-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

508.O2.6 508. Bone Marrow Failure: Acquired: Clinical Studies

Symposia: Bone Marrow Failure: Acquired Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Acquired Marrow Failure Syndromes, Biological therapies, clinical trials, adult, Clinical Practice (Health Services and Quality), Bone Marrow Failure Syndromes, Translational Research, CHIP, Aplastic Anemia, Clinical Research, Paroxysmal Nocturnal Hemoglobinuria, drug development, pediatric, Diseases, Therapies, Immunotherapy, Adverse Events, young adult , Monoclonal Antibody Therapy, Biological Processes, Study Population, Human
Saturday, December 10, 2022: 4:00 PM-5:30 PM
260-262 (Ernest N. Morial Convention Center)
Bruno Fattizzo, MD, and Pedro H. Prata, MD, Hôpital Saint Louis
No relevant conflicts of interest to declare.
This session includes oral presentations on clinical research and clinical trials on acquired bone marrow failure syndromes, including aplastic anemia and paroxysmal nocturnal hemoglobinuria.
4:00 PM

Akiko Shimamura, MD, PhD1*, Alexey Maschan, MD2*, Carolyn Bennett, MD3, Jason E Farrar, MD4, Sujith Samarasinghe, PhD, FRCPath5*, Brigitte Strahm, MD6*, Winfred C. Wang, MD7, Adrianna Vlachos, MD8, Charlotte M. Niemeyer6, Timothy S. Olson, MD, PhD9, Denise D'Alessio, MBA10*, Elise Burmeister Getz, PhD11*, Tomasz Lawniczek, MD12, Yunnan Xu, PhD10* and David A. Williams, MD1

1Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
2Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
3Aflac Cancer and Blood Disorder Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA
4University of Arkansas For Medical Sciences, Little Rock, AR
5Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, United Kingdom
6Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
7Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
8Division of Hematology/Oncology and Cellular Therapy, Cohen Children's Medical Center, Northwell Health, New York, NY
9Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
10Novartis Pharmaceuticals Corporation, East Hanover, NJ
11Novartis Institutes for BioMedical Research (NIBR), Emeryville, CA
12Novartis Pharma AG, Basel, Switzerland

4:15 PM

Joseph H Oved, MD1, Yash Shah2*, Yimei Li, PhD3*, Dimitri S. Monos, PhD4*, Daria V. Babushok, MD5, Minjie Luo, Ph.D.6*, Marilyn M. Li, MD7* and Timothy S. Olson, MD, PhD8

1Transplantation and Cellular Therapy, Memorial Sloan Kettering Cancer Center (MSK Kids), New York, NY
2Children's Hospital of Philadelphia, Philadelphia, PA
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
4Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA
5Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Merion Station, PA
6Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA
7Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
8Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA

4:30 PM

Yoshitaka Zaimoku, MD, PhD1,2, Hiroki Mizumaki, MD, PhD2*, Takeshi Yoroidaka, MD, PhD2*, Noriharu Nakagawa, MD, PhD2*, Tatsuya Imi, MD, PhD2*, Hiroyuki Maruyama, MD, PhD2*, Mikoto Tanabe, MD, PhD2*, Noriaki Tsuji, MD, PhD2*, Ryota Urushihara, MD2*, Kohei Hosokawa, MD, PhD2, Takamasa Katagiri, PhD2*, Hiroyuki Takamatsu, MD, PhD2, Ken Ishiyama, MD, PhD2, Hirohito Yamazaki, MD, PhD2*, Toshihiro Miyamoto, MD, PhD2 and Shinji Nakao, MD, PhD2

1Department of Infection Control and Prevention, Kanazawa University Hospital, Kanazawa, Japan
2Department of Hematology, Kanazawa University, Kanazawa, Japan

4:45 PM

Srilatha Dasari, MD1*, William Tse, MD2 and Jiasheng Wang, MD3

1Department of Medicine, MetroHealth Medical Center, Cleveland, OH
2Department of Hematology and Oncology, The MetroHealth System Campus of Case Western Reserve University, Cleveland, OH
3Department of Hematology and Oncology, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH

5:00 PM

Hui Liu1*, Linghui Xia2*, Jianyu Weng3*, Fengkui Zhang4*, Chuan He5*, Sujun Gao, PhD6*, Jinsong Jia7*, Alice C. Chang8*, Pontus Lundberg9*, Camelia S. Sima8*, Jane Shi10*, Zhenyu Xiao10*, Yuchen Zhang11*, Zilu Zhang10* and Rong Fu1*

1Department of hematology, Tianjin Medical University General Hospital, Tianjin, China
2Wuhan Union Hospital, Wuhan, China
3Guangdong Provincial People’s Hospital, Guangdong, China
4Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, China
5West China Hospital, Sichuan University, Chengdu, China
6Department of Hematology, The First Hospital of Jilin University, Changchun, China
7Peking University People's Hospital, Beijing, China
8Genentech, Inc., South San Francisco, CA
9F. Hoffmann-La Roche Ltd, Basel, Switzerland
10Roche Product Development, Shanghai, China
11China Innovation Center of Roche, Shanghai, China

5:15 PM

Peter J. Browett1, Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP2, Rosario Notaro, MD3*, Masayo Ogawa, MD4*, Antonio M Risitano, MD, PhD5, Ji Yu4* and Jong Wook Lee, M.D., Ph.D.6

1University of Auckland, Auckland, New Zealand
2King's College Hospital - NHS Foundation Trust, NIHR Wellcome King’s Clinical Research Facility, London and King’s College London, London, United Kingdom
3Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
4Alexion, AstraZeneca Rare Disease, Boston, MA
5Federico II University, Naples, Italy
6Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)

*signifies non-member of ASH