-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614.O2.6 614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Targeted Therapies Clinically Relevant Abstract

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
ALL, antibodies, Biological, Leukemia, Diseases, Lymphoma (any), Non-Biological, Combinations, Therapies, chemotherapy, Pediatric, Biological Processes, Young Adult, immunotherapy, Lymphoid Malignancies, Study Population, Clinically relevant, immune mechanism, TKI
Sunday, December 6, 2020: 2:00 PM-3:30 PM
Moderators:
Clare J Rowntree, University Hospital of Wales and Noelle V. Frey, MD, MS, University of Pennsylvania
Disclosures:
No relevant conflicts of interest to declare.
2:00 PM

Nicholas J. Short, MD1, Hagop M. Kantarjian, MD1, Farhad Ravandi, MBBS1, Xuelin Huang, PhD2*, Alessandra Ferrajoli, MD1, Tapan M. Kadia, MD1, Philip A. Thompson, MB, MS1, Yesid Alvarado, MD1, Nitin Jain, MD1, Musa Yilmaz, MD1, Joseph D. Khoury, MD3, Jeffrey L. Jorgensen, MD, PhD4*, Sa A Wang, MD4*, Steven M. Kornblau, MD1, Marina Konopleva, MD, PhD1, Guillermo Garcia-Manero, MD1, Heather M Schroeder1*, Monica Kwari, BSN1, Shilpa Paul, PharmD5*, Benjamin Nwakanme1*, Christopher Loiselle, BS1*, Rebecca Garris, MSc1*, Susan M. O'Brien, MD6 and Elias Jabbour, MD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
6UCI Cancer Center, Orange, CA

2:15 PM

Nicholas J. Short, MD1, Marina Konopleva, MD, PhD1, Elias Jabbour, MD1, Tapan M. Kadia, MD1, Naval Daver, MD2, Robin Cook, RN1*, Nitin Jain, MD1 and Farhad Ravandi, MBBS1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX

2:30 PM

Jeffrey E. Rubnitz, MD1, Thomas B. Alexander, MD, MPH2, Theodore W. Laetsch, MD3*, Seong Lin Khaw, MD4*, Vinod A. Pullarkat, MD5, Joseph T. Opferman, PhD6*, Kathryn G Roberts, PhD7, Lindsey Rosenwinkel8*, Bo Tong, PhD9*, John C. Pesko, PhD8*, Mohamed Badawi8*, Deeksha Vishwamitra, PhD8*, Su Young Kim9*, Charles G Mullighan, MBBS, MD7 and Norman J. Lacayo, MD10

1Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN
2Department of Pediatrics, University of North Carolina, Chapel Hill, NC
3Department of Pediatrics, The University of Texas Southwestern Medical Center/Children's Health, Dallas, TX
4Royal Children’s Hospital, Victoria, Australia
5Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA
6Department of Cell & Molecular Biology, St. Jude's Children's Research Hospital, Memphis, TN
7Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
8AbbVie, Inc., North Chicago, IL
9AbbVie Inc., North Chicago, IL
10Department of Pediatrics- Hematology/Oncology, Stanford University, Palo Alto, CA

2:45 PM

Line Stensig Lynggaard, MD1*, Sofie Gottschalk Højfeldt, MD, PhD2*, Lisbeth Moeller, PhD3*, Goda Elizabeta Vaitkeviciene, MD, PhD4*, Cecilia Langenskiöld, MD5*, Anne Kristine Lehmann, MD6*, Kristi Lepik, MD7*, Päivi Maria Lähteenmäki, MD, PhD8*, Kjeld Schmiegelow, Professor, MD, DMSc9 and Birgitte Klug Albertsen, MD, PhD, professor associate10*

1Aarhus University Hospital, Aarhus N, Denmark
2Child and Adolescent Health, Aarhus University Hospital, Aarhus N., Denmark
3Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Copenhagen, Denmark
4Center of Pediatric Oncology and Hematology, Children's hospital, affiliation of Vilnius University Hospital Santaros Klinikos and Vilnius University, Vilnius, Lithuania
5Institute of Clinical Sciences, Gothenburg University, Gothenburg, SWE
6Haukeland universitetssjukehus, Department of hematology, Bergen, NOR
7Department of Hematology and Oncology, Tallinn Children's Hospital, Tallinn, Estonia
8Department of Pediatric and Adolecent Medicine, Turku University Hospital, Turku, Finland
9The Institute of Clinical medicine, The Faculty of Medicine, University of Copenhagen, Hellerup, Denmark
10Children and Adolescent Health, Aarhus University Hospital, Aarhus, Denmark

3:00 PM

Liora M. Schultz, MD1, Christina Baggott, RN, PhD2*, Snehit Prabhu, PhD3*, Holly Pacenta, MD4, Christine L Phillips, MD5, Jenna Rossoff, MD6, Heather Stefanski, MD, PhD7, Julie-An Talano, MD8, Amy Moskop, MD8, Steven P. Margossian, MD, PhD9, Michael R Verneris, MD10, Gary Douglas Myers, MD11*, Nicole Karras, MD12*, Patrick A. Brown, MD13, Muna Qayed, MD, MSc14, Michelle Hermiston, MD, PhD15, Prakash Satwani, MD16*, Christa Krupski, DO, MPH17*, Amy Keating, MD18*, Rachel Wilcox19*, Cara A Rabik, MD, PhD20, Vanessa Fabrizio, MD21, Michael Kunicki22*, Vasant Chinnabhandar, MD7*, A. Yasemin Goksenin, MD, PhD, MA, MPH23*, Kevin J. Curran, MD24, Crystal L. Mackall, MD25,26,27 and Theodore W. Laetsch, MD28*

1Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA
2Stanford University School of Medicine, Stanford, CA
3Stanford University School of Medicine, Stanford Cancer Institute, Stanford, CA
4Cook Children's Medical Center, Fort Worth, TX
5Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
6Division of Pediatric Hematology/Oncology/Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
7Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN
8Medical College of Wisconsin, Milwaukee, WI
9Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
10University of Colorado, Anschutz Medical Campus, Colorado Children’s Hospital, Aurora, CO
11Children's Mercy Hospital, Kansas City, MO
12Department of Pediatrics, City of Hope National Medical Center, Duarte, CA
13Johns Hopkins School of Medicine, Baltimore, MD
14Emory University, Atlanta, GA
15University, San Francisco, CA
16Division of Pediatric Hematology, Oncology, and Stem Cell Transplant, Department of Pediatrics, Columbia University Medical Center, New York, NY
17Cincinnati Children's Hospital Medical Center, Cincinnati, OH
18University of Colorado, Anschutz Medical Campus Colorado Children’s Hospital, Aurora, CO
19Childern's Mercy Hospital, Kansas
20The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
21Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
22Stanford University School of Medicine, Department of Pediatrics, Division of Hematology and Oncology, Palo Alto, CA
23UCSF Benioff Children’s Hospital, San Francisco, CA
24Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY
25Department of Pediatrics, Division of Hematology and Oncology, Stanford University, Stanford, CA
26Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA
27Center for Cancer Cell Therapy, Stanford University School of Medicine, Stanford, CA
28Department of Pediatrics, The University of Texas Southwestern Medical Center/Children's Health, Dallas, TX

3:15 PM

Andrej Lissat, MD1*, Despina Maniotis1*, Michael Nosswitz1*, Julia Alten, MD2*, Silvia Jenni, PhD3*, Yi-Chien Tsai4*, Gunnar Cario, MD, PhD5*, Roberta La Starza, MD PhD6*, Ondrej Hrusak, MD, PhD7, Andreas E. Kulozik, MD, PhD8*, Olaf Witt9*, Martin Stanulla, MD10*, Martin Schrappe, MD PhD11, Christian M. Zwaan, MD, PhD12, Cornelia Eckert, PhD13*, Arend von Stackelberg, MD14, Andre Baruchel15*, Elad Jacoby, MD16, Axel Karow17*, Francesco Ceppi, MD18, Beat Bornhauser1* and Jean-Pierre Bourquin, MD, PhD19

1University Children's Hospital Zurich, Zurich, Switzerland
2Dept. of Pediatrics, UKSH, Kiel, DEU
3Department of Pediatric Oncology, Children’s Research Centre, University Children’s Hospital Zurich, Zurich, Switzerland
4Universit Children's Hospital Zurich, zurich, Switzerland
5Department of Pediatrics I, Pediatric Hematology/Oncology, ALL-BFM Study Group, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
6University degli Studi di Perugia, Perugia, Italy
7CLIP - Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Charles University CLIP, Prague, Czech Republic
8University of Heidelberg, Heidelberg, Germany
9KiTZ Heidelberg, Heidelberg, Germany
10Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany
11Pediatric Hematology/Oncology, ALL-BFM Study Group, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, Germany, Kiel, Germany
12Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
13Department of Pediatric Oncology/Hematology, Campus Rudolf Virchow, Charité University Hospital, Berlin, Germany
14Department of Pediatric Oncology/Hematology, Charite Medical Center, Berlin, Germany
15IRSL, EA3518 Leukemia Translational Laboratory, Paris, France
16The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel
17Friedrich-alexander-universitäT Erlangen-nüRnberg (FAU), Erlangen, DEU
18Unité D'hémato-Oncologie Pédiatrique, Lausanne, Switzerland
19Universitaets-Kinderspital Zurich, Zurich, Switzerland

*signifies non-member of ASH