-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

621.O2.6 621. Lymphomas: Translational—Molecular and Genetic: Genomic Characterization

Symposia: Lymphomas: Translational—Molecular and Genetic Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Translational Research, Lymphomas, non-Hodgkin lymphoma, genomics, Genetic Disorders, bioinformatics, B Cell lymphoma, Diseases, Lymphoid Malignancies, computational biology, Biological Processes, Technology and Procedures, molecular biology, omics technologies
Monday, December 12, 2022: 10:30 AM-12:00 PM
271-273 (Ernest N. Morial Convention Center)
Moderators:
Francesco Maura, M.D., Sylvester Comprehensive Cancer Center and Florence Nguyen Khac, Sorbonne Université, Pitié-Salpêtrière Hospital
Disclosures:
No relevant conflicts of interest to declare.
10:30 AM

Nicole Thomas, BSc1*, Kostiantyn Dreval1*, Daniela S. Gerhard, Ph.D.2*, Laura K Hilton, PhD3*, Jeremy S. Abramson, MD4, Nancy L. Bartlett, MD5, Jeffrey Bethony, PhD6*, Jay Bowen, MS7*, Anthony Bryan7*, Corey Casper, MD, MPH8*, Maureen Dyer, PhD9*, Manel Esteller, MD, PhD10*, Carlos Garcia-Prieto10*, Julie M Gastier-Foster, PhD11, Alina S. Gerrie, MD, MPH, FRCPC3, Bruno M. Grande, PhD12*, Timothy C. Greiner, MS, MD13, Nicholas B. Griner, PhD2*, Thomas G. Gross, MD, PhD14, Nancy Lee Harris, MD15, John D. Irvin, MD, PhD16*, Elaine S. Jaffe, MD17, Fabio Leal, MD, PhD18*, Jean Paul Martin, PhD16*, Marie-Reine Martin, MD16*, Sam M. Mbulaiteye, MBBChir, MPhil19*, Charles G. Mullighan, MBBS, MD20, Andrew J. Mungall, PhD21*, Karen Mungall, PhD21*, Constance Namirembe22*, Ariela Noy, MD23, Martin D Ogwang24*, Jackson Orem, MBChB, MMed, PhD22, German Ott, Prof.25*, Hilary Petrello7*, Steven J Reynolds26*, Steven H. Swerdlow, MD27, Alexandra Traverse-Glehen28*, Wyndham H. Wilson, MD, PhD29, Marco A. Marra21,30, Louis M. Staudt, MD, PhD29, David W. Scott, PhD, MD, FRACP, FRCPA3 and Ryan D. Morin3,21,31

1Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada
2Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
3Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
4Center for Lymphoma, Massachusetts General Hospital, Boston, MA
5Washington University School of Medicine, St. Louis, MO
6George Washington University, Washington, DC
7Biopathology Center, Nationwide Children's Hospital, Columbus, OH
8Access to Advanced Health Institute, Seattle, WA
9Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD
10Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain
11Department of Pathology and Laboratory Medicine, Nationwide Children’s Hospital and Ohio State University, Columbus, OH
12Sage Bionetworks, Seattle, WA
13Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
14Center for Global Health, National Cancer Institute, NIH, Rockville, MD
15Department of Pathology, Massachusetts General Hospital, Boston, MA
16Foundation for Burkitt Lymphoma Research, Geneva, Switzerland
17Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
18Programa de Oncovirologia, Instituto Nacional de Cancer, Rio de Janeiro, Brazil
19Division of Cancer Epidemiology and Genetics, National Cancer Institute, Silver Spring, MD
20Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
21Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
22Uganda Cancer Institute, Kampala, Uganda
23Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
24St. Mary’s Hospital, Gulu, Uganda
25Department of Clinical Pathology, Robert-bosch-Krankenhaus; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, DEU
26National Institute of Allergy and Infectious Diseases, Bethesda, MD
27Division of Hematopathology, UPMC, Pittsburgh, PA
28Service d'Anatomie pathologique, Université Lyon 1/Centre Hospitalier Lyon Sud, Pierre Bénite, France
29Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
30Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
31Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada

10:45 AM

Yuta Ito1,2*, Amira Marouf3*, Yasunori Kogure, MD, PhD1*, Junji Koya, MD, PhD1*, Mariko Tabata, MD1,4*, Yuki Saito, MD, PhD1,5*, Sumito Shingaki, MD, PhD1*, Mitsuhiro Yuasa, MD1,6*, Kentaro Yamaguchi, MD1,7*, Julie Bruneau, MD, PhD3,8*, Manon Vavasseur3*, Michaël Dussiot, PhD3*, Isabelle Andre, PhD9*, Akshay Joshi9*, Chantal Lagresle-Peyrou9*, Aude Magerus10*, Sammara Chaubard11*, David Lavergne, PhD11*, Emmanuel Bachy, MD, PhD12*, Erika Brunet, PhD13*, Virginie Fataccioli, PhD14*, Chantal Brouzes, MD15,16*, Camille Laurent, MD, PhD17*, Laurence De Leval, MD18, Alexandra Traverse-Glehen19*, Céline Bossard20*, Marie Parrens, MD, PhD21*, Véronique Meignin22*, Laure Philippe, MD23*, Julien Rossignol3,24*, Felipe Suarez, MD, PhD3,24, Jean-Marie Michot, MD25*, Olivier Tournilhac, MD, PhD26*, Christine Bole-Feysot, PhD27*, Patrick Nitschke28*, Bruno Tesson29*, Cécile Laurent29*, Thierry Jo Molina, MD, PhD3,8*, Vahid Asnafi, MD, PhD15,16*, Sachiko Tsukita30*, Koji Izutsu31,32*, Hiroaki Miyoshi, MD, PhD33*, Seiji Sakata34,35,36*, Akito Dobashi34,35,36*, Kengo Takeuchi34,35,36*, Koichi Ohshima, MD, PhD33*, Philippe Gaulard, MD, PhD14*, Arnaud Jaccard11*, Seishi Ogawa, MD, PhD37,38, Olivier Hermine, MD, PhD3,24, Keisuke Kataoka, MD, PhD1,7 and Lucile Couronne3,15*

1Division of Molecular Oncology, National Cancer Center Research Institute, Tokyo, Japan
2Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
3Laboratory of cellular and molecular mechanisms of hematological disorders and therapeutic implications, INSERM U1163, Imagine Institute, Paris City University, Paris, France
4Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
5Department of Gastroenterology, Keio University School of Medicine, Tokyo, Japan
6Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
7Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
8Pathology Department, Necker Children's Hospital, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
9Laboratory of Human Lympho Hematopoiesis, INSERM UMR 1163, Clinical Investigation Center (CIC) 1416-Institut Imagine, Paris City University, Paris, France
10Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Imagine Institute, INSERM UMR 1163, Paris City University, Paris, France
11Hematology department, Limoges University Hospital, Limoges, France
12Hematology Department, Hospices Civils de Lyon; Lymphoma Immuno-Biology (LIB) Team, Université Claude Bernard Lyon 1, Lyon, France
13Laboratory of the « Genome Dynamics in the Immune System », Équipe Labellisée La Ligue Contre Le Cancer, Paris City University, Université Paris Saclay, INSERM UMR 1163, Institut Imagine, Paris, Falkland Islands (The) [Malvinas]
14Pathology Department, Henri Mondor University Hospital, Assistance Publique des Hôpitaux de Paris, INSERM U955, Mondor Institute for Biomedical Research, Paris-Est Créteil University, Créteil, France
15Laboratory of Onco-Hematology, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France
16INSERM U1151, Institut Necker Enfants Malades (INEM), Paris, France
17Department of Pathology, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France; Cancer Research Center of Toulouse, INSERM UMR 1037, ERL5294 CNRS, Université Toulouse III-Paul-Sabatier, Toulouse, France
18Institute of Pathology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland
19Department of Pathology, Centre Hospitalier Lyon Sud and Université Claude Bernard Lyon-1, Pierre- Bénite, France
20Department of Pathology, CHU Nantes, Nantes, France; Université de Nantes, INSERM CRCINA, Nantes, France
21Department of Pathology, Bordeaux University Hospital, Bordeaux, France
22Pathology Department, Hôpital Saint Louis, Paris City University, Paris, France
23Department of Hematology, CH Annecy Genevois, Metz-Tessy, France
24Hematology Department, Necker Children's Hospital, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France
25Gustave Roussy, Département des Innovations Thérapeutiques et Essais Précoces, Université Paris-Saclay, Villejuif, France
26Department of Hematology, University Hospital of Clermont-Ferrand, Clermont Auvergne University, Clermont-Ferrand, France
27Genomics Core Facility, Institut Imagine-Structure Fédérative de Recherche Necker, INSERM U1163 et INSERM US24/CNRS UAR3633, Paris City University, Paris, France
28INSERM Unité Mixte de Recherche 1163, Bioinformatics Platform, Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France
29Bioinformatics department, CALYM / LYSARC, Paris, France
30Advanced Comprehensive Research Organization (ACRO), Teikyo University, Toko, Japan
31National Cancer Center Hospital, Tokyo, Japan
32Department of Hematology, Toranomon Hospital, Tokyo, Japan
33Department of Pathology, Kurume University School of Medicine, Kurume, Japan
34Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
35Department of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan
36Pathology Project for Molecular Targets, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
37Center for Hematology and Regenerative Medicine, Department of Medicine (MedH), Karolinska Institutet, Huddinge, Sweden
38Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan

11:00 AM

Zachary R Hunter, PhD1, Nickolas Tsakmaklis1*, Kris Richardson, PhD1*, Maria Luisa Guerrera, MD1*, Amanda Kofides1*, Xia Liu, MD1*, Shirong Liu, MD PhD1*, Alexa Canning1*, Manit Munshi, MS1*, Shayna Sarosiek, MD1, Catherine A. Flynn, NP1*, Andrew R. Branagan, MD2, Lian Xu, MS1*, Guang Yang, PhD1, Kirsten Meid, MPH1*, Joshua Gustine, MPH1*, Christopher J Patterson, MS, MPH1*, Kenneth C. Anderson, MD3, Nikhil C Munshi, MD, PhD3, Jorge J. Castillo, MD1 and Steven P Treon, MD, PhD1

1Bing Center for Waldenstrom's macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA
2Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA
3Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA

11:15 AM

Kerstin Wenzl, PhD1, Matthew E Stokes, PhD2*, Joseph P. Novak1*, Sana Khan1*, Melissa A. Hopper, BS, MS1, Jordan E. Krull1, Abigail Dropik1*, Vivekananda Sarangi3*, Raphael Mwangi, MS4*, Maria Ortiz, PhD5*, Nicholas Stong, PhD2*, C. Chris Huang, PhD6*, Matthew J. Maurer, DSc4, Lisa M. Rimsza, MD7, Brian K. Link, MD8, Susan L. Slager, PhD4, Yan Asmann, PhD9, Patrizia Mondello, MD, PhD, MSc1, Ryan D. Morin10, Stephen M. Ansell, MD, PhD1, Thomas M. Habermann, MD11, Andrew L. Feldman, MD12, Rebecca L. King, MD13, Grzegorz S. Nowakowski, MD1, James R. Cerhan, MD, PhD4, Anita K. Gandhi, PhD6 and Anne J. Novak, PhD1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, NJ
3Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
4Department of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN
5Informatics and Predictive Sciences, Bristol Myers Squibb, Seville, Spain
6Translational Medicine Hematology, Bristol Myers Squibb, Summit, NJ
7Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ
8Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa, Iowa City, IA
9Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL
10Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
11Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
12Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
13Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

11:30 AM

Beatriz García-Torre1*, Marta Kulis, PhD1*, Mònica Romo1*, Anna Vidal, PhD1*, Stella Charalampopoulou1*, Vicente Chapaprieta1*, Martí Duran-Ferrer1,2*, Ferran Nadeu, PhD1,2*, Cristina López, PhD1,2*, Guillem Clot, PhD1,2*, Eva Giné, MD, PhD1,2,3, Armando Lopez-Guillermo, MD1,2,3, Sílvia Beà, PhD3,4,5,6*, Dolors Colomer, PhD2,3,6,7*, Elías Campo, PhD MD2,3,8,9 and José I. Martín-Subero, PhD1,2,9,10*

1Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
2Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
3Hospital Clínic de Barcelona, Barcelona, Spain
4Molecular Pathology of Lymphoid Neoplasms Group, IDIBAPS, Barcelona, Spain
5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain
6University of Barcelona, Barcelona, Spain
7Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
8IDIBAPS, Barcelona, Spain
9Universitat de Barcelona, Barcelona, Spain
10Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

11:45 AM

Krysta M. Coyle, PhD1, Qurat Ul Ain Qureshi, BSc2*, Balwinder Ruprai, BSc2*, Tejdeep Kang2*, Laura K Hilton, PhD3*, Kostiantyn Dreval, PhD2,4*, Prasath Pararajalingam, BSc2*, Christopher K Rushton2*, Nicole Thomas2, Timothy E Audas, PhD2* and Ryan D. Morin4,5

1Department of Molecular Biology & Biochemistry, Simon Fraser University, Vancouver, BC, Canada
2Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada
3Centre for Lymphoid Cancer, BC Cancer Research Centre, Vancouver, BC, Canada
4Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
5Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada

*signifies non-member of ASH