Michael J. Kovacs, MD¹, Philip S. Wells, MD, MSc, FRCPC², Marc A. Rodger, MD, MSc³, Marc Carrier, MD, MSc, FRCPC⁴, Erik Yeo, MD, FACP, FRCPC⁵, Judy A Kovacs, RN^6* and Alejandro Lazo-Langner, MD, MSc, FRCPC⁷

¹Department of Medicine, Division of Hematology, University of Western Ontario, London, ON, Canada
²Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
³Department of Medicine, McGill University, Montreal, Canada
⁴Department of Medicine, University of Ottawa, Ottawa, ON, Canada
⁵University Health Network, University of Toronto, Toronto, ON, Canada
⁶Lawson Health Research Institute, London, ON, Canada
⁷Division of Hematology, Department of Medicine, University of western Ontario, London, ON, Canada

Michael A Pfeffer, MBBS¹, Helen Vu^2*, Tia CL Kohs^2*, Jenny Wang, PhD^2*, Christina U Lorentz, PhD^2,3*, Erik I Tucker, PhD^2,3, Sven R Olson, MD¹, Thomas G Deloughery, MD¹, Monica T Hinds^2*, Owen JT McCarty, PhD^2* and Joseph J Shatzel, MD^1,2

¹Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR
²Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR
³Aronora, Inc., Portland, OR

Florian Moik^1,2*, Jakob Riedl^3*, Dominik Barth^1*, Wei-Shin Evelyn Chan^2*, Sarah Wiedemann^4*, Christoph Höller^5*, Thorsten Fuereder^6*, Philipp Jost^1*, Ingrid Pabinger, MD², Matthias Preusser^6,7* and Cihan Ay, MD^2*

¹Department of Internal Medicine, Division of Oncology, Medical University of Graz, Graz, Austria
²Department of Medicine I, Clinical Divison of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
³Department of Internal Medicine, Division of Oncology, Medical University of Graz, Graz, AUT
⁴Department of Medicine I, Clinical Divison of Hematology and Hemostaseology, Medical University of Vienna, Vienna, AUT
⁵Department of Dermatology, Medical University of Vienna, Vienna, Austria
⁶Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, AUT
⁷Christian Doppler Laboratory for Personalized Immunotherapy, Medical University of Vienna, Vienna, Austria

Avi Leader, MD^1,2*, Sarah Elitzur, MD^1,3*, Baruch Gavrieli^1*, Henri M.H. Spronk, PhD^4,5, Magdolna Nagy^4*, Rene Van Oerle, PhD^4*, Galia Spectre, MD, PhD^1,2*, Shai Shimony, MD^1,6,7*, Yakir Moshe, MD, PhD^1,8*, Roaya Mahajna, B.Sc.^9*, Gil Gilad, MD^1,9*, Galia Avrahami, MD^1,9*, Shai Izraeli, MD^1,10, Pia Raanani, MD^1,6, Shlomit Barzilai-Birenboim, MD^1,9* and Ofir Wolach, MD^1,2*

¹Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
²Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel
³Department of Pediatric Hematology-Oncology, Schneider Childen's Medical Center of Israel, Petah Tikva, Israel
⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands
⁵Thrombosis Expertise Center, Heart+Vascular Center, Maastricht University Medical Center+, Maastricht, Netherlands
⁶Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah-Tikva, Israel
⁷Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁸BMT Unit, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⁹Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
¹⁰Department of Pediatric Hematology Oncology, Schneider Children Medical Center of Israel, Petach Tikva, Israel

Florian Moik^1,2*, Simon Kraler^3*, Fabrizio Montecucco^4*, Luca Liberale^4*, Stephan Nopp^2*, Cornelia Englisch^2*, Tetiana Lapikova-Bryhinska^3*, Alexander Akhmedov^3*, Arnold von Eckardstein^5*, Florian A. Wenzl^3*, Ingrid Pabinger, MD⁶, Thomas F. Lüscher^7,8* and Cihan Ay, MD^2*

¹Department of Internal Medicine, Division of Oncology, Medical University of Graz, Graz, Austria
²Department of Medicine I, Clinical Divison of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
³Center for Molecular Cardiology, University of Zürich, Zurich, Switzerland
⁴First Clinic of Internal Medicine, Department of Internal Medicine; IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascular Network, University of Genoa, Genoa, Italy
⁵Institute of Clinical Chemistry, University Hospital of Zurich, Zurich, Switzerland
⁶Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
⁷Heart Division, Royal Brompton & Harefield Hospitals, Imperial College and Kings College London, London, United Kingdom
⁸Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland

Kimberly Snow Caroti, PharmD^1*, Khaled Abdelgawwad, MSc, MBA^2*, George Psaroudakis, PhD^3*, Marcela Rivera, PhD^4*, Gunnar Brobert, PhD^3*, Alexander T Cohen, MBBS MSc MD FRACP FESC^5*, Alok A Khorana, MD⁶, Cecilia Becattini, MD^7*, Agnes Y. Lee, MD, MSc⁸, Anders Ekbom, MB, MD, PhD^9*, Marc Carrier, MD, MSc¹⁰ and Craig I. Coleman, PharmD¹¹

¹Hartford Hospital, Evidence-Based Practice Center, Hartford, CT
²Thrombosis and Opthalmology, Bayer AG, Berlin, Germany
³Bayer AG, Berlin, Germany
⁴Bayer AG, Berlin, AL, Germany
⁵Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
⁶Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
⁷Internal Vascular and Emergency Medicine Stroke Unit, University of Perugia, Perugia, Italy
⁸University of British Columbia, Vancouver, BC, Canada
⁹Unit of Clinical Epidemiology, Department of Medicine, Karolinska Institute, Solna, Sweden
¹⁰Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada
¹¹School of Pharmacy, University of Connecticut, WEST SUFFIELD, CT