62nd ASH Annual Meeting and Exposition: 711. Cell Collection and Processing: Poster I

Oral and Poster Abstracts
Poster

Adult, AML, apheresis, Biological, HSCs, multiple myeloma, Diseases, CAR-Ts, thalassemia, Therapies, Pediatric, Hemoglobinopathies, cell expansion, Technology and Procedures, Cell Lineage, immunotherapy, Plasma Cell Disorders, Lymphoid Malignancies, Study Population, Clinically relevant, Myeloid Malignancies, NK cells

1451

Factors Affecting Lymphocyte Collection Efficiency and Manufactured Product Specification during Leukapheresis for Diffuse Large B Cell Lymphoma Patients Treated with Commercial Tisagenlecleucel

Ariel Perez Perez, MD¹, Christina A Bachmeier, PharmD²^*, Renee Smilee¹^*, Albert J Ribickas³^*, Aleksandr Lazaryan, MD, PhD, MPH⁴, Julio C. Chavez, MD⁵, Claudio Anasetti, MD⁶, Bijal Shah, MD¹, Farhad Khimani, MBBS⁷, Taiga Nishihori, MD², Marco L. Davila, MD, PhD⁸, Frederick L. Locke, MD², Michael D. Jain, MD, PhD² and Hien D. Liu, MD⁶

¹Moffitt Cancer Center, Tampa, FL
²Department of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
³Moffitt Cancer Center, Tampa
⁴Hematology, Oncology and Transplantation, Moffitt Cancer Center, Tampa, FL
⁵Division of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Lutz, FL
⁶Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁷Department of Blood and Marrow Transplantation and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁸H. Lee Moffitt Cancer Center, Tampa, FL

1452

Cell Density of NK Cells during Ex Vivo Expansion Impacts NK Cell Surface TRAIL Expression

Joseph A. Clara, MD¹, Robert Reger, MS¹^*, Mala Chakraborty, PhD¹^*, Steven L Highfill, PhD²^*, Jianjian Jin, PhD²^*, David F. Stroncek, MD² and Richard W. Childs, MD¹^*

¹National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Center for Cellular Engineering, National Institutes of Health, Bethesda, MD

1453

PBSC Mobilization for Auto-HSCT in Myeloma: Growth Factors Vs Growth Factors + Chemotherapy

Jeremy L. Ramdial, MD¹, Junsheng Ma, MS²^*, Denai R. Milton, MS²^*, Ruby Delgado¹^*, Qaiser Bashir, MD³, Samer A. Srour, MD, MS³, Neeraj Saini, MD³, Yago Nieto, MD⁴, Chitra Hosing, MD¹, Uday R. Popat, MD³, Regan Murphy, PA-C¹^*, Hans C. Lee, MD⁵, Krina K. Patel, M.D.⁶, Elisabet E. Manasanch, MD⁵, Sheeba K. Thomas, MD⁵, Gregory P. Kaufman, MD⁵^*, Donna M. Weber, MD⁵, Robert Z. Orlowski, MD, PhD⁷, Richard E. Champlin, MD¹ and Muzaffar H. Qazilbash, MD¹

¹Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX
³Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Stem Cell Transplantation and Cellular Therapy, UT M.D. Anderson Cancer Ctr., Houston, TX
⁵Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX

1454

Mobilization of Auto-Stem Cells in the Thalassemia Major and Relationship with Iron Overload

Xiaoqin Feng¹^*, Yuelin He, MD¹^*, Bindanda Mvuama Van Timothee²^*, Jing Du²^*, Chunfu Li, MD³, Qiujun Liu⁴^*, Jianyun Wen⁴^*, Xuan Liu⁴^*, Rongfang Ding, MD⁵^*, Yongsheng Ruan, MD⁶^*, Xiaoting Liu⁴^* and Peifen Zhang²^*

¹Department of Pediatrics, Nanfang Hospital,Southern Medical University, Guangzhou, China
²Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Department of Pediatrics, Nanfang Hospital,Southern Medical University, Guangzhou, Guangdong, China
⁴Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China
⁵Pediatrics, Nanfang Hospital,Southern Medical University, Guangzhou, China
⁶Department of Pediatrics,Nanfang hospital,Southern Medical University, Los Angeles, CA

1455

Large Scale Ex Vivo Expansion of Γδ T Cells Using Artificial Antigen Presenting Cells for the Treatment of Acute Myeloid Leukemia

Justin C. Boucher, PhD¹, Bin Yu²^*, Gongbo Li, PhD, MBBS³^*, Bishwas Shrestha, PhD³, Jeffrey E. Lancet, MD⁴, David A. Sallman, MD⁵, Ana Marie Landin⁶^*, Adam William Mailloux, PhD⁶^*, Claudio Anasetti, MD⁷, Linda L. Kelley, PhD⁸, Marco L. Davila, MD, PhD³ and Nelli Bejanyan, MD⁹

¹Clinical Science Division, Moffitt Cancer Center, Tampa, FL
²Clinical Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
³Clinical Science Division, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁴Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁵Malignant Hematology Department, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁶Cell Therapy Facility, H. Lee Moffitt Cancer Center, Tampa, FL
⁷Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁸Cell Therapy Facility, Moffitt Cancer Center, Tampa, FL
⁹Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL

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^*signifies non-member of ASH

711.P1.15 711. Cell Collection and Processing: Poster I