Qing Deng, PhD^1*, Cem Meydan, PhD^2*, Priya Lakra, PhD^3*, Darko Barisic^4*, Christopher R Chin^5*, Estela Rojas-Neira^6*, Vida Ravanmehr^6*, Jared Henderson, PhD^1*, Panhong Gou^7*, Nader Kim El-Mallawany, MD^8*, Carl Allen, MD, PhD^9*, Branko Cuglievan, MD^10*, Francisco Vega, MD, PhD¹¹, Christopher E Mason, PhD^12*, Ari Melnick, MD¹³ and Michael R. Green, PhD¹⁴

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Medicine, Division of Hematology & Medical Oncology, Division of Hematology/Oncology, Dept. of Medicine, Weill Cornell Medical College, New York, NY
³Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX
⁴Weill Cornell Medicine, New York, NY
⁵Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY
⁶University of Texas MD Anderson Cancer Center, Houston, TX
⁷The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Section of Hematology/Oncology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX
⁹Department of Pediatrics, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX
¹⁰Division of Pediatric Hematology Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
¹²Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY
¹³Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY
¹⁴Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Friendswood, TX

Ja-Young Jang, PhD^1*, Heng Pan, PhD^2*, Maurizio Di Liberto, PhD^3*, Lapo Alinari, MD, PhD⁴, Giorgio Inghirami, MD^5*, Robert A. Baiocchi, MD, PhD⁴, Olivier Elemento, PhD^6*, Selina Chen-Kiang, PhD⁷ and Jihye Paik, PhD⁵

¹Weill Cornell Medicine, New york, NY
²Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY
³Department of Pathology and Laboratory Medicine, Meyer Cancer Center, Weill-Cornell Medical College, New York, NY
⁴Department of Internal Medicine, Division of Hematology, College of Medicine, The Ohio State University, Columbus, OH
⁵Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
⁶Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY
⁷Weil Cornell Medicine, Cornell University, New York, NY

Purushoth Ethiraj, PhD^1*, Carine Jaafar, PhD^1*, An-Ping Lin, MD^1*, Zhijun Qiu, PhD^1* and Ricardo Aguiar, MD, PhD²

¹University of Texas Health Science Center, San Antonio, TX
²University of Texas Health Sci. Ctr., San Antonio, TX

Gongwei Wu, PhD^1,2,3, Noriaki Yoshida, MD, PhD^1,4, Jihe Liu, PhD^5*, Xiaoyang Zhang, PhD^6,7,8*, Tayla B. Heavican-Foral, PhD⁹, Huiyun Liu^1*, Geoffrey M. Nelson^10*, Lu Yang, PhD^11*, Renee Chen^12*, Marcus Kenneth Jones^13*, Ran Xu, PhD^10,14, Ajit Johnson Nirmal^13*, Salvia Jain, MD^3,15, Catharine Leahy^14*, Kristen Lynn Jones, BS^13*, Kristen E. Stevenson, MS^16*, Wenchao Wu, PhD^17*, Abner Louissaint Jr., MD, PhD^10,18, Lydie Debaize, PhD¹⁹, Wing C. Chan, MD²⁰, Shannan Ho Sui^21*, Samuel Ng, MD, PhD^1*, Andrew L. Feldman, MD²², Matthew Meyerson, MD PhD^10,23,24*, Karen Adelman, PhD^25*, chun-Wei David Chen, PhD²⁶, Myles Brown, MD^3,17,27* and David M. Weinstock, MD^10,24,28,29

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA
³Harvard Medical School, Boston
⁴Radiation Effects Research Foundation, Hiroshima-Shi, Japan
⁵Bioinformatics Core, Harvard T.H. Chan School of Public Health, Boston
⁶Department of Medical Oncology, Dana Farber Cancer Institute, Boston
⁷Broad Institute of MIT and Harvard University, Cambridge
⁸Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City
⁹Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA
¹⁰Harvard Medical School, Boston, MA
¹¹Department of Systems Biology, Beckman Research Institute, City of Hope National Medical Center, Monrovia, CA
¹²Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA
¹³Dana-Farber Cancer Institute, Boston, MA
¹⁴Dana Farber Cancer Institute, Boston, MA
¹⁵Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA
¹⁶Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
¹⁷Department of Medical Oncology, Dana-Farber Cancer Institute, Boston
¹⁸Massachusetts General Hospital, Boston, MA
¹⁹Department of Medical Oncology, Dana-Farber Cancer Institiute, Boston, MA
²⁰City of Hope Medical Center, Duarte, CA
²¹Harvard School of Public Health, Boston, MA
²²Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
²³Broad Institute, Cambridge, MA
²⁴Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
²⁵Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA
²⁶Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA
²⁷Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston
²⁸Broad Institute of MIT and Harvard, Cambridge, MA
²⁹Merck Research Labs, Boston

Jaewoong Lee, PhD^1*, Kohei Kume, PhD^2*, Mark E. Robinson, PhD^1*, Ruifeng Sun, BS^1*, Ning Ma, Ph.D^3*, Zhengshan Chen, MD-PhD^4*, Gang Xiao, PhD^4*, Kadriye Nehir Cosgun, PhD^1*, Lai N. Chan, PhD¹, Etienne Leveille, MD¹, Lars Klemm^1*, Vivasvan Vykunta^5*, Brian Shy^5*, Huimin Geng, PhD⁶, Selina M. Luger, MD, FRCPC⁷, Mark R. Litzow, MD⁸, Alexander Marson, MD PhD^5*, Elisabeth Paietta, PhD⁹, Nagarajan Vaidehi, PhD^3*, Eric Meffre, PhD^1* and Markus Müschen, MD¹

¹Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, New Haven, CT
²Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, Duarte, CA
³Department of Computational and Quantitative Medicine, City of Hope Comprehensive Cancer Center, Duarte, CA
⁴Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA
⁵Department of Medicine, University of California, San Francisco, San Francisco, CA
⁶Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
⁷Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
⁸Division of Hematology, Mayo Clinic, Rochester, MN
⁹Cancer Center, Montefiore Medical Center, Bronx, NY

Atish Kizhakeyil, PhD^1*, Sreejoyee Ghosh^2*, Estela Rojas-Neira^1*, Qing Deng, PhD^3*, Jared Henderson, PhD^3*, Jordan Showell^1*, Ari Melnick, MD⁴, Wendy Béguelin, PhD⁵, Francisco Vega, MD, PhD⁶, Loretta J. Nastoupil, MD⁷ and Michael R. Green, PhD⁸

¹University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY
⁵Weill Cornell Medical College, New York, NY
⁶Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
⁸Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Friendswood, TX