Francesca Gay, MD, Pellegrino Musto, Delia Rota Scalabrini^*, Monica Galli^*, Angelo Belotti, MD^*, Elena Zamagni, MD^*, Luca Bertamini, MD^*, Renato Zambello^*, Micol Quaresima^*, Giovanni De Sabbata^*, Giuseppe Pietrantuono^*, Mattia D'Agostino, MD^*, Daniela Oddolo^*, Andrea Capra^*, Anna Marina Liberati^*, Salvatore Palmieri^*, Franco Narni, Massimo Offidani, Michele Cavo^* and Mario Boccadoro

GIMEMA, European Myeloma Network, Italy

Michele Cavo^1*, Francesca Gay, MD², Meral Beksac, MD³, Meletios A Dimopoulos⁴, Lucia Pantani, MD, PhD^1*, Maria Teresa Petrucci⁵, Luca Dozza, MSc^1*, Bronno Van Der Holt, PhD^6*, Sonja Zweegman, MD, PhD⁷, Elena Zamagni, MD^1*, Giuseppe A. Palumbo, MD, PhD^8*, Francesca Patriarca^9*, Monica Galli^10*, Vladimir Maisnar, MD, PhD, MBA^11*, Markus Hansson, MD^12*, Angelo Belotti, MD^13*, Ludek Pour, MD^14*, Paula F Ypma, MD, PhD^15*, Mariella Grasso^16*, Sandra Croockewit, MD^17*, Massimo Offidani¹⁸, Renato Zambello^19*, Anna Marina Liberati, MD²⁰, Niels Frost Andersen, MD, PhD^21*, Annemiek Broyl, MD, PhD^22*, Rossella Troia, PharmD^2*, Pellegrino Musto²³, Heinz Ludwig, MD²⁴, Anna Maria Morelli, M.D^25*, Roman Hajek, MD²⁶, Christoph Driessen, MD²⁷, Anders Waage, MD, PhD²⁸, Peter Gimsing, DO, PhD^29*, Ulf-Henrik Mellqvist, MD, PhD³⁰, Thilo Zander, MD^31*, Mario Boccadoro² and Pieter Sonneveld, MD, PhD³²

¹Seràgnoli Institute of Hematology, Department of Experimental, Diagnostic and Experimental Medicine, Bologna University School of Medicine, S. Orsola Malpighi Hospital, Bologna, Italy
²Myeloma Unit, Division of Hematology, University of Torino, Torino, Italy
³Ankara University School of Medicine Department of Hematology, Ankara, Turkey
⁴University of Athens School of Medicine, KIFISIA, Greece
⁵5Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
⁶HOVON Data Center, Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
⁷Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Hematology, Cancer Center Amsterdam, Amsterdam, Netherlands
⁸Department of Medical, Surgical and Advanced Technology "G.F. Ingrassia", University of Catania, Catania, Italy
⁹Clinical Hematology and Bone Marrow Transplant Centre, S Maria della Misericordia University Hospital, DAME, University of Udine, Udine, Italy
¹⁰Hematology, Papa Giovanni XXIII Hospital, Bergamo, Italy
¹¹4th Department of Medicine - Haematology, Charles University Hospital, Hradec Kralove, Czech Republic
¹²Department of Hematology, Skåne University Hospital, Lund, Sweden
¹³Hematology, SC Ematologia e Dipartimento di Oncologia Clinica, A.O. Spedali Civili di Brescia, Brescia, Italy
¹⁴University Hospital Brno, Brno, Czech Republic
¹⁵Haga Hospital, The Hague, Netherlands
¹⁶Divisione di Ematologia, Ospedale Civico Santa Croce e Carle, Cuneo, ITA
¹⁷Radboud University Medical Centre, Nijmegen, NLD
¹⁸18Clinica di Ematologia, AOU Ospedali Riuniti di Ancona, Ancona, Italy
¹⁹Hematology and Clinical Immunology, Department of Medicine, Azienda Ospedaliera di Padova, Padova, Italy
²⁰Università degli Studi di Perugia, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy
²¹Department of Hematology, Aarhus University Hospital, Aarhus, Denmark
²²Erasmus MC Cancer Institute, Rotterdam, Netherlands
²³Department of Emergency and Organ Transplant, University of Bari, Bari, Italy
²⁴Wilhelminen Cancer Research Institute, Vienna, Austria
²⁵Clinical Hematology, Department of Hematology, Transfusion Medicine and Biotechnology, “Spirito Santo” Civic Hospital, Pescara, Italy
²⁶Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic
²⁷Clinics for Medical Oncology and Haematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
²⁸Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
²⁹Department of Hematology, Rikshospitalet, Copenhagen, Denmark
³⁰Department of Hematology, South Älvsborg Hospital, Boras, Sweden
³¹Medical Oncology, Luzerner Kantonsspital, Luzern, Switzerland
³²Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands

Aurore Perrot, MD, PhD^1*, Valerie Lauwers-Cances^2*, Titouan Cazaubiel^3*, Thierry Facon, MD^4*, Denis Caillot^5*, Lauriane Clement-Filliatre^6*, Margaret Macro^7*, Olivier Decaux^8*, Karim Belhadj, MD^9*, Mohamad Mohty¹⁰, Lionel Karlin, MD^11*, Jean Claude Eisenmann^12*, Mourad Tiab^13*, Frederique Orsini^14*, Cyrille Touzeau^15*, Xavier Leleu, MD¹⁶, Herve Avet-Loiseau¹⁷, Nikhil C. Munshi, MD¹⁸, Kenneth Anderson, MD¹⁹, Paul G. Richardson, MD²⁰, Philippe Moreau^21* and Michel Attal²²

¹CHU de Toulouse, IUCT-O, Université de Toulouse, UPS, Service d’Hématologie, Toulouse, France
²USMR, service d'Epidemiologie, CHU Toulouse, Toulouse, France
³CHU de Bordeaux, Service d'Hématologie et de Thérapie Cellulaire, Bordeaux, France
⁴Centre Hospitalier Universitaire (CHU) Lille, Service des Maladies du Sang, University of Lille, Lille, France
⁵CHU de Dijon, Service d'Hématologie, Dijon, France
⁶CHU de Nancy, Service d'Hématologie, Nancy, France
⁷Service d'Hématologie, CHU de Caen, Caen, France
⁸Service d'Hématologie, CHU de Rennes, Rennes, France
⁹Lymphoid Malignancies, Centre Hospitalier Universitaire Henri Mondor, Créteil, France
¹⁰Hôpital Saint Antoine, Service d'Hématologie et Thérapie Cellulaire, Paris, Paris, France
¹¹Hématologie, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, Pierre-Bénite, France
¹²Centre Hospitalier de Mulhouse, MULHOUSE, FRA
¹³CH la Roche Sur Yon, La Roche Sur Yon Cedex 9, France
¹⁴Service Hématologie, CH Annecy, ANNECY, France
¹⁵Hématologie, CHU de Nantes, Nantes, France
¹⁶CHU de Poitiers - Hôpital La Milétrie, Service d'Hématologie et Thérapie Cellulaire, Pôle Régional de Cancérologie, POITIERS, France
¹⁷Unite de Genomique du Myelome, IUC-T Oncopole, Toulouse, France
¹⁸Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
¹⁹Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²⁰Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²¹Department of Hematology, University Hospital of Nantes, Nantes, France
²²Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France

Raija Helena Silvennoinen, MD, PhD^1,2, Anders Waage, MD, PhD³, Valdas Peceliunas, MD^4*, Fredrik Schjesvold, MD, PhD⁵, Pekka Anttila, MD^1*, Marjaana Säily, MD, PhD^6*, Mervi Putkonen, MD, PhD^7*, Kristina Carlson, MD^8*, Einar Haukaas, MD^9*, Marja Sankelo, MD, PhD^10*, Anu Partanen, MD, PhD^2*, Damian L. Szatkowski, MD, PhD, MSc^11*, Markus Hansson, MD, PhD^12*, Anu Marttila, MD^13*, Lucia Ahlberg, MD^14*, Per Axelsson, MD^15*, Birgitta Lauri, MD^16*, Maija Helena Mikkola, MD^17*, Conny Karlsson, MD^18*, Johanna Abelsson, MD^19*, Erik Ahlstrand, MD, PhD^20*, Anu Sikiö, MD^21*, Monika Klimkowska, MD, PhD^22*, Reda Matuzeviciene, MD, PhD^23*, Mona Hoysaeter Fenstad, MD, PhD^24*, Sorella Ilveskero, MD, PhD^25* and Hareth Nahi, MD, PhD^26*

¹Helsinki University Hospital, Comprehensive Cancer Center Hematology and University of Helsinki, Helsinki, Finland
²Department of Medicine, Kuopio University Hospital, Kuopio, Finland
³Department of Clinical and Molecular Medicine, St. Olavs Univ. Hospital, Trondheim, Norway
⁴Department of Hematology, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
⁵Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
⁶Department of Internal Medicine, Hematology-Oncology Unit, Oulu University Hospital, Oulu, Finland
⁷Dept of Clinical Hematology, Turku University Hospital and University of Turku, Turku, Finland
⁸Department of Hematology, Uppsala University, Faculty of Medicine and Uppsala University Hospital, Uppsala, Sweden
⁹Stavanger University Hospital, Stavanger, Norway
¹⁰Department of Hematology, Tampere University Hospital, Tampere, Finland
¹¹Førde Central Hospital, Førde, Norway
¹²Skåne University Hospital, Department of Hematology, Lund, Sweden
¹³Department of Medicine, Kymenlaakso Central Hospital, Kotka, Finland
¹⁴Department of Hematology, Linköping University Hospital, Linköping, Sweden
¹⁵Helsinborg Hospital, Hematology, Helsingborg, Sweden
¹⁶Department of Hematology, Sunderby Hospital, Sunderby-Luleå, Sweden
¹⁷Department of Hematology, Paijat-Hame Central Hospital, Lahti, Finland
¹⁸Halland Hospital Hematology, Halmstad, Sweden
¹⁹Uddevalla Hospital, Uddevalla, Sweden
²⁰Department of Hematology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
²¹Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland
²²Department of Clinical Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
²³Biomedical Sciences Institute, Dept of Physiology, Biochemistry, Microbiology and Laboratory Medicine, Vilnius University Hospital and Vilnius University Faculty of Medicine, Vilnius, Lithuania
²⁴Department of Immunology and Transfusion Medicine, St Olavs Hospital, Trondheim, Norway
²⁵Clinical Chemistry, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
²⁶Department of Medicine, Division of Hematology, Karolinska University Hospital of Huddinge, Karolinska Institutet Huddinge, Stockholm, Sweden

Angelo Belotti, MD^1*, Rossella Ribolla, MD^2*, Valeria Cancelli, MD^3*, Alberta Villanacci^4*, Valentina Angelini^5*, Samantha Ferrari^6*, Annalisa Peli, MD^7*, Chiara Cattaneo, MD^8*, Marco Chiarini, MSc^9*, Luigi Grazioli, MD^10*, Giuseppe Rossi, MD³ and Alessandra Tucci, MD^3*

¹Hematology, SC Ematologia e Dipartimento di Oncologia Clinica, A.O. Spedali Civili di Brescia, Brescia, Italy
²Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
³Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
⁴Radiology, ASST Spedali Civili di Brescia, Brescia, Italy
⁵Radiology, ASST Spedali Civili di Brescia, BRESCIA, Italy
⁶Spedali Civili di Brescia, Hematology Division, Italy, Brescia, Italy
⁷Department of Hematology, Spedali Civili, Brescia, Italy
⁸ASST Spedali Civili, Brescia, Italy
⁹Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili di Brescia, Brescia, Italy
¹⁰Department of Radiology, ASST- Spedali Civili di Brescia, brescia, Italy

Madiha Iqbal, MBBS¹, Yennifer Gil^1*, Jonas Paludo, MD², Allison C. Rosenthal, D.O.³, Zhou Li, MS^4*, Manuel Beltran^1*, David J. Inwards, MD², Luis F. Porrata, MD², Ivana Micallef, MD², Jose C Villasboas, MD⁵, Patrick B. Johnston, MD/ PhD⁵, Stephen M. Ansell, MD, PhD⁶, Craig B. Reeder, MD⁷, Hemant S. Murthy, MD¹, Vivek Roy, MD¹, James M. Foran, MD⁸, Han W. Tun, MD¹, Mohamed A. Kharfan-Dabaja, MD, MBA¹ and Ernesto Ayala, MD¹

¹Division of Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL
²Division of Hematology, Mayo Clinic, Rochester, MN
³Mayo Clinic, Phoenix, AZ
⁴Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL
⁵Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
⁶Mayo Clinic, Rochester, MN
⁷Mayo Clinic, Scottsdale, AZ
⁸Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL