Shuchi Agrawal Singh, PhD^1,2,3, Jaana Bagri^4*, George Giotopoulos, PhD^2,5*, Eshwar Meduri, PhD^2,3*, Shubha Anad^6*, Sarah J. Horton, PhD^2,3*, Daniel Sasca, MD^7*, Haiyang Yun, PhD^2*, Anthony Whetton, PhD^8* and Brian Huntly, MB ChB, FRCPath, FMedSci, PhD⁹

¹Cambridge Institute for Medical Research, Cambridge Biomedical Campus, Cambridge, United Kingdom
²Department of Haematology, University of Cambridge, Cambridge, United Kingdom
³Wellcome - MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom
⁴Department of Hematology, Cambridge Stem Cell Institute, Cambridge, GBR
⁵Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom
⁶University of Cambridge, Cambridge, GBR
⁷Department of Hematology, Medical Oncology and Pneumology, University Medical Center of Mainz, Mainz, Germany
⁸Stem Cell & Leukaemia Proteomics Lab, Manchester, GBR
⁹Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, ENG, United Kingdom

Karina Hamamoto, PhD^1*, Qian Lai^2,3*, Huacheng Luo, PhD¹, Julia Lesperance^1*, Zachary Zaroogian^4*, Jie Zha, MD, PhD^5*, Yi Qiu, PhD⁶, Olga A Guryanova, MD, PhD⁷, Bing Xu, MD, PhD^8* and Suming Huang, PhD⁹

¹Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA
²Department of Pediatrics, Pennsylvania State University Hershey College of Medicine, Hershey, PA
³Department of Hematology, The First Affiliated Hospital of Xiamen University, Xiamen, China
⁴University of Florida, Gainesville, FL
⁵Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China
⁶Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA
⁷Department Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, FL
⁸Department of Hematology, The first Affiliated Hosptial of Xiamen University, Xiamen, China
⁹Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA

Gandhar Datar, BS¹, Archish Anand, BS^1*, Marwa Sadek, MBBS, MS^2*, Christina Dollinger, BS, MA^1*, English Laserna, BS^3*, Lorenzo Brunetti, MD, PhD^4*, Nidhi Sahni, PhD^5*, Joshua Riback, PhD^1* and Margaret A. Goodell, PhD¹

¹Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX
²School of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Integrative Physiology, Baylor College of Medicine, Houston, TX
⁴Department of Molecular and Clinical Sciences, University Hospital of Ancona, Ancona, PG, Italy
⁵Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX

Chen-Jen Hsu, MSc^1*, Tina M. M Schnoeder, PhD^1*, Theresa Eifert, MSc^1*, Qirui Zhang, PhD^1*, Oliver Meers, MSc^2*, David Corujo, PhD^2*, Maximilian Lassi, PhD^3*, Raffaele Teperino, PhD^3*, Stefan Dimitrov, PhD^4*, Holger Bierhoff, PhD^5,6*, Björn von Eyss, PhD^5*, Florian Perner, MD¹, Marcus Buschbeck, PhD^2* and Florian H. Heidel, MD^1,5

¹Klinik und Poliklinik für Innere Medizin C, Universitätsklinikum Greifswald, Greifswald, Germany
²Josep Carreras Leukemia Research Institute, Badalona-Barcelona, Spain
³Institute of Experimental Genetics, Helmholtz Zentrum, Munich, Germany
⁴Institute for Advanced Biosciences, Universite´ de Grenoble Alpes, Grenoble, France
⁵Fritz-Lipmann Institute, Leibniz Institute on Aging, Jena, Germany
⁶Institute of Biochemistry and Biophysics, Friedrich-Schiller University, Jena, Germany

Takayasu Kato, MD, PhD^1,2*, Yusuke Kiyoki, MD^3,4*, Sakura Kito^3*, Takashi Matsuzaka, PhD^5,6*, Shin Morioka, PhD^7,8*, Junko Sasaki, PhD^7,8,9*, Tatsuhiro Sakamoto, MD, PhD^1*, Hidekazu Nishikii, MD, PhD¹, Naoshi Obara, MD, PhD^1*, Mamiko Sakata-Yanagimoto, MD, PhD^1,10*, Takehiko Sasaki, PhD^7,9*, Hitoshi Shimano, MD, PhD^6* and Shigeru Chiba, MD, PhD¹

¹Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
²Department of Laboratory Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
³Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
⁴Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan
⁵Division of Energy Metabolism, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan
⁶Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
⁷Department of Lipid Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⁸Department of Biochemical Pathophysiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
⁹Department of Cellular and Molecular Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
¹⁰Division of Advanced Hemato-Oncology, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan

Huacheng Luo, PhD¹, Karina Hamamoto, PhD^1*, Julia Lesperance^1*, Yi Qiu, PhD² and Suming Huang, PhD³

¹Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA
²Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA
³Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA