-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

631.P1.23 631. Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy: Poster I

Program: Oral and Poster Abstracts
Type: Poster
Saturday, December 1, 2018: 6:15 PM-8:15 PM
Hall GH (San Diego Convention Center)

Jianbo He, MD1, Sahee Park2*, Soo Young Choi2*, David Crossman3*, Bin Zhang, PhD4*, Puneet Agarwal, PhD1*, Andrew Zhang1*, Su Chu, MD1*, Dong-Wook Kim, MD, PhD2 and Ravi Bhatia, MD1

1Division of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
2Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea, Republic of (South)
3Heflin Center for Genomic Sciences, University of Alabama at Birmingham, Birmingham, AL
4Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA

Barbara Peter1,2*, Gregor Eisenwort1,2*, Alexandra Keller1,2*, Karin Bauer1,2*, Daniela Berger2*, Irina Sadovnik1,2*, Gabriele Stefanzl2*, Gregor Hoermann1,3,4, Dominik Wolf5,6, Zdenek Racil7,8*, Jiří Mayer7,8, Johannes Zuber9*, Wolfgang R. Sperr1,2*, Georg E. Winter10*, Michael Willmann1,11*, Thomas Rülicke1,12* and Peter Valent1,2

1Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria
2Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
3Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
4MLL Munich Leukemia Laboratory, Munich, Germany
5Department of Hematology and Oncology, Innsbruck Medical University, Innsbruck, Austria
6Department of Hematology, Oncology and Rheumatology, Center of Integrated Oncology Cologne Bonn, University Hospital of Bonn, Bonn, Germany
7Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
8Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic
9Research Institute of Molecular Pathology (IMP), Vienna, Austria
10CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
11Department of Companion Animals and Horses, Clinic for Internal Medicine and Infectious Diseases, University of Veterinary Medicine Vienna, Vienna, Austria
12Institute of Laboratory Animal Science, University of Veterinary Medicine Vienna, Vienna, Austria

Hidenori Kasahara, MD, PhD1*, Daiki Karigane, MD, PhD2*, Rie Yamazaki, MD1*, Shinya Fujita, MD1*, Kouhei Shirosita, MD1*, Masatoshi Sakurai, MD1*, Yuya Koda, MD1*, Taku Kikuchi, MD1*, Jun Kato, MD1*, Takayuki Shimizu, MD1*, Takehiko Mori, MD, PhD1*, Yoko Yatabe3*, Tomoko Arai3*, Mitsuru Murata, MD, PhD3, Hiroshi Kobayashi, MD, PhD4*, Keiyo Takubo, MD, PhD4* and Shinichiro Okamoto, MD, PhD5

1Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
2Cancer institute, Stanford University, Stanford, CA
3Keio University School of Medicine, Tokyo, Japan
4Department of Stem Cell Biology, National Center for Global Health and Medicine Research Institute, Tokyo, Japan
5Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

Lin Tong1*, Na Xu, PhD1*, Xuan Zhou, PhD2*, Jixian Huang3*, Wu wan-Er1*, Chen Chen1*, Liu Liang1*, Qifa Liu, MD1 and Liu Xiaoli, MD4*

1Nanfang Hospital Southern Medical University, Guangzhou, China
2Nanfang Hospital Southern University, Guangzhou, China
3Department of Hematology,Nanfang Hospital,Southern Medical University, Guangzhou, China
4Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Yotaro Ochi, MD1,2*, Kenichi Yoshida, MD, PhD3*, Ying-Jung Huang4*, Ming-Chung Kuo5,6*, Yusuke Shiozawa, M.D., Ph.D.3*, Yasuhito Nannya, MD, PhD3, Yuichi Shiraishi, PhD7*, Ai Okada8*, Kenichi Chiba, PhD7*, Hiroko Tanaka, BA7*, Satoru Miyano, PhD7*, Akifumi Takaori-Kondo, MD, PhD2, Lee-Yung Shih, MD6,9 and Seishi Ogawa, MD, PhD10

1Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kobe, HYO, Japan
2Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
3Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
4Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan
5Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
6Chang Gung University, Taoyuan, Taiwan
7Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
8Laboratory of DNA Information Science, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
9Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan
10Department of Pathology and Tumor Biology, Kyoto University, Sakyoku, Japan

Manuela Mancini, PhD1*, Sara De Santis1*, Cecilia Monaldi1*, Luana Bavaro2*, Margherita Martelli2*, Fausto Castagnetti3, Gabriele Gugliotta, MD, PhD4, Gianantonio Rosti4*, Maria Chiara Fontana, MSc5*, Elisa Dan6*, Barbara Sinigaglia6*, Alessandra Iurlo7*, Nicola Orofino8*, Elisabetta Abruzzese9, Marzia Salvucci10*, Patrizia Pregno11*, Antonella Gozzini12*, Monica Crugnola, MD13*, Francesco Albano, MD14*, Massimiliano Bonifacio15*, Elisabetta Calistri, MD16*, Mario Tiribelli17*, Gianni Binotto, MD18*, Annalisa Imovilli19*, Elena Trabacchi, MD20*, Sara Galimberti21*, Claudia Baratè22*, Elena Tenti23*, Michele Baccarani, MD24, Giovanni Martinelli25*, Michele Cavo, MD26* and Simona Soverini, PhD27

1Department of Experimental Diagnostic and Specialty Medicine - DIMES Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy
2Hematology/Oncology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy
3Institute of Hematology "L. e A. Seràgnoli", DIMES, University of Bologna, Bologna, Italy
4Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy
5Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
6Department of Experimental, Diagnostic and Specialty Medicine - DIMES, Institute of Hematology "L. and A. Seràgnoli", Bologna, Italy
7Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
8UO Ematologia, Fondazione IRCCS Ca' Granda - Ospedale Policlinico, Milano, Milano, Italy
9Hematology Unit, S. Eugenio Hospital, Roma, Italy
10Azienda Azienda USL di Romagna, Ravenna, Ravenna, Italy
11Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy
12Divisione di Ematologia-Policlinico Careggi di Firenze, Firenze, ITA
13Department of Medicine and Surgery, University of Parma, Parma, Italy
14University of Bari, Department of Emergency and Organ Transplantation (D.E.T.O.), Hematology Section, Bari, Italy
15Department of Medicine, Section of Hematology, Stem Cell Research Lab, University of Verona, Verona, Italy
16UO Hematology, Ca Foncello Hospital, Treviso, Italy
17Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
18Hematology and Clinical Immunology, Department of Medicine, Padua School of Medicine, Padova, Italy
19Hematology Unit, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, Italy
20Hematology and BMT Unit, Department of Hematology and Oncology, Guglielmo da Saliceto Hospital, Piacenza, Italy
21Hematology Department, University of Pisa, Pisa, Italy
22UO Ematologia - AOU Pisana - Pisa, Pisa, Italy
23)Department of Experimental, Diagnostic and Specialty Medicine - DIMES, Institute of Hematology "L. and A. Seràgnoli", Bologna, Italy
24Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Institute of Hematology and Medical Oncology "L. & A. Seràgnoli", Bologna, Italy
25Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, Meldola, Italy
26Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Bologna, Italy
27Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Castel Maggiore, Bologna, Italy

Jeevisha Bajaj, PhD1, James P. Scott-Browne, PhD2*, Kyle Spinler, BS, DPhil3 and Tannishtha Reya, PhD4

1Pharmacology, University of California, San Diego, La Jolla, CA
2Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, CA
3Pharmacology, University of California San Diego, San Diego, CA
4University of California, San Diego, La Jolla, CA

*signifies non-member of ASH