-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Monday, December 13, 2021: 6:00 PM-8:00 PM
Hall B5, Level 1, Building B (Georgia World Congress Center)

Michael H Kramer, MD, PhD1, Qiang Zhang, PhD2*, Robert W. Sprung2*, Petra Erdmann-Gilmore2*, Daniel R George1*, Nichole M Helton1*, Sharon E Heath1*, Jacqueline E. Payton, MD, PhD3, Peter Westervelt, MD, PhD1, Christopher A Miller, PhD1*, Matthew J. Walter, MD1, Daniel C. Link, MD1, John F. DiPersio, MD, PhD1, R Reid Townsend, MD, PhD2* and Timothy J Ley, MD1

1Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, MO
2Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, Saint Louis, MO
3Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO

Taehyung Kim, MSc1,2,3, Hyewon Lee, MD1,4, Jose-Mario Capo-Chichi, PhD5*, Myung Hee Chang, MD1,6*, Young Seok Yoo, BSc1*, Gurbaksh Basi7*, Troy Ketela, PhD7*, Adam C. Smith, PhD8,9*, Anne Tierens, MD, PhD8,9, Mark D. Minden, MD, PhD1, Zhaolei Zhang, PhD2,3,10* and Dennis Dong Hwan Kim, MD, PhD1,11*

1Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
2Department of Computer Science, University of Toronto, Toronto, ON, Canada
3The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
4Center for Hematologic Malignancy, National Cancer Center, Goyang, Korea, Republic of (South)
5Department of Clinical Laboratory Genetics, Genome Diagnostics Laboratory Medicine Program, University of Toronto, Toronto, ON, Canada
6National Health Insurance Service Ilsan Hospital, Ilsan, Korea, Republic of (South)
7Princess Margaret Genomics Centre, University Health Network, Toronto, ON, Canada
8Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
9Laboratory Medicine Program, University Health Network, Toronto, ON, Canada
10Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
11Hans Messner Allogeneic Blood and Marrow Transplant Unit, Princess Margaret Cancer Centre, Toronto, Canada

Richard J Marrero, PharmD1, Abdelrahman H Elsayed, MSc2, Xueyuan Cao3*, Huiyun Wu, PhD4*, Lei Wang, MS4*, Raul C Ribeiro, MD3, Jeffrey E. Rubnitz, MD5, Stanley B Pounds, PhD4* and Jatinder K. Lamba, PhD6

1Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, GAINESVILLE, FL
2Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL
3St. Jude Children's Research Hospital, Memphis, TN
4Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN
5Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN
6Department of Pharmacotherapy and Translational Research, University of Florida, College of Pharmacy, Pharmacotherapy and Translational Re, Gainesville, FL

Brian Ball, MD1, Shukaib Arslan, MD2, Paul Koller, MD2, Joyce Murata-Collins, PhD3, Michelle Afkhami, MD4*, Raju Pillai, MD4*, Karl Gaal, MD1*, Amandeep Salhotra, MD2, Monzr M. Al Malki, MD2, Ahmed Aribi, MD2, Haris Ali, MD2, Salman Otoukesh, MD2*, Idoroenyi Amanam, MD2, Ryotaro Nakamura, MD2, Eileen P. Smith, MD2, Forrest Stewart, MD1*, Guido Marcucci, MD5, Vinod A. Pullarkat, MD6 and Ibrahim Aldoss, MD2

1City of Hope National Medical Center, Duarte, CA
2Department of Hematology/HCT, City of Hope National Medical Center, Duarte, CA
3City of Hope Medical Center, Duarte, CA
4Department of Pathology, City of Hope National Medical Center, Duarte, CA
5Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
6Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA

Amer M. Zeidan, MD1, Maya Ridinger, PhD2*, Peter J.P. Croucher, PhD2*, Errin Samuëlsz2*, Mark Erlander, PhD2*, Katherine L. Ruffner, MD2 and Eunice S. Wang, MD3

1Department of Internal Medicine, Section of Hematology, Yale University School of Medicine, East Haven, CT
2Cardiff Oncology, San Diego, CA
3Roswell Park Comprehensive Cancer Center, BUFFALO, NY

Yazan Numan, MD1,2, Hamza Tariq, MD3, Jie Fan1*, Ping Xie1*, Madelyn Burkart, MD1, Yasmin Abaza, MD1, Yi-Hua Chen, MD3*, Shira Dinner, MD1, Olga Frankfurt, MD1*, Jayesh Mehta, MD4*, Hui Zhang, PhD5*, Jessica K. Altman, MD1,2 and Bin Zhang, MD/Ph.D1*

1Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL
2Robert H. Lurie Comprehensive Cancer Center, Chicago, IL
3Division of Hematopathology, Northwestern University Feinberg School of medicine, Chicago, IL
4Stem Cell Transplantation and Cell Therapy Program, Northwestern University Fienberg School of Medicine, Chicago, IL
5Biostatistics, Preventive Medicine; Feinberg School of Medicine; Northwestern University, Chicago, IL

Chad A Hudson, MD, PhD, Laura Pardo*, Loren L. Lott*, Michael R. Loken, PhD* and Lisa Eidenschink Brodersen, PhD

Hematologics, Inc., Seattle, WA

Yahan Li1,2*, Xue Sun1,3*, Xin Wang, MD, PhD1,3,4 and Xiaosheng Fang, MD, PhD3,5*

1Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
2Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, AL, China
3Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
4School of Medicine, Shandong University, Jinan, China
5Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China

Irene Graf, MD1*, Georg Greiner, MD2*, Rodrig Marculescu, MD3*, Karoline V. Gleixner, MD1,4*, Susanne Herndlhofer1*, Gabriele Stefanzl1*, Paul Knoebl, MD1*, Ulrich Jaeger1, Alexander Hauswirth, MD1*, Ilse Schwarzinger, MD3*, Renate Thalhammer, MD3*, Michael Kundi5*, Gregor Hoermann, MD4,6, Gerlinde Mitterbauer-Hohendanner, MD3*, Peter Valent, MD1,4 and Wolfgang R. Sperr, MD1,4*

1Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
2Medical Diagnostic Laboratories, Ihr Labor, Vienna, Austria
3Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
4Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria
5Institute of Environmental Health, Medical University of Vienna, Vienna, Austria
6MLL Munich Leukemia Laboratory, Munich, Germany

Alessandro Paoli1*, Daniela Bellarosa, PhD1*, Alessandro Bressan1*, Francesco Bertolini, MD, PhD2, Scott R. Solomon, MD3, Pau Montesinos, PhD, MD4*, Sudipto Mukherjee, MD, PhD, MPH5, Stephen A Strickland6, Giovanni Marconi, MD7*, Armando Santoro8*, Roland B. Walter, MD9, Rachel J. Cook, MD10, Maria Calbacho, MD11*, Susana Vives12*, Salman Fazal, MD13*, Farhad Ravandi, MB Bs14, Krzysztof Brzozka, PhD15*, Tomasz Rzymski, PhD15*, Milena Mazan15*, Simone Baldini, MD1*, Niccolò Ravenni1*, Monica Binaschi, PhD1*, Dirk Laurent, MD1* and Andrea Pellacani, PhD, MD1*

1Menarini Group, Florence, Italy
2European Institute of Oncology, Milano, ITA
3Leukemia Program, Northside Hospital Cancer Center Institute, Atlanta, GA
4Hospital Universitari i Politècnic La Fe, Valencia, Spain
5Cleveland Clinic, Cleveland, OH
6Vanderbilt-Ingram Cancer Center, Nashville, TN
7Hematology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
8Humanitas Clinical and Research Center IRCCS, Humanitas University, Milano, Italy
9Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
10Knight Cancer Institute, Oregon Health and Science University, Portland, OR
11Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain, Spain
12ICO-Hospital Germans Trias i Pujol, Badalona, ESP
13Allegheny Health Network Cancer Institute, Pittsburgh, PA
14MD Anderson Cancer Center, Houston, TX
15Ryvu Therapeutics, Cracow, Poland

James M. Foran, MD1,2, Michael G. Heckman, MS3*, Yesesri Cherukuri4*, Mikolaj Wieczorek3*, Zaid Abdel Rahman, MD5,6, Liuyan Jiang, MD7, Hemant S. Murthy, MD8, Laura Finn, MD9, Talha Badar, MD10, Lisa Z. Sproat, MD11, Yanyan Lou, MD12*, James R. Cerhan, MD, PhD13 and Yan Asmann, PhD14

1Division of Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic Florida, Jacksonville, FL
2Mayo Clinical Cancer Center, Jacksonville, FL
3Biostatistics & Health Sciences Research, Mayo Clinic, Jacksonville, FL
4Mayo Clinic, Jacksonville, FL
5Stem Cell Transplantation and Cellular therapies, University of Texas MD Anderson Cancer Center, Houston, TX
6Stem Cell Transplantation and Cellular Therapies, University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL
8Division of Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL
9Ochsner Medical Center, New Orleans, LA
10Division of Hematology and Oncology, Mayo Clinic, Florida
11Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ
12Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL
13Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
14Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL

Tommaso Matteuzzi, PhD1*, Daniele Dall'Olio, PhD1*, Eric Sträng, PhD2*, Alessandra Merlotti, PhD1*, Javier Martinez Elicegui, PhD3*, Axel Benner, PhD4*, Maral Saadati, PhD5*, Julia Krzykalla, PhD4*, Caroline A. Heckman, PhD6, Ana Heredia Casanoves7*, Jurjen Versluis8*, María Abáigar3*, Alberto Hernandez-Sanchez3*, Laura Jamilis7*, Peter JM Valk, PhD9, Klaus H. Metzeler, MD10, Rosa Ayala11*, Joaquin Martinez Lopez12*, Herve Dombret, MD, PhD13, Pau Montesinos, PhD, MD14*, Jorge Sierra, MD, PhD15, Claude Preudomme16*, Frederick Damm2*, Ken I Mills17, Raúl Azibeiro Melchor3*, Jiří Mayer, Prof, MD18, Christian Thiede, MD19, Maria Teresa Teresa Voso, MD20, Sergio Amadori, MD20, Guillermo Sanz, MD, PhD21, Frederico Calado22*, Konstanze Döhner, MD23, Verena I Gaidzik, MD24, Michael Heuser, Prof., MD25*, Torsten Haferlach, MD26, Marta Sobas27*, Amin T. Turki, MD28, Dirk Reinhardt, MD28, Rubén Villoria Medina7*, Michel van Speybroeck, MSc29*, Renate Schulze-Rath30*, Jesús M Hernández Rivas, MD, PhD3, Brian J.P Huntly, MB ChB, FRCPath, FMedSci, PhD31*, Hartmut Döhner, MD32, Gert J. Ossenkoppele, M.D., Ph.D.33, Castellani Gastone, PhD34* and Lars Bullinger2

1Physics and Astronomy Department, University of Bologna, Bologna, Italy
2Charité Universitätsmedizin Berlin, Berlin, Germany
3Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
4Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
5Saadati Solutions, Ladenburg, Germany
6Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
7GMV Innovating Solutions, Valencia, Spain
8Erasmus University Medical Center Cancer Institute, Rotterdam, Rotterdam, Netherlands
9Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
10Department of Hematology, Cell Therapy and Hemostaseology, University of Munich, Leipzig, Germany
11Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
12Hematology Department Hospital 12 de Octubre, Hematological Malignancies Clinical Research Unit H12O-CNIO, Madrid, Spain
13Hematology, Hôpital Saint-Louis, Paris, France
14Hospital Universitario y Politécnico La Fe, Valencia, Spain
15Hematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
16University Hospital, Lille, France
17Patrick G Johnston Centre for Cancer Research, Queens University Belfast, Belfast, United Kingdom
18University Hospital Brno, Brno, Czech Republic
19Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany
20University of Roma Tor Vergata, Rome, Italy
21Hematology Deparment, Hospital Universitario La Fe, Valencia, Spain
22Novartis, Oncology Region Europe, Basel, Switzerland
23Ulm University Hospital, Ulm, Germany
24Internal Medicine III, Internal Medicine III, Ulm, Germany
25Department for Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
26MLL Munich Leukemia Laboratory, Munich, Germany
27Department of Hematology, Wroclaw Medical University, Wroclaw, Poland
28Essen University Hospital, Essen, Germany
29Data Sciences, Janssen Pharmaceutica N.V., Beerse, Belgium
30Bayer Pharma AG, Berlin, Berlin, Germany
31Wellcome - MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom
32Internal Medicine III, University of Ulm, Ulm, Germany
33Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, Netherlands
34Department of Experimental, Diagnostic and Specialty Medicine - DIMES, University of Bologna, Bologna, Italy

Maria Rodriguez Zabala, MSc1*, Ramprasad Ramakrishnan, PhD1*, Katrin Reinbach, BSc1*, Leal Oburoglu, PhD2*, Somadri Ghosh, PhD1*, Ton Falqués, PhD1*, Pablo Peña-Martínez, PhD1*, Noelia Puente-Moncada, PhD1*, Thoas Fioretos, MD1*, Anna Hagstroem-Andersson, PhD1, Niels-Bjarne Woods, PhD2* and Marcus Järås, PhD1

1Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden
2Division of Molecular Medicine and Gene Therapy, Lund University, Lund, Sweden

Francesca Tiso, MSc1*, Thessa N. Koorenhof-Scheele1*, Erik Huys1*, Joost H.A. Martens2*, Aniek O. De Graaf, PhD1*, Bert A. van der Reijden, PhD3, Saskia M. C. Langemeijer, MD, PhD4*, Frank W. M. B. Preijers1*, Leonie I. Kroeze5* and Joop H. Jansen, PhD1

1Department of laboratory medicine – laboratory of hematology, Radboudumc, Nijmegen, Netherlands
2Department of Molecular Biology, Radboud Institute of Molecular Life Sciences, Nijmegen, Netherlands
3Department of laboratory medicine – laboratory of hematology, Radboudumc, Nijmegen, GL, Netherlands
4Department of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
5Department of Pathology, Radboudumc, Nijmegen, Netherlands

Jamie A Moore, BSc, MSc1*, Jayna J Mistry, BSc1*, Charlotte Hellmich2*, Rebecca H Horton3*, Edyta Wojtowicz, PhD4*, Aisha Jibril, BSc5*, Tom Wileman, PhD6*, Matthew Jefferson2*, Naiara Beraza, PhD7*, Kristian M Bowles, MBBS, PhD8,9 and Stuart A Rushworth, PhD1

1Norwich Medical School, University of East Anglia, Norwich, United Kingdom
2The University of East Anglia, Norwich, GBR
3Norwich Medical School, The University of East Anglia, Norwich, United Kingdom
4Norwich Research Park, Earlham Institute, Norwich, ENG, United Kingdom
5Norwich Medical School, University of East Anglia, Norwich, ENG, United Kingdom
6Quadram Institute, Norwich, United Kingdom
7Quadram Institute Bioscience, Norwich, United Kingdom
8Norwich Medical School, Norwich, United Kingdom
9Department of Haematology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, United Kingdom

Fabio Guolo, MD1,2*, Paola Minetto, MD1, Marino Clavio, MD1*, Maurizio Miglino, PhD1*, Riccardo Marcolin, MD1*, Monica Passannante, MD1*, Carola Riva, MD1*, Michela Frello, MD1*, Chiara Vernarecci, MD1*, Elisabetta Tedone3*, Nicoletta Colombo, PhD3*, Enrico Carminati1*, Girolamo Pugliese1*, Clara Nurra1*, Antonia Cagnetta, MD1*, Michele Cea1,2*, Marco Gobbi, MD1* and Roberto M. Lemoli, MD1,2

1Clinic of Hematology, Department of Internal Medicine (DiMI), IRCCS Ospedale Policlinico San Martino, Genova, Italy
2Clinic of Hematology, Department of Internal Medicine (DiMI), Policlinico San Martino, IRCCS per l’Oncologia, University of Genoa, Genoa, Italy
3Clinical Flow Cytometry Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy

Muharrem Muftuoglu, MD1, Li Li, M.D.2*, Mahesh Basyal, BSc1*, Shaoheng Liang3*, Carissa J. Ball4*, Ken Chen, PhD3*, Prasanna Kumar, PhD5*, Arnaud Lesegretain5*, Naval Daver, MD6 and Michael Andreeff, MD, PhD1

1Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX
4Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
5Daiichi Sankyo Inc., Basking Ridge, NJ
6MD Anderson Cancer Center, Houston, TX

Stefan G.C. Mestrum1,2*, Roanalis B.Y. Vanblarcum1*, Roosmarie J.M. Drent3*, Norbert C.J. De Wit4*, Bert T. Boonen5*, Wouter L.W. van Hemert5*, Anton H.N. Hopman6*, Frans C.S. Ramaekers6* and Mathie P.G. Leers3

1Department of Clinical Chemistry & Hematology, Zuyderland Medical Center, Sittard-Geleen, Netherlands
2Department of Molecular Cell Biology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, AL, Netherlands
3Zuyderland Medical Center, Sittard-Geleen, Netherlands
4Central Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, Netherlands
5Department of Orthopedic Surgery, Zuyderland Medical Center, Heerlen, Netherlands
6Department of Molecular Cell Biology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands

Eunice S. Wang, MD1, Jessica K. Altman, MD2, Mark D. Minden, MD, PhD3, Ruishan Wu, MS4*, Elizabeth Shima Rich, MD, PhD4 and Jason E. Hill, PhD4*

1Roswell Park Comprehensive Cancer Center, BUFFALO, NY
2Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
3Princess Margaret Hospital, Toronto, Canada
4Astellas Pharma, Inc., Northbrook, IL

Jennifer Lauren Kamens, MD1, Anitria Cotton, MBA2*, Jeannie W Lam, BS1*, Jinjun Dang, PhD1*, Aman Seth, MS3*, Baranda S Hansen4*, Shondra M. Pruett-Miller, PhD4*, Anang Shelat, PhD5* and Tanja Andrea Gruber, MD1

1Department of Pediatrics; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Palo Alto, CA
2Division of Experimental Hematology, St. Jude Children's Research Hospital, Memphis, TN
3Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN
4Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN
5Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN

Fieke W Hoff, MD1*, Yihua Qiu2*, Brandon Brown, MD3*, Robert B. Gerbing, MA4*, Alan S. Gamis, MD, MPH5, Richard Aplenc, MD, PhD6, Edward A. Kolb, MD7, Todd A. Alonzo, PhD8*, Soheil Meshinchi, M.D., Ph.D.9, Gaye Jenkins10*, Terzah M. Horton, MD, PhD11 and Steven Kornblau, MD12,13

1UT Southwestern Medical Center, Dallas, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Pediatrics, UT MD Anderson Cancer Center, Houston
4Children's Oncology Group, Monrovia, CA
5Children's Mercy Kansas City, Kansas City, MO
6Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
7Division of Oncology, Nemours Alfed I. duPont Hospital For Children, Wilmington, DE
8Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
9Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
10Baylor College of Medicine, Houston
11Baylor College of Medicine, Houston, TX
12Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
13Leukemia / Stem cell Transplantation & Cellular Therapy, UT MD Anderson Cancer Center, HOUSTON, TX

Antonella Padella, PhD1*, Stephan Hutter, PhD2*, Wencke Walter, PhD2*, Constance Baer, PhD2, Andrea Ghelli Luserna Di Rorà, PhD1*, Martina Ghetti, PhD1*, Lorenzo Ledda1*, Matteo Paganelli1*, Claudia Haferlach, MD2, Wolfgang Kern, MD2, Giorgia Simonetti, PhD1*, Giovanni Martinelli, MD3 and Torsten Haferlach, MD2

1Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
2MLL Munich Leukemia Laboratory, Munich, Germany
3Scientific Directorate, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy

Pia Michler1*, Franziska Auer2, Rabea Wagener3*, Triantafyllia Brozou3*, Ulrike Anne Friedrich1*, Carolin Walter4*, Martin Dugas4,5*, Arndt Borkhardt3, Friedrich Stölzel6* and Julia Hauer1,2*

1Pediatric Hematology and Oncology, Department of Pediatrics, University Hospital "Carl Gustav Carus", TU Dresden, Dresden, Germany
2National Center for Tumor Diseases (NCT), Dresden, Germany
3Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Duesseldorf, Medical Faculty, Duesseldorf, Germany
4Institute of Medical Informatics, University of Muenster, Muenster, Germany
5Institute of Medical Informatics, Heidelberg University Hospital, Heidelberg, Germany
6Department of Hematology and Oncology, University Hospital “Carl Gustav Carus”, TU Dresden, Dresden, Germany

Mihee Kim, MD1*, Taehyung Kim, MSc2,3, Seo-Yeon Ahn, MD1*, Sung-Hoon Jung, MD1*, Ga-Young Song1*, Deok-Hwan Yang, MD, PhD1*, Je-Jung Lee, MD, PhD1, Seunghyun Choi, PhD4*, MiYeon Kim4*, Jae-Sook Ahn, MD, PhD1,4*, Hyeoung-Joon Kim, MD, PhD1,4 and Dennis Dong Hwan Kim, MD, PhD5*

1Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Jeollanam-do, Korea, Republic of (South)
2The Donnelly Centre for Cellular and Biomolecular Research, Donnelly Centre For Cellular & Biomolecular Research, Toronto, ON, Canada
3The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
4Genomic Research Center for Hematopoietic Diseases, Chonnam National University Hwasun Hospital, Jeollanam-do, Korea, Republic of (South)
5Hans Messner Allogeneic Blood and Marrow Transplant Unit, Princess Margaret Cancer Centre, Toronto, Canada

Adam J. Lamble, MD1, Robert B. Gerbing, MA2*, Jenny L. Smith, MSc, MEd3*, Rhonda E. Ries, MA3*, Edward A. Kolb, MD4, Todd A. Alonzo, PhD2,5* and Soheil Meshinchi, M.D., Ph.D.3

1Division of Hematology and Oncology, Seattle Children's Hospital, Seattle, WA
2Children's Oncology Group, Monrovia, CA
3Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
4Division of Oncology, Nemours Alfed I. duPont Hospital For Children, Wilmington, DE
5Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA

Sonali P. Barwe, PhD, MSc1, Erin Lynn Crowgey, PhD1*, Qinzhuo Zhang1*, E. Anders Kolb, MD1 and Anilkumar Gopalakrishnapillai, PhD, MSc2

1Nemours Center for Cancer and Blood Disorders, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE
2Nemours Center for Cancer and Blood Disorders, Nemours, Wilmington, DE

Agnieszka Wierzbowska, MD, PhD1, Agnieszka Pluta, MD, PhD2*, Anna Czyz, MD PhD3*, Marta Antonina Libura, MD PhD4*, Sebastian Giebel, MD, PhD5*, Magdalena Czemerska, MD PhD2*, Piotr Stelmach, MD PhD2*, Michal Soin, M.Sc.2*, Anna Kopinska, MD6*, Krzysztof Wozniczka, MD PhD6*, Grzegorz Helbig, MD PhD6*, Marta Sobas3*, Tomasz Wróbel, MD, PhD3, Andrzej Szczepaniak, MD PhD7*, Lidia Gil, MD, PhD7, Karol Wojcik, MD8*, Malgorzata Razny, MD PhD8*, Magdalena Dutka, MD, PhD9*, Maria Bieniaszewska, MD, PhD10*, Janusz Halka, MD PhD11*, Tomasz Gromek, MD PhD12*, Marek Hus, MD PhD12*, Elzbieta Patkowska, MD, PhD13*, Jolanta Wozniak, PhD14*, Edyta Cichocka, MD PhD15*, Agata Obara, MD16*, Agnieszka Kopacz, MD, PhD17*, Katarzyna Dulik, MD5*, Jerzy Holowiecki, MD PhD5*, Damian Mikulski18*, Ewelina Perdas, Ph.D.19*, Wojciech Fendler, M.D., Ph.D.19*, Nicole M. Cruz, MD20, Nuria Mencia-Trinchant, PhD20*, Pinkal Desai, MD, MPH21, Sangmin Lee, MD21, Michael B. Samuel, MD22*, Justin D. Kaner, MD23, Ellen Ritchie, MD 24, Monica L. Guzman, PhD21 and Gail J. Roboz, MD25

1Department of Hematology, Copernicus Memorial Hospital, Łódź, Poland
2Department of Hematology, Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
3Department of Hematology, Wroclaw Medical University, Wroclaw, Poland
4Department of Hematology, Oncology and Internal Medicine, Warsaw Medical University, Warsaw, Poland
5Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
6Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland
7Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
8Department of Hematology, Rydygier Specialist Hospital, Krakow, Poland
9Department of Hematology, Medical University of Gdansk, Gdansk, Poland
10Department of Hematology, Medical University of Gdansk, Gdańsk, Poland
11Department of Hematology, Warmian-Masurian Cancer Center of The Ministry of the Interior and Administration’s Hospital, Olsztyn, Poland
12Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland
13Hematology Department, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
14Division of Hematological Diagnostics, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
15Department of Hematology and Bone Marrow Transplantation, Copernicus Memorial Hospital, Torun, Poland
16Department of Hematology, Holly Cross Oncology Center, Kielce, Poland
17Department of Hematology, Medical University of Rzeszow, Rzeszow, Poland
18Department of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland
19Department of Biostatistics and Translational Medicine, Medical University of Lodz, Łódź, Poland
20Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
21Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY
22Division of Hematology and Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
23Department of Internal Medicine, Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY
24Division of Hematology and Oncology, Weill Cornell Medical College New York Presbyterian, New York, NY
25Division of Hematology Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY

Katherine Tarlock, MD1,2, Leila Robinson2*, Todd A. Alonzo, PhD3,4*, Robert B. Gerbing, MA3*, Yi-Cheng Wang, MS3*, Rhonda E. Ries, MA2*, Amanda R. Leonti, MS2*, Jenny L. Smith, MSc, MEd2*, Tiffany A. Hylkema, BS2*, Quy Le, PhD2*, Xiaotu Ma, PhD5*, E. Anders Kolb, MD6, Richard Aplenc, MD, PhD7, Jessica A. Pollard, MD8,9 and Soheil Meshinchi, M.D., Ph.D.2,10

1Division of Hematology and Oncology, Seattle Children's Hospital, Seattle, WA
2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
3Children's Oncology Group, Monrovia, CA
4Department of Preventive Medicine, University of Southern California, Monrovia, CA
5Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN
6Nemours Center for Cancer and Blood Disorders, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE
7Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
8Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA
9Harvard Medical School, Boston, MA
10Department of Pediatrics, University of Washington, Seattle, WA

Hope L Mumme, BSc1*, Swati S Bhasin, PhD2, Beena E Thomas, Ph.D1*, Deborah DeRyckere, BS, PhD1,2, Sharon M. Castellino, MD, MSc2,3, Douglas K Graham, MD, PhD2,3, Sunil S. Raikar, MD3,4 and Manoj Bhasin, PhD2

1Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA
2Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
3Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA
4Aflac Cancer and Blood Disorders Center, Emory University/Children's Healthcare of Atlanta, Atlanta, GA

Vivek M. Shastri, PhD1, Lata Chauhan, PhD1*, Todd A. Alonzo, PhD2*, Yi-Cheng Wang, MS3*, Richard Aplenc, MD, PhD4, Betsy A Hirsch, PhD5*, Alan S. Gamis, MD, MPH6, Soheil Meshinchi, M.D., Ph.D.7 and Jatinder K. Lamba, PhD8

1Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL
2Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
3Children's Oncology Group, Monrovia, CA
4Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
5Division of Molecular Pathology and Genomics, University of Minnesota, Minneapolis, MN
6Hematology/Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO
7Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
8Department of Pharmacotherapy and Translational Research, University of Florida, College of Pharmacy, Pharmacotherapy and Translational Re, Gainesville, FL

Anne-Sofie Skou, MD1*, Kristian Løvvik Juul-Dam, MD, PhD2*, Erik Delsing Malmberg, MD, PhD3*, Anna Rehammar4*, Anastasia Soboli5*, Azadeh Anbarlou, MA6*, Erik Kristiansson7*, Jonas Abrahamsson, MD, PhD8*, Bernward Zeller, MD, PhD9*, Kirsi Jahnukainen, MD, PhD10*, Edwin Sonneveld, MSc, PhD11*, Birgitte Lausen, MD, PhD12, Anni Aggerholm, MSc, PhD13*, Hans Beier Ommen, MD, PhD13*, Henrik Hasle, MD, PhD2 and Linda Fogelstrand, MD, PhD5

1Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus N, Denmark
2Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
3Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden
4School of Public Health and Community Medicine/Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
5Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
6Department of Laboratory Medicine, University of Gothenburg, Gothenburg, Sweden
7Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden
8Department of Pediatrics, Queen Silvia Children's Hospital, Gothenburg, Sweden
9Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway
10Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
11Princess Máxima Center for Pediatric Oncology and Dutch Childhood Oncology Group, Utrecht, Netherlands
12Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark
13Department of Hematology, Aarhus University Hospital, Aarhus, Denmark

Tsz-Kwong Man, PhD*, Mohammad Javad Najaf Panah, MS*, Jessica L. Elswood, PhD*, Pavel Sumazin, PhD* and Michele S. Redell, MD PhD

Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX

Tong-Yoon Kim, MD1*, Byung Sik Cho, M.D., Ph.D.2*, Gi June Min, M.D., Ph.D.2, Sung-Soo Park, M.D., Ph.D.2*, Silvia Park, M.D., Ph.D.3*, Jae-Ho Yoon, MD2, Sung-Eun Lee, M.D., Ph.D.4*, Ki-Seong Eom, M.D., Ph.D.2*, Yoo-Jin Kim, M.D., Ph.D.2, Seok Lee, M.D., Ph.D.2, Chang-Ki Min, M.D., Ph.D.2*, Seok-Goo Cho, M.D., Ph.D.5*, Dong-Wook Kim, M.D., Ph.D.5, Jong-Wook Lee, MD5 and Hee-Je Kim, M.D., Ph.D.2

1Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
2Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
3Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Gangnam-Gu, Korea, Republic of (South)
4Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, TX, Korea, Republic of (South)
5Department of Hematology, The Catholic University of Korea, Seoul, Korea, Republic of (South)

Sarah Grasedieck1*, Ariene Cabantog2*, Liam MacPhee2, Junbum Im3, Christoph Rueß, MSc4*, Burcu Demir5*, Nadine Sperb, PhD4*, Frank G. Rücker, MD6*, Konstanze Döhner, MD7, Tobias Herold, MD8, Jonathan R. Pollack, MD, PhD9*, Lars Bullinger10, Arefeh Rouhi, PhD11* and Florian Kuchenbauer, MD, PhD, FRCPC11

1Michael Smith Laboratories, Dept of Microbiology and Immunology, 2125 East Mall, University of British Columbia, Vancouver, Canada
2BC Cancer Agency, Terry Fox Laboratory, Vancouver, BC, Canada
3BC Cancer Agency, Terry Fox Laboratory, Vancouver, BC, CAN
4Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany
5Dept of Internal Medicine III, Ulm University Hospital, Ulm, Germany
6Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
7University Hospital of Ulm, Ulm, Germany
8Laboratory for Leukemia Diagnostics, Department of Internal Medicine III, LMU, Munich, Germany
9Stanford Univ., Stanford, CA
10Department of Hematology, Oncology and Tumor Immunology, Campus Virchow, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
11Terry Fox Laboratory BC Cancer Agency, Vancouver, BC, Canada

Stuart Scott, BSc1,2*, Richard Dillon, MD PhD3,4, Christian Thiede, MD5,6, Sadia Sadiq, BSc7*, Ashley Cartwright, PhD8*, Clouston Hazel, PhD9*, Debbie Travis, PhD9*, Andrew D Chantry, PhD, MD10,11* and Liam Whitby, BSc9*

1Department of Oncology and Metabolism, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom
2UK NEQAS for Leucocyte Immunophenotyping, University of Sheffield, Sheffield, ENG, United Kingdom
3Department of Medical and Molecular Genetics, King's College, London, United Kingdom
4Department of Haematology, Guy's International Centre of Excellence in Myeloid Disorders, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
5Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, Dresden, Germany
6AgenDix, Angewandte molekulare Diagnostik mbH, Dresden, Germany
7UK NEQAS for Leucocyte Immunophenotyping, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom
8UK NEQAS for Leucocyte Immunophenotyping, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffied, United Kingdom
9UK NEQAS for Leucocyte Immunophenotyping, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom
10Department of Haematology, Sheffield Teaching Hospitals, Sheffield, United Kingdom
11Department of Oncology and Metabolism, Medical School, University of Sheffield, Sheffield, United Kingdom

Luis Miguel Veiga Veiga Nobre, PhD1*, Salvatore Federico Pedicona, PhD2*, Arran Dokal, MSc, PhD3,4*, Andrea Arruda, MSc5*, Ryan Smith, PhD3,4*, Calum Greenhalgh, PhD6*, Francesca Patella7*, Pedro Casado-Izquierdo8*, Bela Wrench, MBBS, MD3*, Jane Theaker1*, Andrew Thompson1*, Mark D. Minden, MD, PhD9, John G. Gribben, MD, DSc, FRCP, FMedSci, FRCPath8, David James Britton, BSc, PhD3,4* and Pedro Cutillas, PhD10*

1Kinomica Ltd, Macclesfield, United Kingdom
2Barts Cancer Institute, QMUL, London, United Kingdom
3Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
4Kinomica Ltd., Macclesfield, United Kingdom
5Leukemia Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
6Kino, Macclesfield, United Kingdom
7Kinomica, Macclesfield, GBR
8Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
9Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
10Centre for Genomics and Computational Biology, Queen Mary University of London, London, United Kingdom

Maher Albitar, MD1*, Andrew Ip, MD, MSc2, Andre H. Goy, MD3*, Jeffrey Justin Estella, BS, MS1*, Ivan De Dios, BS1*, Wanlong Ma1*, Andrew L. Pecora, MD4*, Jamie Koprivnikar, MD5* and James K McCloskey, MD5

1Genomic Testing Cooperative, Irvine, CA
2Division of Lymphoma, Division of Outcomes and Value Research, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ
3Division of Lymphoma, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ
4John Theurer Cancer Center, Hackensack Meridian Health, Division of Multiple Myeloma, Hackensack, NJ
5Division of Leukemia, John Thuerer Cancer Center at Hackensack University Medical Center, Hackensack, NJ

Markus D Lacher, PhD1*, Michelle A Richardson, MS1*, Steven A Schaffert, PhD1*, Ryosuke Kita, MD, PhD1*, Marianne T Santaguida, PhD, BSc1*, Erica K Anderson, MS1*, Jordan Roselli, MS1*, Wade Anderson, PhD1*, Arisa Paul, MS1*, Christine Gu, MS1*, Kathryn Vanderlaag, PhD1*, Zhihong Zeng, MD2*, Abhishek Maiti, MBBS2, Courtney D. DiNardo, MD, MSCE2 and Marina Konopleva, MD, PhD2

1Notable Labs, Foster City, CA
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Pierre Peterlin1*, Camille Debord, PharmD2*, Alice Garnier, MD3*, Amandine Le Bourgeois, MD3*, Thierry Guillaume, MD, PhD4*, Marion Eveillard2*, Yannick Le Bris, PharmD, PhD5*, Béatrice Mahé, MD6*, Viviane Dubruille, MD3*, Nicolas Blin, MD3*, Anne Lok, MD3*, Cyrille Touzeau, MD, PhD7*, Thomas Gastinne, MD8*, Benoit Tessoulin, MD, PhD9*, Soraya Wuillème, PharmD, PhD10*, Catherine Godon11*, Olivier Theisen, MD2*, Maxime Jullien, MD3*, Sophie Vantyghem, MD3*, Philippe Moreau, MD, PhD12*, Steven Le Gouill13, Marie C Bene, PharmSci, PhD14* and Patrice Chevallier, MD15

1Clinical Hematology, HOPITAL HOTEL DIEU ET HME, NANTES CEDEX 1, France
2Hematology Biology, Nantes University Hospital, Nantes, France
3Clinical Hematology, Nantes University Hospital, Nantes, France
4CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France
5Department of Biological Hematology, Nantes University Hospital? hEMATOLOGY bIOLOGY, Nantes, France
6Centre Hospitalier Universitaire de Nantes, Nantes, France
7Hématologie, CHU de Nantes, Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Nantes, France
8Clinical Hematology, University Hospital of Nantes,, Nantes Cedex 1, France
9Université de Nantes, CNRS, INSERM, CRCINA, Nantes, France, Nantes, France
10Hematology Biology, University Hospital Hôtel Dieu, Nantes, France
11Hematology Biology, Nantes University Hospital, NANTES, FRA
12University Hospital Hôtel-Dieu, Nantes, Nantes, France
13Service d’hématologie clinique du CHU de Nantes, INSERM CRCINA Nantes-Angers, NeXT Université de Nantes, Nantes, France
14Nantes University Hospital, Hematology Biology, Nantes, France
15Department of Clinical Hematology, Nantes University Hospital, Nantes, France

Steven M. Johnson1*, Lori Ramkissoon, PhD1*, James Haberberger2*, Naomi L Ferguson, MD2*, Jonathan Galeotti, MD1*, Daniel R. Richardson, MD, MA, MSc3,4, Matthew C. Foster, MD4,5*, Jeffrey Ross, MD6*, Shakti H. Ramkissoon, MD, PhD2,7*, Joshua F. Zeidner, MD5,8, Daniel Duncan, MD2* and Nathan Montgomery, MD, PhD1,4

1Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
2Foundation Medicine, Inc., Morrisville, NC
3Division of Hematology/Oncology, Department of Medicine, The Ohio State University Wexner Medical Center, Chapel Hill, NC
4Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
5Division of Hematology/Oncology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
6Foundation Medicine Inc, Cambridge, MA
7Wake Forest School Of Medicine, Winston-Salem, NC
8Lineberger Comprehensive Cancer Center, UNC - Lineberger Comprehensive Cancer Center, Chapel Hill, NC

Douglas RA Silveira, MD1*, Prodromos Chatzikyriakou, PhD2*, Olena Yavorska3*, Sarah Mackie2*, Roan Hulks2*, Paulina Siejka-Zielinska4*, Anna Corby, B.Sc.5*, Alastair Smith6*, Benjamin Brown, B.Sc., PhD5*, Marlen Metzner, MSc7*, Thomas A. Milne8, Virginie Penard-Lacronique, PhD9,10*, Chunxiao Song4*, Maroof Hasan, MD11*, Anjan Thakurta, PhD12*, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath13,14, Skirmantas Kriaucionis, PhD15* and Lynn Quek, MBBCh, DPhil, MRCP (UK), FRCPath2,16*

1School of Cancer and Pharmaceutical Sciences, King's College London, London, ENG, United Kingdom
2School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom
3Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
4University of Oxford, Oxford, United Kingdom
5MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
6MRC Weatherall Institute of Molecular Medicine, NIHR Oxford Biomedical Research Centre Haematology Theme, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
7Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
8MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, NIHR Oxford Biomedical Research Centre Haematology Theme, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
9Gustave Roussy, INSERM U1170, Université Paris-Saclay, Villejuif, France
10INSERM U1170, Universit, Villejuif, France
11Bristol Myers Squibb, Princeton, NJ
12Translational Development and Diagnostics, Bristol Myers Squibb, Summit, NJ
13Department of Clinical Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
14Weatherall Institute of Molecular Medicine, Weatherall Inst. of Molecular Medicine, Oxford, United Kingdom
15Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom
16Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, United Kingdom

Ruoyang Shao* and Qifa Liu

Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Simon Renders, MD1,2,3*, Aino-Maija Leppä, MSc4,5*, Alexander Waclawiczek, PhD5,6*, Maike Janssen, MD7*, Elisa Donato, PhD5,8*, Cecilia Reyneri5,8*, Julia M. Unglaub, MD7*, Michael Hundemer, MD9*, Richard F. Schlenk, MD9,10,11, Simon Raffel, MD12,13, Carsten Müller-Tidow, MD14*, Tim Sauer, MD9* and Andreas Trumpp, PhD2,15

1Heidelberg University Hospital, Department of Internal Medicine V, Heidelberg, Germany
2Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany
3Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmBH), Heidelberg, Germany
4German Cancer Research Center (DKFZ), Division of Stem Cells and Cancer, Heideberg, DEU
5Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmBH), Heideberg, Germany
6DKFZGerman Cancer Research Center (DKFZ), Division of Stem Cells and Cancer, Heideberg, Germany
7Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany
8German Cancer Research Center (DKFZ), Division of Stem Cells and Cancer, Heideberg, Germany
9Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
10German Cancer Research Center, NCT-clinical trials office, Heidelberg, Germany
11National Center of Tumor Diseases, NCT-Trial Center, German Cancer Research Center, Heidelberg, Germany
12German Cancer Reseach Center, Heidelberg, Germany
13Heidelberg University Hospital, Department of Internal Medicine V, Heideberg, Germany
14Internal Medicine V - Hematology, Oncology & Rheumatology, University Hospital Heidelberg, Heidelberg, Germany
15Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany

Cheryl A C Peretz, MD1, Vanessa E Kennedy, MD2, Rhonda E. Ries, MA3*, Soheil Meshinchi, M.D., Ph.D.3 and Catherine C. Smith, MD4

1Pediatric Oncology, UCSF, San Francisco, CA
2University of California- San Francisco, San Francisco, CA
3Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
4Division of Hematology and Blood and Marrow Transplantation, University of California (San Francisco), San Francisco, CA

Dorian Forte1*, Roberto Maria Pellegrino2*, Francesco Fabbri, PhD3*, Ivan Vannini, PhD3*, Samantha Bruno, PhD1*, Giulia Corradi, PhD1*, Rafael J. Argüello, PhD4*, Gianluca Cristiano, MD5*, Sandra Buratta, PhD2*, Lorena Urbanelli, PhD2*, Carla Emiliani, PhD2,6*, Michele Cavo, MD, PhD1,7* and Antonio Curti, MD, PhD7

1Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “L. e A. Seràgnoli”, University of Bologna, Bologna, Italy
2Department of Chemistry, Biology and Biotechnology, Biochemistry and Molecular Biology Section, University of Perugia, Perugia, Italy
3Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
4Aix Marseille Univ, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France
5Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy
6Centro di Eccellenza sui Materiali Innovativi Nanostrutturati (CEMIN), University of Perugia, Perugia, Italy
7IRCCS Azienda ospedaliero-universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy

Isabel Weinhäuser, MSc1,2*, Diego A Pereira-Martins, MSc1*, Jacobien R Hilberink, BSc3*, Luciana Yamamoto Almeida, PhD4*, Douglas RA Silveira, MD5,6*, Lynn Quek, MBBCh, DPhil, MRCP (UK), FRCPath7,8*, Shanna M Hogeling, BSc MSc1*, Jose Mauricio Mota, MD PhD9*, Emanuele Ammatuna, MD. PhD10*, Antonio R. Lucena-Araujo, PhD11*, Gerwin A. Huls, MD PhD12, Jan Jacob Schuringa, PhD13,14* and Eduardo M Rego, MD, PhD15,16

1Department of Experimental Hematology, University Medical Center Groningen, Groningen, Netherlands
2Center Cell Based Therapy Institution, University of Sao Paulo, Ribeirao Preto, Brazil
3Department of Experimental Hematology, University Medical Center Groningen, Groningen, NLD
4Internal Medicine, University of São Paulo, Ribeirão Preto, Brazil
5Cancer & Pharmaceutical Sciences, King's College London, London, United Kingdom
6AC Camargo, Sao Paulo, BRA
7School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom
8Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, United Kingdom
9Campus Universitário, Monte Alegre, Ribeirão Preto, São Paulo, BRA
10Department of Hematology, University Medical Center Groningen, Groningen, NLD
11Department of Genetic, Federal University of Pernambuco, Recife - PE, AC, BRA
12Department of Hematology, University Medical Center Groningen, Groningen, GZ, Netherlands
13Department of Hematology, University Medical Center - Groningen, Groningen, Netherlands
14Department of Hematology, Cancer Research Center Groningen, University Medical Center Groningen, Groningen, Netherlands
15Medical Research Laboratory on Molecular Hematology (LIM-31), University of São Paulo, Sao Paulo, Brazil
16Center for Cell-based Therapy and Regional Hemotherapy Center, University of Sao Paulo at Ribeirao Preto Medical School, Ribeirao Preto, Sao Paulo, Brazil

Ja Min Byun, MD1, Changju Chun2*, Youngil Koh, MD, PhD3 and Tae-Young Yoon, PhD4*

1Seoul National University Hospital, Seoul, South Korea
2Seoul National University, Seoul, AL, Korea, Republic of (South)
3Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South)
4Seoul National University, Seoul, Korea, Republic of (South)

Antonio R. Lucena-Araujo, PhD1*, Diego A Pereira-Martins, MSc2,3*, Juan L Coelho-Silva, PhD4,5*, Isabel Weinhäuser, MSc2*, Pedro Luis Franca-Neto, PhD6*, Douglas RA Silveira, MD7,8*, Marinus M Lima, MD9*, Jan Jacob Schuringa, PhD10,11*, Luisa C Koury, MD4*, Raul Antônio Morais Melo, MD, PhD12*, Rosane Bittencourt, MD13*, Katia B Pagnano, MD, PhD14*, Elenaide C. Nunes, MD15*, Evandro Maranhão Fagundes, MD16, Fabio R. Kerbauy, MD17*, Lorena Figueredo-Pontes, MD, PhD18,19* and Eduardo M Rego, MD, PhD19,20

1Department of Genetic, Federal University of Pernambuco, Recife - PE, AC, BRA
2Department of Experimental Hematology, University Medical Center Groningen, Groningen, Netherlands
3Division of Hematology, Department of Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil
4Department of Internal Medicine, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil
5Federal University of Pernambuco, Recife, Pe, BRA
6Genetics postgraduate program, Biosciences Center, Federal University of Pernambuco, Recife, Brazil
7Cancer & Pharmaceutical Sciences, King's College London, London, United Kingdom
8AC Camargo, Sao Paulo, BRA
9Department of Genetics, Federal University of Pernambuco, Recife, BRA
10Department of Hematology, University Medical Center - Groningen, Groningen, Netherlands
11Department of Hematology, Cancer Research Center Groningen, University Medical Center Groningen, Groningen, Netherlands
12Department of Internal Medicine, University of Pernambuco and Fundação HEMOPE, Recife, Brazil
13Hematology Division, University Hospital of the Federal University of Rio Grande do Sul, Porto Alegre, Brazil
14Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil
15Hematology Division, University Hospital of the Federal University of Paraná, Curitiba, Brazil
16Hematology Division, Federal University of Minas Gerais, Belo Horizonte, Brazil
17Federal University of Sao Paulo, Sao Paulo, Brazil
18Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil
19Center for Cell-based Therapy and Regional Hemotherapy Center, University of Sao Paulo at Ribeirao Preto Medical School, Ribeirao Preto, Brazil
20Medical Research Laboratory on Molecular Hematology (LIM-31), University of São Paulo, Sao Paulo, Brazil

Jacob Higgins, PhD1*, Megan Othus, PhD2, Laura W. Dillon, PhD, DABMGG3*, Thomas H. Smith, PhD1*, Elizabeth Schmidt, MS1*, Jeffry Yaplee, BA1*, Fang Yin Lo, PhD1*, Charles C. Valentine III, MS1*, Jesse J. Salk, MD, PhD1, Brent L. Wood, MD, PhD4, Christopher S. Hourigan, DM DPhil3 and Jerald P. Radich, MD5

1TwinStrand Biosciences, Seattle, WA
2Division of Public Health, Fred Hutchinson Cancer Research Center, Seattle, WA
3Laboratory of Myeloid Malignancies, Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD
4Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
5Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA

*signifies non-member of ASH