Jacob P. Laubach^1*, Jonathan L. Kaufman, MD², Douglas W. Sborov, MD, MSc³, Brandi Reeves, MD⁴, Cesar Rodriguez⁵, Ajai Chari, MD^6*, Rebecca W. Silbermann, MD⁷, Luciano J. Costa, MD, PhD⁸, Larry D. Anderson Jr., MD, PhD⁹, Nitya Nathwani, MD¹⁰, Nina Shah, MD¹¹, Naresh Bumma, MD¹², Yvonne A. Efebera, MD, MPH¹³, Sarah A. Holstein, MD, PhD¹⁴, Caitlin Costello, MD¹⁵, Andrzej Jakubowiak¹⁶, Tanya M. Wildes, MD, MSc¹⁷, Robert Z. Orlowski¹⁸, Kenneth H. Shain, MD, PhD¹⁹, Andrew J. Cowan^20*, Huiling Pei, PhD^21*, Annelore Cortoos^22*, Sharmila Patel, PhD^22*, J Blake Bartlett, PhD²³, Jessica Vermeulen²⁴, Thomas S. Lin, MD, PhD²², Paul G. Richardson, MD²⁵ and Peter M. Voorhees, MD^26*

¹Dana-Farber Cancer Institute, Boston, MA
²Winship Cancer Institute, Emory University, Atlanta, GA
³Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT
⁴University of North Carolina – Chapel Hill, Chapel Hill, NC
⁵Wake Forest University School of Medicine, Winston-Salem, NC
⁶Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY
⁷Knight Cancer Institute, Oregon Health & Science University, Portland, OR
⁸University of Alabama at Birmingham, Birmingham, AL
⁹Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX
¹⁰Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope Comprehensive Cancer Center, Duarte, CA
¹¹Department of Medicine, University of California San Francisco, San Francisco, CA
¹²Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH
¹³OhioHealth, Columbus, OH
¹⁴Division of Oncology & Hematology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
¹⁵Moores Cancer Center, University of California San Diego, La Jolla, CA
¹⁶University of Chicago Medical Center, Chicago, IL
¹⁷Cancer & Aging Research Group, St. Louis, MO
¹⁸Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁹Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²⁰Division of Medical Oncology, University of Washington, Seattle, WA
²¹Janssen Research & Development, LLC, Titusville, NJ
²²Janssen Scientific Affairs, LLC, Horsham, PA
²³Janssen Research & Development, LLC, Raritan, NJ
²⁴Janssen Research & Development, Leiden, Netherlands
²⁵Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²⁶Levine Cancer Institute - Atrium Health, Charlotte, NC

Kaz Groen^1*, Claudia A.M. Stege, MD^2*, Kazem Nasserinejad, PhD^3*, Koen de Heer, MD, PhD^4*, Roel J.W. Van Kampen, MD, PhD⁵, Maria B.L. Leijs, MD^6*, Noortje Thielen, MD, PhD^7*, Matthijs Westerman, MD^8*, Ka Lung Wu, MD⁹, Inge Ludwig, MD, MSc^10*, Djamila Issa^11*, Gerjo A. Velders, PhD, MD^12*, Marie-Christiane Vekemans^13*, Niels W.C.J. van de Donk¹⁴, Gert-Jan Timmers^15*, Pieter Sonneveld¹⁶, Maarten R. Seefat, MD^17*, Fransien Croon-de Boer^18*, Lidwine W. Tick, MD, PhD¹⁹, Ellen van der Spek, MD, PhD^20*, Esther G.M. De Waal, MD^21*, Maaike Sohne, MD^22*, Paula F Ypma, MD, PhD^23*, Inger S. Nijhof, MD, PhD^24*, Saskia K. Klein, MD, PhD^25,26, Mark-David Levin, MD, PhD²⁷ and Sonja Zweegman²⁸

¹Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, NLD
²Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands
³HOVON data center, Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
⁴Department of Internal Medicine, Flevoziekenhuis, Almere, Netherlands
⁵Zuyderland Medical Center, Sittard-Geleen, NLD
⁶Maasstad Ziekenhuis, Rotterdam, Netherlands
⁷Department of Internal Medicine, Diakonessenziekenhuis, Utrecht, NLD
⁸Northwest Clinics, Alkmaar, NLD
⁹Department of Hematology, Ziekenhuis Netwerk Antwerpen, Antwerp, Belgium
¹⁰Department of Hematologie, Bernhoven Hospital, Uden, NLD
¹¹Jeroen Bosch Hospital, Den Bosch, NLD
¹²Department of Internal Medicine, Gelderse Vallei Hospital, Ede, Netherlands
¹³Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Bruxelles, Belgium
¹⁴Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands
¹⁵Amstelland Hospital, Amstelveen, NLD
¹⁶Erasmus MC University and Medical Center, Rotterdam, Netherlands
¹⁷Department of Hematology, Amsterdam UMC, Amsterdam, Netherlands
¹⁸Ikazia Hospital, Rotterdam, Netherlands
¹⁹Maxima Medical Center, Veldhoven, NLD
²⁰Department of Internal Medicine, Rijnstate Hospital, Arnhem, Netherlands
²¹Oncologisch Centrum Leeuwarden, Medisch Centrum Leeuwarden, Leeuwarden, Netherlands
²²Department of Internal Medicine/Hematology, Antonius Ziekenhuis, Nieuwegein, NLD
²³Haga Hospital, The Hague, Netherlands
²⁴Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands
²⁵Meander Medical Center, Amersfoort, Netherlands
²⁶University Medical Center Groningen, Groningen, Netherlands
²⁷Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
²⁸VUMC, Amsterdam, Netherlands

Gordon Cook, MD^1,2*, Charlotte Pawlyn, BA, MB BChir, PhD, MRCP, FRCPath^3,4, Kara-Louise Royle, MSc^2*, Amy Beth Coulson, MSc^2*, Jennifer Bird, MBBS, MRCP^5*, Stella Bowcock, MD, BA, FRCP, FRCPath, MA^6,7*, Matthew W Jenner^8*, Bhuvan Kishore, MD^9*, Christopher Parrish, MD¹⁰, Neil K Rabin, MD, PhD^11*, Phillip Best^2*, Sharon Gillson^2*, Rowena Henderson^2*, Catherine Olivier^2*, Martin F. Kaiser, MD, FRCP, FRCPath³, Ruth M. de Tute, PhD, FRCPath^12*, Roger G Owen, MD^12*, Mark T Drayson, MD^13*, John R Jones, MD^7,14,15*, Bryony Dawkins, BA, MSc^16*, David Meads, Ba, MSc, PhD^16*, David Cairns, PhD^2* and Graham Jackson, MBBS, FRCP, FRCPath, MA, DM¹⁷

¹Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
³The Institute of Cancer Research, London, United Kingdom
⁴The Royal Marsden NHS Foundation Trust, London, United Kingdom
⁵Department of Haematology, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom
⁶Queen Mary's Sidcup NHS Trust, Sidcup, United Kingdom
⁷King's College Hospital NHS Foundation Trust, London, United Kingdom
⁸Department of Haematology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
⁹University Hospitals Birmingham NHS Foundation Trust, WMRC, Birmingham, United Kingdom
¹⁰Leeds Teaching Hospitals NHS Trust, Leeds, ENG, United Kingdom
¹¹Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
¹²HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
¹³Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
¹⁴Eastbourne District General Hospital, Eastbourne, United Kingdom
¹⁵Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom
¹⁶Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom
¹⁷Department of Haematology, University of Newcastle, Newcastle upon Tyne, United Kingdom

Magaret Macro^1*, Cyrille Touzeau, MD, PhD^2*, Clara Mariette, MD^3*, Salomon Manier, MD, PhD^4,5, Sabine Brechignac, MD^6*, Laure Vincent, MD^7*, Benjamin Hebraud, MD^8*, Olivier Decaux, MD, PhD^9*, Samantha Schulmann, MD^10*, Caroline Bureau Lenoir, MD^11*, Pascal Godmer, MD^12*, Jean-Jacques Parienti, MD, PHD^13* and Xavier Leleu, MD¹⁴

¹Institut d’Hématologie de Basse Normandie, Centre Hospitalier et Universitaire de Caen, Caen, France
²Hématologie Clinique CHU Hôtel Dieu, University Hospital, Nantes, France
³Service d'Hématologie, CHU de Grenoble, Grenoble, France
⁴University of Lille, INSERM UMRS1277, CNRS UMR9020, Lille, MA, France
⁵Service des Maladies du Sang, CHU Lille, Lille, France
⁶Hematology, Avicenne Hospital, APHP, University Paris XIII, Bobigny, France
⁷CHU de Montpellier / Département d'hématologie clinique, Hôpital Saint-Eloi, Montpellier, France
⁸Institut Universitaire du Cancer and University Hospital, Toulouse, France
⁹Service d'Hématologie, CHU de Rennes, Rennes, France
¹⁰Service d'Hématologie, CHRU Nancy, University Hospital, Nancy, France
¹¹Polyclinique Bordeaux Nord Aquitaine, Bordeaux, France
¹²Clinical Hematology, Centre Hospitalier Bretagne Atlantique, Vannes, France
¹³Unité de recherche clinique, Hospital University Caen, Caen, France
¹⁴Service D'Hématologie Et Thérapie Cellulaire, Poitiers, France

Shaji K Kumar, MD¹, Simon J Harrison, MD², Michele Cavo, MD, PhD^3*, Javier de la Rubia, MD, PhD^4*, Rakesh Popat, MBBS, FRCPath, PhD^5*, Cristina J. Gasparetto, MD^6*, Vania Hungria⁷, Hans Salwender, MD^8*, Kenshi Suzuki, MD, PhD⁹, Inho Kim, MD, PhD^10*, Maika Onishi, MD, MAS¹¹, Grace Ku, MD^11*, Rajvineeth Kumar Pothacamury, MD^12*, Vasudha Sehgal, PhD^12*, Abdullah A. Masud, PhD^12*, Jeremy A. Ross, PhD^12*, Edyta Dobkowska, MD^13* and Philippe Moreau, MD, PhD^14*

¹Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
²Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, VIC, Australia
³IRCCS Azienda Ospedaliero Universitaria di Bologna, Seragnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy
⁴Hematology Service Hospital La Fe and School of Medicine and Dentistry, Catholic University of Valencia, Valencia, Spain
⁵University College London Hospitals, NHS Foundation Trust, London, United Kingdom
⁶Duke University Medical Center, Durham, NC
⁷Clinica São Germano, São Paulo, Brazil
⁸Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
⁹Department of Hematology, Japanese Red Cross Central Medical Center, Tokyo, Japan
¹⁰Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South)
¹¹Genentech, Inc., South San Francisco, CA
¹²AbbVie Inc., North Chicago, IL
¹³Pharmacyclics Switzerland GmbH, An AbbVie Company, Schaffhausen, Switzerland
¹⁴University Hospital Hôtel-Dieu, Nantes, Nantes, France

Herve Avet Loiseau, MD, PhD¹, Pieter Sonneveld², Philippe Moreau, MD, PhD^3*, Fritz Offner, MD, PhD⁴, Vincent H.J. van der Velden, PhD^5*, Denis Caillot, MD^6*, Cyrille Hulin^7*, Bertrand Arnulf, MD^8*, Jill Corre^1*, Mohamad Mohty, MD, PhD⁹, Lionel Karlin^10*, Jérôme Lambert, MD, PhD^11*, Margaret Macro^12*, Aurore Perrot^13*, Mark-David Levin, MD, PhD¹⁴, Saskia K. Klein, MD, PhD^15*, Anne-Marie Stoppa^16*, Michel Delforge^17*, Sonja Zweegman¹⁸, Kon-Siong Jie, MD¹⁹, Niels W.C.J. Van De Donk²⁰, Maria Krevvata, PhD^21*, Fabio Rigat^22*, Shiyi Yang^21*, Veronique Vanquickelberghe^23*, Carla de Boer^24*, Tobias Kampfenkel²⁴, Jessica Vermeulen²⁴, Soraya Wuillème, PharmD, PhD^25*, Annemiek Broyl^26* and Marie C Bene, PharmD, DPhil^25*

¹Unite de Genomique du Myelome, IUC-Oncopole, Toulouse, France
²Erasmus University Medical Center Cancer Institute, Rotterdam, Netherlands
³Hematology, University Hospital Hôtel-Dieu, Nantes, France
⁴Hematology, University Hospital Ghent, Gent, Belgium
⁵Department of Immunology, Erasmus MC, Rotterdam, Netherlands
⁶CHU Dijon, Hôpital Du Bocage, Dijon, France
⁷Department of Hematology, Hôpital Haut Lévêque, University Hospital, Pessac, France
⁸Immuno-Hématologie, Hopital Saint Louis, APHP, Paris, France
⁹Hospital Saint-Antoine, Sorbonne University, Paris, France
¹⁰Department of Hematology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France
¹¹Biostatistical Department, Hôpital Saint Louis, Paris, France
¹²Centre Hospitalier Universitaire (CHU) de Caen, Caen, France
¹³CHU de Toulouse, IUCT-O, Université de Toulouse, UPS, Service d’Hématologie, Toulouse, France
¹⁴Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
¹⁵Department of Hematology, University Medical Center Groningen, Groningen, Netherlands
¹⁶Institut Paoli Calmettes, Marseille, France
¹⁷Universitaire Ziekenhuizen Leuven, Leuven, Belgium
¹⁸Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Department of Hematology, Amsterdam, Netherlands
¹⁹Zuyderland MC, Sittard, Netherlands
²⁰Department of Hematology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²¹Janssen Research & Development, LLC, Spring House, PA
²²Janssen-Cilag Limited, High Wycombe, United Kingdom
²³Janssen Research & Development, LLC, Beerse, Belgium
²⁴Janssen Research & Development, LLC, Leiden, Netherlands
²⁵Hematology Biology, University Hospital Hôtel Dieu, Nantes, France
²⁶Erasmus MC Cancer Institute, Rotterdam, Netherlands