-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

301.O2.6 301. Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational: Mechanistic Insights That Suggest Novel Diagnostic or Therapeutic Strategies

Symposia: Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Fundamental Science, clinical trials, Bleeding and Clotting, bleeding disorders, autoimmune disorders, Biological therapies, Anticoagulant Drugs, adult, Translational Research, Non-Biological therapies, assays, elderly, Clinical Research, platelet disorders, Chemotherapy, thromboembolism, pediatric, Diseases, thrombocytopenias, Immune Disorders, thrombotic disorders, Therapies, Lymphoid Malignancies, young adult , Adverse Events, metabolism, Biological Processes, Technology and Procedures, molecular biology, Study Population, Human, Animal model, omics technologies
Monday, December 12, 2022: 2:45 PM-4:15 PM
353-355 (Ernest N. Morial Convention Center)
Freda H. Passam, MD, PhD, St. George Hospital and Claudia Lorena Buitrago, PhD, The Rockefeller University
No relevant conflicts of interest to declare.
2:45 PM

Adam Kanack, PhD1*, Rachel Leger, BAE1*, Abdulrahman Saadalla1*, Nahla Heikal, M.D.1*, Dong Chen, M.D., Ph.D2, David Garcia3, Rajiv K. Pruthi, M.B.B.S4 and Anand Padmanabhan, M.B.B.S., Ph.D.1*

1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
2Mayo Clinic, Rochester, MN
3University of Washington, Seattle, WA
4Division of Hematology, Mayo Clinic, Rochester, MN

3:00 PM

Shravani Prakhya, MS1*, Linda Omali1*, Joshua Lykins1*, Daniëlle Coenen, PhD1*, Hemendra Vekaria, PhD2* and Sidney W Whiteheart, PhD1

1Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY
2Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY

3:15 PM

Vishwanath Jha, PhD1*, Tripti Kumari2*, Bei Xiong3*, Kyungho Kim, PhD4*, Jingzhi Wang, Ph.D5*, Gavriel Brown, BS6*, Nathan Asquith, PhD7*, John Gallagher, BS6*, Lillian Asherman8*, Yanyan Bai9*, Xiaoping Du, MD, PhD10*, Jeong-Ki Min11*, Babak Razani12*, Joseph E. Italiano Jr., Ph.D.13, Jin-Moo Lee, MD, PhD14* and Jaehyung Cho, PhD15

1Division of Hematology, Washington University in St. Louis, SAINT LOUIS, MO
2Washington University in St. Louis, St. Louis, MO
3Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China
4Department of Pharmacology, University of Illinois At Chicago, Chicago, IL
5Washington University, St. Louis
6Washington University School of Medicine, Washington University, Saint Louis, MO
7Boston Childrens Hospital, Boston, MA
8Washington University, Saint Louis, MO
9University of Illinois at Chicago, Chicago, IL
10Department of Pharmacology, The University of Illinois, Chicago, IL
115Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea, Republic of (South)
12Department of Pathology and Immunology, Washington university, St. Louis, MO
13Department of Medicine, Harvard Medical School and Boston Childrens Hospital, Boston, MA
14Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO
15Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO

3:30 PM

Sergey Zaytsev, PhD1*, Hyunsook Ahn, MS1*, M. Anna Kowalska, PhD2, Rodney Camire, PhD1,3*, Douglas B. Cines, MD4, Mortimer Poncz, MD1,3* and Victoria Stepanova, PhD3*

1Children's Hospital of Philadelphia, Philadelphia, PA
2Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
3Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA
4University of Pennsylvania PSOM, Philadelphia, PA

3:45 PM

Raoul Santiago, MD, MSc1,2, Marie-Claude Pelland-Marcotte, MD, PhD1,2*, Arnaud Droit, PhD1*, Jeyani George Clement, BSc1*, Lara Herrmann, MSc1*, Meredith Michelle Rémy, MBBS3*, Yan Ma, BSc1*, Virgile Raufaste-Cazavieille, MSc1*, Jessica Liu, MBBS4*, Charles Joly-Beauparlant, PhD1*, Mickael Leclercq, PhD1*, Camille Jimenez-Cortes, MSc4*, Thomas Sontag, BSc4*, Maxime Caron, PhD4*, Pascal St-Onge, MSc4*, Sylvie Langlois, MSc4*, Victoria Koch, BA5*, Daniel Sinnett, PhD4,6*, Lewis B. Silverman, MD5 and Thai Hoa Tran, MD4,6

1Centre de recherche du CHU de Québec, Université Laval, Quebec City, QC, Canada
2CHU de Québec, Université Laval, Department de Pédiatrie, Quebec City, QC, Canada
3Faculté de Médecine, Université Laval, Quebec City, QC, Canada
4Centre de recherche du CHU Sainte-Justine, CHU Sainte-Justine, Montréal, QC, Canada
5Dana-Farber Cancer Institute and Boston Children's Hospital, Department of Pediatric Oncology, Boston, MA
6Centre de cancérologie Charles-Bruneau, Département de pédiatrie, CHU Sainte-Justine, Université de Montréal, Montréal, QC, Canada

4:00 PM

Yuchen Gao1*, Ying Chi2*, Yunfei Chen, MD2*, Hui Yuan Li2*, Wentian Wang, PhD2*, Wenting Zheng2*, Ping Zhu, PhD2*, Jinying An3*, Yanan Duan3*, Ting Sun, MD2*, Liu Xiaofan, MD4*, Feng Xue, MD4*, Wei Liu2*, Rongfeng Fu, MD4*, Zhibo Han2*, Yingchi Zhang, PhD2*, Renchi Yang, MD2*, Cheng Tao, MD, PhD2*, Jun Wei2*, Xiaomin Zhang3* and Lei Zhang, MD4*

1State Key Laboratory of Experimental Hematology, Institute of Hematology and Blo, Tianjin, China
2State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
3Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, CHN
4CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China

*signifies non-member of ASH