-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

632.O1.6 632. Chronic Myeloid Leukemia: Therapy: Epidemiology, Prognosis, and Real Life Care

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Diseases, CML, Myeloid Malignancies
Saturday, December 1, 2018: 7:30 AM-9:00 AM
Seaport Ballroom A (Manchester Grand Hyatt San Diego)
Moderators:
Kendra L. Sweet, MD, Moffitt Cancer Center and Delphine Rea, MD,
Disclosures:
Sweet: Celgene: Speakers Bureau; Bristol Myers Squibb: Honoraria; Incyte: Research Funding; Novartis: Consultancy, Honoraria, Speakers Bureau; Astellas: Consultancy; Pfizer: Consultancy, Honoraria; Jazz Pharmaceuticals: Honoraria, Speakers Bureau; Agios: Consultancy.
7:30 AM

Elisabetta Abruzzese, MD1, Chiara Elena, MD2*, Fausto Castagnetti, MD, PhD3, Carlo Gambacorti-Passerini, MD4, Mario Annunziata5*, Luigia Luciano, MD6, Giorgina Specchia, MD7, Alessandra Iurlo8*, Isabella Capodanno9*, Patrizia Pregno10*, Antonella Gozzini, MD11*, Simona Sica, MD12*, Mario Tiribelli13*, Sara Galimberti14*, Monica Bocchia, MD, PhD15*, Clementina Caracciolo, MD16*, Giovanna Rege Cambrin, MD17*, Micaela Bergamaschi, MD18*, Anna Rita Scortechini, MD19*, Alessandro Rambaldi, MD20, Diamante Turri, MD21*, Claudio Fozza, MD22*, Mariella D'adda, MD23*, Lucia Mastrullo, MD24*, Marzia Salvucci, MD25*, Caterina Musolino, MD26*, Gianluca Gaidano, MD, PhD27, Filippo Gherlinzoni, MD28*, Anna d'Emilio, MD29*, Paola Fazi, MD30* and Michele Baccarani, MD31

1S. Eugenio Hospital, Tor Vergata University, Rome, Italy
2Hematology, IRCSS S. Matteo, Pavia, Jamaica
3Institute of Hematology "L. e A. Seràgnoli", DIMES, University of Bologna, Bologna, Italy
4School of Medicine and Surgery, University of Milano Bicocca, Monza, MB, Italy
5Hematology, Ospedale Cardarelli, Napoli, Italy
6Hematology Unit, Federico II University of Naples, Napoli, ITA
7Hematology - Dept. of Emergency and Organ Transplantation, University of Bari, Bari, Italy
8Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
9Hematology Department, Arcispedale Santa Maria Nuova - IRCCS Reggio, Reggio Emilia, Italy
10AZ OSP CITTA' DELLA SALUTE E SCIENZA TORINO, University of Torino, TORINO, Italy
11SC Terapie Cellulari e Medicina Trasfusionale, AOU Careggi, Florence, Italy
12Hematology Department, Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Italy
13Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
14Hematology Department, University of Pisa, Pisa, Italy
15Chair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, Siena, Italy
16Hematology A.U. Paolo Giaccone, Palermo, Italy
17University of Turin, ORBASSANO TORINO, ITA
18Clinical Hematology Unit, IRCCS AOU S.Martino-IST, Genova, Italy
19Hematology Unit, A.O.U. Ospedali Riuniti, Ancona, Italy
20Hematology and Bone Marrow Transplantation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
21Hematology, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy
22Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
23Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
24Ospedale San Gennaro, NAPOLI, ITA
25Hematology Unit, S. Maria delle Croci Hospital, Ravenna, Italy
26Divisione di Ematologia - Policlinico Universitario, Messina, Italy
27Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
28Division of Hematology, Ca’ Foncello Hospital, Treviso, ITA
29ULSS Ospedale S. Bortolo, Vicenza, Italy
30GIMEMA Foundation, Rome, Italy
31Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy

7:45 AM

Fausto Castagnetti, MD, PhD1, Gabriele Gugliotta, MD, PhD2, Massimo Breccia, MD3*, Fabio Stagno, MD, PhD4, Giorgina Specchia, MD5, Luciano Levato6*, Bruno Martino, MD7*, Mariella D'Adda8*, Elisabetta Abruzzese9, Patrizia Pregno10*, Mario Tiribelli11*, Alessandra Iurlo12*, Tamara Intermesoli, MD13*, Anna Rita Scortechini, MD14*, Francesco Cavazzini, MD15*, Carmen Fava16, Massimiliano Bonifacio17*, Marzia Salvucci, MD18*, Monica Bocchia, MD, PhD19*, Giovanni Caocci, MD20*, Antonella Gozzini, MD21*, Micaela Bergamaschi, MD22*, Simona Soverini, PhD23, Robin Foà, MD24, Giovanni Martinelli25, Michele Cavo, MD1*, Giuseppe Saglio26, Fabrizio Pane27, Michele Baccarani, MD2 and Gianantonio Rosti2*

1Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Bologna, Italy
2Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy
3Division of Cellular Biotechnologies and Hematology, University "Sapienza", Roma, Italy
4Hematology Unit, Hematology Section, Biomedical Sciences, Trecastagni, Catania, Italy
5Hematology - Dept. of Emergency and Organ Transplantation, University of Bari, Bari, Italy
6Department Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
7Hematology Department, Grande Ospedale Metropolitano-G.O.M. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
8Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
9Hematology Unit, S. Eugenio Hospital, Roma, Italy
10Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy
11Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
12Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
13Hematology and Bone Marrow Transplantation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
14Hematology Unit, A.O.U. Ospedali Riuniti, Ancona, Italy
15Division of Hematology, Department of Medical Sciences, University of Ferrara, Azienda Ospedaliera-Universitaria, Arcispedale S. Anna, Ferrara, Italy
16Department of Clinical and Biological Science, University of Turin, Orbassano, Italy
17Department of Medicine, Section of Haematology, University of Verona, Verona, Italy
18Hematology Unit, S. Maria delle Croci Hospital, Ravenna, Italy
19Chair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, Siena, Italy
20Department of Medical Sciences and Public Health, University of Cagliari, "A.Businco" Hospital, Cagliari, Italy
21SC Terapie Cellulari e Medicina Trasfusionale, AOU Careggi, Florence, Italy
22Clinical Hematology Unit, IRCCS AOU S.Martino-IST, Genova, Italy
23Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Castel Maggiore, Bologna, Italy
24Hematology, Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy
25Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, Meldola, Italy
26Hematology Division, Ospedale Mauriziano, University of Turin, Torino, Italy
27Hematology Unit, Federico II University of Naples, Napoli, Italy

8:00 AM

Giorgina Specchia, MD1, Patrizia Pregno2*, Maura Nicolosi, MD3*, Fausto Castagnetti4, Bruno Martino, MD5*, Massimo Breccia, MD6*, Massimiliano Bonifacio7*, Fabio Stagno, MD, PhD8, Antonella Gozzini9*, Mario Tiribelli10*, Micaela Bergamaschi, MD11*, Michele Pizzuti, MD12*, Giovanni Caocci, MD13*, Luigia Luciano, MD14, Pietro Leoni, PhD15*, Anna Guella, MD16*, Franca Falzetti, MD17*, Roberto Di Lorenzo, MD18*, Fabio Saccona19*, Chiara Monagheddu, MD19*, Francesco Albano, MD20*, Fabrizio Pane21, Giovannino Ciccone, MD19*, Michele Baccarani, MD22 and Giuseppe Saglio23,24

1Hematology - Dept. of Emergency and Organ Transplantation, University of Bari, Bari, Italy
2Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy
3Az Osp Citta' della Salute e della Scienza, University of Torino, Torino, Italy
4Institute of Hematology "L. e A. Seràgnoli", DIMES, University of Bologna, Bologna, Italy
5Hematology Department, Grande Ospedale Metropolitano-G.O.M. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
6Division of Cellular Biotechnologies and Hematology, University "Sapienza", Roma, Italy
7Department of Medicine, Section of Haematology, University of Verona, Verona, Italy
8Hematology Unit, Hematology Section, Biomedical Sciences, Trecastagni, Catania, Italy
9Divisione di Ematologia-Policlinico Careggi di Firenze, Firenze, ITA
10Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
11Division of Hematology, University of Genoa, Opsedale policlinico San Martino, IRCCS per l'Oncologia, Dipartment of Internal Medicine, Genova, Italy
12Ematologia, Azieda Ospedaliera S. Carlo, Potenza, Italy
13Department of Medical Sciences and Public Health, University of Cagliari, "A.Businco" Hospital, Cagliari, Italy
14Hematology Unit, Federico II University of Naples, Napoli, ITA
15Clinica Di Ematologia Ancona University, Clinica Di Ematologia Ancona University, Torrette di Ancona, ITA
16Ematology section, Ematology section,U.O. Medicina II,Ospedale Santa Chiara, trento, Italy
17Institute of Hematology, Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy
18University of Pescara, Ematology section, ASO Spirito Pescara, Pescara, Italy
19SCDU Epidemiologia dei Tumori-CPO Piemonte, Az Osp Citta della salute e della Scienza, Turin, Italy
20Hematology - Dept. of Emergency and Organ Transplantation - University of Bari, Bari, Italy
21Hematology Unit, Federico II University of Naples, Napoli, Italy
22Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy
23Department of Clinical and Biological Sciences, University of Turin, Orbassano, Turin, Italy
24Hematology Division, Ospedale Mauriziano, University of Turin, Torino, Italy

8:15 AM

Katia B Pagnano, MD1, Carmen Fava2, Eliana C Miranda3*, Israel Bendit, MD, PhD4*, Fernanda S Seguro, MD5*, Gustavo HR Magalhaes, MD6*, Nelma D Clementino, MD6*, Monika Conchon, MD7*, Natália N Gonçalves, MD8*, Gianluca Gaidano, MD, PhD9, Monia Lunghi, MD, PhD10*, Arthur Moellmann-Coelho, MD11*, Ingrid Luise, MD12*, Micaela Bergamaschi, MD13*, Dario Ferrero, MD14*, Renato Centrone, MD15*, Patrizia Pregno16*, Laura Fogliatto17, Valentina Giai18*, Matteo Emidio Dragani, MD19*, Elena Moiraghi20*, Jaisson Bortolini, MD21*, Andrea Castelli22*, Alessandra Cuttica, MD23*, Teresa Cristina Bortolheiro, MD24*, Cristiane Pinna, MD25*, Carmino Antonio De Souza, MD, PhD3* and Giuseppe Saglio26

1INCT do Sangue Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil
2Department of Clinical and Biological Science, University of Turin, Orbassano, Italy
3Centro de Hematologia e Hemoterapia, University of Campinas, Campinas, Brazil
4Hospital das, Universidade de Sao Paulo, Sao Paulo, Brazil
5Hospital das Clinicas da Faculdade de Medicina - Hematology Department, University of Sao Paulo, São Paulo , Brazil
6Hospital das Clínicas - UFMG, Belo Horizonte, Brazil
7Hospital Santa Marcelina, Sao Paulo, Brazil
8Hospital Santa Marcelina, São Paulo, Brazil
9Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
10University of Eastern Piedmont, Novara, Italy
11Nacional Cancer Institute of Brazil, Rio de Janeiro, Brazil
12Department of Hematology, National Cancer Institute of Brazil, Rio de Janeiro, Brazil
13Hematology Clinic, Policlinico San Martino-IST, Genova, Italy
14A.O.U. Città della Salute e della Scienza, Torino, Italy
15Instituto Hemomed de Oncologia e Hematologia, Sao Paulo, Brazil
16Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy
17Serviço de Hematologia; Grupo de Pesquisa em Hematologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
18Hematology Unit, Antonio e Biagio e Cesare Arrigo Hospital, Alessandria, Italy
19Department of Clinical and Biological Sciences, University of Turin, Orbassano (TO), Italy
20Hospital Ramos Mejía, Buenos Aires, Argentina
21Centro de Pesquisas Oncologicas, Florianopolis, Brazil
22Dipartimento di Medicina e Urgenza, Ospedale degli Infermi, Ponderano, Italy
23SSD Ematologia ASLTO4, Cirie, Italy
24Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil
25Universidade Federal da Bahia, Salvador, Brazil
26Department of Clinical and Biological Sciences, University of Turin, Orbassano, Turin, Italy

8:30 AM

Juan Carlos Hernandez Boluda, MD, PhD1*, Arturo Pereira, MD, PhD2*, Irene Pastor-Galán, Medical Doctor3*, Alberto Alvarez-Larrán, MD, PhD4*, Alisa Savchuk5*, Jose Manuel Puerta6*, Jose M. Sanchez7,8*, Rosa Collado9*, Álvaro Díaz10*, Anna Angona, MD, PhD11*, Miguel Sagüés12*, Valentín García Gutiérrez, PhD13,14, Concepcion Boque, MD. PhD15*, Ignacio Gómez-Centurión, MD16*, Rolando Vallansot, MD17*, Luis Palomera, MD, PhD18*, Arantxa Mendizábal19*, Luis Felipe Casado, MD20*, Manuel Pérez-Encinas21*, Raul Perez Lopez22*, Francisca Ferrer Marin23*, Fermin Sanchez-Guijo, MD, PhD24*, Carmen Garcia-Hernandez, MD25*, Natalia de las Heras26*, Jose Luiz Lopez Lorenzo, MD27*, Francisco Cervantes, MD, PhD28 and Juan Luis Steegmann, MD, PhD29

1Hematology Department, Hospital Clínico Universitario, Valencia, Spain
2Hemotherapy and Hemostasis Department, Hospital Clínic, Barcelona, Spain
3Hematology, Hospital Clinico Universitario, Valencia, Spain
4Hematology, Hospital Clínic, Barcelona, Spain
5Hematology, Hospital Universitario La Princesa, Madrid, Spain
6Hospital Universitario Virgen de las Nieves, Granada, Spain
7Hematology, Hospital 12 de Octubre, Madrid, Spain
8Hospital Universitario 12 de Octubre, Madrid, Spain
9Hospital General Universitario, Valencia, Spain
10Hematology, Hospital La Fe, Valencia, Spain
11Hospital del Mar, Barcelona, Spain
12Hospital Dr Josep Trueta, Gerona, Spain
13Hematology, Hospital Universitario Ramón y Cajal, Madrid, Spain
14Servicio Hematologia y Hemoterapia, Hospital Universitario Ramon y Cajal, Madrid, Spain
15Institut Catala d'Oncologia, Hospitalet de Llobregat, Spain
16Hospital General Universitario Gregorio Marañón, Madrid, Spain
17Servei d´Hematologia, ICO-Tarragona, Hospital Universitari Joan XXIII, TARRAGONA, Spain
18Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
19Hospital Universitario de Alava, Vitoria, Spain
20Hospital Virgen de la Salud, Toledo, Spain
21Haematology Department, Hospital Clínico, Sanatiago De Compostela, Spain
22Servicio de Hematología, Hospital Universitario Clínico Virgen de la Arrixaca, MURCIA, Spain
23Hematology and Medical Oncology Department, Hospital Morales Meseguer, IMIB, Murcia, Spain, Murcia, Spain
24Hematology Department, Hospital Clínico Universitario de Salamanca (CAUSA/IBSAL), Salamanca, Spain
25Hospital General de Alicante, Alicante, Spain
26Complejo Asistencial Universitario de León, León, Spain
27Fundación Jiménez Díaz, Madrid, Spain
28Hematology, Hospital Clinic, Barcelona, Spain
29Hospital Universitario de la Princesa, Madrid, ESP

8:45 AM

Marie Balsat, MD1,2*, Vincent Alcazer, MD3*, Gabriel Etienne, MD, PhD2,4*, Gaelle Fossard, MD1*, Francoise Huguet, MD2,5*, Marc G. Berger, MD, PhD2,6*, Emilie Cayssials, MD2,7*, Aude Charbonnier, MD2,8*, Martine Escoffre-Barbe, MD2,9*, Hyacinthe Johnson-Ansah, MD2,10*, Viviane Dubruille, MD2,11*, Laurence Legros, MD, PhD2,12*, Lydia Roy, MD2,13*, Alain Jacques Delmer, MD2,14, Jean-Christophe Ianotto, MD, PhD2,15*, Martine Gardembas, MD2,16*, Fabrice Larosa2,17*, Stephane Courby, MD2,18*, Shanti Ame, MD2,19*, Stephane Morisset, Stat3*, Francois-Xavier Mahon, MD, PhD2,20, Delphine Rea, MD2,21 and Franck Emmanuel Nicolini, MD, PhD2,3,22

1Hematology, Centre Hospitalier Lyon Sud, Pierre Benite, France
2French group of CML (Fi-LMC), Pessac, France
3Hematology, Centre Leon Berard, Lyon, France
4Hematology Department, Institut Bergonié, Bordeaux, France
5Hematology Department, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
6Hématologie Biologique and EA 7453 CHELTER, CHU Estaing and Université Clermont Auvergne, Clermont-Ferrand, France
7CHU POITIERS, POITIERS, FRA
8Hematology department, Institut Paoli Calmettes, Marseille, France
9Service d'Hématologie Adulte, CHU de Rennes, Rennes, France
10Hematology department, CHU Caen, Caen, France
11Clinical Hematology, Nantes University Hospital, Nantes, France
12Department of Hematology, Centre Hospitalier Universitaire de Nice, Nice, France
13Hematology department, Hopital Henri Mondor, Creteil, France
14Hopital Robert Debre CHU de Reims, Reims, Cedex, France
15Institute of Oncology and Hematology, Brest, France
16Hematology department, University Hospital Angers, Angers, France
17HOPITAL JEAN MINJOZ, BESANCON CEDEX, FRA
18Hematology department, CHU Grenoble, Grenoble, France
19Hematology department, Hopital Civil , CHU Strasbourg, Strasbourg, France
20Hematology Department, Institut Bergonie, Bordeaux, France
21Adult Hematology department, Hôpital Saint-Louis, Paris, France
22INSERM U590, CRCL, Lyon, France

*signifies non-member of ASH