-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

635.O1.6 635. Myeloproliferative Syndromes: Basic Science: Mechanisms of Development and Progression

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
HSCs, Diseases, platelets, red blood cells, Biological Processes, white blood cells, MPN, Cell Lineage, Polycythemia vera, thrombocythemia, Myeloid Malignancies, hematopoiesis, pathogenesis
Saturday, December 1, 2018: 9:30 AM-11:00 AM
Room 7B (San Diego Convention Center)
Moderators:
Edwin Chen, PhD, University of Leeds and Kazuya Shimoda, MD, PhD, Miyazaki University
Disclosures:
No relevant conflicts of interest to declare.
9:30 AM

Kotaro Shide, MD, PhD1, Takuro Kameda, MD1, Ayako Kamiunten, MD1*, Masaaki Sekine, MD1*, Yoshinori Ozono, MD1*, Takako Yokomizo, PhD2*, Keiichi Akizuki, MD1*, Yuki Tahira, MD1*, Yoko Kubuki, MD, PhD1*, Tomonori Hidaka, MD1*, Goro Sashida, MD, PhD2 and Kazuya Shimoda, MD, PhD1

1Department of Hematology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
2Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University, Kumamoto City, Japan

9:45 AM

Claudia Korn, PhD1*, Justyna Rak, PhD1*, Andrés García-García, PhD1*, Claire Fielding1*, Reema Khorshed, PhD2*, Sara González-Antón2*, Juan Li, PhD1*, Ruggiero Norfo, PhD3*, E Joanna Baxter, PhD1*, Thomas McKerrell, MD, PhD1*, Thomas Roberts1*, Hesham Eldaly, MD1*, Anna L Godfrey, PhD1*, Aracely Castillo-Venzor1*, Anjali Kusumbe, PhD3*, Adam J. Mead, MD, PhD3, Anthony R Green1, David Kent, PhD1*, Cristina Lo Celso, PhD2* and Simon Mendez-Ferrer, PhD1

1University of Cambridge, Cambridge, United Kingdom
2Imperial College, London, United Kingdom
3University of Oxford, Oxford, United Kingdom

10:00 AM

Samuel A Stoner, BS1,2, Ming Yan, PhD1*, Katherine Liu2*, Takahiro Shima, MD, PhD3*, Huan-You Wang, MD, PhD2*, Kei-Ichiro Arimoto, PhD2*, Rafael Bejar, MD, PhD4, Catriona Jamieson, MD, PhD5, Kun-Liang Guan, PhD6* and Dong-Er Zhang, PhD2

1University of California, San Diego, La Jolla, CA
2Moores Cancer Center, University of California, San Diego, La Jolla, CA
3Department of Pathology & Division of Biological Sciences, University of California, San Diego, La Jolla, CA
4University of California San Diego, Moores Cancer Center, La Jolla, CA
5Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA
6Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA

10:15 AM

Daisuke Shinoda, MD1,2*, Yaeko Nakajima-Takagi, PhD1,3*, Motohiko Oshima, PhD1,3*, Atsunori Saraya1*, Hironori Harada, MD, PhD4, Haruhiko Koseki, PhD5*, Kazuya Shimoda, MD, PhD6, Goro Sashida, MD, PhD7 and Atsushi Iwama, MD, PhD1,3

1Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
2Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, Tokyo University, Chiba, Japan
3Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, Tokyo University, Tokyo, Japan
4Laboratory of Oncology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
5Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
6Department of Hematology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
7Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University, Kumamoto City, Japan

10:30 AM

Xiaoli Wang, PhD1, Cing Siang Hu2*, Joseph Tripodi2*, Vesna Najfeld, PhD3, Bruce Petersen, MD2, Raajit K. Rampal, MD, PhD4, Noushin Farnoud5*, Christopher Famulare, MS5*, John Mascarenhas, MD6 and Ronald Hoffman, MD7

1Division of Hematology/Medical Oncology/Pathology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai; Myeloproliferative Neoplasm Research Consortium (MPN-RC), Rego Park, NY
2Division of Hematology/Medical Oncology/Pathology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
3Division of Hematology/Medical Oncology/Pathology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai; Myeloproliferative Neoplasm Research Consortium (MPN-RC), New York, NY
4Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center; Myeloproliferative Neoplasm Research Consortium (MPN-RC), New York, NY
5Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
6Icahn School of Medicine at Mount Sinai, New York, NY
7Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

10:45 AM

Linda Resar, MD1, Donna Marie Williams, PhD2*, Lingling Xian, MD, PhD2*, Wenyan Lu, PhD2*, Briyana Chisholm, BS2*, Li Luo, PhD2*, Zhizhuang Joe Zhao, PhD3, Ophelia Rogers2*, Jerry L. Spivak, MD2 and Alison R. Moliterno, MD2

1Division of Hematology, Departments of Medicine, Oncology & Pathology, Johns Hopkins University SOM, Baltimore, MD
2Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
3Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

*signifies non-member of ASH