-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614.P1.40 614. Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster I

Program: Oral and Poster Abstracts
Type: Poster
Saturday, December 11, 2021: 5:30 PM-7:30 PM
Hall B5, Level 1, Building B (Georgia World Congress Center)

Josep-Maria Ribera, MD, PhD1, Olga Garcia2*, Jordi Ribera, PhD3*, Pau Montesinos, PhD, MD4*, Isabel Cano, MD5*, Pilar Martínez, MD6*, Jordi Esteve, MD, PhD7, Daniel Esteban8*, María García-Fortes9*, Natalia Alonso10*, José González-Campos, MD11*, Arancha Bermúdez, MD12*, Anna Torrent3*, Eulàlia Genescà, PhD13*, Santiago Mercadal, MD14*, Joaquín Martínez-López15* and Ramon Garcia-Sanz, MD16

1Hematology Department, ICO Badalona, Germans Trias i Pujol University Hospital. Universitat Autònoma de Barcelona. Josep Carreras Leukemia Research Institute, Badalona, Spain
2Department of Hematology, ICO-Hospital Germans Trias i Pujol, Josep Carreras Leukaemia Research Institute (IJC), Institut Germans Trias i Pujol (IGTP), Universitat Autònoma de Barcelona, Badalona, Spain
3Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Research Institute. Universitat Autònoma de Barcelona, Badalona, Spain
4Hospital Universitario y Politécnico Le Fe, Valencia, Spain
5Hospital Universitario y Politécnico La Fe, Valencia, Spain
6Hospital Doce De Octubre, Madrid, ESP
7Hospital Clínic, Barcelona, Spain
8Hospital Clínic i Provincial de Barcelona, Barcelona, Spain
9Hospital Universitario Virgen De La Victoria, MáLaga, ESP
10Complejo Hospitalario Universitario. Santiago de Compostela, Santiago de Compostela, Spain
11Hematology Department, Hospital Universitario Virgen del Rocio. Instituto de Biomedicina de Sevilla (IBIS)/CSIC/CIBERONC. Universidad de Sevilla, Sevilla, Spain
12Hematology Department, University Hospital "Marqués de Valdecilla", Santander, Spain
13Institut d’Investigació contra la Leucemia Josep Carreras (IJC), Campus ICO (Institut Català d’Oncologia)-Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona., Badalona, Spain
14ICO-Hospital Duran i Reynals, Hospitalet De Llobregat, Spain
15Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
16Hospital Universitario de Salamanca (HUS/IBSAL), CIBERONC and Center for Cancer Research-IBMCC (USAL-CSIC), Salamanca, Spain

Franco Locatelli, MD, PhD1, Gerhard Zugmaier, MD, PhD2, Carmelo Rizzari, MD3*, Joan D Morris4*, Bernd Gruhn5*, Thomas Klingebiel6, Rosanna Parasole7*, Christin Linderkamp8*, Christian Flotho, MD9*, Arnaud Petit, MD, PhD10*, Concetta Micalizzi, MD11*, Yi Zeng12, Deepali Dilip Pilankar13*, William N Kormany, MD14*, Cornelia Eckert, PhD15*, Anja Moericke, MD16*, Mary Sartor, BSc, PhD17*, Ondrej Hrusak, MD, PhD18, Christina Peters19*, Vaskar Saha, MD, PhD20,21*, Luciana Vinti, MD22* and Arend von Stackelberg, MD23

1Department of Hematology/Oncology and Cell and Gene Therapy, Bambino Gesù Children’s Hospital, Sapienza, University of Rome, Rome, Italy
2Amgen Research (Munich), Munich, Germany
3Pediatric Hematology-Oncology Unit, MBBM Foundation, ASST Monza, University of Milano-Bicocca, Monza, Italy
4Amgen Inc., Thousand Oaks, CA
5Universitaetsklinikum Jena, Jena, Germany
6Universitätsklinikum Frankfurt am Main, Frankfurt, Germany
7Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon, Napoli, Italy
8Medizinische Hochschule Hannover, Hanover, Germany
9Universitätsklinikum Freiburg, Freiburg, Germany
10Department of pediatric Hematology and Oncology, Hôpital Armand Trousseau, APHP, Sorbonne Université, Paris, France
11Istituto Ospedaliero Giannina Gaslini, Genova, Italy
12Amgen Inc, Thousand Oaks, CA
13IQVIA Inc., Durham, NC
14Global Patient Safety, Amgen Inc, Thousand Oaks, CA
15Charité Campus Virchow-Klinikum Pädiatrie m.S. Onkologie/Hämatologie, Berlin, Germany
16Univ.-Klinikum Schleswig-Holstein, Kiel, Germany
17Westmead Hospital, Sydney, NSW, Australia
18Charles University Prague University Hospital, Prague, Czech Republic
19St Anna Children's Hospital, Vienna, Austria
20Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom
21Tata Translational Cancer Research Centre, Tata Medical Center, Kolkata, India
22Department of Hematology/Oncology and of Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Sapienza, University of Rome, Rome, Italy
23Charite Universitaetsmedizin CVK Berlin, Berlin, Germany

Nicolas Boissel, MD, PhD1, Francoise Huguet, MD2*, Carlos Graux3*, Yosr Hicheri4*, Patrice Chevallier, MD5, Rathana KIM, PharmD6*, Marie Balsat, MD7*, Thibaut Leguay, MD8*, Mathilde Hunault, MD PhD9*, Sébastien Maury10*, Anne Thiebaut-Bertrand11*, Martine Escoffre-Barbe, MD12*, Thomas Cluzeau, MD, PhD13, Alban Villate, MD14*, Florence Pasquier, MD, PhD15*, Laure Farnault, MD16*, Florence Van Obbergh17*, Philippe Rousselot18*, Yves Chalandon, MD19, Eric Delabesse, PharmD, PhD20*, Cedric Pastoret, MD21*, Emmanuelle Clappier, PhD, PharmD22*, Veronique Lheritier23* and Herve Dombret, MD, PhD24

1St-Louis Hospital, APHP, Adolescents and Young Adults Hematology Department, Paris, France
2Department of Hematology, Institut Universitaire du Cancer-Oncopole CHU de Toulouse, Toulouse, France
3Université Catholique de Louvain, CHU UCL Namur (Godinne), Yvoir, Belgium
4Institut Paoli-Calmettes, MARSEILLE, France
5Hotel Dieu, CHU de Nantes, Service d'hématologie, Nantes, France
6Hematology Laboratory, Hopital Saint-Louis, Paris, France
7Service Hematologie, Centre Hospitalier Lyon Sud, Lyon, France
8Hematology Clinic, Bordeaux University Hospital, Pessac, France
9Clinical Hematology, Angers University Hospital, Angers, France
10AP-HP, Hôpital Henri Mondor, Service d’hématologie clinique, Créteil, France
11Department of Hematology, CHU-Grenoble Onco-Hematologie, Grenoble, France
12Hematology department, CHU Rennes, Rennes, France
13Department of Clinical Hematology, CHU De Nice, Nice, France
14Service d'hématologie et thérapie cellulaire, Hôpital Bretonneau, CHRU de Tours, Tours, France
15Gustave Roussy, Département clinique d'hématologie, INSERM UMR1170, Villejuif, FRA
16Service d'hématologie clinique et de thérapie cellulaire, Assistance Publique des Hôpitaux de Marseille, Centre Hospitalier Universitaire La Conception, Marseille, France
17CH Jolimont, Hematology Department, La Louviere, BEL
18Hematology department, Hôpital André Mignot, Versailles, France
19Department of Hematology, Geneva University Hospital, Geneva, Switzerland
20Laboratoire d'hématologie, CHU de Toulouse - Institut Universitaire du Cancer De Toulouse-Oncopole, Toulouse cedex9, France
21Laboratoire d'Hematologie, INSERM U1236 /hematology laboratory/university hospital of Rennes, RENNES, FRA
22Hematology Laboratory, Hôpital Saint Louis, Paris, France
23Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL), Centre Hospitalier Lyon Sud, Lyon, France
24Hematology, Hôpital Saint-Louis, Paris, France

Nicholas Short, MD1, Hagop Kantarjian, MD2, Farhad Ravandi, MB Bs1, Xuelin Huang, PhD3*, Philip A. Thompson2, Alessandra Ferrajoli, MD2, Tapan M. Kadia, MD4, Nitin Jain, MD2, Yesid Alvarado, MD2, Musa Yilmaz, MD2, Joseph D. Khoury5, Jeffrey L. Jorgensen, MD, PhD5*, Sa A Wang, MD5*, Steven Kornblau, MD2, Marina Konopleva, MD, PhD2, Guillermo Garcia-Manero, MD2, Rebecca Garris, MSc2*, Heather M Schroeder2*, Anna Milton2*, Juan Rivera2*, Glenda Banks2* and Elias J. Jabbour2

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
5Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Shaun Fleming, MBBS,1*, John Reynolds, PhD2*, Ashish Bajel, MBBS, FRACP, FRCPA3,4, Nicola Venn, BSc5*, John Kwan, MBBS, FRACP, FRCPA6*, John Moore, MD7, David T Yeung, BSc, PhD, FRACP, FRCPA, MBBS8, Nalini Pati, MBBS, FRACP, FRCPA, DCH, MD, DNB9,10*, Michael F. Leahy, FRACP, FRCPath, FRCP11, Joanna Nkyekyer12*, Emma Verner, MBBS13*, Leanne Berkahn, MD14*, Rosemary Sutton, BSc MSc PhD5*, Andrew H. Wei, MBBS, PhD15,16 and Matthew Greenwood, MBBS, FRACP, FRCPA17*

1Department of Clinical Haematology, The Alfred Hospital, Melbourne, Australia
2Biostatistics Consulting Platform, Alfred Health and Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, VIC, Australia
3Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Australia
4Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia
5Children's Cancer Institute Australia, University of NSW, Randwick, NSW, Australia
6Westmead Hospital, Sydney, NSW, Australia
7Haematology and Bone Marrow Transplantation, St Vincent's Hospital, Silver Spring, MD
8Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia
9ANU Medical School, Canberra, Australia
10The Canberra Hospital, Canberra, Australia
11Department of Haematology, Royal Perth Hospital, Perth, Australia
12Australasian Leukaemia and Lymphoma Group, Melbourne, Australia
13Concord Repatriation General Hospital, Concord, NSW, Australia
14Department of Haematology, Auckland City Hospital, Auckland, New Zealand
15Department of Clinical Haematology, The Alfred Hospital, Melbourne, VIC, Australia
16Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
17Department of Haematology, Royal North Shore Hospital, Sydney, NSW, Australia

Michael J. Burke, MD1,2, David S. Ziegler, MBBS, FRACP, MD 3*, Francisco Bautista4*, Andishe Attarbaschi, MD5*, Lia Gore, MD6, Franco Locatelli, MD, PhD7, Maureen M. O'Brien, MD8, Melinda Pauly, MD9,10*, Mihaela Obreja, PhD11*, Christopher L. Morris, PhD, MD12* and Andre Baruchel, MD13

1Children’s Hospital of Wisconsin / Medical College of Wisconsin, Milwaukee, WI
2Medical College of Wisconsin, Milwaukee, WI
3Sydney Children's Hospital, Randwick, NSW, Australia
4Hospital Niño Jesus, Madrid, Spain
5St Anna Kinderspital and Children’s Cancer Research Institute, Vienna, Austria
6University of Colorado, Children’s Hospital Colorado, Aurora, CO
7IRCCS Bambino Gesù Children’s Hospital, Rome, Sapienza, University of Rome, Rome, Italy
8Cincinnati Children's Hospital Medical Center, Cincinnati, OH
9Emory University School of Medicine, Atlanta, GA
10Children’s Healthcare of Atlanta, Atlanta, GA
11Amgen, Inc., Thousand Oaks, CA
12Amgen Inc, Thousand Oaks, CA
13Hôpital Universitaire Robert Debré (APHP) and Université de Paris, Paris, France

Ryo Nakagawa1,2*, Yoriko Saito, MD1, Shinsuke Takagi, MD3*, Sadaaki Takata4*, Hanae Amitani4*, Mikiko Endo4*, Naoyuki Uchida, MD, PhD3, Yukihide Momozawa, DVM, Ph.D4*, Shuichi Taniguchi, MD, PhD3, Hideo Harigae, MD, PhD2 and Fumihiko Ishikawa, MD, PhD1

1Laboratory for Human Disease Models, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
2Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan
3Department of Hematology, Toranomon Hospital, Tokyo, Japan
4Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Nitin Jain, MD1, Elias J. Jabbour2, Marina Konopleva, MD, PhD1, Naveen Pemmaraju, MD1, Philip A. Thompson1, Nicholas Short, MD3, Tapan M. Kadia, MD4, Gautam Borthakur, MD5, Naval Daver, MD6, Courtney D. DiNardo, MD, MSCE1, Ibrahim Aldoss, MD7, Robin Cook, RN1*, Farhad Ravandi, MB Bs3 and Hagop Kantarjian, MD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX
3Department of Leukemia, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
4Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
5MD Anderson Cancer Center, The University of Texas, Houston, TX
6MD Anderson Cancer Center, Houston, TX
7Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA

Sai Lon Wann, MBBS, MRCP1*, Tertius Tuy, MD2*, Victor Ling Wei Teik, MD, MRCP3*, Christian Gallardo4*, Lip Leong Chong, MD, MRCP5*, Samuel Sherng Young Wang, MD4*, Nurul Aidah Abdul Halim, MBBS6*, Yar Myint Zay6*, Allen Eng Juh Yeoh, MD7, Sampath Venkata Sreekanth4*, Chin Hin Ng, MD, MRCP3,8*, Michelle Poon, MBBS, MRCP, FRCPath9*, Gee Chuan Wong, MBBS2 and Melissa Ooi, MB BCh, BAO, MRCP(I), FRCPath, PhD10*

1National University Cancer Institute, Singapore (NCIS), National University Hospital, Singapore, SGP
2Haematology, Singapore General Hospital, Singapore, Singapore
3National University Cancer Institute, Singapore (NCIS), National University Hospital, Singapore, Singapore
4Tan Tock Seng Hospital, Singapore, Singapore
5Department of Haematology, Tan Tock Seng Hospital, Singapore, Singapore
6Singapore General Hospital, Singapore, Singapore
7Division of Haematology-Oncology, Department of Paediatrics, National University Hospital Singapore, Singapore, Singapore
8National University Cancer Institute, National University Hospital, Singapore, Singapore, Singapore
9National University Cancer Insitute, Singapore, National University Hospital, Singapore, Singapore
10Department of Haematology Oncology, National University Cancer Institute, Singapore, National University Health System, Singapore, Singapore

Sangeetha Venugopal, MD1, Hagop Kantarjian, MD1, Nicholas Short, MD1, Philip A. Thompson2, Naveen Pemmaraju, MD1, Nitin Jain, MD1, William G. Wierda1, Gautam Borthakur, MD1, Guillermo Montalban-Bravo, MD1, Farhad Ravandi, MB Bs1, Guillermo Garcia-Manero, MD1, Tapan M. Kadia, MD1, Maro Ohanian, DO1*, Kelly S. Chien, MD1, Jennifer Thankachan1*, Benjamin Nwakanme3*, Rebecca Garris, MSc1* and Elias J. Jabbour1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
3The University of Texas MD Anderson Cancer Center, Houston, TX

Jimei Zhao1,2*, Masahiro Ueki, MD1*, Saori Sawai, MD1*, Minako Sugiyama, MD1*, Yukayo Terashita, MD1*, Shinsuke Hirabayashi, MD1*, Yuko Cho, MD1*, Yoichi Tanaka, PhD3* and Atsushi Manabe, MD, PhD1

1Department of Pediatrics, Hokkaido University Hospital, Sapporo, Japan
2Department of Pediatric dentistry, Hokkaido University Hospital, Sapporo, Japan
3National Institute of Health Sciences, Tokyo, Japan

Sean P Rinella, MPH1, Haley C Bell1*, Lei Shi, PhD1*, Lixin Rui, PhD2 and Christian M. Capitini, MD3

1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI
2Department of Medicine and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI
3Department of Pediatrics and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI

*signifies non-member of ASH