-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

641. Chronic Lymphocytic Leukemias: Basic and Translational: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Monday, December 13, 2021: 6:00 PM-8:00 PM
Hall B5, Level 1, Building B (Georgia World Congress Center)

Shih-Shih Chen, PhD1, Jacqueline Barrientos, MD, MS1, Xiao-Jie Yan, MD PhD1*, Uwe Wirtz2*, Edith Szafer-Glusman, PhD2*, Kanti R Rai1 and Nicholas Chiorazzi, MD3

1Karches Center for Oncology Research, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY
2AbbVie Inc, Sunnyvale, CA
3Karches Center for Oncology Research, The Feinstein Institute For Medical Research, Manhasset, NY

Anna Carbó-Meix, PhD1*, Francesca Guijarro, MD2*, Luojun Wang, MD3*, Romina Royo4*, Isabel Granada, PhD5*, José Tomás Navarro, MD6*, Blanca Espinet, PhD7*, Gustavo Tapia8*, Fina Climent, MD9*, Mariana Fernández-Caballero10*, Esmeralda De la Banda, MD11*, Janilson Do Nascimento12*, Alberto Pineda13*, Dolors Vela, MD14*, María Rozman, MD3*, Marta Aymerich, MD1,3*, Estella Matutes, MD, PhD3*, Sílvia Beà, PhD1,3,15,16*, Dolors Costa, MD3*, Ferran Nadeu, PhD1,15* and Elías Campo1,3,15,16

1Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
2Hospital Clínic de Barcelona, IDIBAPS, Hematopathology department, Barcelona, Spain
3Hospital Clínic de Barcelona, Barcelona, Spain
4Barcelona Supercomputing Center (BSC), Barcelona, Spain
5ICO-Hospital Germans Trias i Pujol. Josep Carreras Research Institute. Universitat Autònoma de Barcelona, Badalona, Spain
6Department of Hematology-Laboratory, Institut Català d'Oncologia, Barcelona, Spain
7Laboratoris de Citologia Hematològica i Citogenètica, Servei de Patologia, Hospital del Mar. GRETNHE- Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain
8Department of Pathology, Hospital Germans Trias i Pujol, Barcelona, Spain
9Pathology Department, Hospital Universitari de Bellvitge, IDIBELL, L'Hospitalet De Llobregat, Spain
10Hospital Municipal de Badalona, Badalona, Spain
11Laboratory of Hematology, Hospital Universitari Bellvitge, IDIBELL, Barcelona, Spain
12Hospital Joan XXIII, Institut Català d'Oncologia, Tarragona, Spain
13Fundació Hospital de l'Esperit Sant, Badalona, Spain
14Hematologia Clínica, Hospital General de Granollers, Granollers, Spain
15Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
16Universitat de Barcelona, Barcelona, Spain

Charis E Teh, PhD1,2*, Tania Tan, B.Sc1*, Marie Trussart, PhD1,2*, Mengxiao Luo, MSc1*, Rachel Thijssen, PhD2*, Andrew W Roberts, PhD, MBBS1,2,3,4, David C.S. Huang, MBBS, PhD1,2*, Terence Speed, PhD1,2*, Mary Ann Anderson, MBBS, FRACP, FRCPA1,2,3,4 and Daniel Gray, PhD1,2*

1The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia
2University of Melbourne, Melbourne, Australia
3The Royal Melbourne Hospital, Melbourne, Australia
4Peter MacCallum Cancer Centre, Melbourne, Australia

Daniel Friedman, PhD1*, Antony Long, BSc2*, Piers EM Patten, MB, ChB, FRCP, FRCPath, PhD3,4 and Robbert Hoogeboom, PhD3*

1Comprehensive Cancer Centre, King's College London, London, ENG, United Kingdom
2King's College Hospital, London, United Kingdom
3Comprehensive Cancer Centre, King's College London, London, United Kingdom
4King’s College Hospital, London, United Kingdom

Hui Jin, MD1*, Zijuan Wu1*, Lei Fan2*, Luqiao Wang1*, Xueying Lu1*, Danling Gu1*, Lei Cao1* and Jianyong Li2

1Department of Hematology, Pukou CLL Center, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
2Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China

Martina Cusan1*, Meiling Jin2*, Bo Zhang, MD, PhD3, Mike Fernandez2*, Aijun Liao2,4*, Lu Yang, PhD5*, Yiming Wu6*, Prajish Iyer, PhD7*, Kevyn Hart2*, Catherine Gutierrez8, Jeremy Stark9*, Teresa V. Bowman10*, Catherine J. Wu, MD11,12,13,14, Ren-Jang Lin, PhD15* and Lili Wang, MD-PhD2

1Beckman Research Insititute - City Of Hope, Monrovia, CA
2Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA
3Systems Biology Department, Beckman Research Institute - City of Hope, Monrovia, CA
4Department of Hematology, Shengjing Hospital of China Medical University, Shenyang, Heilongjiang, China
5Department of Systems Biology, Beckman Research Institute, City of Hope National Medical Center, Monrovia, CA
6Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA
7Systems Biology Department, City of Hope, Monrovia, CA
8Harvard Medical School, Boston, MA
9Department of Cancer Genetics and Epigenetics, Beckman Research Institute - City Of Hope, Duarte, CA
10Department of Oncology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA, New York, NY
11Department of Medical Oncology, Dana-farber/Boston Children's Cancer and Blood Disorders Ctr, Boston, MA
12Broad Institute of MIT and Harvard, Cambridge, MA
13Department of Medicine, Brigham and Women’s Hospital, Boston, MA
14Dana-Farber Cancer Institute and Harvard Medical School, Boston
15Department of Molecular and Cellular Biology, Beckman Research Institute, Monrovia, CA

Jaco A. C. Van Bruggen1,2*, Fleur Peters1,2*, Gaspard Cretenet1,2*, J. Joseph Melenhorst, PhD3,4, Eric Eldering, PhD1,2* and Arnon P. Kater, MD, PhD1,2

1Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
2Department of Hematology, Cancer Center Amsterdam, Lymphoma and Myeloma Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
3Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia
4Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA

Audrey L Smith, BS1, Alexandria P Eiken, BS1, Sydney A Skupa, BS1*, Dalia Y Moore, MS1*, Avyakta Kallam, MD2, Christopher D'Angelo, MD2*, Gregory R Bociek, MD3, Matthew A. Lunning, DO, FACP2, Julie M. Vose, MD, MBA2, Ben Powell, PhD4*, Gideon Bollag, PhD4 and Dalia ElGamal, MSc, PhD1

1Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE
2Division of Hematology & Oncology, Department of Internal Medicine, University of Nebraska Medical Center- Fred and Pamela Buffett Cancer Center, Omaha, NE
3Division of Hematology & Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
4Plexxikon Inc., Berkeley, CA

Alicia Vaca, PhD1*, Nikolaos Ioannou, PhD, MSc, BSc2*, Mariela Sivina, PhD3*, Elisavet Vlachonikola, PhD4*, Karen Clise-Dwyer, PhD5*, Ekaterina Kim, Ph.D1*, Dan Li, PhD5*, Qing Ma, PhD6*, Alessandra Ferrajoli, MD7, Zeev E. Estrov, MD1, William G. Wierda8, Piers E.M. Patten, FRCP, FRCPath, PhD9, Alan G. Ramsay, BSc, MSc, PhD10 and Jan A. Burger, MD, PhD1

1Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
2Faculty of Life Sciences & Medicine, King’s College London, London, United Kingdom
3Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX
4Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
5Department of Hematopoietic Biology & Malignancy, The University of Texas M.D. Anderson Cancer Center, Houston, TX
6Department of Hematopoietic Biology & Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
8Department of Leukemia, University of Texas M.D. Anderson Cancer Center, Houston, TX
9Comprehensive Cancer Centre, King’s College London, London, United Kingdom
10Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom

Zhenghao Chen, MSc1,2*, Helga Simon-Molas1,3*, Gaspard Cretenet1*, Beatriz Valle-Argos4*, Francesco Forconi5*, Bauke V Schomakers6*, Michel van Weeghel6*, Dean Bryant7*, Jaco A. C. Van Bruggen1,2*, Fleur Peters1*, Gerritje J. W. van der Windt8*, Arnon P. Kater, MD, PhD2,9, Graham Packham4* and Eric Eldering1,2*

1Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
2Amsterdam Institute of Infection and Immunity, Cancer Center Amsterdam, and Lymphoma and Myeloma Center (LYMMCARE), Amsterdam, Netherlands
3Department of Hematology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
4Cancer Research UK Centre, Cancer Sciences, University of Southampton, Southampton, United Kingdom
5Department of Haematology, Southampton University Hospital Trust, Southampton, United Kingdom
6Laboratory Genetic Metabolic Diseases, Amsterdam UMC-AMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam, Netherlands
7Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
8Genmab, Utrecht, Netherlands
9Department of Hematology, Amsterdam UMC, Amsterdam, Netherlands

Francesca Arruga, PhD1*, Andrea Iannello, PhD2*, Nikolaos Ioannou, PhD, MSc, BSc3*, Alberto Maria Todesco4*, Marta Coscia, MD, PhD5*, Riccardo Moia, MD6*, Gianluca Gaidano, MD7, John N. Allan, MD, PhD8, Richard Furman9, Tiziana Vaisitti, PhD10, Alan G. Ramsay, BSc, MSc, PhD11 and Silvia Deaglio, MD12

1Department of Medical Sciences, University of Torino, Turin, Italy
2Medical Sciences, University of Turin, Turin, Italy
3King's College London, London, ENG, United Kingdom
4Department of Medical Sciences, University of Turin, Torino, Italy
5Department of Molecular Biotechnology and Health Sciences and Division of Hematology, University of Torino, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy
6Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
7Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
8Weill Cornell Medicine, New York, NY
9Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY
10Department of Medical Sciences, University of Torino, Torino, To, Italy
11Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom
12Department of Medical Sciences, University of Turin, School of Medicine, Torino, To, Italy

Vi Lam1*, Xiaoguang Wang2*, Scott R Best, BS3*, Nur Bruss, BS3*, Tingting Liu2*, Olga Danilova2*, Tanya Siddiqi, MD4, Nathan Pennock3* and Alexey V. Danilov, MD, PhD5

1City Of Hope, Duarte, CA
2City of Hope, Duarte, CA
3Oregon Health and Science University, Portland, OR
4Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
5City of Hope Comprehensive Cancer Center, Duarte, CA

*signifies non-member of ASH