Clay T Cohen, MD¹, Mark Zobeck, MD, MPH^1* and Jacquelyn M. Powers, MD²

¹Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, TX
²Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX

Margaret V. Ragni, MD, MPH¹, Scott Rothenberger, PhD^2*, Robert Feldman, MS^2*, Danielle Nance, MD^3*, Andrew D Leavitt, MD⁴, Lynn Malec, MD⁵, Robert F. Sidonio, Jr., MD, MSc^6,7, Eric H. Kraut, MD⁸, Joseph L Lasky III, MD^9*, Claire S. Philipp, MD¹⁰, Dana E. Angelini, MD¹¹, Rajiv K. Pruthi, M.B.B.S¹², Nina Hwang, MD^13*, Allison P. Wheeler, MD¹⁴, Roshni Kulkarni¹⁵, Craig D. Seaman¹⁶, Frederico Xavier, MD, MS¹⁷, Nicoletta C Machin, DO, MS¹, Michael Meyer, MS^18*, Daniel Bellissimo, PhD^19*, Kenneth J. Smith, MD^20*, Elizabeth P. Merricks, PhD^21*, Timothy C. Nichols, MD, PhD²¹, Dana Ivanco^22*, Deborah Vehec, MSN, RN^22*, Glory Koerbel, MPPM, MSN, RN^2* and Andrew D. Althouse, PhD^2*

¹University of Pittsburgh and Hemophilia Center of Western Pennsylvania, Pittsburgh, PA
²Center for Research on Health Care Data Center, University of Pittsburgh, Pittsburgh, PA
³Banner MD Anderson Cancer Center, Gilbert, AZ
⁴Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
⁵Blood Research Institute, Versiti, Milwaukee, WI
⁶Emory University, Aflac Cancer and Blood Disorders, ATLANTA, GA
⁷Aflac Cancer and Blood Disorders Center, Emory University, Decatur, GA
⁸Division of Hematology, The Ohio State University, Columbus, OH
⁹Cure 4 The Kids Foundation, Las Vegas, NV
¹⁰Medicine, Rutgers University, New Brunswick, NJ
¹¹Taussig Cancer Institute, Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Avon Lake, OH
¹²Division of Hematology, Mayo Clinic, Rochester, MN
¹³CHOC Children's Hospital, Orange County, Center for Inherited Blood Disorders (CIBD), Orange, CA
¹⁴Vanderbilt University Medical Center, Nashville, TN
¹⁵Center for Bleeding and Clotting Disorders, Michigan State University, East Lansing, MI
¹⁶University of Pittsburgh and Hemophilia Center of Western Pennsylvania, Warrendale, PA
¹⁷Children's Hospital of Pittsburgh, University of Pittsburgh and Hemophilia Center of Western PA, Pittsburgh, PA
¹⁸Vitalant Coagulation Laboratory, PIttsburgh, PA
¹⁹Clinical Genomics Laboratory, University of Pittsburgh, Pittsburgh, PA
²⁰University of Pittsburgh School of Medicine, Pittsburgh, PA
²¹Department of Pathology and Laboratory Medicine and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC
²²Hemophilia Center of Western PA, Pittsburgh, PA

Eva Kempers, BSc^1*, Calvin B. van Kwawegen, MD^2*, Joke de Meris^3*, Saskia E.M. Schols, MD, PhD^4,5*, Paula F. Ypma, MD, PhD^6*, Floor C.J.I. Moenen^7*, Lize F.D. Van Vulpen, MD, PhD^8*, Michiel Coppens^9,10*, Johanna G. van der Bom, MD, PhD^11*, Karin Fijnvandraat, MD^12,13*, Karina Meijer, MD, PhD¹⁴, Jeroen C.J. Eikenboom, MD, PhD¹⁵, Samantha C. Gouw, MD, PhD^16*, Frank W.G. Leebeek, MD, PhD² and Marieke J.H.A. Kruip, MD, PhD^2*

¹Dept. of Hematology, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, AL, Netherlands
²Dept. of Hematology, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands
³Netherlands Hemophilia Society, Zoetermeer, Netherlands
⁴Department of Hematology, Radboudumc, Nijmegen, Netherlands
⁵Hemophilia Treatment Center, Nijmegen, Eindhoven, Maastricht, Netherlands
⁶Department of Hematology, Haga Hospital, The Hague, Netherlands
⁷Department of Internal Medicine - Hematology, Maastricht University Medical Center, Maastricht, Netherlands
⁸Benign Hematology Center, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
⁹Amsterdam UMC location, University of Amsterdam, Vascular Medicine, Amsterdam, Netherlands
¹⁰Amsterdam Cardiovascular Sciences, Pulmonary Hypertension & Thrombosis, Amsterdam, Netherlands
¹¹Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
¹²Dept. of Plasma Proteins, Sanquin Research, Amsterdam, Amsterdam, Netherlands
¹³Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
¹⁴Dept. of Hematology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
¹⁵Dept. of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, Netherlands
¹⁶Department of Pediatric Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands

Zain M Virk, MD^1*, Ellen Zhang, BA^2*, Josanna Rodriguez-Lopez, MD^3*, Alison Witkin, MD^3*, Alexandra Wong, MD^3*, Jay Luther, MD^4*, Angela Lin, MD^5*, Mingming Ning, MD^6*, Eric F. Grabowski, MD, DSc⁷, Eric Holbrook, MD^8* and Hanny Al-Samkari, MD⁹

¹Vanderbilt University Medical Center, Nashville, TN
²Harvard Medical School, Boston, MA
³Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA
⁴Division of Gastroenterology and Hepatology, Massachusetts General Hospital, Boston, MA
⁵Department of Pediatrics, Massachusetts General Hospital, Boston, MA
⁶Department of Neurology, Massachusetts General Hospital, Boston, MA
⁷Cardiovascular Thrombosis Laboratory, Massachusetts General Hospital, Boston, MA
⁸Division of Rhinology, Massachusetts Eye and Ear Institute, Boston, MA
⁹Division of Hematology Oncology, Massachusetts General Hospital, Cambridge, MA

ErinMarie O. Kimbrough, MD¹, Ariana Mooradian, MD, MPH¹, Michael G. Heckman, MS^2*, Zhongwei Peng^3*, Emily B. Butts, MD^4*, Denise A. Gococo-Benore, MD^4*, Zaid Abdel Rahman, MD⁵, Ewa Wysokinska, MD⁶, Gretchen Schaef Johns, MD⁷ and James M. Foran, MD⁸

¹Division of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, FL
²Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL
³Division of Biomedical Statistics and Informatics, Mayo Clinic Florida, Jacksonville, FL
⁴Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL
⁵Division of Hematology and Medical Oncology, Mayo Clinic-Jacksonville, Fargo, ND
⁶Mayo Clinic, Jacksonville, FL
⁷Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL
⁸Division of Hematology/Oncology and Blood and Marrow Transplanation and Cellular Therapy, Mayo Clinic, Jacksonville, FL

Miguel López Esteban^1*, Marta Moreno Carbonell^2*, Jesus Viñas Soler^2*, Jose L. Diez Martin, MD PhD^3,4,5*, Patricia Duque, MD^6* and Cristina Pascual Izquierdo, MD, PhD^2,7*

¹Hematology, Hospital Universitario Gregorio Marañon, Madrid, AL, Spain
²Hematology, Hospital Universitario Gregorio Marañón, Madrid, Spain
³Department of Medicine, School of Medicine, Complutense University of Madrid, Madrid, Spain
⁴Hematology, Hospital Universitario Gregorio Marañon, Madrid, Spain
⁵Gregorio Maranon Health Research Institute (IiSGM), Madrid, Spain
⁶Department of Anesthesiology, Hospital Universitario Gregorio Marañon, Madrid, Spain
⁷Hematology Department, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain