Cem Akin, MD, PhD^1*, Hanneke Oude Elberink, MD, PhD^2*, Jason Gotlib, MD, MS³, Vito Sabato, MD, PhD^4*, Karin Hartmann, MD^5*, Sigurd Broesby-Olsen, MD^6*, Mariana Castells, MD, PhD^7*, Tsewang Tashi, MD^8*, Mark L. Heaney, MD⁹, Tracy I. George, MD¹⁰, Frank Siebenhaar, MD^11*, Deepti H. Radia, MRCPI, FRCPath^12*, Massimo Triggiani, MD, PhD^13*, Paul van Daele, MD^14*, Daniel J. DeAngelo, MD, PhD¹⁵, Oleg Schmidt-Kittler, PhD^16*, Hui-Min Lin, PhD^16*, Andrew Morrison, BS^16*, Brenton G. Mar, MD, PhD^16* and Marcus Maurer, MD^11*

¹University of Michigan, Ann Arbor, MI
²Department of Allergology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
³Division of Hematology, Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA
⁴Department of Immunology, Allergology and Rheumatology, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
⁵Division of Allergy, University of Basel, Basel, Switzerland
⁶Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark
⁷Brigham and Women’s Hospital, Boston, MA
⁸Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
⁹Columbia University Medical Center, New York, NY
¹⁰ARUP Laboratories, University of Utah, Salt Lake City, UT
¹¹Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, Dermatological Allergology, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany
¹²Department of Clinical Haematology, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom
¹³Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy
¹⁴Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands
¹⁵Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹⁶Blueprint Medicines Corporation, Cambridge, MA

Lin-Pierre Zhao, MD^1*, Rafael Daltro De Oliveira, MD^1*, Clemence Marcault^2*, Juliette Soret, MD^3*, Nicolas Gauthier, MD^4*, Emmanuelle Verger, PhD^5*, Nabih Maslah, PharmD^5,6*, Blandine Roux, MSc^7*, Nathalie Parquet, MD^8*, Christine Dosquet, MD^5*, Delphine Rea, MD, PhD⁸, Jean-Marc Zini, MD^9*, William Vainchenker^8*, Emmanuel Raffoux, MD^8*, Stephane Giraudier, MD, PhD^5,6*, Bruno Cassinat, PharmD, PhD^5,10*, Jean-Jacques Kiladjian, MD, PhD^11,12* and Lina Benajiba, MD, PhD^1,13*

¹Université de Paris, Clinical Investigations Center, Saint-Louis hospital, APHP, Paris, France
²Saint-Louis, Nice, France
³Centre d'Investigations Cliniques, Hôpital Saint-Louis; Assistance Publique – Hôpitaux de Paris; Université de Paris, Paris, France
⁴Centre d'Investigations Cliniques (INSERM CIC 1427), AP-HP, Hopital Saint-Louis, Université de Paris, Paris, FRA
⁵Université de Paris, Cellular biology Department, Saint-Louis hospital, APHP, Paris, France
⁶UMRS_1131, Inserm, Université de Paris, Institut de recherche Saint-Louis, Paris, France
⁷INSERM UMR 944, Saint-Louis Research Institute, Paris, France
⁸Université de Paris, Hematology department, Saint-Louis hospital, APHP, Paris, France
⁹Université de Paris, Hematology department, Saint-Louis hospital, APHP, Paris, FRA
¹⁰Institut de Recherche St Louis, Université de Paris, INSERM U1131, Paris, France
¹¹INSERM UMR 1131, Saint-Louis Research Institute, Paris, France
¹²Université de Paris, Clinical Investigations Center, Saint-Louis hospital, APHP, Paris, FRA
¹³APHP, INSERM U944, Institute of Hematology - St Louis Hospital, PARIS, France

Mark W. Drummond, PhD, FRCPath^1*, Charlotte Gaskell, BSc, MSc^2*, Claire Harrison, DM, FRCPath³, Adam J. Mead, MD, PhD⁴, Christina Yap, PhD, CStat^2,5*, Aimee E Jackson, BSc, MSc^2*, Jennifer Byrne, FRCP, FRCPath, PhD^6*, Fiona J Clark, FRCP, FRCPath^7*, Srinivasan Narayanan, FRCP, FRCPath^8*, David Bowen, MD⁹, Tim C.P Somervaille, PhD, FRCP, FRCPath^10,11, Emma Gudgin, MBBS, MRCP, FRCPath, PhD^12*, Dragana Milojkovic^13*, Rachel S Fletcher, PhD^2*, Charlotte K Brierley, MRCP, MD^14* and Steve Knapper, BMBCh, MRCP, FRCPath, DM¹⁵

¹Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom
²Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom
³Guy's and St Thomas' Hospital, London, United Kingdom
⁴MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⁵Clinical Trials and Statistics Unit, The Institute of Cancer Research, Surrey, United Kingdom
⁶Centre for Clinical Haematology, Nottingham University Hospitals Trust, Nottingham, ENG, United Kingdom
⁷Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
⁸Department of Haematology, University Hospital Southampton NHSFT, Southampton, United Kingdom
⁹St. James's Institute of Oncology, Leeds Teaching Hospitals, Leeds, United Kingdom
¹⁰The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
¹¹The Christie Hospital, Cancer Research UK Manchester Institute, Manchester, United Kingdom
¹²Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom
¹³Department of Haematology, Hammersmith Hospital, Imperial College NHS Trust, London, United Kingdom
¹⁴MRC Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
¹⁵Division of Cancer & Genetics, Cardiff University, Cardiff, United Kingdom

Claudia Lebedinsky, MD¹, Stephen P. Anthony, DO², Golam Mohi, PhD³, Huyuan Yang, PhD^1*, Jian Mei, PharmD^1* and Edgar Braendle, MD¹

¹Sumitomo Dainippon Pharma Oncology, Inc., Cambridge, MA
²Sumitomo Dainippon Pharma Oncology, Inc., Lehi, UT
³Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA

Paola Guglielmelli, MD¹, Jean-Jacques Kiladjian, MD, PhD^2*, Alessandro Vannucchi, MD¹, Ming-hui Duan, MD^3*, Haitao Meng, MD, PhD^4*, Ling Pan, MD, PhD^5*, Guangsheng He, MD, PhD^6*, Srdan Verstovsek, MD, PhD⁷, Françoise Boyer-Perrard, MD^8*, Fiorenza Barraco, MD^9*, Dietger Niederwieser, MD, PhD¹⁰, Ester Pungolino^11*, Anna Marina Liberati, MD¹², Claire Harrison, DM, FRCPath¹³, Pantelia Roussou, MSc^14*, Monika Wroclawska, MD^14*, Kevin Majidi^14*, Peter AW te Boekhorst, MD, PhD^15* and Heinz Gisslinger, MD^16*

¹CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera–Universitaria Careggi, University of Florence, Florence, Italy
²Hôpital Saint-Louis et Université Paris Diderot, Paris, France
³Peking Union Medical College Hospital, Beijing, China
⁴Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University; Institute of Hematology, Zhejiang University, Zhejiang, China
⁵West China Hospital of Sichuan University, Chengdu, China
⁶The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Jiangsu, China
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Centre Hospitalier Universitaire d’Angers, Angers, France
⁹Centre Hospitalier Universitaire Lyon Sud, Lyon, France
¹⁰Department of Hematology and Oncology, University Leipzig, Leipzig, Germany
¹¹Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
¹²Università degli Studi di Perugia, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy
¹³Department of Clinical Haematology, Guys and St Thomas NHS Trust, London, United Kingdom
¹⁴Novartis Pharma AG, Basel, Switzerland
¹⁵Department of Hematology, Erasmus Medical Center, Rotterdam, Netherlands
¹⁶Haematologie Haemostaseologie Innere Medizin I, AKH Allgemeines Krankenhaus Wien, Vienna, Austria

Daniel Rivera, MD^1*, Srdan Verstovsek, MD, PhD¹, Prithviraj Bose, MD¹, Naveen Pemmaraju, MD¹, Lingsha Zhou^1*, Sherry A. Pierce, BSN, BA^1*, Hagop M. Kantarjian, MD², Zeev E. Estrov, MD¹ and Lucia Masarova, MD^1*

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

John Mascarenhas, MD^1,2,3,4,5, Heidi E. Kosiorek, MS^6,7*, Lilian Varricchio, PhD^8*, Rupali Bhave, M.D.^9*, Andrew T. Kuykendall, MD^10,11,12,13, Rami Komrokji, MD¹⁴, Aaron T. Gerds, MD, MS^{15,16,17,18,19,20,21,22,23,24}, Jeanne M. Palmer, Md^25,26,27, Amelia R. Gabler^{1,28,29,30,31,32*}, Lonette Sandy^33*, Anna Rita Migliaccio, PhD^34,35,36,37, Mohamed E Salama, MD^38,39, Rona Singer Weinberg, PhD⁴⁰, Maureen O'Connor-McCourt, PhD^41*, Gilles Tremblay, PhD^42*, Paul I. Nadler, MD⁴³, Amylou C. Dueck, PhD^2,44,45,46, Ruben A. Mesa, MD, FACP⁴⁷ and Ronald Hoffman, MD^2,48,49,50

¹Icahn School of Medicine at Mount Sinai, New York, NY
²MPN Research Consortium, New York, NY
³Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Hematology, Mount Sinai School of Medicine, New York, NY
⁵Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY
⁶Mayo Clinic, Scottsdale, AZ
⁷Department of Biostatistics, Mayo Clinic, Phoenix, AZ
⁸Division of Hematology and Oncology, Tish Cancer Institute, Ichan School of Medicine at Mount Sinai, New York
⁹Comprehensive Cancer Center of Wake Forest Baptist Health, Winston-Salem, NC
¹⁰Division of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
¹¹Division of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
¹²Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
¹³Moffitt Cancer Center, University of South Florida, Tampa, FL
¹⁴Moffitt Cancer Center, Tampa, FL
¹⁵Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹⁶Leukemia & Myeloid Disorders Program, Cleveland Clinic, Cleveland, OH
¹⁷Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹⁸Taussig Cancer Institute, Department of Hematology & Medical Oncology, Cleveland Clinic, Cleveland, OH
¹⁹Blood and Marrow Transplant Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²⁰Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
²¹Department of Hematology/Oncology, Cleveland Clinic, Cleveland, OH
²²Blood and Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²³Cleveland Clinic Taussig Cancer Institute, Shaker Heights, OH
²⁴Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²⁵Mayo Clinic, Phoenix, AZ
²⁶Division of Hematology and Medical Oncology, Department of Medicine, Mayo Clinic, Phoenix, AZ
²⁷Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ
²⁸Icahn School of Medicine at Mount Sinai, The Tisch Cancer Institute, New York, NY
²⁹Icahn School of Medicine at Mount Sinai, Division of Hematology and Medical Oncology, New York, NY
³⁰Icahn School of Medicine at Mount Sinai, Myeloproliferative Neoplasms Research Consortium, New York, NY
³¹Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD
³²Memorial Sloan Kettering Cancer Center, New York, NY
³³Ichan School of Medicine At Mount Sinai, New York City, NY
³⁴Biomedical and Neuromotorial Sciences, Alma Mater Studiorum University, Bologna, Italy
³⁵Department of Biomedical and Neuromotorial Sciences, Mount Sinai School of Medicine, New York, NY
³⁶Division of Hematology/Oncology, Tisch Cancer Institute, Ichan School of Medicine at Mount Sinai, New York, Italy
³⁷Myeloproliferative Neoplasm-Research Consortium, New York, NY
³⁸Mayo Medical Laboratories, Rochester, MN
³⁹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁴⁰New York Blood Center, New York, NY
⁴¹Forbius, Montreal, Canada
⁴²Formation Biologics, Montreal, QC, Canada
⁴³Nadler Pharma Associates, LLC, Randolph, NJ
⁴⁴Mayo Clinic Arizona, Phoenix, AZ
⁴⁵Section of Biostatistics, Mayo Clinic, Scottsdale, AZ
⁴⁶Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ
⁴⁷Mays Cancer Center at UT Health San Antonio, San Antonio, TX
⁴⁸Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁴⁹Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁵⁰Hematology/Oncology, Mount Sinai School of Medicine, New York, NY

Kimberley Dilley, MD, MPH^1*, Jason Harb, PhD^2*, Muhammad Jalaluddin, PhD^2*, Jessica E. Hutti, PhD^1* and Jalaja Potluri, MD¹

¹AbbVie Inc., North Chicago, IL
²AbbVie, Inc., North Chicago, IL

Peter AW te Boekhorst, MD, PhD^1*, Alexandre Theocharides, MD^2*, Heinz Gisslinger, MD^3*, Timothy Devos, MD⁴, Eric Lippert, MD, PhD^5*, Damianos Sotiropoulos, MD⁶, Miklos Egyed, MD, PhD^7*, Valerio De Stefano, MD^8*, Vincenzo Accurso, MD^9*, Alessandra Iurlo, MD, PhD^10*, Anders E.A. Dahm, MD, PhD^11*, Regina Garcia-Delgado, MD^12*, Nathan Cantoni, MD^13*, Mike Zuurman, PhD^14*, Michael Zaiac, MD^15*, Erik Houtsma, MSc^16*, Amir Iqbal, PhD^16*, Paola Di Matteo, MD, PhD^17* and Alberto Alvarez-Larrán, MD^18*

¹Department of Hematology, Erasmus Medical Center, Rotterdam, Netherlands
²Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
³Haematologie Haemostaseologie Innere Medizin I, AKH Allgemeines Krankenhaus Wien, Vienna, Austria
⁴Department of Microbiology and Immunology, Laboratory of Molecular Immunology (Rega Institute), KU Leuven, Leuven, Belgium; Division of Hematology, University Hospitals Leuven, Leuven, Belgium
⁵Service Hématologie - Bat 3, Hôpital Morvan - CHU de Brest, Brest, France
⁶Heamatology Clinic, General Hospital of Thessaloniki G Papanikolaou, Thessaloniki, Greece
⁷Hematológiai Osztály, Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvar, Hungary
⁸Section of Hematology, Catholic University, Fondazione Policlinico A Gemelli IRCCS, Rome, Italy
⁹U O di Ematologia Divisione di Oncologia, Az Osp Univ Policlinico P Giaccone Universita Studi Palermo, Palermo, Italy
¹⁰Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
¹¹Avdeling for blodsykdommer, Akershus universitetssykehus, Lørenskog, Norway
¹²Servicio de Hematologia, Hospital Virgen de la Victoria, Malaga, Spain
¹³Main Centre, Kantonsspital Aarau AG, Aarau, Switzerland
¹⁴Novartis Pharma BV, Amsterdam, Gelderland, Netherlands
¹⁵Novartis Pharma AG, Basel, Switzerland
¹⁶Novartis Global Service Center, Dublin, Ireland
¹⁷Novartis Farma S.p.A, Origgio, Italy
¹⁸Servicio de Hematologia, Hospital Clinic de Barcelona - GEMFIN, Barcelona, Spain

Blake T. Langlais, MS^1*, Carolyn Mead-Harvey, MS^1*, Heidi E. Kosiorek, MS^1*, Gina L. Mazza, PhD^1*, Ruben Mesa, MD², Jeanne M. Palmer, Md³ and Amylou C. Dueck, PhD¹

¹Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ
²Mays Cancer Center at UT Health San Antonio MD Anderson, San Antonio, TX
³Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ

Michael R. Grunwald, MD¹, Ivy Altomare, MD^2*, Robyn M. Scherber, MD^3,4, Patricia Kalafut, PhD^3*, Haobo Ren, PhD^3* and Srdan Verstovsek, MD, PhD⁵

¹Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
²Division of Medical Oncology, Duke University Medical Center, Durham, NC
³Incyte Corporation, Wilmington, DE
⁴UT Health San Antonio MD Anderson Cancer Center, San Antonio, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Orly Leiva, MD¹, Olesya Baker, PhD^2*, Andrew M. Brunner^3*, Hanny Al-Samkari, MD⁴, Rebecca Karp Leaf, MD⁵, Rachel P. Rosovsky, MD, MPH⁶, Amir T. Fathi, M.D.⁷, James I Weitzman, MD⁸, Larissa Bornikova, MD^9*, Valentina Nardi, MD¹⁰ and Gabriela S. Hobbs, MD¹¹

¹Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
²Center for Clinical Investigation, Brigham and Women's Hospital, Boston, MA
³Center for Leukemia, Massachusetts General Hospital, Boston, MA
⁴Division of Hematology, Massachusetts General Hospital, Dana-Farber Cancer Institute, Harvard University, Boston, MA
⁵Massachusetts General Hospital, Boston, MA
⁶Division of Hematology, Massachusetts General Hospital, Boston, MA
⁷Massachusetts General Hospital , Harvard Medical School, Cambridge, MA
⁸MGH/North Shore Cancer Center, Danvers, MA
⁹Hematology/Oncology, Massachusetts General Hospital, Boston, MA
¹⁰Department of Pathology, Massachusetts General Hospital, Boston, MA
¹¹Leukemia Center, Massachusetts General Hospital, Boston, MA

Sangeetha Venugopal, MD¹, Srdan Verstovsek, MD, PhD¹, Prithviraj Bose, MD¹, Naveen Pemmaraju, MD¹, Lingsha Zhou^1*, Sherry A. Pierce, BSN, BA^1*, Hagop M. Kantarjian, MD², Zeev E. Estrov, MD¹ and Lucia Masarova, MD^1*

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Joan How, MD¹, Yiwen Liu^2*, Jennifer Lombardi Story^3*, Donna S. Neuberg, ScD⁴, Katya Ravid, PhD, DSc⁵, Wolfgang Jarolimek^6*, Brett Charlton^6* and Gabriela S. Hobbs, MD³

¹Dana Farber Cancer Institute / Massachusetts General Hospital, Boston, MA
²Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
³Leukemia Center, Massachusetts General Hospital, Boston, MA
⁴Data Sciences Institute, Dana Farber, Boston
⁵Department of Medicine, Boston Univ. School of Med., Boston, MA
⁶Pharmaxis Ltd, French's Forest, Australia