of Hematology, Leiden University Medical Center, Leiden, Netherlands
2Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
3Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands, Utrecht, Netherlands
4Department of Pathology, Leiden University Medical Center, Leiden, Netherlands
5Erasmus MC, Rotterdam, NLD
6Department of Pathology and Medical Biology, University of Groningen, Groningen, Netherlands
7Department of Hematology, Haaglanden Medisch Centrum, Den Haag, Netherlands
8Pathology, Haaglanden MC, Den Haag, Netherlands
9Department of Hematology, Haga Teaching Hospital, The Hague, Netherlands
10Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands, Amsterdam, Netherlands
11Department of Pathology, Amsterdam UMC, AMC, Amsterdam, Netherlands
12Department of Hematology, St Elisabeth Hospital, Tilburg, Netherlands
13Maastricht University Medical Center, Maastricht, Netherlands
14Maastricht University, Urmond, NLD
15dept hematology, Radboud UMC, Nijmegen, Netherlands
16Neurology, University Medical Center Utrecht, Utrecht, Netherlands
17Department of Hematology, University Medical Center Utrecht, Utrecht, Netherlands
18Department of Radiotherapy, Leiden University Medical Center, Leiden, Netherlands
19Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands
20Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium
21Department of Pathology, UZ Leuven, Leuven, Belgium
22University Hospitals Leuven, Leuven, Belgium
23Department of Hematology, Academic Medical Center, Amsterdam, Noord Holland, Netherlands
24Lymphoma and Myeloma Center Amsterdam-LYMMCARE, Amsterdam, Netherlands
25dept of Neuro-Oncology, Daniel den Hoed Cancer Ctr., Rotterdam, Netherlands
26University Medical Center Groningen, Groningen, Netherlands

12:30 PM

Edward Poynton1,2*, Emily Chernucha3*, James Day2*, Catherine Prodger4*, David Hopkins5*, Pallav Rakesh6*, Tess O’Neill7*, Nisha Thakrar2*, Ayse Akarca8*, Sabine Pomplun8*, Teresa Marafioti, MD8*, Maria Calaminici, MD, PhD1*, Sridhar Chaganti, MD9*, Pam McKay, MBChB, FRCP, FRCPath5*, Jeffery Smith, MBChB, MRCP, FRCPath10*, Toby A. Eyre, MBChB, DipMedEd, MRCP, FRCPath, MD11*, Nicolas Martinez-Calle3*, Kate Cwynarski, MD12*, Christopher P. Fox13* and Jessica Okosun, PhD1,7

1Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
2Department of Clinical Haematology, University College London Hospital, London, United Kingdom
3Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom
4Churchill Cancer Center, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
5Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom
6Centre for Clinical Haematology, University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom
7Department of Haemato-Oncology, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom
8Department of Histopathology, University College London Hospital, London, United Kingdom
9Department of Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom
10Clatterbridge Cancer Centre, Liverpool University Hospital, Liverpool, United Kingdom
11Oxford University Hospitals NHS Foundation Trust, Churchill Cancer Center, Oxford, United Kingdom
12University College London Hospitals NHS Foundation Trust, London, United Kingdom
13Department of Hematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom

12:45 PM

Joanna Zurko, MD1, Geoffrey Shouse, PhD, DO2, Pallawi Torka, MD3, Tamara K. Moyo, MD, PhD4*, Jason T. Romancik, MD5, Imran A. Nizamuddin, MD6, Kaitlin Annunzio, DO7, Jieqi Liu, MD8*, Stefan K. Barta, MD9, Robert Ferdman, MD3*, Rahul Bhansali, MD10*, Jonathon B. Cohen, MD, MS11, Sayan Mullick Chowdhury, DO, PhD12*, Nirav N. Shah, MD13, Elyse I. Harris, MD14, Vaishalee P. Kenkre, MD1, McKenzie Sorrell, DO15, Brian T. Hess, MD15, Deborah M. Stephens, DO16, Lindsey A. Fitzgerald, MD17, Thomas A. Ollila, MD18, Ishan Roy19*, Shuo Ma, MD20, Jane N. Winter, MD21, Barbara Pro, MD22, Jonathan Moreira, MD23, Leo I. Gordon, MD23, Alexey V Danilov, MD24, Andrew M. Evens, DO, MBA, MMSc25, Narendranath Epperla, MD, MS26 and Reem Karmali, MD, MSc27

1Carbone Cancer Center, University of Wisconsin, Madison, WI
2Department of Hematology/HCT, City of Hope National Medical Center, Duarte, CA
3Roswell Park Comprehensive Cancer Center, Buffalo, NY
4Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
5Department of Hematology and Medical Oncology, Winship Cancer Institute at Emory University, Atlanta, GA
6Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL
7The Ohio State University, Columbus, OH
8Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ
9Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
10Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
11Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University, Atlanta, GA
12Ohio State University Medical Center, Columbus, OH
13Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
14Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI
15Hollings Cancer Center, Medical University of South Carolina, Charleston, SC
16Huntsman Cancer Institute, Salt Lake City, UT
17Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT
18Lifespan Cancer Institute, Brown University, Providence, RI
19Northwestern University, Chicago, IL
20Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL
21Feinberg School of Medicine, Northwestern University, Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Chicago, IL
22Division of Hematology and Oncology, Northwestern University, Chicago, IL
23Department of Medicine, Division of Hematology/Oncology and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Northwestern University Feinberg School of Medicine, Chicago, IL
24City of Hope Comprehensive Cancer Center, Duarte, CA
25Rutgers Cancer Institute of New Jersey, Warren, NJ
26The Ohio State University Comprehensive Cancer Center, Columbus, OH
27Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL

1:00 PM

Gloria Iacoboni, MD1*, Josu Iraola-Truchuelo2*, Alberto Mussetti3*, Paula Fernández-Caldas4*, Víctor Navarro Garcés5*, ANA Africa Martin Lopez6*, Javier Delgado7*, Ariadna Pérez Martínez8*, Manuel Guerreiro, MD9*, Ana Carolina Carolina Caballero Gonzalez, MD10*, Nuria Martínez-Cibrián11*, Hugo Daniel Luzardo Henriquez12*, Jose M. Sanchez, MD13*, Juan-Manuel Sancho, MD, PhD14*, Pere Barba, MD1*, Mi Kwon, MD, PhD15*, Lucía López Corral, MD6*, Rafael Hernani, MD8*, Juan Luis Reguera, MD7*, Anna Sureda3, Alejandro Martín García-Sancho, MD, PhD6*, Mariana Bastos-Oreiro, MD, PhD4* and Pau Abrisqueta, MD, PhD1*

1Vall d’Hebron University Hospital, Barcelona, Spain
2Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
3Hospital Duran i Reynals, Instituto Catalán de Oncología, L'Hospitalet De Llobregat, Barcelona, Spain
4Gregorio Marañon General University Hospital, Madrid, Spain
5Oncology Data Science (ODysSey) Group, Vall d’Hebron Institute of Oncology (VHIO), BARCELONA, Spain
6Hematology Department, Hospital Clínico Universitario de Salamanca (CAUSA/IBSAL), Salamanca, Spain
7Hospital Universitario Virgen del Rocío, Sevilla, Spain
8Hematology Department, Hospital Clínico Universitario de Valencia, Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain
9Department of Hematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
10Hematology Department, Hospital de la Santa Creu i Sant Pau, BARCELONA, Spain
11Hospital Clinic, Barcelona, ESP
12Hematology Department, Hospital Dr. Negrín, Las Palmas de Gran Canaria, Spain
13Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, ESP
14Clinical Hematology Department, Hospital Germans Trias i Pujol, Badalona, Spain
15Department of Hematology Institute of Health Research Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain

1:15 PM

Paolo F Caimi, MD1, Christine Auberle, MD2, Krishna Goparaju, MD3, Firas Baidoun, MD4, Amanda F. Cashen, MD5 and Brian T. Hill, MD, PhD1

1Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
2Washington University School of Medicine, St. Louis
3University Hospitals- Case Western Reserve University, Cleveland, OH
4Division of Hematology and Medical Oncology, Mayo Clinic Florida, Westlake, OH
5Division of Oncology, Washington University School of Medicine, St. Louis, MO

*signifies non-member of ASH