-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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711. Cell Collection and Processing: Poster II

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
AML, apheresis, Biological, HSCs, multiple myeloma, bone marrow, CML, Diseases, Bone Marrow Failure, CMML, Therapies, MDS, Biological Processes, MPN, cell expansion, gene therapy, Technology and Procedures, Cell Lineage, Plasma Cell Disorders, Lymphoid Malignancies, Clinically relevant, Myeloid Malignancies, transplantation, stem cells
Sunday, December 6, 2020: 7:00 AM-3:30 PM
2358
Orvacabtagene Autoleucel (orva-cel; JCARH125): A Fully Human BCMA-Targeted Second-Generation CAR T Cell Product Characterized By a Predominant Central Memory Phenotype with High in Vitro and In Vivo Proliferative Potential and Sustained In Vivo Persistence

Lucrezia Colonna, PhD1*, Garnet Navarro, BS1*, Todd Devries, PhD1*, Valeria Beckett, MS1*, Anthony Amsberry, BS1*, Aditya Radhakrishnan, PhD1*, Julia Piasecki, BA1*, Mark Heipel, BS1*, Yan Li, PhD1*, Uma Kavita, PhD2*, Melissa G Works, PhD1* and Mirna Mujacic, PhD1*

1Juno Therapeutics, a Bristol-Myers Squibb Company, Seattle, WA
2Bristol-Myers Squibb Company, Princeton, NJ
2359
Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

Giulia Barbarito1*, Beruch Dejene, BS1*, David C Shyr, MD1*, Gopin Saini, MBBS1*, Linda Oppizzi, BS1*, Sruthi Mantri1*, Hye-Sook Kwon, PhD2*, Matthew H. Porteus, MD, PhD3, Kenneth I. Weinberg, MD4 and Alice Bertaina, MD, PhD1

1Department of Pediatrics/Division of Stem Cell Transplantation and Regenerative Medicine, Stanford School of Medicine, Palo Alto, CA
2Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University Medical Center, Stanford, CA
3Department of Pediatrics, Stanford School of Medicine, Stanford, CA
4Department of Pediatrics/Division of Stem Cell Transplantation and Regenerative Medicine, Stanford School of Medicine, palo Alto, CA
2360
On-Demand Plerixafor with Cyclophosphamide and G-CSF for Hematopoietic Stem-Cell Mobilization in Multiple Myeloma Patients: Preliminary Results of a Prospective Observational Study (MOZOBL06877)

Roberto Mina, MD*, Francesca Bonello*, Giuseppe Milone, Maria Teresa Petrucci, Chiara Nozzoli*, Velia Bongarzoni*, Andrea Capra*, Francesco Pisani*, Giusy Cetani*, Alessandra Malfitano*, Delia Rota Scalabrini*, Stelvio Ballanti*, Roberto M. Lemoli, Patrizia Tosi*, Daniele Derudas*, Tommaso Caravita di Toritto*, Massimo Offidani, Pellegrino Musto, Paolo Corradini, Michele Cavo*, Mario Boccadoro and Alessandra Larocca

GIMEMA, European Myeloma Network, Italy
2361
Accessible Source of Stem Cells: Expansion of CD34+ Cells in Bulk Peripheral Blood Mononuclear Cells Using UM171

Muhammad Elnaggar, MD, PhD1*, Igor Pavlovski2*, Anjud Al-Mohannadi2*, Chiara Cugno, MD2, Jean-Charles Grivel3* and Sara Deola, MD, PhD2

1Research, Sidra Medicine, Doha, Qatar
2Sidra Medicine, Doha, Qatar
3Research, Sidra Medicine, Doha, MD, Qatar
2362
Timing of Daratumumab Administered Pre-Mobilization in Multiple Myeloma Impacts Pre-Harvest Peripheral Blood CD34+ Cell Counts and Plerixafor Use

Danny Luan, MPH1, Paul J Christos, Dr.P.H., M.S.2*, Michael Ancharski, MLS(ASCP)3*, Danielle Guarneri, BS, CCRP4*, Roger Pearse, MD, PhD4, Adriana C Rossi, MD, MSc4*, Tsiporah B. Shore, MD4, Sebastian Mayer, MD4*, Adrienne A. Phillips, MD4, Jingmei Hsu, MD4, Ljiljana V. Vasovic, MD5*, Yen-Michael S. Hsu, MD, PhD5, Koen van Besien, MD, PhD4, Ruben Niesvizky, MD4 and Cara A. Rosenbaum, MD4*

1Weill Cornell Medical College, New York, NY
2Department of Healthcare Policy & Research, Weill Cornell Medicine, New York, NY
3Cellular Therapy Laboratory, NewYork-Presbyterian Hospital/Weill Cornell Medical College, New York, NY
4Division of Hematology and Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
5Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
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*signifies non-member of ASH