-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

322. Disorders of Coagulation or Fibrinolysis: Clinical and Epidemiological: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Monday, December 13, 2021: 6:00 PM-8:00 PM
Hall B5, Level 1, Building B (Georgia World Congress Center)

Angela C. Weyand, MD1, Martin Chandler2*, Carol Fedor, RN2*, Kenneth D. Friedman, MD3, Sweta Gupta, MD4*, Kristina M. Haley, DO5, Chunla He2*, Nikki Hirsh2*, Salley Pels, MD6, Jonathan C. Roberts, MD7, Tung T. Wynn, MD8 and Robert F. Sidonio Jr., MD, MSc9

1Pediatrics, University of Michigan Medical School, Ann Arbor, MI
2American Thrombosis and Hemostasis Network, Rochester, NY
3Versiti BloodCenter of Wisconsin, Milwaukee, WI
4Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
5The Hemophilia Center, Oregon Health Science University, Portland, OR
6Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI
7Bleeding & Clotting Disorders Institute, Peoria, IL
8University of Florida, Gainesville, FL
9Hemophilia of Georgia Center for Bleeding and Clotting Disorders, Emory University, Decatur, GA

Robert F. Sidonio Jr., MD, MSc1, Christine Knoll2, Flora Peyvandi3,4*, Oleksandra Stasyshyn, MD, PhD5*, Ali Bulent Antmen6*, Seoh Leng Yeoh7*, Darintr Sosothikul8*, Caterina Maggiore9*, Werner Engl10*, Geoffrey Allen11* and Srilatha Tangada11

1Aflac Cancer and Blood Disorders Center, Emory University, Atlanta, GA
2Phoenix Children's Hospital, Phoenix, AZ
3Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
4Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy
5Academy of Medical Sciences of Ukraine, Lviv, Ukraine
6Acibadem Adana Hospital, Adana, Turkey
7Department of Pediatrics, Hospital Pulau Pinang, Penang, Malaysia
8Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
9IQVIA, Milan, Italy
10Baxalta Innovations GmbH, a Takeda company, Vienna, Austria
11Takeda Development Center Americas, Inc., Cambridge, MA

Robert F. Sidonio Jr., MD, MSc1, Alexis A. Thompson, MD, MPH2, Flora Peyvandi3,4*, Canan Albayrak5*, Seoh Leng Yeoh6*, Joyce Lam7*, Caterina Maggiore8*, Werner Engl9*, Geoffrey Allen10* and Srilatha Tangada10

1Aflac Cancer and Blood Disorders Center, Emory University, Atlanta, GA
2Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
3Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
4Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy
5Department of Pediatric Hematology, Ondokuz Mayıs University, Samsun, Turkey
6Department of Pediatrics, Hospital Pulau Pinang, Penang, Malaysia
7KK Women's and Children's Hospital, Singapore, Singapore
8IQVIA, Milan, Italy
9Baxalta Innovations GmbH, a Takeda company, Vienna, Austria
10Takeda Development Center Americas, Inc., Cambridge, MA

Monet Howard1*, Derrick McKinley2*, Fabian Sanabria3*, Richard H. Ko, MD, MHS, MS2 and Francis Nissen3*

1F. Hoffmann-La Roche Ltd, Mississauga, ON, Canada
2Genentech, Inc., South San Francisco, CA
3F. Hoffmann-La Roche Ltd, Basel, Switzerland

Robert Klamroth1*, Karin Kurnik2*, Swee Wenning3*, Carmen Escuriola-Ettingshausen4*, Stephan Regensburger5*, Leilei Tang6*, Joan Gu7*, Randy Guerra8* and Johannes Oldenburg9

1Department for Internal Medicine, Vascular Medicine and Haemostaseology, Vivantes Klinikum im Friedrichshain, Berlin, Germany
2Dr. von Haunersches Kinderspital Klinikum der Universität München, Munich, Germany
3SRH Kurpfalzkrankenhaus, Heidelberg, Germany
4Hämophilie-Zentrum Rhein Main GmbH, Moerfelden-Walldorf, Germany
5Takeda Pharma Vertrieb GmbH & Co. KG, Berlin, Germany
6Takeda Pharmaceuticals International AG, Zürich, Switzerland
7Takeda Development Center Americas, Inc., Lexington, MA
8Takeda Pharmaceuticals, Cambridge, MA
9Institute for Experimental Hematology and Transfusion Medicine, Bonn University Clinic, Bonn, Germany

Claire Anne Murphy, MB1,2,3*, Elaine Neary, PhD4,5*, Barry Kevane, PhD3,6, Daniel O'Reilly, MB2*, John O'Loughlin, MSc7*, Afif EL-Khuffash, MD1,2*, Patricia Maguire, PhD3*, Fionnuala Ni Ainle, MD, PhD3,8,9 and Naomi McCallion, MD1,2*

1Department of Paediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland
2Department of Neonatology, Rotunda Hospital, Dublin, Ireland
3Conway-SPHERE Research Group, University College Dublin, Dublin, Ireland
4Department of Neonatology, Liverpool Women's Hospital, Liverpool, United Kingdom
5Department of Health and Life Sciences, University of Liverpool, Liverpool, Ireland
6Department of Haematology, Mater Misericordiae University Hospital, Dublin, Ireland
7Department of Laboratory Medicine, Rotunda Hospital, Dublin, Ireland
8School of Medicine, University College Dublin, Dublin, Ireland
9Department of Haematology, Mater Misericordiae University Hospital and Rotunda Hospital, University College Dublin, Dublin, Ireland

Kim Mauer, MD1*, Travis Helm2*, Tyler W. Buckner3, Corey Macgregor2*, Judith A. Boice, PhD2, Frank Cerasoli, PhD2,4*, Tahmid Khan, MPH4* and Charles Argoff, MD5*

1Oregon Health and Science University, Portland, OR
2Tremeau Pharmaceuticals, Inc., Concord, MA
3Divisions of Hematology and Pediatric Hematology/Oncology, Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, CO
4RxMedical Dynamics, LLC, New York, NY
5Albany Medical Center, Albany, NY

Koichiro Yoneyama1*, Kazuo Tokuda, PhD2*, Tetsuhiro Soeda, PhD2*, Tomohisa Saito, PhD1* and Midori Shima, MD, PhD3

1Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
2Chugai Pharmaceutical Co., Ltd., Kamakura, Japan
3Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Japan

Kelsey Uminski, MD1, Yan Xu, MD1*, Amin Zahrai, MSc2*, Amanda Hodgson2*, Lisa Duffett, MD1,3*, Alan Tinmouth, MD, MSc1,3* and Roy Khalife, MD1,3

1Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada
2University of Ottawa, Ottawa, ON, Canada
3Ottawa Hospital Research Institute, Ottawa, ON, Canada

Lorenzo G.R. Romano, MD1*, Viola J.F. Strijbis, MSc2*, Ka Lei Cheung2*, Ying Poi Liu, PhD3*, Andrew C. McCreary3*, Frank W.G. Leebeek1 and Mettine H.A. Bos, PhD4

1Dept. of Hematology, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands
2Div. Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, Netherlands
3uniQure Biopharma B.V., Amsterdam, Netherlands
4Div. Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center Einthoven Lab. for Experimental Vascular Med., Leiden, Netherlands

Roberta Gualtierotti1,2*, Carla Valsecchi, BSc3*, Chiara Suffritti3*, Eugenia Biguzzi, MD3*, Sara Arcudi, MD3*, Lucia Schiavone3* and Flora Peyvandi2,3

1Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy
2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy
3Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico di Milano, Milano, Italy

Radoslaw Kaczmarek, PhD1*, Thais Bertolini, PhD1*, Roland W Herzog, PhD1 and Alexandra Sherman, DVM2*

1Pediatrics, Indiana University School of Medicine, Indianapolis, IN
2Neurosurgery, University of Florida, Gainesville, FL

Guy Young, MD1,2, Steven W. Pipe, MD3, Cédric Hermans, MD, MRCP, PhD4, Manuel Carcao5, Giancarlo Castaman6*, Joanna A. Davis, MD7, Jonathan M. Ducore, MD, MPH8, Amy L. Dunn, MD9, Miguel A. Escobar, MD10*, Janna Journeycake, MD, MSCS11, Osman Khan, MD, MSc11*, Johnny Mahlangu, MD12, Shannon Meeks, MD13, Ismail Haroon Mitha, MD14*, Claude Négrier, MD15, Ulrike Nowak-Göttl, MD, PhD16*, Michael Recht17,18, Tammuella Chrisentery-Singleton, MD19*, Oleksandra Stasyshyn, MD, PhD20*, Kateryna V. Vilchevska, MD21*, Laura Villarreal Martinez, MD22*, Michael Wang, MD23, Jerzy Windyga, MD, PhD24*, W. Allan Alexander, MD25*, Ahmad Al-Sabbagh, MD26*, Daniel Bonzo, PhD26*, Christopher Macie, MD, MBA27*, Ian S. Mitchell, PhD27*, Thomas A. Wilkinson, PhD28* and Amy D. Shapiro29

1Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA
2Keck School of Medicine, University of Southern California, Los Angeles, CA
3University of Michigan, Ann Arbor, MI
4Cliniques Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
5The Hospital for Sick Children, Toronto, ON, Canada
6Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Florence, Italy
7Pediatric Hemophilia Treatment Center, University of Miami, Miami, FL
8UC Davis, Hemostasis and Thrombosis Center, Sacramento, CA
9Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH
10University of Texas Health Science Center at Houston, Houston, TX
11Oklahoma Bleeding and Clotting Disorders Center at OU Health, Oklahoma City, OK
12Hemophilia Comprehensive Care Center, University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South Africa
13Emory University and Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta, Atlanta, GA
14Lakeview Hospital, Benoni, South Africa
15Edouard Herriot University Hospital, Lyon, France
16Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel, Germany
17American Thrombosis and Hemostasis Network, Rochester, NY
18Oregon Health & Science University, Portland, OR
19Louisiana Center for Advanced Medicine, Slidell, LA
20Institute of Blood Pathology and Transfusion Medicine, Lviv, Ukraine
21National Specialized Children’s Hospital Okhmatdyt, Kyiv, Ukraine
22Dr. José Eleuterio González Monterrey University Hospital, Monterrey, NL, Mexico
23Hemophilia and Thrombosis Center, University of Colorado, Aurora, CO
24Department of Hemostasis Disorders and Internal Medicine, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
25Aoede Associates, Athens, TX
26LFB-USA, Inc., Framingham, MA
27HEMA Biologics, LLC, Louisville, KY
28GLOVAL LLC, Broomfield, CO
29Indiana Hemophilia and Thrombosis Center, Indianapolis, IN

Aisling Barrett, MB BCh BAO MRCPI1*, Catherine Bergin1*, Mary Byrne1*, Kevin Ryan, FRCPath1*, Niamh M O'Connell, MB, PhD, FRCPath1*, James S O'Donnell, MD, PhD1,2 and Michelle Lavin, MB, PhD, FRCPath1,2*

1National Coagulation Centre, St James's Hospital, Dublin 8, Ireland
2Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin 2, Ireland

Viridiana Cano1*, José Bartelt-Hofer2*, Wenruo Hu3*, Shauna Andersson, MD, PhD4*, Pronabesh Dasmahapatra4 and Sylvia Von Mackensen5*

1Sanofi Genzyme, Cambridge, MA
2Sanofi Genzyme, Chilly-Mazarin, France
3Sanofi, Beijing, China
4Sanofi, Cambridge, MA
5University of Hamburg, Hamburg, Germany

Chia-Yau Chang, MD1,2*, Shiue-Wei Lai, PhD3*, Mei-Mei Cheng, M.D.4*, Pei-Yi Lai, B.S.5*, Jung-Tzu Ku, M.S.6*, Shu-Hsia Hu, M.S.7*, Chen-Hua Tsai, M.D.5,8*, Chao-Neng Cheng, M.D.9*, Yen-Lin Liu, M.D., PhD2,10*, Jia-Ruey Tsai, M.D5,11* and Yeu-Chin Chen, MD7,12

1Division of Pediatric Hematology/Oncology, Hemophilia Center, Taipei Medical University Hospital, Taipei, Taiwan
2School of Medicine, Department of Pediatrics, Taipei Medical University, College of Medicine, Taipei, Taiwan
3Hemophilia Care and Research Center, Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, AL, Taiwan
4Department of Pediatircs, Cheng Hsin General Hospital, Taipei, Taiwan
5Hemophilia Center, Taipei Medical University Hospital, Taipei, Taiwan
6Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan
7Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan
8Division of Hematology/Oncology, Cheng Hsin General Hospital, Taipei city, Taiwan
9Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan
10Division of Pediatric Hematology/Oncology, Taipei Medical University Hospital, Taipei, Taiwan
11Division of Hematology/Oncology, Taipei Medical University Hospital, Taipei, Taiwan
12Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital (TSGH), Taipei, Taipei (City), Taiwan

Chia-Yau Chang, MD1,2*, Shiue-Wei Lai, PhD3*, Mei-Mei Cheng, M.D.4*, Jung-Tzu Ku, M.S.5*, Shu-Hsia Hu, M.S.6*, Jia-Ruey Tsai, M.D7,8*, Chen-Hua Tsai, M.D.7,9*, Pei-Yi Lai, B.S.7*, Yen-Lin Liu, M.D., PhD10*, Chao-Neng Cheng, M.D.11* and Yeu-Chin Chen, MD6,12

1School of Medicine, Department of Pediatrics, Taipei Medical University, College of Medicine, Taipei, Taiwan
2Division of Pediatric Hematology/Oncology, Hemophilia Center, Taipei Medical University Hospital, Taipei, Taiwan
3Hemophilia Care and Research Center, Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, AL, Taiwan
4Department of Pediatircs, Cheng Hsin General Hospital, Taipei, Taiwan
5Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan
6Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan
7Hemophilia Center, Taipei Medical University Hospital, Taipei, Taiwan
8Division of Hematology/Oncology, Taipei Medical University Hospital, Taipei, Taiwan
9Division of Hematology/Oncology, Cheng Hsin General Hospital, Taipei city, Taiwan
10Division of Pediatric Hematology/Oncology, Taipei Medical University Hospital, Taipei, Taiwan
11Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan
12Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital (TSGH), Taipei, Taipei (City), Taiwan

Anke Adenaeuer1,2*, Stefano Barco, MD, PhD1,3*, Alice Trinchero1,4*, Hanan Nazir5,6*, Sarah Krutmann1*, Chiara Ambaglio7*, Vincenzo Rocco8*, Ylenia Pancione8*, Luigi Tomao9*, Arlette Ruiz de Saez, MD10*, Marion Echenagucia10*, Friederike Haeuser11*, Karl J. Lackner1,11*, Heidi Rossmann1,11* and Bernhard Lämmle, MD1,12,13

1Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
2Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany
3Clinic of Angiology, University Hospital and University of Zurich, Zurich, Switzerland
4Department of Medical Oncology and Hematology, University Hospital and University of Zurich, Zurich, Switzerland
5Child Health Department, Sultan Qaboos University Hospital, muscat, Oman
6Department of Pediatrics, Alexandria Faculty of Medicine, Alexandria, Egypt
7Dipartimento Area Medica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
8Dipartimento di Medicina di Laboratorio, Azienda Ospedaliera G. Rummo, Benevento, Italy
9IRCCS Regina Elena National Cancer Institute, Roma, ITA
10Centro Nacional de Hemofilia, Banco Municipal de Sangre del Distrito Capital, Caracas, Venezuela (Bolivarian Republic of)
11Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
12Department of Hematology and Central Hematology Laboratory, Bern University Hospital, University of Bern, Bern, Switzerland
13Haemostasis Research Unit, University College London, London, United Kingdom

Tammuella Chrisentery-Singleton1*, W Allan Alexander, MD2*, Ahmad Al-Sabbagh, MD3*, Daniel Bonzo, PhD3*, Michael U. Callaghan, MD4, Miguel A. Escobar, MD5*, Adam Giermasz, MD, PhD6, Nikki Hirsh7*, Janna Journeycake, MD, MSCS8, Sonia Nasr9*, Doris V. Quon10 and Michael Recht11

1Pediatric Hematology, Louisiana Center for Advanced Medicine, Slidell, LA
2Aoede Associates, Athens, TX
3LFB-USA, Inc., Framingham, MA
4Division of Pediatric Hematology/Oncology, Central Michigan University SOM, Children’s Hospital of Michigan, Detroit, MI
5Department of Hematology, University of Texas Health Science Center, Houston, TX
6Hemophilia Treatment Center, University of California Davis, Sacramento, CA
7American Thrombosis And Hemostasis Network, Rochester, NY
8Jimmy Everest Center for Cancer and Blood Disorders, University of Oklahoma Health Sciences Center, Oklahoma City, OK
9GLOVAL, LLC, Broomfield, CO
10Los Angeles Orthopedic Hemophilia Treatment Center, Orthopedic Institute for Children, Los Angeles, CA
11American Thrombosis and Hemostasis Network, Rochester, NY

Mark Crowther, MD1 and William Shi, MD2*

1McMaster University and St Joseph's Hospital, Hamilton, ON, Canada
2Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada

Beth Boulden Warren, MD MS MSCS1, Joseph Mah1*, Niamh Mah, BS1*, Hana Durkee, BS1*, Sharon Funk, DPT1*, Marilyn J Manco-Johnson, MD1 and James Carollo, PhD2*

1Hemophilia and Thrombosis Center, University of Colorado Anschutz Medical Campus, Aurora, CO
2Children's Hospital Colorado, Center for Gait and Movement Analysis, University of Colorado Anschutz Medical Campus, Aurora, CO

Meera Sridharan, MD, PhD1,2, Dawn M Inman, R.N.1,2* and Rajiv K. Pruthi, M.B.B.S1,2

1Division of Hematology, Mayo Clinic, Rochester, MN
2Mayo Comprehensive Hemophilia Center, Mayo Clinic, Rochester, MN

Allison P. Wheeler, MD1, Miguel A. Escobar, MD2*, Susan Kearney, MD3, Janice M. Staber4, Adam R. Wufsus, PhD5*, Vlady Ostrow, DO6* and Steven R. Lentz, MD, PhD7

1Vanderbilt University Medical Center, Nashville, TN
2University of Texas Health Science Center, Houston, TX
3Children's Minnesota, Minneapolis, MN
4University of Iowa Stead Family Children’s Hospital, Iowa City, IA
5Novo Nordisk, Plainsboro, NJ
6Novo Nordisk Inc., Plainsboro, NJ
7University of Iowa, Iowa City, IA

Hyunji Kim, MD and Seongsoo Jang, M.D., Ph.D.

Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of (South)

*signifies non-member of ASH