-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

Late-Breaking Abstracts Session

Program: General Sessions
Tuesday, December 10, 2019: 7:30 AM-9:00 AM
Hall D, Level 2 (Orange County Convention Center)

Lecture Title:
Late Breaking Abstracts

Co-chairs:
Elisabeth Battinelli, MD, PhD, Brigham and Women's Hospital and Jason Gotlib, MD, MS, Stanford Cancer Center
Disclosures:
Gotlib: Seattle Genetics: Research Funding; Pharmacyclics: Research Funding; Promedior: Research Funding; Novartis: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Incyte: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Gilead: Membership on an entity's Board of Directors or advisory committees, Research Funding; Deceiphera: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Blueprint Medicines: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Allakos: Honoraria, Membership on an entity's Board of Directors or advisory committees.
This highly anticipated session highlights the Program Committee's selections of the highest-impact abstracts, featuring substantive, novel, and groundbreaking data that were not available by the general abstract submission deadline and would otherwise not be presented at the ASH annual meeting.

Patrick A. Brown, MD1, Lingyun Ji, PhD2*, Xinxin Xu, MS3*, Meenakshi Devidas, PhD4*, Laura Hogan, MD5, Michael J. Borowitz, MD, PhD6, Elizabeth A. Raetz, MD7, Gerhard Zugmaier8, Elad Sharon, MD, MPH9*, Lia Gore, MD10, James A. Whitlock, MD11, Michael A. Pulsipher, MD12, Stephen P. Hunger, MD13 and Mignon L. Loh, MD14

1Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
2Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Los Angeles
3Children's Oncology Group, Monrovia, CA
4Department of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN
5Stony Brook Children's, Stony Brook, NY
6Departments of Pathology and Oncology, Johns Hopkins University, Baltimore, MD
7Pediatric Hematology/Oncology, Laura and Isaac Perlmutter Cancer Cent at NYU Langone, New York, NY
8Amgen Research (Munich) GmbH, Munchen, Germany
9Division of Cancer Treatment and Diagnosis, National Cancer Institute, Cancer Therapy Evaluation Program, Bethesda, MD
10Peds Heme/Onc/BMT-CT, University of Colorado, Children's Hospital Colorado, Aurora, CO
11Hospital For Sick Children, Toronto, ON, CAN
12Children’s Center for Cancer and Blood Diseases, Blood and Marrow Transplantation Section, Children’s Hospital Los Angeles, Los Angeles, CA
13Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA
14Department of Pediatrics, University of California Benioff Children’s Hospital, San Francisco, CA

Alexander Roeth, MD1, Wilma Barcellini2*, Shirley D'Sa3*, Yoshitaka Miyakawa4, Catherine M Broome, MD5, Marc Michel6*, David J. Kuter7, Bernd Jilma8, Tor Henrik Anderson Tvedt9, Stella Lin10*, Xiaoyu Jiang10*, Caroline Reuter10*, William Hobbs10 and Sigbjørn Berentsen11*

1Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
2Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy
3UCLH Centre for Waldenström’s Macroglobulinemia and Related Conditions, University College London Hospitals NHS Foundation Trust, London, United Kingdom
4Thrombosis and Hemostasis Center, Saitama Medical University Hospital, Saitama, Japan
5Division of Hematology, MedStar Georgetown University Hospital, Washington, DC
6Henri-Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, UPEC, Créteil, France
7Division of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
8Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
9Section for Hematology, Department of Medicine, Haukeland University Hospital, Bergen, Norway
10Sanofi, Waltham, MA
11Department of Research and Innovation, Haugesund Hospital, Haugesund, Norway

Andrew H. Wei, MBBS, FRACP, FRCPA, PhD1,2*, Hartmut Döhner, MD3, Christopher Pocock, MBBS4, Pau Montesinos, MD, PhD5,6*, Boris Afanasyev, MD, DSci7*, Hervé Dombret, MD8,9,10, Farhad Ravandi, MD11, Hamid Sayar, MD, MSc12, Jun Ho Jang, MD, PhD13, Kimmo Porkka, MD14, Dominik Selleslag, MD15, Irwindeep Sandhu, MD16*, Mehmet Turgut, MD17*, Valentina Giai, MD18*, Yishai Ofran, MD19,20, Merih Kizil Cakar, MD21*, Aida Botelho de Sousa, MD22*, Justyna Rybka, MD, PhD23*, Chiara Frairia, MD24*, Lorenza Borin, MD25*, Germana Beltrami, MD26*, Jaroslav Cermak, MD, PhD27*, Gert J. Ossenkoppele, MD, PhD28, Ignazia La Torre, MD29*, Barry Skikne, MD29*, Keshava Kumar, PhD29*, Qian Dong, DrPH29*, CL Beach, PharmD29 and Gail J. Roboz, MD30,31

1The Alfred Hospital, Melbourne, AUS
2Monash University, Melbourne, Australia
3Ulm University Hospital, Ulm, Germany
4Kent & Canterbury Hospital, Canterbury, United Kingdom
5CIBERONC, Instituto Carlos III, Madrid, Spain
6Hospital Universitari i Politècnic La Fe, Valenica, Spain
7Raisa Gorbacheva Memorial Research Institute for Pediatric Oncology, Hematology and Transplantation, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Ru, Russian Federation
8Hematology, Hôpital Saint-Louis, Paris, France
9Institut de Recherche Saint Louis, Paris, France
10Université de Paris, Paris, France
11Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
12Indiana University Cancer Center, Indianapolis, IN
13Samsung Medical Centre, Seoul, Korea, Republic of (South)
14Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
15AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium
16University of Alberta Hospital, Edmonton, Canada
17Ondokuz Mayis University, Samsun, Turkey
18Antonio e Biagio e Cesare Arrigo Hospital, Alessandria, Italy
19Rambam Medical Center, Haifa, Israel
20Faculty of Medicine Technion, Haifa, Israel
21Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
22Hospital dos Capuchos (CHLC), Lisboa, Portugal
23Wroclaw Medical University, Wroclaw, Poland
24Città della Salute e della Scienza, Torino, Italy
25Ospedale San Gerardo Monza, Monza, Italy
26Ospedale Policlinico San Martino, Genoa, Italy
27Ústav Hematologie a Krevní Transfuze, Prague, Czech Republic
28Amsterdam UMC, Location VUMC, Amsterdam, Netherlands
29Celgene Corporation, Summit, NJ
30Weill Cornell Medicine, New York, NY
31New York Presbyterian Hospital, New York, NY

Ilaria Iacobucci, PhD1, Manja Meggendorfer, PhD2, Niroshan Nadarajah2*, Stanley Pounds, PhD3*, Lei Shi, PhD3*, Chunxu Qu, PhD1*, Constance Baer, PhD2, Claudia Haferlach, MD2, Wolfgang Kern, MD2,4, Charles G. Mullighan, MBBS, MD 1 and Torsten Haferlach, MD2

1Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
2MLL Munich Leukemia Laboratory, Munich, Germany
3Biostatistics, St. Jude Children's Research Hospital, Memphis, TN
4Munich Leukemia Laboratory, Munich, Germany

Erica B. Esrick, MD1, Maureen Achebe, MD, MPH2, Myriam Armant, PhD3*, Pablo Bartolucci, MD, PhD4*, Marioara Felicia Ciuculescu, MD5*, Heather Daley6*, Colleen Dansereau, MSN, RN, CPN7*, Giuseppe Di Caprio, PhD8*, Bronner Goncalves, MD, PhD9*, Nicolas Hebert10,11*, Matthew M Heeney, MD12, John M. Higgins, MD, PhD13*, Leslie E. Lehmann, MD14, John P Manis, MD15, Olivier Negre, PhD16*, Sarah Nikiforow, MD, PhD17, Ethan Schonbrun, PhD18*, David K. Wood, PhD19* and David A. Williams, MD20

1Children's Hospital Boston, Boston, MA
2Division of Hematology, Brigham and Women's Hospital/ Harvard Medical School, Boston, MA
3TransLab, Boston Children's Hospital, Harvard Medical School, Boston, MA
4Service de Médecine Interne, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris 12, Créteil, France
5Gene Therapy for Rare Diseases, Boston Children’s Hospital, Boston
6Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
7Gene Therapy Program, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA
8Center for Systems Biology, Massachusetts General Hospital/ Harvard Medical School, Boston, MA
9Centers for Systems Biology, Massachusetts General Hospital/ Harvard Medical School, Boston, MA
10Université Paris-Est Créteil, Créteil, France
11INSERM-U955, EFS, Institut Mondor, Université Paris-Est Créteil, Team 2 Transfusion et maladies du globule rouge, Laboratoire d´Excellence GR-Ex, Créteil, France
12Division of Pediatric Hematology/Oncology, Boston Children's Hospital/ Harvard Medical School, Boston, MA
13Department of Systems Biology, Harvard Medical School, Boston
14Division of Pediatric Hematology/Oncology/Stem Cell Transplant Program, Dana-Farber/Boston Children’s Cancer & Blood Disorders Center, Boston, MA
15Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA
16bluebird bio, inc., Cambridge, MA
17Cell Manipulation Core Facilities, Dana-Farber Cancer Institute, Boston, MA
18Center for Systems Biology, Massachusetts General Hospital, Boston
19Biomedical Engineering, University of Minnesota, Minneapolis, MN
20Division of Hematology/Oncology, Dana-Farber/Boston Children’s Cancer & Blood Disorders Center, Boston, MA

Saad Z. Usmani, MD, MBBS1, Hang Quach, MD2, María-Victoria Mateos3, Ola Landgren, MD, PhD4, Xavier Leleu, MD, PhD5, David S. Siegel6, Katja Weisel7*, Hui Yang8*, Zandra K. Klippel, MD8, Anita Zahlten-Kumeli8 and Meletios A. Dimopoulos, MD9

1Atrium Health, Charlotte, NC
2St. Vincent's Hospital, Melbourne, Australia
3University Hospital Salamanca/IBSAL, Salamanca, Spain
4Memorial Sloan Kettering Cancer Center, New York, NY
5Hopital Claude Huriez, Lille, France
6John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
7Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
8Amgen, Inc., Thousand Oaks, CA
9National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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