-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

704A.O4.6 704. Cellular Immunotherapies: Cellular Therapies-Immune Interactions, Lineage Switching and CNS targets

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Clinical Trials, Lymphoid Leukemias, ALL, Biological therapies, Workforce, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Diversity, Equity, Inclusion, and Accessibility (DEI/DEIA) , Diseases, Therapies, Lymphoid Malignancies
Saturday, December 11, 2021: 2:00 PM-3:30 PM
Hall A1 (Georgia World Congress Center)
Moderators:
Susanne H.C. Baumeister, MD, Harvard Medical School, Boston Children's Hospital, Dana-Farber Cancer Institute and Michael R Verneris, MD, University of Colorado At Denver
Disclosures:
Baumeister: Takeda: Other: Current employment and equity holder in publicly-traded company (Spouse); Alexion Pharmaceuticals: Other: Ended employment in the past 24 months (Spouse); AstraZeneca: Other: Current equity holder in publicly-traded company (Spouse).
2:00 PM

Melody Smith, MD, MS1, Anqi Dai, MS2*, Guido Ghilardi, MD3*, Kimberly Amelsberg3*, Sean M Devlin, PhD4*, Raymone Pajarillo, MS3*, John B Slingerland5,6*, Silvia Beghi7*, Pamela S Herrera8*, Paul A Giardina6*, Annelie Clurman, BA6*, Emmanuel A Dwomoh8*, Gabriel K Armijo8*, Antonio L.C. Gomes, PhD9*, Eric R Littmann, BA10*, Jonas Schluter11*, Emily Fontana, BA12*, Ying Taur, MD, MPH13*, Jae H Park, MD14, Maria Lia Palomba15, Elizabeth Halton16*, Josel D Ruiz, MPH17*, Tania Jain, MD18, Martina Pennisi, MD19*, Aishat Olaide Afuye, BA20*, Miguel-Angel Perales, MD21, Craig W. Freyer, PharmD22*, Alfred L Garfall, MD23, Shannon H Gier, BS3*, Sunita Nasta, MD24,25, Daniel J Landsburg, MD24, James N Gerson, MD24, Jakub Svoboda, MD24, Justin Cross, PhD26*, Elise A Chong, MD24, Sergio A Giralt, MD27, Saar Gill, MD, PhD28, Isabelle C Riviere, PhD29, David L Porter, MD30, Stephen J Schuster, MD31, Michel Sadelain, MD, PhD32, Noelle V Frey, MD, MS33, Renier J Brentjens, MD, PhD14, Carl H June, MD3,34, Eric G Pamer, MD10*, Jonathan U Peled, MD35, Marco Ruella, MD36, Marcel van den Brink, MD, PhD17 and Andrea Facciabene, PhD37*

1Adult Bone Marrow Transplant Service and Cellular Therapeutics Center, Memorial Sloan-Kettering Cancer Center, New York, NY
2MSKCC, New York, NY
3Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
4Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
5MSKcc, New York
6Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, NY
7University of Pennsylvania, Philadelphia, PA
8Memorial Sloan Kettering Cancer Center, New York, NY
9Xbiome, New York
10The Duchossois Family Institute, University of Chicago, Chicago, IL
11Department of Microbiology, New York University School of Medicine, New York
12Sloan Kettering Institute, Lucille Castori Center for Microbes, Inflammation & Cancer, Memorial Sloan Kettering Cancer Center, New York, NY
13Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
14Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
15Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
16Cellular Therapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY
17Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY
18Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
19Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
20Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
21Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY
22Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA
23Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
24Department of Medicine, Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA
25The University of Pennsylvania, Philadelphia, PA
26Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan-Kettering Cancer Center, New York, NY
27Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
28Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
29Cell Therapy and Cell Engineering Facility, Memorial Sloan Kettering Cancer Center, New York, NY
30Division of Hematology-Oncology/Department of Medicine, University of Pennsylvania, Philadelphia, PA
31Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA
32Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY
33Abramson Cancer Center, University of Pennsylvania, Narberth, PA
34Center for Cellular Immunotherapies (CCI), The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA
35Adult Bone Marrow Transplant Service, MSKCC, New York, NY
36Division of Hematology-Oncology and Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
37Center for Cellular Immunotherrapy (CCI), University of Pennsylvania, Philadelphia, PA

2:15 PM

Thomas Gastinne, MD1*, Amandine Le Bourgeois, MD2*, Marianne Coste-Burel, MD, PhD3*, Thierry Guillaume, MD, PhD4*, Pierre Peterlin5*, Alice Garnier, MD2*, Berthe-Marie Imbert6*, Thomas Drumel, PharmD3*, Béatrice Mahé, MD7*, Viviane Dubruille, MD2*, Nicolas Blin, MD2*, Anne Lok, MD2*, Cyrille Touzeau, MD, PhD8*, Benoit Tessoulin, MD, PhD9*, Maxime Jullien, MD2*, Sophie Vantyghem, MD2*, Marie C Bene, PharmSci, PhD10*, Philippe Moreau, MD, PhD11*, Steven Le Gouill12 and Patrice Chevallier, MD13

1Clinical Hematology, University Hospital of Nantes,, Nantes Cedex 1, France
2Clinical Hematology, Nantes University Hospital, Nantes, France
3Virology, Nantes University Hospital, Nantes, France
4CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France
5Clinical Hematology, HOPITAL HOTEL DIEU ET HME, NANTES CEDEX 1, France
6Virology, Nantes University Hospital, NANTES, France
7Centre Hospitalier Universitaire de Nantes, Nantes, France
8Hématologie, CHU de Nantes, Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Nantes, France
9Université de Nantes, CNRS, INSERM, CRCINA, Nantes, France, Nantes, France
10Nantes University Hospital, Hematology Biology, Nantes, France
11Hematology Department Nantes University Hospital, Nantes University, Nantes, France
12Service d’hématologie clinique du CHU de Nantes, INSERM CRCINA Nantes-Angers, NeXT Université de Nantes, Nantes, France
13D'Hematologie, Nantes University Hospital, Nantes, France

2:30 PM

Wei Jiang, MBBS, BSc, BA1*, Gaurav Sutrave, BSc (Med), MBBS, FRACP, FRCPA1,2*, Selmir Avdic, PhD1*, Leighton Edward Clancy, BSc, PhD3*, Shafqat Inam, MBBS, FRACP, FRCPA2*, Elissa Atkins, RN2*, Caroline M Bateman, MBBS FRACP FRCPath MRCP PhD4, Adrian Gabriel Selim, MBBS5*, Vicki Antonenas, BSc3*, Janine Street, BSc MSc (Hons)1*, Renee Simms, BSc1*, Peter J. Shaw, MA, FRACP6, David Ritchie, MB ChB, PhD, FRACP, FRCPA5, Emily Blyth, B. Med(Hons), FRACP, FRCPA, PhD1,2* and David J Gottlieb, MD, MBBS, FRACP, FRCPA7,8*

1Westmead Institute for Medical Research, The University of Sydney, Sydney, Australia
2Department of Haematology, Westmead Hospital, Westmead, NSW, Australia
3Westmead Hospital, Sydney Cellular Therapies Laboratory, Sydney, Australia
4Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia
5Haematology Department, Royal Melbourne Hospital, Melbourne, VIC, Australia
6The Children's Hospital at Westmead, The Sydney Children's Hospitals Network, Westmead, Australia
7Westmead Hospital, University of Sydney, Sydney, Australia
8Department of Haematology, Westmead Hospital, Sydney, Australia

2:45 PM

Adam J. Lamble, MD1, Regina M. Myers, MD2, Agne Taraseviciute, MD3*, Samuel John, MD4*, Bonnie Yates, NP5*, Seth M. Steinberg, PhD6*, Jennifer Sheppard4*, Alexandra E. Kovach, M.D.7*, Brent L. Wood, MD, PhD7, Michael Borowitz, MD, PhD8, Maryalice Stetler-Stevenson, MD, PhD9*, Constance M. Yuan, MD, PhD9*, Vinodh Pillai, MD, PhD10, Toni Foley5*, Perry Chung, MD2*, Lee Chen11*, Daniel W. Lee, MD12, Colleen Annesley, MD13, Amanda M. DiNofia, MD, MSCE2*, Stephan A. Grupp, MD, PhD2, Michael R Verneris, MD14, Lia Gore, MD15, Theodore W. Laetsch, MD2*, Deepa Bhojwani, MD16, Patrick A. Brown, MD17, Michael A. Pulsipher, MD11, Susan R. Rheingold, MD2, Rebecca A Gardner, MD13 and Nirali N. Shah, MD18

1Division of Hematology and Oncology, Seattle Children's Hospital, Seattle, WA
2Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
3Division of Hematology, Oncology, Blood and Marrow Transplantation, Children’s Hospital Los Angeles, Los Angeles, CA
4UT Southwestern, Dallas, TX
5Pediatric Oncology Branch, National Cancer Institute/NIH, Bethesda, MD
6Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD
7Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
8Departments of Pathology and Oncology, Johns Hopkins Hospital, Baltimore, MD
9Laboratory of Pathology, National Cancer Institute, Bethesda, MD
10Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA
11Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, CA
12University of Virginia, Charlottesville, VA
13Division of Hematology-Oncology, Seattle Children's Hospital, Seattle, WA
14Children's Hospital Colorado, University of Colorado At Denver, Aurora, CO
15Children's Hospital Colorado, University of Colorado, Aurora, CO
16Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Hospital of Los Angeles, Los Angeles, CA
17Division of Pediatric Oncology, Johns Hopkins Univ., Baltimore, MD
18Pediatric Oncology Branch, National Cancer Institute/Nih, Bethesda, MD

3:00 PM

Ying Liu, MD1*, Biping Deng, PhD2*, Bo Hu1*, Wenqun Zhang, MD1*, Qing Zhu1*, Yang Liu1*, Shan Wang1*, Pei Zhang1*, Junhan Yang1*, Qinlong Zheng3*, Xinjian Yu3*, Zifen Gao4*, Chunju Zhou5*, Wei Han6*, Alex Hong Chang, MD7* and Yonghong Zhang, MD1*

1Department of Pediatric Lymphoma, Beijing Boren Hospital, Beijing, China
2Cytology Laboratory, Beijing Boren Hospital, Beijing, China
3Medical Laboratory, Beijing Boren Hospital, Beijing, China
4Department of Pathology, Peking University Third Hospital, Beijing, China
5Department of Pathology, National Center for Children’s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China
6Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences /School of Basic Medicine, Beijing, China
7Clinical Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

3:15 PM

Matthew J. Frigault, MD1, Jorg Dietrich, MD PhD2*, Kathleen M.E. Gallagher, PhD3*, Irene Scarfò, PhD4, Mark Roschewski, MD5, Justin T Jordan, MD MPH6*, Deborah A. Forst, MD7*, Scott R Plotkin, MD PhD6*, Daniella Cook, BS8*, Keagan Casey, BS8*, Katelin Katsis, BS6*, Kevin Lindell, BS8*, Michael Trailor, BS8*, Nora Horick, MS6*, Steven McAfee, MD2*, Paul V O’Donnell, MD9*, Thomas R Spitzer, MD10, Bimalangshu R Dey, MD11, Zachariah Defilipp, MD11, Areej El-Jawahri, MD12, Tracy Batchelor, MD13, Marcela V. Maus, MD8 and Yi-Bin Chen, MD, MS14

1HCTCT, Mass General Hospital Cancer Center, Boston, MA
2Massachusetts General Hospital, Boston, MA
3Massachusetts General Hospital, Harvard Medical School, Charlestown, MA
4Massachusetts General Hospital, Charlestown, MA
5Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
6Mass General Cancer Center, Boston, MA
7Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA
8Cancer Center, Massachusetts General Hospital, Boston, MA
9Massachusetts General Hospital, Boston
10Department of Medicine, Bone Marrow Transplant Unit, Massachusetts General Hospital / Harvard Medical School, Boston, MA
11Massachusetts General Hospital / Harvard Medical School, Boston, MA
12Blood and Marrow Transplant Program, Massachusetts General Hospital, Allston, MA
13BWH Dept of Neurology, Boston, MA
14Hematopoietic Cell Transplant and Cellular Therapy Program, Massachusetts General Hospital, Needham, MA

*signifies non-member of ASH