-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

632.Oral3.6 632. Chronic Myeloid Leukemia: Therapy: Treatment Discontinuation, Dose Reduction, and Prognostic Indicators

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Adult, Biological, Diseases, Therapies, CML, Pediatric, Study Population, Clinically relevant, Myeloid Malignancies, TKI
Sunday, December 10, 2017: 7:30 AM-9:00 AM
Bldg A, Lvl 4, Marcus Aud. (Georgia World Congress Center)
Moderators:
Sarit Assouline, MD, McGill University Jewish General Hospital and Susanne Saussele, MD , University of Heidelberg
Disclosures:
Assouline: Lundbeck: Other: Advisory Board; Paladin: Speakers Bureau; Pfizer: Speakers Bureau; Bristol Myer Squibb: Speakers Bureau; Roche Canada: Consultancy. Saussele: Novartis: Honoraria, Research Funding; Pfizer: Honoraria; BMS: Honoraria, Research Funding; Incyte: Honoraria.
7:30 AM

Susanne Saussele, MD 1, Johan Richter, MD, PhD2*, Joelle Guilhot, PhD3, Henrik Hjorth-Hansen, MD4, Antonio Medina de Almeida, MD, PhD5*, Jeroen J. W. M. Janssen, MD6*, Jiri Mayer, MD7, Perttu Koskenvesa, MD8*, Panayiotis Panayiotidis, MD, PhD9*, Ulla Olsson-Strömberg, MD, PhD10*, Juan Luis Steegmann, MD, PhD11, Hanne Vestergaard, MD12*, Hans Ehrencrona, MD, PhD13*, Veli Kairisto14*, Kateřina Machová Poláková, PhD15*, Martin Müller, MD16*, Satu Mustjoki, MD, PhD8,17, Marc G. Berger, MD, PhD18*, Philippe Rousselot, MD19,20,21*, Martine Escoffre-Barbe, MD22*, Gabriel Etienne, MD, PhD23*, Jolanta Dengler, MD24*, Françoise Rigal-Huguet, MD25*, Nikolas von Bubnoff, MD26*, Hana Klamova, MD15*, Edgar Faber, MD27*, François Guilhot, MD3*, Kourosh Lotfi, MD28*, Delphine Rea, MD29, Tim H. Brümmendorf, MD30, Gorgine de Greef, MD31*, Leif Stenke, MD32,33*, Franck Emmanuel Nicolini, MD, PhD34,35,36, Laurence Legros, PhD, MD37*, Andreas Burchert, MD38, Jaroslava Voglová, MD39*, Aude Charbonnier, MD40*, Emmanuel Gyan, MD-PhD41, Maria-Elisabeth Goebeler, MD42*, Peter E. Westerweel, MD43*, Andreas Hochhaus, MD44, Markus Pfirrmann45* and Francois-Xavier Mahon, MD, PhD46

1Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
2Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden
3INSERM CIC 1402, CHU de Poitiers, Poitiers, France
4Department of Hematology, St Olavs Hospital, Trondheim, Norway
5Instituto Portugues de Oncologia de Lisboa de Francisco Gentil, Lisbon, Portugal
6Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
7Department of Internal Medicine, Hematology and Oncology, Masaryk University and University Hospital Brno, Brno, Czech Republic
8Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Comprehensive Cancer Center, Helsinki, Finland
9Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
10Department of Hematology, University Hospital Uppsala, Uppsala, Sweden
11Servicio de Hematologia y Grupo 44 IIS-IP, Hospital Universitario de la Princesa, Madrid, Spain
12Department of Hematology, Odense University Hospital, Odense, Denmark
13Department of Clinical Genetics, Skåne University Hospital, Lund, Sweden
14Department of Clinical Chemistry, Turku University Central Hospital, Turku, Finland
15Institute of Hematology and Blood Transfusion, Prague, Czech Republic
16Institute for Hematology and Oncology (IHO GmbH), Mannheim, Germany
17Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland
18Hématologie Biologique and EA 7453 CHELTER, CHU Estaing and Université Clermont Auvergne, Clermont-Ferrand, France
19Department of Hematology and Oncology, Centre Hospitalier de Versailles, INSERM UMR 1173, Université Versailles Saint-Quentin-en-Yvelines, Université Paris Saclay, Le Chesnay, France
20Hôpital de Versailles, Le Chesnay, France
21Fi-LMC group, Pessac, France
22Service d'Hématologie Adulte, CHU de Rennes, Rennes, France
23Centre Régional de Lutte Contre le Cancer de Bordeaux et du Sud-Ouest, Bordeaux, France
24Onkologische Schwerpunktpraxis Heilbronn, Heilbronn, Germany
25Centre Hospitalier Universitaire (CHU) de Toulouse, Toulouse, France
26Innere Medizin I Schwerpunkt Hämatologie, Onkologie und Stammzelltransplantation, Universitätsklinikum Freiburg, Freiburg, Germany
27Department of Hemato-Oncology, Palacký University Olomouc, Faculty of Medicine and Dentistry, Olomouc, Czech Republic
28Department of Hematology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
29Service d'Hématologie adulte et Centre d'Investigation Clinique Hôpital Saint Louis, Paris, France
30Uniklinik RWTH Aachen, Aachen, Germany
31Department of Hematology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, Netherlands
32Division of Hematology, Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden
33Division of Hematology, Department of Medicine, Karolinska Institute, Stockholm, Sweden
34Hématologie Clinique, Centre Léon Bérard, Lyon, France
35Hématologie clinique 1G, Centre Hospitalier Lyon Sud, Pierre Benite, France
36INSERM U1052, Centre de recherche en cancérologie de Lyon (CRCL), Lyon, France
37Hematology department, Centre Hospitalier Universitaire de Nice, Nice, France
38Klinik für Innere Medizin, Schwerpunkt Hämatologie, Onkologie und Immunologie, Universitätsklinikum Marburg, Marburg, Germany
394th Department of Internal Medicine - Hematology, Charles University, Faculty Hospital and Faculty of Medicine, Hradec Králové, Czech Republic
40Paoli-Calmettes Institute, Marseille, France
41Hématologie et Thérapie Cellulaire, CHU de Tours, Tours, France
42Medizinische Klinik und Poliklinik, Universitätsklinikum Würzburg, Würzburg, Germany
43Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
44Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany
45Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität, München, Germany
46Bergonié Cancer Institute INSERM Unit 916, University of Bordeaux, Bordeaux, France

7:45 AM

Neil P. Shah, MD, PhD1, Valentín García Gutiérrez, PhD2, Antonio Jiménez-Velasco, MD3*, Sarah M Larson, MD4*, Susanne Saussele, MD 5, Delphine Rea, MD6, François-Xavier Mahon, MD, PhD7, Moshe Levy, MD8, María Teresa Gómez-Casares, MD, PhD9*, Fabrizio Pane, MD10, Franck-Emmanuel Nicolini, MD, PhD11, Michael J. Mauro, MD12, Oumar Sy, PhD13*, Patricia Martin Regueira13* and Jeffrey H. Lipton, PhD, MD, FRCPC14*

1UCSF School of Medicine, San Francisco, CA
2Servicio Hematologia y Hemoterapia, Hospital Universitario Ramon y Cajal, Madrid, Spain
3Hospital Universitario Carlos Haya, Malaga, Spain
4David Geffen School of Medicine at UCLA, Los Angeles, CA
5Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
6Hématologie, Hôpital Saint-Louis, Paris, France
7Université Bordeaux Segalen, Bordeaux, France
8Baylor University Medical Center at Dallas, Dallas, TX
9Hospital Universitario De Gran Canaria Dr., Negrin, Spain
10Università degli Studi di Napoli, Federico II, Italy
11Hématologie clinique 1G, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France
12Myeloproliferative Neoplasms Program, Memorial Sloan Kettering Cancer Center, New York, NY
13Bristol-Myers Squibb, Princeton, NJ
14Cancer Clinical Research Unit, Princess Margaret Cancer Centre, University of Toronto, Ontario, Canada

8:00 AM

Adi J. Klil-Drori, MD1, Hui Yin, MSc2*, Laurent Azoulay, PhD2*, Alexa Del Corpo3*, Michael Harnois4*, Michel-Olivier Gratton4*, Lambert Busque, MD5 and Sarit Assouline, MD6

1Segal Cancer Center, Jewish General Hospital, Montreal, QC, Canada
2Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada
3Jewish General Hospital, Montreal, QC, Canada
4Hopital Maisonneuve Rosement, Montreal, QC, Canada
5University of Montreal, CIUSSS de l'Est de l'Ile de Montreal, Maisonneuve-Rosemont Hospital, Montreal, Canada
6Segal Cancer Center, Lady Davis Institute, McGill University Jewish General Hospital, Montreal, QC, Canada

8:15 AM

Frédéric Millot1*, Joelle Guilhot, PhD2, Meinolf Suttorp, MD, PhD3, Natacha Maledon2*, Meral Günes Adalet, MD4*, Petr Sedlacek, MD5*, Eveline S. de Bont, MD6, Chi Kong Li, MD7*, Krzysztof Kalwak, MD8*, Birgitte Lausen, MD9, Gordana Jakovljevic, MD10*, Michael Dworzak, MD11*, Andrea Hraskova, MD12*, Barbara De Moerloose, MD, PhD13*, Roula Farah, MD14*, Andrea Biondi, MD15 and Andre Baruchel, MD16

1Department of Pediatric Hematology-Oncology, CHU Poitiers, Poitiers, France
2Inserm CIC 1402, University Hospital, Poitiers, France
3University Hospital Carl Gustav Carus,, Dresden, Germany
4Uludağ University Hospital, Görükle Bursa, Turkey
5Department of Pediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic
6University Medical Center Groningen, University of Groningen, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
7Department of Pediatrics, Prince of Wales Hospital, Hong Kong, China
8Department of Pediatric Hematology Oncology and Transplantation, Wroclaw Medical University, Wroclaw, Poland
9Department of Pediatrics, Rigshospitalet, Copenhagen, Denmark
10Department of Pediatric Hematology Oncology Immunology and Medical Genetic, Children Hospital, Zagreb, Croatia
11Department of Pediatrics, St. Anna Children's Hospital and Children’s Cancer Research Institute, Vienna, Austria
12University Children's Hospital, Bratislava, Slovakia
13Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium
14Saint George Hospital University Medical Centre, Beirut, Lebanon
15Centro Ricerca Tettamanti, University of Milano-Bicocca San Gerardo Hospital, Monza, MI, Italy
16Hopital Robert Debré, Paris, France

8:30 AM

Young Rok Do, MD, PhD1, Hawk Kim, MD, PhD2, Jae-Yong Kwak3, Jeong-A Kim4, Hyeoung-Joon Kim5, Joon Seong Park, MD6*, Jooseop Chung, MD, PhD7, Ho-Jin Shin, MD, PhD7*, Sung-Hyun Kim, MD, PhD8, Udomsak Bunworasate, MD9*, Chul Won Choi, MD, PhD10*, Narcisa Sonia Cornejo Comia, MD11*, Dae Young Zang12*, Sukjoong Oh, MD, PhD13, Saengsuree Jootar, MD14*, Ary Harryanto Reksodiputro, MD, PhD15*, Won-Sik Lee, MD16, Yeung-Chul Mun, MD, PhD17*, Jee Hyun Kong, MD18*, Priscilla B. Caguioa, MD19*, Jinny Park, MD, PhD20*, Chul W. Jung, MD, PhD21 and Dong-Wook Kim, MD, PhD22

1Division of Hematology-Oncology, Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of (South)
2Ulsan University Hospital, College of Medicine, Ulsan, KOR
3Division of Hematology-Oncology, Chonbuk National University Medical School, Chonbuk National University Hospital, Jeonju, Korea, Republic of (South)
4Department of Hematology, The Catholic University of Korea, St. Vincent’s Hospital, Suwon, Korea, Republic of (South)
5Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea, Republic of (South)
6Ajou University School of Medicine, Suwon, Korea, Republic of (South)
7Department of Hematology-oncology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea, Republic of (South)
8Department of Internal Medicine, Dong-A University College of Medicine, Dong-A University Hospital, Busan, Korea, Republic of (South)
9King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
10Korea University, Guro Hospital, Seoul, Korea, Republic of (South)
11Mary Mediatrix Med. Ctr., Lipa City, PHL
12Department of Internal Medicine, Hallym University College of Medicine, Hallym University Hospital, Anyang, Korea, Republic of (South)
13Division of Hematology-Oncology, School of Medicine, Sungkyunkwan University, Kangbuk Samsung Hospital, Seoul, Korea, Republic of (South)
14Ramathibodi Hospital Faculty of Medicine, Bangkok, THA
15Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
16Inje University Busan Paik Hospital, Busan, Korea, Republic of (South)
17Ewha Womans University Mokdong Hospital, Seoul, Korea, Republic of (South)
18Department of Hematology Oncology, Wonju College of Medicine, Yonsei University, Wonju, South Korea
19St. Luke's Medical Center Cancer Institute, Quezon City, PHL
20Gachon University Gil Medical Center, Incheon, Korea, Republic of (South)
21Samsung Medical Center, Seoul, KOR
22Division of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)

8:45 AM

Delphine Rea, MD1, Jean-Michel Cayuela, PhD2*, Stephanie Dulucq, PhD3* and Gabriel Etienne, MD, PhD4*

1Adult Hematology department, Hôpital Saint-Louis, Paris, France
2Molecular Biology Laboratory, Hôpital Saint-Louis, Paris, France
3Molecular Biology Laboratory, Hôpital Haut Lévèque, Pessac, France
4Hematology Department, Institut Bergonie, Bordeaux, France

*signifies non-member of ASH