Banu Aygun, MD^1,2, George A. Tomlinson, PhD, BSc, MSc^3*, Patrick T. McGann, MD^4,5, Leon Tshilolo, MD PhD^6*, Thomas N. Williams, MD PhD^7*, Peter Olupot-Olupot, MD PhD^8*, Brigida Santos, MD^9*, Susan E. Stuber, MA^10*, Adam Lane, PhD^11*, Teresa Latham, MA^10* and Russell E. Ware, MD, PhD^5,12

¹Pediatric Hematology Oncology and Stem Cell Transplantation, Cohen Children's Medical Center, New Hyde Park, NY
²Cohen Children's Medical Center of New York, New Hyde Park, NY
³Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
⁴Cincinnati Children's Hospital Medical Center, Division of Hematology, Cincinnati, OH
⁵Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁶Centre Hospitalier Monkole, Kinshasa, Congo (The Democratic Republic of the)
⁷KEMRI-Wellcome Trust Programme, Kilifi, Kenya
⁸Mbale Clinical Research Institute, Mbale, Uganda
⁹Hospital Pediatrico David Bernardino, Luanda, Angola
¹⁰Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹¹Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹²Cincinnati Children's Hospital Medical Center, Children's Hospital Medical Center, Cincinnati, OH

Brigida Santos, MD^1*, Maria Nakafeero^2*, Adam Lane, PhD^3*, Leon Tshilolo, MD PhD^4*, Thomas N. Williams, MD PhD^5*, Peter Olupot-Olupot, MD PhD^6*, Janet Adams^7*, Banu Aygun, MD⁸, Susan E. Stuber, MA^9*, George A. Tomlinson, PhD, BSc, MSc^10*, Teresa Latham, MA^9*, Patrick T. McGann, MD^7,11 and Russell E. Ware, MD, PhD^11,12

¹Hospital Pediatrico David Bernardino, Luanda, Angola
²Global Health Uganda, Kampala, UGA
³Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Centre Hospitalier Monkole, Kinshasa, Congo (The Democratic Republic of the)
⁵KEMRI-Wellcome Trust Programme, Kilifi, Kenya
⁶Mbale Clinical Research Institute, Mbale, Uganda
⁷Cincinnati Children's Hospital Medical Center, Division of Hematology, Cincinnati, OH
⁸Pediatric Hematology Oncology and Stem Cell Transplantation, Cohen Children's Medical Center, New Hyde Park, NY
⁹Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁰Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
¹¹Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹²Cincinnati Children's Hospital Medical Center, Children's Hospital Medical Center, Cincinnati, OH

Renee Cheng, MD¹, Andrew Srisuwananukorn, MD^2*, Jin Han^3*, Michel Gowhari, DO⁴, Franklin Njoku, MD^5*, Faiz Ahmed Hussain, MD^6*, Robert E. Molokie, MD^7,8, Victor R. Gordeuk, MD⁵ and Santosh L. Saraf, MD^5,9

¹Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL
²Mount Sinai Health System, New York, NY
³Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, IL
⁴Division of Hematology/Oncology, University of Illinois at Chicago College of Medicine, Chicago, IL
⁵Department of Medicine, University of Illinois at Chicago, Chicago, IL
⁶Division of Hematology/Oncology, University of Illinois College of Medicine, Chicago, IL
⁷Jesse Brown VA Medical Center, Chicago, IL
⁸Department of Medicine, Division of Hematology and Oncology, University of Illinois at Chicago, Chicago, IL
⁹Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, Chicago, IL

Kenneth W. Wood, PhD^1*, James Geib, BS^1*, Eric Wu, PhD^1*, Jason Berlin, MS^1*, Irena Webster, MPH, MA^1*, Kenneth I. Ataga, MD², Jo Howard, MBBChir, MRCP, FRCPath³, Jeremie H. Estepp, MD⁴, Marilyn J. Telen, MD⁵ and Julie Brevard, MPH^1*

¹Forma Therapeutics, Inc., Watertown, MA
²University of Tennessee Health Science Center at Memphis, Memphis, TN
³Guy's and St. Thomas' Hospital, London, United Kingdom
⁴Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
⁵Duke Univ. Med. Ctr., Durham, NC

Emmanuela E. Ambrose, MD^1,2, Luke R. Smart, MD^3,4,5, Primrose Songoro, RN^6*, Idd Shabani, MD^7,8*, Protas Komba, MD^1*, Mwesige Charles, BScHLS^9*, Thad A. Howard, MS^4*, Susan E. Stuber, MA^4*, Adam Lane, PhD^10*, Teresa Latham, MA^4*, Abel Nkono Makubi, PhD, MD, MSc^11* and Russell E. Ware, MD, PhD^3,4

¹Department of Paediatrics and Child Health, Bugando Medical Centre, Mwanza, Tanzania, United Republic of
²Department of Paediatrics and Child Health, Catholic University of Health & Allied Sciences, Mwanza, Tanzania, United Republic of
³Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁵Division of Hematology/Oncology, University of Cincinnati, Cincinnati, OH
⁶Department of Paediatrics, Bugando Medical Centre, Mwanza, Tanzania, United Republic of
⁷Department of Pathology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania, United Republic of
⁸Department of Pathology, Bugando Medical Centre, Mwanza, Tanzania, United Republic of
⁹Department of Laboratory Services, Bugando Medical Centre, Mwanza, Tanzania, United Republic of
¹⁰Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹¹Bugando Medical Centre, Mwanza, Tanzania, United Republic of

Najibah Aliyu Galadanci, MBBS, MPH¹, Maira Sohail, MPH^2*, Oluwasegun Philip Akinyelure, MBBS, MPH^2*, Akinyemi I. Ojesina, MBBS, PhD^2* and Julie Kanter, MD^3,4

¹School of Public Health/Epidemiology, University of Alabama at Birmingham, Birmingham, AL
²School of Public health/Epidemiology, University of Alabama at Birmingham, Birmingham, AL
³Hematology/Oncology, Comprehensive Sickle Cell Center, University of Alabama at Birmingham, Birmingham, AL
⁴Division of Hematology-Oncology, University of Alabama-Birmingham, Birmingham, AL

Olubusola Oluwole, MD, MS¹, Amma owusu-Ansah, MD, MSc^2*, Seyed Mehdi Nouraie, MD, PhD^3* and Enrico M Novelli, M.D., M.S.⁴

¹University of Washingon, Seattle, WA
²Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
³Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA
⁴Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA

Matthew M. Heeney, MD¹, David C. Rees, MD^2*, Mariane de Montalembert, MD, PhD^3*, Isaac Odame, MD^4,5, R. Clark Brown, MD, PhD⁶, Yasser Wali, MD^7*, Thu Thuy Nguyen^8*, Du Lam, MD^9*, Raquel Merino Herranz^10* and Julie Kanter, MD¹¹

¹Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston
²Department of Paediatric Haematology, King's College Hospital, London, United Kingdom
³Hôpital Universitaire Necker-Enfants Malades, Paris, France
⁴The Hospital for Sick Children (SickKids), Toronto, Canada
⁵University of Toronto, Toronto, Canada
⁶Children's Healthcare of Atlanta, Atlanta, GA
⁷Sultan Qaboos University Hospital, Muscat, Na, Oman
⁸Novartis Pharma S.A.S., Rueil-Malmaison, France
⁹Novartis Pharmaceuticals Co., East Hanover, NJ
¹⁰Novartis Pharmaceuticals Co., Basel, Switzerland
¹¹Division of Hematology-Oncology, University of Alabama-Birmingham, Birmingham, AL

Ahmar Urooj Zaidi, MD¹, Thokozeni Lipato, MD^2*, Ofelia A. Alvarez, MD³, Alexander Lonshteyn, PhD^4*, Derek Weycker, PhD^4*, Nhat Pham^4*, Thomas E Delea, MSIA^4*, Irene Agodoa, MD^5*, Ze Cong, PhD^5* and Nirmish Shah, MD⁶

¹Wayne State University/Children's Hospital of Michigan/Detroit Medical Center, Detroit Medical Center, Detroit, MI
²Virginia Commonwealth University, Richmond, VA
³Univ. of Miami School of Med., Miami, FL
⁴Policy Analysis Inc. (PAI), Brookline, MA
⁵Global Blood Therapeutics, South San Francisco, CA
⁶Division of Hematology, Duke University School of Medicine, Durham, NC

Charity I Oyedeji, MD^1,2, Carl Pieper, PhD^2,3*, Katherine Hall, PhD^2,4,5*, Miriam Morey, PhD^2,4,5*, Heather Whitson, MD, MHS^2,4* and John J. Strouse, MD, PhD^1,6

¹Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC
²Claude D. Pepper Older Americans Independence Center, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC
³Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC
⁴Department of Medicine, Division of Geriatrics, Duke University Medical Center, Durham, NC
⁵Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Durham, NC
⁶Pediatric Hematology/Oncology, Duke University School of Medicine, Durham, NC

Prasanth Lingamaneni^1*, Krishna Moturi, MD^2*, Sheeba Ba Aqeel, MD^3*, Shristi Upadhyay Banskota, MD^1*, Binav Baral, MD^1* and Maryam Zia⁴

¹John H Stroger Hospital of Cook County, Chicago, IL
²John H. Stroger Hospital of Cook County, chicago, IL
³John Stroger Hospital of Cook County, Chicago, IL
⁴Division of Hematology/Oncology, John H Stroger Jr. Hospital of Cook County, Chicago, IL

Kenneth I. Ataga, MD¹, Santosh L. Saraf, MD², Vimal K. Derebail, MD^3*, Claire C. Sharpe^4*, Adlette Inati, MD, FAAP⁵, Jeffrey D. Lebensburger, DO⁶, Laurie DeBonnett, MD^7*, Yifan Zhang, PhD^7* and Pablo Bartolucci, MD, PhD^8*

¹UTHSC Center for Sickle Cell Disease, Memphis, TN
²Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, Chicago, IL
³University of North Carolina Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
⁴Renal Sciences, Department of Inflammation Biology, King’s College London, London, United Kingdom
⁵Lebanese American University, School of Medicine, Beirut and Division of Pediatric Hematology and Oncology, Nini Hospital, Tripoli, Lebanon
⁶Division of Pediatric Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL
⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁸Service de Médecine Interne, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris 12, Créteil, France

Jennifer G. Davila, MD¹, Sarah H. O'Brien, MD² and Joseph R Stanek, MS^3*

¹The Children's Hospital At Montefiore-Aecom, Bronx, NY
²Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, Nationwide Children's Hospital, Columbus, OH
³Division of Biostatistics, Nationwide Children's Hospital, Columbus, OH

Sharmila Raghunandan, DO, MPH^1*, Derrick L Goubeaux, DO², Christine R Hollenkamp, APRN^3*, Rae M Blaylark, CHW^3* and Stephen C Nelson, MD^4*

¹Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA
²Cancer and Blood Disorders Program, Children's Minnesota, Minneapolis, MN
³Children's Minnesota, Minneapolis, MN
⁴Children's Hospitals and Clinics of Minnesota, Minneapolis, MN

Yagahira E. Castro-Sesquen, Ph.D.^1*, Santosh L. Saraf, MD², Victor R. Gordeuk, MD³, Sergei Nekhai, PhD⁴ and Marina Jerebtsova, PhD⁵

¹Department of Microbiology, Howard University, Washington DC, DC
²Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, Chicago, IL
³Department of Medicine, University of Illinois at Chicago, Chicago, IL
⁴Center for Sickle Cell Disease and Department of Medicine, Howard University, Washington, DC
⁵Department of Microbiology, Howard University, Washington, DC

Vignesh Chidambaram^1*, Jennifer Jones, MD², Parvez Lokhandwala, MD^3*, Sophie M. Lanzkron, MD, MHS², Rosalyn Stewart, MBA., MD, MS^4* and Lydia H. Pecker, MD²

¹Johns Hopkins Bloomberg School of Public Health, LITTLE ROCK, AR
²Department of Medicine, Division of Hematology, Johns Hopkins Medicine, Baltimore, MD
³Department of Transfusion Medicine, Johns Hopkins University, Baltimore, MD
⁴Division of General Internal Medicine, Department of Medicine, Johns Hopkins Medicine, Baltimore, MD

Sarah Sewaralthahab, MBBS, MPH and Hedy Smith, MD, PhD

Medstar Washington Hospital Center, Washington, DC

Nirmish Shah, MD¹, Ahmar Urooj Zaidi, MD², Michael U. Callaghan, MD³, Darla Liles, MD⁴, Clarissa E. Johnson, MD^5* and Laura M De Castro, MD, MHSc⁶

¹Duke University Health System, Durham, NC
²Wayne State University/Children's Hospital of Michigan/Detroit Medical Center, Detroit Medical Center, Detroit, MI
³Department of Pediatrics, Central Michigan University, Detroit, MI
⁴Division of Hematology–Oncology, Vidant Medical Center/East Carolina University, Greenville, NC
⁵Cook Children's Medical Center, Fort Worth, TX
⁶Comprehensive Sickle Cell Center, University of Pittsburgh Medical Center, Pittsburgh, PA

Avani Singh, MD¹, Conner Olsen, MD^1*, Xu Zhang, PhD^2* and Robert E. Molokie, MD^3,4

¹Department of Internal Medicine, University of Illinois at Chicago, Chicago, IL
²Department of Medicine, University of Illinois at Chicago, Chicago, IL
³Jesse Brown VA Medical Center, Chicago, IL
⁴Department of Medicine, Division of Hematology and Oncology, University of Illinois at Chicago, Chicago, IL

Victor R. Gordeuk, MD¹, Barbara Kroner, PhD^2*, Norma Pugh, PhD^2*, Jane S. Hankins, MD, MS³, Abdullah Kutlar, MD⁴, Allison A. King, MD, MPH, PhD⁵, Nirmish Shah, MD⁶, Julie Kanter, MD⁷, Jeffrey Glassberg, MD^8* and Marsha Treadwell, PhD^9*

¹Department of Medicine, University of Illinois at Chicago, Chicago, IL
²RTI International, Research Triangle Park, NC
³Associate Member, Director of the Sickle Cell Program, St. Jude Children's Research Hospital, Memphis, TN
⁴Center for Blood Disorders, Augusta University, Augusta, GA
⁵Washington University in St. Louis, Clayton, MO
⁶Division of Hematology, Duke University School of Medicine, Durham, NC
⁷Director, Adult Sickle Cell Program, Comprehensive Sickle Cell Center,, Birmingham, AL
⁸Icahn School of Medicine at Mount Sinai, New York City, NY
⁹Children's Hospital and Research Center, Oakland, Oakland, CA