-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

632.O2.6 632. Chronic Myeloid Leukemia: Therapy: First Line Trials and Prognostic Factors of Treatment-Free Remission

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Diseases, CML, Myeloid Malignancies
Sunday, December 2, 2018: 4:30 PM-6:00 PM
Room 6E (San Diego Convention Center)
Moderators:
James K McCloskey, MD, Hackensack University Medical Center and Philipp le Coutre, MD, Charite Humboldt Universität
Disclosures:
McCloskey: Celgene Pharmaceuticals: Honoraria, Speakers Bureau; Jazz Pharmaceuticals: Consultancy, Speakers Bureau; Jazz Pharmaceuticals: Consultancy, Speakers Bureau; Takeda Pharmaceuticals: Consultancy, Speakers Bureau; Amgen Pharmaceuticals: Speakers Bureau; Jazz Pharmaceuticals: Consultancy, Speakers Bureau; Celgene Pharmaceuticals: Honoraria, Speakers Bureau; COTA: Equity Ownership; Pfizer: Consultancy; Takeda Pharmaceuticals: Consultancy, Speakers Bureau; Amgen Pharmaceuticals: Speakers Bureau; Jazz Pharmaceuticals: Consultancy, Speakers Bureau; Takeda Pharmaceuticals: Consultancy, Speakers Bureau; COTA: Equity Ownership; COTA: Equity Ownership; Pfizer: Consultancy; Pfizer: Consultancy; Amgen Pharmaceuticals: Speakers Bureau; Pfizer: Consultancy; Takeda Pharmaceuticals: Consultancy, Speakers Bureau; Celgene Pharmaceuticals: Honoraria, Speakers Bureau.
4:30 PM

Stephen O'Brien, MBBS, BSc, PhD, MRCPath, MRCP1*, Leanne Cork, BSc1*, Valeria Bandeira, MD2*, Ruth Bescoby, MSc1*, Letizia Foroni, MD, PhD3*, Lynn Alaily, MSc, RN, NDN, MICR1*, Wendy Osborne, MBBS1*, Helen Bell-Gorrod, BSc4*, Nicholas Latimer, PhD5*, Jane Apperley, MB ChB MD6, Corinne Hedgley, BSc (Hons)1*, Richard Syzdlo, PhD7*, Jennifer Byrne, MB, ChB, MRCP, MRCPath, MD8*, Christopher Pocock, MD, PhD 9, Bernard Ramsahoye, MB, ChB, PhD, FRCPath, MRCP10*, Thomas Zwingers, BSc2*, James Wason, PhD1*, Mhairi Copland, PhD, MBBChir, FRCP, FRCPath11 and Richard Clark, MBBS, MRCP, MRCPath, MD12*

1Clinical Trials Unit, Newcastle University, Newcastle Upon Tyne, United Kingdom
2CROS NT, Berkshire, United Kingdom
3Centre for Haematology, Imperial College London at Hammersmith Hospital, London, United Kingdom
4Health Economics and Decison Modelling, Sheffield University, Sheffield, United Kingdom
5Health Economics and Decision Science, University of Sheffield, Sheffield, United Kingdom
6Centre for Haematology, Department of Medicine, Imperial College London, London, United Kingdom
7South Kensington Campus, Imperial Colege London, London, United Kingdom
8Centre for Clinical Haematology, Nottingham University Hospitals Trust, Nottingham, GBR
9East Kent Hospitals, Canterbury, United Kingdom
10Western General Hospital, Edinburgh, GBR
11Cancer Division, Gartnavel General Hospital, Glasgow, United Kingdom
12Royal Liverpool University Hospitals NHS Trust, Liverpool, GBR

4:45 PM

Gabriele Gugliotta, MD, PhD1, Fausto Castagnetti, MD, PhD2, Massimo Breccia, MD3*, Alessandra Iurlo4*, Mariella D'Adda5*, Fabio Stagno, MD, PhD6, Luciano Levato7*, Bruno Martino, MD8*, Francesca Lunghi9*, Mario Tiribelli10*, Giovanna Rege Cambrin, MD11*, Elisabetta Abruzzese, MD12, Serena Rupoli, MD13*, Antonella Gozzini14*, Patrizia Pregno15*, Marzia Salvucci, MD16*, Elena Trabacchi, MD17*, Giovanni Caocci, MD18*, Anna Rita Scortechini, MD19*, Luigia Luciano, MD20, Giuseppe Tagariello21*, Massimiliano Bonifacio22*, Simona Soverini, PhD23, Robin Foà, MD24, Giovanni Martinelli, MD25, Michele Cavo, MD2*, Fabrizio Pane26, Giuseppe Saglio27, Michele Baccarani, MD1 and Gianantonio Rosti1*

1Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy
2Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Bologna, Italy
3Division of Cellular Biotechnologies and Hematology, University "Sapienza", Roma, Italy
4Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
5Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
6Hematology Unit, Hematology Section, Biomedical Sciences, Trecastagni, Catania, Italy
7Department Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
8Hematology Department, Grande Ospedale Metropolitano-G.O.M. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
9Haematology and Bone Marrow Transplant Unit, San Raffaele Scientific Institute IRCCS, Milano, Italy
10Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
11University of Turin, ORBASSANO TORINO, ITA
12Haematology Unit, S. Eugenio Hospital, Rome, Italy
13Hematology Unit, AOU- Ospedali Riuniti Umberto I, Ancona, Italy
14Divisione di Ematologia-Policlinico Careggi di Firenze, Firenze, ITA
15Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy
16Hematology Unit, S. Maria delle Croci Hospital, Ravenna, Italy
17Hematology and BMT Unit, Department of Hematology and Oncology, Guglielmo da Saliceto Hospital, Piacenza, Italy
18Department of Medical Sciences and Public Health, University of Cagliari, "A.Businco" Hospital, Cagliari, Italy
19Hematology Unit, Ospedali Riuniti University Hospital, Ancona, Italy
20Hematology Unit, Federico II University of Naples, Napoli, ITA
21Regional General Hospital, Castelfranco Veneto, ITA
22Department of Medicine, Section of Haematology, University of Verona, Verona, Italy
23Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Castel Maggiore, Bologna, Italy
24Hematology, Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy
25Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRST IRCCS, Meldola, Italy
26Hematology Unit, Federico II University of Naples, Napoli, Italy
27Hematology Division, Ospedale Mauriziano, University of Turin, Torino, Italy

5:00 PM

David T Yeung, PhD, BSc, FRACP, FRCPA, MBBS1,2, Andrew P. Grigg, MBBS, FRACP, FRCPA, MD3*, Naranie Shanmuganathan, MBBS4,5, Ilona Cunningham, MBBS FRACP FRCPA6, Jake Shortt, FRACP, FRCPA, PhD7, Philip Rowling, MBBS FRACP FRCPA8*, John Reynolds, PhD9*, Rachel Cushion10*, Rosemary Anne Harrup, MD11*, David M Ross12*, David Kipp, MBBS, FRCPA, FRACP13, Anthony K Mills, FRACP, FRCPA, MBBS14, Christopher K Arthur15, Anthony P Schwarer, MD, MBBS (Hons), FRACP, FRCPA16, Kathryn Jackson, MBBS FRACP FRCPA17*, Nicholas Viiala, MBBS FRACP FRCPA18*, Robert Weinkove, MD19, Agnes S. M. Yong, MD, PhD1, Deborah L White, PhD1, Susan Branford, PhD20,21, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA1 and On Behalf of the ALLG22*

1Cancer Theme, South Australian Health and Medical Research Institute, Adelaide, Australia
2Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, Australia
3Department of Clinical Haematology, Austin Hospital, VIC, Australia
4Department of Haematology, Royal Adelaide Hospital and SA Pathology, Brompton, SA, Australia
5Centre for Cancer Biology, SA Pathology, Adelaide, Australia
6Haematology, Concord Hospital, Concord, Australia
7Peter MacCallum Cancer Centre, Clayton, AUS
8Haematology, Calvary Mater Newcastle Hospital, Waratah, Australia
9Biostatistics Consulting Platform, Alfred Health and Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, Australia
10Australasian Leukaemia and Lymphoma Group, Richmond, Australia
11Department of Haematology, Royal Hobart Hospital, Hobart, AUS
12Department of Haematology, Flinders Medical Centre, Bedford Park, Australia
13Andrew Love Cancer Centre, University Hospital Geelong, GEELONG, Australia
14Department of Haematology, Princess Alexandra Hospital, Brisbane, Australia
15Department of Haematology, Royal North Shore Hospital, St Leonards, NSW, Australia
16Department of Haematology, The Alfred Hospital and Box Hill Hospital, Melbourne, Australia
17Nambour General Hospital, Birtinya, Australia
18Liverpool Hospital, Sydney, Australia
19Capital & Coast District Health Board, Wellington, New Zealand
20Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, Australia
21Genetic and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia
22Australasian Leukaemia and Lymphoma Group, Melbourne, Australia

5:15 PM

Andreas Hochhaus, MD1, Susanne Saussele, MD2*, Gabriela M Baerlocher3, Tim H Brümmendorf, MD4, Andreas Burchert, MD5, Paul La Rosée, MD6*, Joerg Hasford, MD7*, Rüdiger Hehlmann, MD8, Dominik Heim, MD9, Stefan W Krause, MD10*, Philipp le Coutre, MD11, Dietger Niederwieser, MD12, Jiří Mayer13, Thoralf Lange, MD14*, Mathias Haenel, MD15*, Frank Stegelmann, MD16*, Arthur Gil, MPH7*, Thomas Ernst17, Christian Fabisch, PhD1* and Markus Pfirrmann, PhD7*

1Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany
2Universitätsmedizin Mannheim, Mannheim, Germany
3Department of Hematology, Inselspital Bern, University Hospital, University of Bern, Bern, Switzerland
4Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, University Hospital RWTH Aachen University, Aachen, Germany
5Dep. of Internal Medicine, Hematologgy, Oncology and Immunology, Philips Univ. Marburg, Marburg, Hessen, Germany
6Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Germany
7IBE, Ludwig-Maximilians-Universität, München, Germany
8ELN Foundation, Weinheim, Germany
9Hematology, University Hospital Basel, Basel, Switzerland
10Medizinische Klinik V, Universitätsklinikum Erlangen, Erlangen, Germany
11Hematology and Oncology, Charite Humboldt Universität, Berlin, Berlin, Germany
12Department of Hematology and Oncology, University Hospital Leipzig, Leipzig, Germany
13Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
14Asklepios Klinikum Weissenfels, Weissenfels, Germany
15Department of Hematology, Oncology and Stem Cell Transplantation, Klinikum Chemnitz GmbH, Chemnitz, Germany
16Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
17Klinik für Innere Medizin II, Abt. Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany

5:30 PM

Silvia Mori, PhD1*, Philipp le Coutre, MD2, Elisabetta Abruzzese3, Bruno Martino, MD4*, Ester Pungolino5*, Chiara Elena, MD6*, Micaela Bergamaschi, MD7*, Sarit Assouline, MD8, Eros Di Bona, MD9*, Antonella Gozzini, MD10*, Marcio Andrade, MD11*, Fabio Stagno, MD, PhD12, Alessandra Iurlo13*, Dong-Wook Kim, MD, PhD14, Michela Luciani, RN, PhD15*, Alessandra Pirola, M.Sc.16*, Maria Luisa Bonanomi17*, Patrizia Crivori, PhD17*, Rocco Piazza, MD, PhD15* and Carlo Gambacorti-Passerini, MD1,18

1School of Medicine and Surgery, University of Milano Bicocca, Monza, MB, Italy
2Hematology and Oncology, Charite Humboldt Universität, Berlin, Berlin, Germany
3Hematology, S.Eugenio Hospital, Roma, Italy
4Hematology, "Bianchi Melacrino Morelli", Reggio Calabria, ITA
5Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
6Department of Hematology Oncology, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
7Hematology Clinic, Policlinico San Martino-IST, Genova, Italy
8McGill University Jewish General Hospital, Montreal, QC, Canada
9Ospedale San Bortolo, UO Hematology, Vicenza, Italy
10SC Terapie Cellulari e Medicina Trasfusionale, AOU Careggi, Florence, Italy
11Hospital Universitario Miguel Servet, Zaragoza, Spain
12Hematology Unit, Hematology Section, Biomedical Sciences, Trecastagni, Catania, Italy
13Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
14Department of Hematology, Seoul St. Mary's Hospital The Catholic University of Korea, Seoul, South Korea
15School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
16GalSeq s.r.l, Bresso (MI), Italy
17Clioss s.r.l, Nerviano (MI), Italy
18Hematology Unit, ASST-Monza, San Gerardo Hospital, Monza, Italy

5:45 PM

Franck Emmanuel Nicolini, MD, PhD1,2,3, Stephanie Dulucq, PhD3,4*, Joelle Guilhot, PhD3,5, Gabriel Etienne, MD, PhD3,6* and Francois-Xavier Mahon, MD, PhD3,7

1INSERM U590, CRCL, Lyon, France
2Hematology, Centre Leon Berard, Lyon, France
3French group of CML (Fi-LMC), Pessac, France
4Laboratory of Hematology, Hopital Haut Leveque, Pessac, France
5Inserm CIC 1402, CHU de Poitiers, Poitiers, France
6Hematology Department, Institut Bergonié, Bordeaux, France
7Hematology Department, Institut Bergonie, Bordeaux, France

*signifies non-member of ASH