Marietta Truger^1*, Stephan Hutter, PhD^1*, Manja Meggendorfer, PhD¹, K. Martin Kortuem, MD^2*, Niroshan Nadarajah^1*, Wencke Walter, PhD^1*, Constance Baer, PhD¹, Leo Rasche, MD^2*, Wolfgang Kern, MD¹, Torsten Haferlach, MD¹, Hermann Einsele³ and Claudia Haferlach, MD¹

¹MLL Munich Leukemia Laboratory, Munich, Germany
²Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany
³Department of Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany

Rie Nakamoto-Matsubara, MD, PhD^1,2*, Valentina Nardi, MD^1,3, Cristina Panaroni, PhD^1,4, Keertik Fulzele, PhD^1,2*, Tomoaki Mori, MD, PhD^1,2*, Rakesh Verma, PhD^1,2*, Andrew J. Yee, MD^1,2, Andrew R. Branagan, MD, PhD^1,2, Elizabeth O’Donnell, MD^1,2* and Noopur S. Raje, MD^1,2

¹Harvard Medical School, Boston, MA
²Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA
³Department of Pathology, Massachusetts General Hospital, Boston, MA
⁴Center for Multiple Myeloma, Massachusetts General Hospital - Cancer Center, Boston, MA

Santiago Thibaud, MD¹, Aaron Etra, MD², Ryan Subaran, PhD^3*, Zachry Soens, MS^3*, Scott Newman, PhD^3*, Rong Chen, PhD^3*, Ajai Chari, MD⁴, Hearn Jay Cho, MD, PhD^5,6, Sundar Jagannath⁴, Deepu Madduri, MD⁴, David T. Melnekoff, MS^7*, Shambavi Richard^6*, Joshua Richter, MD⁶, Larysa Sanchez, MD⁴, Kuan-lin Huang, PhD^8*, Alessandro Lagana, PhD^7*, Samir Parekh, MD⁶ and Kenan Onel, MD, PhD⁸

¹Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
²Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY
³Sema4, Stamford, CT
⁴Department of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁵Multiple Myeloma Research Foundation (MMRF), Norwalk, CT
⁶Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
⁸Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY

Nathanael R Fillmore, PhD^1,2,3*, Jennifer La, PhD^3*, Julie Tsu-Yu Wu, MD, PhD^4,5*, Westyn Branch-Elliman, MD^2,3*, Linden Huhmann, PhD^3*, Summer S Han, PhD^4*, Giovanni Parmigiani, PhD^1,6*, David P Tuck, MD^3,7*, Mary Brophy, MD, MPH^3,7*, Nhan V Do, MD^3,7*, Albert Y Lin, MD^4,5* and Nikhil C. Munshi, MD, PhD^1,2,3

¹Dana-Farber Cancer Institute, Boston, MA
²Harvard Medical School, Boston, MA
³VA Boston Healthcare System, Boston, MA
⁴Stanford University, Palo Alto, CA
⁵VA Palo Alto Healthcare System, Palo Alto, CA
⁶Harvard T.H. Chan School of Public Health, Boston, MA
⁷Boston University School of Medicine, Boston, MA

William Pilcher, BSc^1*, Beena E Thomas, Ph.D^2,3*, Swati S Bhasin, PhD^2,4, Reyka G Jayasinghe, PhD^5,6*, Adeeb H Rahman, PhD^7,8*, Seunghee Kim-Schulze, PhD^9*, Edgar Gonzalez-Kozlova, PhD^10*, Taxiarchis Kourelis, MD¹¹, Madhav V Dhodapkar, MD¹², Ravi Vij, MBBS^13,14, Shaji K Kumar, MD^11,15, Shaadi Mehr, PhD^16*, Mark Hamilton, PhD^17*, Hearn Jay Cho, MD, PhD^18,19, Daniel Auclair, PhD¹⁹, David Avigan, MD²⁰, Sacha Gnjatic, PhD^7,21*, Li Ding, PhD^22* and Manoj Bhasin, PhD⁴

¹Emory University, Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA
²Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA
³Emory School of Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
⁴Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
⁵McDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO
⁶Department of Medicine, Washington University School of Medicine, Saint Louis, MO
⁷Mount Sinai School of Medicine, New York, NY
⁸Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY
⁹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
¹⁰Department of Genetics and Genomics., Icahn School of Medicine at Mount Sinai, New York
¹¹Division of Hematology, Mayo Clinic, Rochester, MN
¹²Winship Cancer Institute, Emory University, Atlanta, GA
¹³Washington University School of Medicine, Ballwin, MO
¹⁴Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO
¹⁵Mayo Clinic, Rochester, MN
¹⁶Multiple Myeloma Research Foundation, Norwalk, CT
¹⁷The Multiple Myeloma Research Foundation (MMRF), Norwalk, CT
¹⁸Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
¹⁹Multiple Myeloma Research Foundation (MMRF), Norwalk, CT
²⁰Beth Israel Deaconess Medical Center, Boston, MA
²¹Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²²Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO

Nancy Gillis, PharmD, PhD^1,2, Lauren C Peres, PhD, MPH^3*, Christelle M Colin-Leitzinger, PhD^3*, Mingxiang Teng, PhD^4*, Raghunandan Reddy Alugubelli, MS^5*, Gabriel De Avila, BS^6*, Dongliang Du, PhD^4*, Erin M Siegel, PhD, MPH^3,6*, Jamie Teer, PhD^4*, Oliver Hampton, PhD^7*, Melissa Alsina, MD⁸, Jason Brayer, PhD, MD², Brandon J. Blue, MD², Ariosto Siqueira Silva, PhD^9*, Rachid Baz, MD^2*, Taiga Nishihori, MD¹⁰ and Kenneth H. Shain, MD, PhD²

¹Department of Cancer Epidemiology, Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL
⁴Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL
⁵Collaborative Data Services Core, Moffitt Cancer Center, Tampa, FL
⁶Total Cancer Care Department, Moffitt Cancer Center, Tampa, FL
⁷Bioinformatics an Biostatistics Department, M2GEN, Tampa, FL
⁸Department of Blood & Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
⁹Department of Cancer Physiology, Moffitt Cancer Center, Tampa, FL
¹⁰Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL