-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

616.P1.57 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster I

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
AML, Adult, antibodies, apoptosis, Biological, therapy sequence, Diseases, Animal models, bone marrow, CML, Non-Biological, Therapies, CAR-Ts, cell regulation, Combinations, Elderly, checkpoint inhibitors, chemotherapy, MDS, DNA damage, Biological Processes, enzyme inhibitors, MPN, DNA repair, Technology and Procedures, cytogenetics, immunotherapy, Study Population, Myeloid Malignancies, Clinically relevant, NK cells, imaging, pharmacology, flow cytometry, transplantation, inflammation, stem cells, metabolomics, microenvironment, RNA sequencing, pathways, signal transduction
Saturday, December 5, 2020: 7:00 AM-3:30 PM

Andrew Wei, MBBS, PhD1,2, Gail J. Roboz, MD3, Hervé Dombret, MD4,5, Hartmut Döhner6, Andre C. Schuh7,8, Pau Montesinos, MD, PhD9,10*, Christopher Pocock, MBBS11, Dominik Selleslag, MD12, Sergey N. Bondarenko13*, Ignazia La Torre14*, Barry Skikne, MD15,16*, Keshava Kumar, PhD16*, Qian Dong, DrPH16*, C.L. Beach, PharmD16* and Farhad Ravandi, MBBS17

1Department of Clinical Haematology, The Alfred Hospital, Melbourne, Australia
2Monash University, Australian Centre for Blood Diseases, Melbourne, Australia
3Weill Medical College of Cornell University New York-Presbyterian Hospital, New York, NY
4Hôpital Saint-Louis, Assistance Publique – Hôpitaux de Paris (AP-HP), Paris, France
5Institut de Recherche Saint Louis, Université de Paris, Paris, France
6Ulm University Hospital, Ulm, Germany
7University of Toronto, Toronto, Canada
8Princess Margaret Cancer Centre, Toronto, ON, Canada
9CIBERONC, Instituto de Salud Carlos III, Madrid, Spain
10Hospital Universitario y Politécnico La Fe, Valencia, Spain
11Kent & Canterbury Hospital, Canterbury, United Kingdom
12AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium
13RM Gorbacheva Research Institute, Pavlov University, St. Petersburg, Russian Federation
14Celgene, a Bristol-Myers Squibb Company, Boudry, Switzerland
15Kansas University Medical Center, Kansas City, KS
16Bristol Myers Squibb, Princeton, NJ
17Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Amer M. Zeidan, MBBS, MHS1, Pierre Fenaux, MD, PhD2, Marco Gobbi, MD3*, Jiri Mayer4*, Gail J. Roboz, MD5, Jürgen Krauter, MD6*, Tadeusz Robak, MD PhD7, Jan Philipp Bewersdorf, MD8, Hagop M. Kantarjian, MD9, Jan Novak10*, Wieslaw Wiktor Jedrzejczak, MD, PhD11*, Xavier Thomas, MD, PhD12, Mario Ojeda-Uribe13*, Yasushi Miyazaki, MD, PhD14, Yoo Hong Min, MD, PhD15, Su-Peng Yeh, MD16*, Joseph M Brandwein, MD17, Liana Gercheva, MD18*, Judit Demeter, MD19*, Elizabeth A. Griffiths, MD20, Karen W.L. Yee, MD21, Jean-Pierre Issa, MD22*, Yong Hao, MD, PhD23*, Mohammad Azab, MD, MSc, MBA24* and Hartmut Döhner25

1Yale University School of Medicine and Yale Cancer Center, New Haven, CT
2Hôpital Saint-Louis, Paris, France
3IRCCS Ospedale Policlinico San Martino, Genoa, Italy
4University Hospital Brno, Czech Republic, Brno, CZE
5Weill Medical College of Cornell University New York-Presbyterian Hospital, New York, NY
6Department of Internal Medicine III, Städtisches Klinikum Braunschweig, Braunschweig, Germany
7Department of Hematology, Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
8Department of Internal Medicine, Yale University, New Haven, CT
9The University of Texas M.D. Anderson Cancer Center, Houston, TX
10Department of Internal Medicine and Hematology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University, Prague, Czech Republic
11Uniwersyteckie Centrum Kliniczne WUM, Warsaw, Poland
12Centre Hospitalier Universitaire de Lyon-Sud, Lyon, France
13GHR Mulhouse Sud-Alsace, Mulhouse, France
14Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan
15Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of (South)
16Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan
17Division of Hematology, University of Alberta, Edmonton, AB, Canada
18Clinical Hematology Clinic, Multiprofile Hospital for Active Treatment "Sveta Marina", Varna, Bulgaria
19Semmelweis University, Budapest, HUN
20Roswell Park Comprehensive Cancer Center, Buffalo, NY
21Leukemia Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
22Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA
23Astex Pharmaceuticals, Inc., Pleasanton, CA
24Astex Pharmaceuticals, Inc., Pleasanton, NJ
25Ulm University Hospital, Ulm, Germany

Richard M. Stone, MD1, Daniel J. DeAngelo, MD, PhD2, Anthony G. Letai, MD, PhD3, Jeremy M. Stewart, BA2*, Michael McGinnis2*, Francis Brown, JD2*, Geoffrey Fell4*, Yael Flammand5*, Marina Konopleva, MD, PhD6, Jacqueline S. Garcia, MD2 and Marlise R Luskin, MD, MS1

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston
2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
3Department of Medical Oncology, Dana-Farber Cancer Institute & HMS, Boston, MA
4Data Science, Dana-Farber Cancer Institute, Boston, MA
5Biostatistics, Dana-Farber Cancer Institute, Boston, MA
6University of Texas, MD Anderson Cancer Center, Houston, TX

Gail J. Roboz, MD1, Daniel J. DeAngelo, MD, PhD2, David A. Sallman, MD3, Monica L. Guzman, PhD4, Pinkal Desai, MD, MPH5, Hagop M. Kantarjian, MD6, Marina Konopleva, MD, PhD7, Nelli Bejanyan, MD8, Hany Elmariah, MD, MS9, Francisco Javier Esteva, MD, PhD10*, Andrew Garton11*, Kate Backhouse10*, Roman Galetto, PhD12*, Carrie Brownstein, MD10 and Naveen Pemmaraju, MD13

1Weill Cornell Medicine, The New York Presbyterian Hospital, New York, NY
2Department of Medical Oncology, Dana-Farber Cancer Inst., Boston, MA
3H. Lee Moffitt Cancer Center, Tampa, FL
4Division of Hematology and Oncology, Weill Cornell Medical College Division of Hematology/Oncology, New York, NY
5Weill Cornell Medical College, New York, NY
6University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
8Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
9Department of Blood and Marrow Transplantation and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
10Cellectis, New York, NY
11Cellectis Inc, New York
12Cellectis SA, Paris, France
13Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Carlos Bachier, MD1, Gautam Borthakur, MD2, Chitra Hosing, MD3, William Blum, MD4*, Marcello Rotta, MD5, Paulius Ojeras6*, Brian Barnett, MD6*, Kanya Rajangam, MD, PhD6*, Navneet S. Majhail, MD, MS7 and Sarah Nikiforow, MD, PhD8*

1Sarah Cannon Blood Cancer Network, Sarah Cannon Center for Blood Cancer, Nashville, TN
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3University of Texas MD Anderson Cancer Center, Department of Stem Cell Transplantation and Cellular Therapy, Houston, TX
4Winship Cancer Institute of Emory University, Atlanta, GA
5Sarah Cannon Blood Cancer Network, Colorado Blood Cancer Institute, Denver, CO
6Nkarta Therapeutics, South San Francisco, CA
7Department of Hematology and Medical Oncology, Leukemia Program, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
8Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

Naval Daver, MD1, Sreyashi Basu, PhD2*, Guillermo Garcia-Manero, MD3, Hussein A Abbas, MD, PhD4, Marina Konopleva, MD, PhD5, Tapan M. Kadia, MD6, Courtney D. DiNardo, MD, MSc7, Gautam Borthakur, MD3, Ahmad S. Alotaibi, MD1*, Naveen Pemmaraju, MD3, Elias Jabbour, MD3, Sherry A. Pierce, BSN, BA3*, Mark Brandt, BS3*, Koichi Takahashi, MD, PhD8, Jing Ning9*, Steven M. Kornblau, MD10, Koji Sasaki, MD11, Musa Yilmaz, MD11, Ghayas C. Issa, MD12, Nicholas J. Short, MD3, Jairo A. Matthews13*, Wilmer Flores14*, Michael Andreeff, MD, PhD15, Jorge E. Cortes, MD16, Farhad Ravandi, MBBS17, James P Allison, PhD2*, Hagop M. Kantarjian, MD18 and Padmanee Sharma19*

1Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
2Department of Immunology, UT M. D. Anderson Cancer Center, Houston, TX
3Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
4Division of Cancer Medicine, Medical Oncology Fellowship, UT M. D. Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
7Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
8Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
9The University of Texas M.D. Anderson Cancer Center, Houston, TX
10Department of Stem Cell Transplantation, M.D. Anderson Cancer Center University of Texas, Houston, TX
11Department of Leukemia, MD Anderson Cancer Center, Houston, TX
12Department of Leukemia, Universit Y of Texas At Houston, Houston, TX
13Department of Leukemia, UT M. D. Anderson Cancer Center, Houston, TX
14Leukemia, University of Texas - MD Anderson Cancer Center, Houston, TX
15Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
16Georgia Cancer Center Augusta University, Augusta, GA
17Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
18Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
19Department of Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

Rafael Bejar, MD, PhD1,2, Hongying Zhang, MD, PhD1*, Nasrin Rastgoo, PhD1*, Khalid Benbatoul, BS1*, Yuying Jin, PhD1*, Matthew Thayer, BS.1*, Susan Sheng, PhD1*, Gregory k Chow, BA, MBA3*, Victor Montalvo-Lugo1*, Jotin Marango, MD1*, Stephen B Howell, MD2 and William G Rice, PhD1

1Aptose Biosciences, Inc., San Diego, CA
2Moores Cancer Center, University of California San Diego, La Jolla, CA
3Aptose Biosciences Inc., Burlingame, CA

Verena I Gaidzik, MD1, Verena Mayr-Benedikter1*, Daniela Weber, MSc1*, Anika Schrade, PhD1*, Jürgen Krauter, MD2*, Juliane S. Walz, MD3*, Holger Hebart, MD4, Beate S. Schultheis, MD5, Nadezda Basara, MD6, Elisabeth Dietl, MD7*, Silke Kapp-Schwoerer, MD1*, Michaela Feuring-Buske, MD1*, Felicitas Thol8, Michael Heuser8, Stefan Faderl, MD9*, Anthony J. Wagner9*, Maral Saadati10*, Julia Krzykalla, PhD11*, Axel Benner11*, Arnold Ganser8, Konstanze Dohner, MD1, Peter Paschka, MD1 and Hartmut Döhner1

1Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany
2Medizinische Klinik III, Städtisches Klinikum Braunschweig, Braunschweig, Germany
3Klinik für Innere Medizin II, Universitätsklinikum Tübingen, Tübingen, Germany
4Stauferklinikum Mutlangen, Ostalb Kliniken, Mutlangen, Germany
5Medizinische Klinik III - Hämatologie / Onkologie, Marienhospital Herne, Herne, Germany
6Medizinische Klinik I, Malteser Krankenhaus St. Franziskus-Hospital, Flensburg, Germany
7Hämatologie und Onkologie und Palliativmedizin, Klinikum Traunstein, Traunstein, Germany
8Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation, Medizinische Hochschule Hannover, Hannover, Germany
9Jazz Pharmaceuticals, Palo Alto, CA
10Saadati Solutions, Ladenburg, Germany
11Abteilung für Biostatistik, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany

Leanne Lanieri1*, Tahirih L Lamothe, BS1*, Oliver Miske1*, Sean M McDonough2*, Ganapathy N Sarma1*, Prashant Bhattarai1*, Kellie Latimer1*, Junia Dushime1*, Nidhi Jain1*, Rahul Palchaudhuri, PhD1*, Ryan Knihtila1*, Bradley R Pearse, PhD1*, Jennifer L Proctor, BS1*, Anthony E Boitano, PhD1, Michael P Cooke, PhD1 and John C. Davis Jr., MD, MPH, MS1*

1Magenta Therapeutics, Cambridge, MA
2Magenta Therapeutics, Wakefield, MA

Joshua F. Zeidner, MD1, Daniel J. Lee, MD2, Gil Fine, PhD3*, Eunice S. Wang, MD4, Vijaya R. Bhatt, MD5, Andrew Dalovisio, MD6*, Pau Montesinos, MD, PhD7*, Kathryn S. Kolibaba, MD3, Stephen P. Anthony, DO3, David J. Bearss, PhD3 and B. Douglas Smith, MD8

1Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
2Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY
3Sumitomo Dainippon Pharma Oncology, Inc., Lehi, UT
4Roswell Park Comprehensive Cancer Center, BUFFALO, NY
5Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE
6Ochsner Medical Center, New Orleans, LA
7Hematology Department, Hospital Universitario La Fe de Valencia,, Valencia, Spain, Spain
8Johns Hopkins Medical Institutes, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD

Kana Nakatani1*, Hidemasa Matsuo2*, Yutarou Harata3*, Moe Higashitani4*, Asami Koyama3*, Mina Noura5*, Yoko Nishinaka-Arai, PhD2,6*, Yasuhiko Kamikubo3* and Souichi Adachi, MD, PhD3

1Department of Human Health Sciences, Kyoto University, Kyoto-Shi, Japan
2Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto City, Japan
3Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan
4Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, JPN
5Department of Human Health Sciences, Kyoto University, Kyoto, Japan
6Center for iPS cell Research and Application, Center For Ips Cell Research and Application, Kyoto City, Japan

Naval Daver, MD1, Kendra L. Sweet, MD, MS2*, Pau Montesinos, MD, PhD3*, Eunice S. Wang, MD4, Ahmed Aribi, MD5*, Daniel J. DeAngelo, MD, PhD6, Harry P Erba, MD PhD7, Giovanni Martinelli, MD8, Roland P Walter, MD PhD9, Jessica K Altman, MD10, Anjali S Advani, MD11, Antonio Curti, MD PhD12, Callum M Sloss, PhD13, Kara E Malcolm, RN13* and Patrick A Zweidler-McKay, MD, PhD14

1The University of Texas MD Anderson Cancer Center, Houston, TX
2H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
3Hospital Universitari i Politècnic La Fe, Valencia, Spain
4Roswell Park Comprehensive Cancer Center, BUFFALO, NY
5City of Hope National Medical Center, Duarte, CA
6Department of Medical Oncology, Dana-Farber Cancer Inst., Boston, MA
7Duke University School of Medicine, Durham, NC
8Institute of Hematology “L. e A. Seràgnoli”, Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy
9Department of Medicine, University of Washington, Seattle, WA
10Robert H. Lurie Comprehensive Cancer Center, Chicago, IL
11Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
12Azienda Ospedaliero-Universitaria S. Orsola-Malpighi, Bologna, Italy
13ImmunoGen, Waltham, MA
14ImmunoGen, Lincoln, MA

Daria Frank1*, Ashok Kumar Jayavelu, PhD2*, Lanying Wei, M.Sc.1,3*, Yahya Saleh Al-Matary, PhD4*, Pradeep Kumar Patnana, M.Sc.1*, Subbaiah Chary Nimmagadda, PhD1*, Michael Heuser, Prof., MD5*, Felicitas Thol6, Gudrun Gohring, Prof., MD7*, Jürgen Thomale, PhD8*, Anja Pfaus, M.Sc.9*, Roland Rad, Prof., MD9*, Christoph Röllig, Prof., MD10*, Friedrich Stoelzel, PD, MD11, Claudia Dill11*, Heidi Altmann, PhD11*, Desiree Kunadt, MD11*, Christoph Schliemann, Prof., MD1*, Jan-Henrik Mikesch, PD, MD1*, Maria Francisca Arteaga, PhD1*, Wolfgang E. Berdel, Prof., MD1, Georg Lenz1 and Cyrus Khandanpour, PD, MD1

1Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany
2Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, Munich, Bayern, Germany
3Institute of Medical Informatics, Muenster University, Muenster, Germany
4Clinic of Dermatology, University Hospital Essen, Essen, Germany
5Department for Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
6Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
7Department of Human Genetics, Hannover Medical School, Hannover, Germany
8Institute of Cell Biology, University Hospital Essen, Essen, Germany
9Institute of Molecular Oncology and Functional Genomics, Technical University of Munich, Munich, Germany
10Department of Hematology and Oncology, University Hospital Carl Gustav Carus Dresden, Dresden, Germany
11Department of Internal Medicine I, University Hospital Dresden, Dresden, Germany

Helal Mohammed Mohammed Ahmed Noman, MBBS1, Yahya Saleh Al-Matary, PhD2*, Subbaiah Chary Nimmagadda, PhD3*, Maren Fiori4*, Pradeep Kumar Patnana, M.Sc.3*, Daria Frank3*, Lanying Wei, M.Sc.5*, Judith Schütte, PhD3*, Tobias May6*, Joachim R. Goethert, MD4*, Thomas Schroeder, MD7*, Ulrike Buttkereit, PhD4*, Christian Recher, MD, PhD8, Manuel Rodríguez-Paredes9*, Thorsten Koenig10*, Wolfgang Hartmann, MD11*, Jan Tuckermann, PhD12*, Bertram Opalka, PhD4*, Georg Lenz3 and Cyrus Khandanpour, PD, MD3

1Department of Medicine A, University Hospital Muenster, Münster, Germany
2Clinic of Dermatology, University Hospital Essen, Essen, Germany
3Department of Medicine A, University Hospital Muenster, Muenster, Germany
4University Hospital Essen, Essen, Germany
5Institute of Medical Informatics, Muenster University, Muenster, Germany
6InSCREENeX GmbH, Brunswick, Germany
7University Hospital Duesseldorf, Duesseldorf, AL, DEU
8Clinical Hematology, ins, Toulouse, France
9German Cancer Research Center, Heidelberg, Germany
10Institute for Molecular Tumor Biology, University of Münster, Muenster, Germany
11Pathology department, University Hospital Muesnter, Muenster, Germany
12Institute for Molecular Endocrinology of Animals, Ulm, Germany

Tracy Murphy, MD, FRCP, FRCPath1, Brian Leber, MD2, Mark R Bray3*, Steven M Chan, MD, PhD1, Vikas Gupta, MD, FRCP, FRCPath4, Dina Khalaf, BSc, MSc, MD2, Dawn Maze, MD, FRCPC, MSc1, Caroline J McNamara, MBBS1, Aaron D Schimmer, MD, PhD1, Andre C. Schuh1, Hassan Sibai, MBBS1*, Graham Fletcher3*, Debbie Valiquette2*, Kylie Martin, BSc, RN, BSN1*, Mark D. Minden1 and Karen W.L. Yee, MD4

1Princess Margaret Cancer Centre, Division of Medical Oncology and Hematology, University Health Network, University of Toronto, Toronto, ON, Canada
2Division of Hematology, Juravinski Cancer Centre, McMaster University, Hamilton, ON, Canada
3University Health Network, Toronto, ON, Canada
4Leukemia Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Agnieszka Wierzbowska, MD1*, Agnieszka Pluta, MD PhD1*, Marta Antonina Libura, MD PhD2*, Anna Czyz, MD PhD3*, Sebastian Giebel, MD PhD4*, Piotr Stelmach, MD PhD1*, Magdalena Czemerska, MD PhD5*, Anna Kopinska, MD6*, Krzysztof Wozniczka, MD PhD6*, Grzegorz Helbig, MD PhD6*, Karol Wojcik, MD7*, Malgorzata Razny, MD PhD7*, Marta Sobas, MD PhD3*, Tomasz Wrobel, MD PhD3, Andrzej Szczepaniak, MD PhD8*, Lidia Gil, MD PhD9, Jan Zaucha, MD PhD10*, Tomasz Gromek, MD PhD11*, Marek Hus, MD PhD11*, Edyta Cichocka, MD PhD12*, Janusz Halka, MD PhD13*, Elzbieta Patkowska14*, Jolanta Wozniak, PhD15*, Agata Obara, MD16*, Beata Blajer-Olszewska, MD17*, Katarzyna Dulik, MD4*, Jerzy Holowiecki, MD PhD4*, Michal Soin, M.Sc.1*, Tadeusz Robak, MD PhD1, Nicole M. Cruz, MD18, Nuria Mencia-Trinchant, PhD18*, Pinkal Desai, MD, MPH19, Sangmin Lee, MD18, Michael B. Samuel, MD18*, Maria Bieniaszewska10*, Magdalena Dutka, MD10*, Justin D. Kaner, MD18, Ellen Ritchie, MD 20, Monica L. Guzman, PhD21 and Gail J. Roboz, MD22

1Department of Hematology, Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
2Department of Hematology, Oncology and Internal Medicine, Warsaw Medical University, Warsaw, Poland
3Department of Hematology, Wroclaw Medical University, Wroclaw, Poland
4Department of Bone Marrow Transplantation and Hematology-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
5Deaprtment of Hematology, Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
6Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland
7Department of Hematology, Rydygier Memorial Hospital, Krakow, Poland
8Department of Hematology and Bone Marrow Transplantation, University of Medical Sciences, Poznan, Poland
9Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
10Department of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland
11Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland
12Department of Hematology, Copernicus Memorial Hospital, Torun, Poland
13Department of Hematology, Warmian-Masurian Cancer Center of The Ministry of the Interior and Administration’s Hospital, Olsztyn, Poland
14Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
15Division of Hematological Diagnostics, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
16Department of Hematology, Holly Cross Oncology Center, Kielce, Poland
17Department of Hematology, Chopin Memorial Teaching Hospital No 1, Rzeszów, Poland
18Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
19Weill Cornell Medical College, New York, NY
20Weill Cornell Medicine, New York, NY
21Division of Hematology and Oncology, Weill Cornell Medical College Division of Hematology/Oncology, New York, NY
22Weill Medical College of Cornell University New York-Presbyterian Hospital, New York, NY

Silvia Maifrede1*, Bac Viet Le1*, Margaret Nieborowska-Skorska1*, Konstantin Golovine1*, Katherine Sullivan-Reed1*, Wangisa M.B. Dunuwille2*, Joseph Nacson3*, Michael Hulse1*, Lisa Beatrice Caruso1*, Zachary Gazze1*, Zhaorui Lian1*, Antonella Padella4*, Kumaraswamy Chitrala1*, Boris Bartholdy5*, Ksenia Matlawska-Wasowska6*, Daniela Di Marcantonio3, Giorgia Simonetti7*, Georg Greiner8*, Stephen M. Sykes3, Peter Valent, MD9, Elisabeth M. Paietta10*, Hugo F Fernandez11*, Martin S. Tallman, MD 12, Mark Litzow, MD13, Mark D. Minden14, Jian Huang1, Giovanni Martinelli, MD4, George S. Vassiliou, MD, PhD, FRCPath, MRCP15*, Italo Tempera1*, Katarzyna Piwocka16*, Neil Johnson3*, Grant Challen17 and Tomasz Skorski, MD, PhD1

1Temple University School of Medicine, Philadelphia, PA
2Washington University School of Medicine, Saint Louis
3Fox Chase Cancer Center, Philadelphia, PA
4University of Bologna, Meldola, Italy
5Albert Einstein College of Medicine, Bronx, NY
6University of New Mexico, Albuquerque, NM
7University of Bologna, Bologna, Italy
8Medical University of Vienna, Vienna, Austria
9Department of Medicine I, Division of Hematology, Medical University of Vienna, Vienna, Austria
10Albert Einstein College of Medicine, New York, NY
11Moffitt Malignant Hematology & Cellular Therapy at Memorial Healthcare System, Pembroke Pines
12Memorial Sloan-Kettering Cancer Center, New York, NY
13Division of Hematology, Mayo Clinic, Rochester, MN
14Leukemia Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
15Wellcome Trust Sanger Institute, Cambridge, ENG, United Kingdom
16Nencki Institute of Experimental Biology, Warsaw, Poland
17Washington University School of Medicine, St Louis, MO

Shaker A Mousa, PhD, MSc, BPharm, MBA1,2, Noureldien Darwish, MBBCh, PhD3 and Thangirala Sudha, PhD4*

1The Pharmaceutical Research Institute, ACPHS, Prof, Rensselaer, NY
2NanoPharmaceuticals LLC, Rensselaer, NY
3The Pharmaceutical Research Institute, ACPHS, Albany, NY
4The Pharmaceutical Research Institute, ACPHS, Rensselaer, NY

Jonathan Canaani, MD1, Ivetta Danilesko, MD2*, Noga Shem-Tov, MD3*, Maya Zlotnick, MD4*, Kira Lozinsky5*, Ohad Benjamini4*, Ronit Yerushalmi, MD4, Meital Nagar, PhD6*, Chen Dor, PhD5*, Avichai Shimoni, MD7*, Abraham Avigdor, MD8 and Arnon Nagler, MD9

1Hematology Division, Sheba Medical Center, Givatayim, Israel
2Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center,, Ramat-Gan, Israel
3Division of Hematology and Bone Marrow Transplantation,, Chaim Sheba Medical Center, Ramat-Gan, Israel
4Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat Gan, Israel
5Hematology, Chaim Sheba Medical Center, Ramat Gan, Israel
6Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat-Gan, Israel
7Division of Hematology, Sheba Medical Center, Ramat Gan, Israel
8Institute of Hematology, Sheba Medical Center, Ramat Gan, Israel
9Division of Hematology, Sheba Medical Center, Tel Hashomer, Israel

Tomasz Zal, PhD, MSc1, Rafal Zielinski, PhD2*, Krzysztof Grela, MSc2*, Roberto Cardenas-Zuniga2*, Stanislaw Skora, PhD2*, Izabela Fokt, PhD2*, Malgorzata Anna Zal, MSc3*, Michael Andreeff, MD, PhD4, Lidia Gil, MD PhD5, Robert Shephard, MD, PhD6* and Waldemar Priebe, PhD2*

1Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
4Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
6Moleculin Biotech, Inc., Houston, TX

Christopher J. Hindley, PhD1*, Lynsey Fazal, BSc1*, Joanne M. Munck, PhD1*, Vanessa Martins, BSc1*, Alpesh D. Shah, MSci1*, Nicola E. Wilsher, PhD1*, Nicola G. Wallis, PhD1*, Harold N. Keer, MD, PhD2 and John F. Lyons, PhD1*

1Astex Pharmaceuticals, Cambridge, United Kingdom
2Astex Pharmaceuticals, Inc., Pleasanton, CA

Aaron D Goldberg, MD, PhD1, Mark B. Geyer, MD2, Jonathan Kell, MD3, Eros Di Bona, MD4*, Timothy S. Pardee, MD, PhD5, Rupali Bhave, M.D.6*, Michael R. Grunwald, MD7, Giovanni Marconi, MD8, Yijia Wang, MD, MPH9*, Asif Pathan, PhD, RPh9* and Boo Messahel, MD9*

1Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY
2Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
3Department of Haematology, University Hospital of Wales, Cardiff, United Kingdom
4Hematology Department, San Bortolo Hospital, Azienda ULSS8 "Berica" di Vicenza, Vicenza, Italy
5Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston Salem, NC
6Comprehensive Cancer Center of Wake Forest Baptist Health, Winston-Salem, NC
7Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
8Istituto di Ematologia e Oncologia Medica "Lorenzo e Ariosto Seràgnoli" Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
9Arog Pharmaceuticals, Plano, TX

Mike J Donio*, W. Casey Wilson, PhD*, Isra Darwech*, Gabriela Andrejeva, PhD*, Benjamin J Capoccia, PhD*, Robyn J Puro, PhD*, Arun K Kashyap, PhD* and Daniel S Pereira, PhD

Arch Oncology, St Louis, MO

Jayna J Mistry, BSc1*, Charlotte Hellmich2*, Amelia Lambert3*, Jamie A Moore, BSc, MSc4*, Aisha Jibril, BSc5*, Angela Collins, MBBS6*, Federica Di Palma, PhD7*, Kristian M Bowles, MBBS, PhD5,6 and Stuart A Rushworth, PhD5

1Norwich Medical School, The University of East Anglia, Leicester, United Kingdom
2The University of East Anglia, Norwich, GBR
3The University of East Anglia, Norwich, United Kingdom
4Norwich Medical School, The University of East Anglia, Attleborough, ENG, United Kingdom
5Norwich Medical School, University of East Anglia, Norwich, United Kingdom
6Department of Haematology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, United Kingdom
7Earlham Institute, Norwich, United Kingdom

Lindsay Wilde, MD, Ubaldo Martinez-Outschoorn, MD*, Neil Palmisiano, MD, MS, Gina Keiffer, MD and Margaret Kasner, MD, MSc

Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA

*signifies non-member of ASH