-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

631.O1.6 631. Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy: CML Stem Cells And Their Environment

Program: Oral and Poster Abstracts
Type: Oral
Monday, December 3, 2018: 4:30 PM-6:00 PM
Room 7B (San Diego Convention Center)
Moderators:
Susan Branford, PhD, SA Pathology and Angela G. Fleischman, MD, PhD, University of California, Irvine
Disclosures:
Branford: Novartis: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; BMS: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Cepheid: Honoraria; Qiagen: Honoraria, Membership on an entity's Board of Directors or advisory committees.
4:30 PM

Andrew Wu, BSc1,2*, Lin Hanyang, PhD1,2*, Katharina Rothe, PhD1,3*, Min Chen, MD, PhD1*, Jens Ruschmann, PhD1*, Oleh Petriv, PhD4*, Kieran O'Neill, PhD1*, Tobias Maetzig, MD1*, David Knapp, PhD1,2*, Naoto Nakamichi, MD, PhD5, Ryan Brinkman, PhD1,3*, Inanc Birol, PhD3,6*, Donna L Forrest, MD7*, Carl Hansen, PhD4*, R. Keith Humphries, MD, PhD2,8, Connie J. Eaves, PhD2,3,8 and Xiaoyan Jiang, MD, PhD2,3,9

1Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada
2Department of Medicine, University of British Columbia, Vancouver, BC, Canada
3Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
4Center for High-Throughput Biology and Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada
5Terry Fox Laboratory BC Cancer Agency, Vancouver, BC, Canada
6Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
7Leukemia/Bone Marrow Transplant Program of British Columbia, BC Cancer Agency, Vancouver, BC, Canada
8Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada
9Terry Fox Laboratory, BC Cancer Research Centre, Vancouver, BC, Canada

4:45 PM

Ajay Abraham, PhD1, Shaowei Qiu, MD1*, Balu K Chacko, PhD2*, Hui Li, BS1*, Andrew J Paterson, PhD1*, Jianbo He, MD1, Puneet Agarwal, PhD1*, Mansi Shah, PhD1, Robert S. Welner, PhD1, Victor M Darley-Usmar, PhD2* and Ravi Bhatia, MD1

1Division of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
2Department of Pathology. Mitochondrial Medicine Laboratory, University of Alabama at Birmingham, Birmingham, AL

5:00 PM

Katharina Rothe, PhD1,2*, Akie Watanabe3*, Donna L. Forrest, MD4, Sharon Gorski, PhD5,6*, Robert Young, PhD7* and Xiaoyan Jiang, MD-PhD1,8,9

1Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
2BC Cancer, Terry Fox Laboratory, Vancouver, BC, Canada
3BC Cancer Terry Fox Laboratory, Vancouver, BC, Canada
4Leukemia/BMT Program of BC, BC Cancer, Vancouver, BC, Canada
5Genome Sciences Centre, BC Cancer, Vancouver, Canada
6Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada
7Department of Chemistry, Simon Fraser University, Burnaby, Canada
8BC Cancer Research Centre, Vancouver, BC, Canada
9Department of Medicine, University of British Columbia, Vancouver, BC, Canada

5:15 PM

Sarah Pagliaro, Pharm D1,2*, Christophe Desterke3*, Herve Acloque, PhD4*, Annelise Bennaceur-Griscelli, MD, PhD5* and Ali G Turhan, MD, PhD6

1Inserm U935 University Paris Sud, Villejuif, France
2Science Without Borders, CAPES – Brasília, Brazil, Sao Paolo, Brazil
3Inserm U935, IFR 89, Paris 11 University, Villejuif, FRA
4Inserm U935 and INRA, Villejuif, France
5Department of Hematology, Inserm U935 University Paris Sud, Villejuif, France
6Hopital Bicetre-Paris Sud 11 University, Le Kremlin Bicetre, France

5:30 PM

Christian Schuerch, MD, PhD, Graham L. Barlow, BA*, Salil S. Bhate, MMath*, Nikolay Samusik, PhD*, Garry P. Nolan, PhD* and Yury Goltsev, PhD*

Baxter Laboratory for Stem Cell Biology, Stanford University School of Medicine, Stanford, CA

5:45 PM

Rahul Kumar, PhD1*, Maximilian Marten, Bachelors2*, Valentina Minciacchi, Ph.D3*, Raquel Pereira, M.Sc3*, Costanza Zanetti, MSc3*, Nina Hyduk, M.Sc3*, Thomas Oellerich, MD4*, Hans Michael Kvasnicka, MD5*, Joel Spencer, PhD6*, Frank Schnuetgen, PhD7*, Charles Lin, PhD8*, Cristina Lo Celso, PhD9,10*, Melanie Meister, PhD3*, Franck Emmanuel Nicolini, MD, PhD11,12,13 and Daniela S. Krause, MD3,14

1Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Hessen, Germany
2DZNE Bonn, Bonn, Germany
3Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt Am Main, Germany
4University Hospital Frankfurt, Department of Medicine II, Hematology-Oncology, Frankfurt am Main, Germany
5Senckenberg Institute of Pathology, University of Frankfurt, Frankfurt, Germany
6University of California, Merced, Boston, MA
7Abteilung für Molekulare Hämatologie, Universitätsklinikum Frankfurt am Main, Frankfurt Am Main, DEU
8Massachusetts General Hospital, Boston
9Imperial College, London, United Kingdom
10Francis Crick Institute, London, United Kingdom
11INSERM U590, CRCL, Lyon, France
12Hematology, Centre Leon Berard, Lyon, France
13Centre Hospitalier Lyon Sud, LYON Cedex 03, FRA
14University of Frankfurt, Frankfurt Am Main, MA, Germany

*signifies non-member of ASH