-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

101. Red Cells and Erythropoiesis, Structure and Function, Metabolism, and Survival, Excluding Iron: Poster II

Red Cells and Erythropoiesis, Structure and Function, Metabolism, and Survival, Excluding Iron Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 4, 2016: 6:00 PM-8:00 PM
Hall GH (San Diego Convention Center)

Constance Tom Noguchi, PhD and Heather Marie Rogers, MS

Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

Andrea Bacigalupo, MD1, Rosi Oneto2*, Schrezenmeier Hubert3*, Dufour Carlo4*, Seiji Kojima, MD, PhD5*, Surapol Issaragrisi6*, Dae Chul Jeong, MD, PhD7, Xiaofan Zhou8*, Yizhou Zheng9*, Hoechsmann Britta3* and Carlos Vallejo10*

1Division of Hematology and Bone Marrow Transplantation, Catholic University Policlinico Gemelli, Roma, Italy
2Division of Hematology, Universita' Cattolica, Policlinico Gemelli, Roma, Italy
3GRC Blood Transfusion Service Baden Wuttenberg Hessen and University Hospital, Universitaetsklinikum Ulm, Inst. Of Transfusion Medicine and Immunogenetics, ULM, Germany
4Division of Hematology, Istituto G Gaslini, Genova, Italy
5Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
6Division of Hematology, MAhidol University, BANGKOG, Thailand
7Pediatrics, Our Lady of Mercy Hospital, Incheon, South Korea
8Chinese Academy of Medical Science (CAMS) & Peking Union Medical College, Blood Disease Hospital, Institute of Hematology, Tianjin, China
9Chinese Academy of Medical Science (CAMS)& Peking Union Medical College, Blood Disease Hospital, Institute of Hematology,, Tianjin, China
10Division of Hematology, Hospital Universitario de Donostia, San Sebastian, Spain

Brian M. Dulmovits, MS1, Nan Wang, Ph.D.2*, Corinne LaVasseur, BA3*, Julien Papoin, MS4*, Hongxia Yan, MS5*, Xiuli An, MD, PhD6, Jeffrey M Lipton, MD, PhD1,7,8, Narla Mohandas9, Anupama Narla, MD10 and Lionel Blanc, PhD4

1Hofstra Northwell School of Medicine, Hempstead, NY
2Stanford School of Medicine, Stanford
3Department of Pediatrics, Division of Hematology/Oncology, Stanford University School of Medicine, Palo Alto, CA
4The Feinstein Institute for Medical Research, Manhasset, NY
5Laboratory of Membrane Biology, New York Blood Center, New York, NY
6Membrane Biology Laboratory, New York Blood Center, New York, NY
7Hematology/Oncology and Stem Cell Transplantation, Cohen Children's Medical Center, New Hyde Park, NY
8Department of Pediatrics, The Feinstein Institute for Medical Research, Manhasset, NY
9Red Cell Physiology Laboratory, New York Blood Center, New York, NY
10Department of Pediatrics, Division of Hematology/Oncology, Lucile Packard Children’s Hospital at Stanford University, Stanford, CA

Zhangzhe Peng, MD1,2*, Renna Luo, MD3*, Anren Song, PhD4*, Kaiqi Sun, BS5, Hong Liu, MD6, Yujin Zhang, PhD7, Morayo G. Adebiyi, BS5*, Yang Xia, MD, PhD5, Rodney E. Kellems, PhD5* and Aji Huang, BS, MS5*

1Department of Nephrology, Xiangya Hospital, Central South University, Changsha, China
2University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX
3Department of Nephrology, The First Affiliated Hospital of Dalian Medical University, dalian, China
4University of Texas-Medical School, Houston, TX
5Department of Biochemistry and Molecular Biology, UTHSC-Houston Medical School, Houston, TX
6University of Texas Health Science Center At Houston, Houston, TX
7Univesity of Texas Health Science Center, Houston, TX

Yingchi Zhang1*, Jingliao Zhang1*, Wenbin An1*, Yang Wan, MD2*, Jie Gao1*, Lihong Shi1*, Tao Cheng, MD3 and Xiaofan Zhu, MD2

1State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
2State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
3State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin, China

Hiroshi Kohara, PhD1*, Hiromi Ogura, MD, PhD2*, Takako Aoki, MLS2*, Chika Sakamoto3*, Yoshie Ogawa1*, Shohei Miyamoto, PhD1*, Hitoshi Kanno, MD, PhD2 and Kenzaburo Tani, MD, PhD1,3,4

1Project Division of ALA Advanced Medical Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
2Dept. Transfusion Medicine and Cell Processing, Tokyo Women's Medical University, Tokyo, Japan
3Division of Molecular and Clinical Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
4Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital, Fukuoka, Japan

Zhangbiao Long, master1*, Yali Du, bachelor2*, Hongmin Li, master2*, Zhao Wang, M.D.3 and Bing Han, M.D.2*

1Department of hematology, Peking union medical college/ Peking union medical college hospital, Beijing, China
2Department of hematology, Peking union medical college hospital, Beijing, China
3Department of Hematology, Capital Medical University/Beijing Friendship Hospital, Beijing, China

Jong-Wook Lee, MD1, Eric Scott Bachman, MD, PhD2, Rasha Aguzzi, MS3*, Jun Ho Jang, MD, PhD4*, Jin Seok Kim, MD, PhD5*, Scott T. Rottinghaus, MD6*, Lori Shafner, PhD6* and Jeff Szer, MB, BS, FRACP7

1Division of Hematology, Catholic Blood and Marrow Transplantation Center, Cancer Research Institute, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
2Translational Medicine, Alexion Pharmaceuticals, Inc., Cambridge, MA
3Biostatistics, Alexion Pharmaceuticals, Inc., Cambridge, MA
4Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea
5Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
6Global Development, Alexion Pharmaceuticals, Inc., New Haven, CT
7Clinical Haematology, Royal Melbourne Hospital, Parkville, Australia

Monica Konar, PhD*, Eduardo Lujan* and Dan Granoff, MD*

Center for Immunology and Vaccine Development, UCSF Benioff Children's Hospital Oakland, Oakland, CA

Eduard J van Beers, MD, PhD1*, Wilma Barcellini2*, Stefan W. Eber, MD3, Janet L Kwiatkowski, MD4*, Jennifer A Rothman, MD5, Ellis J Neufeld, MD, PhD6, Mukta Sharma, MD, MPH7, D Holmes Morton, MD8*, Bertil Glader, MD, PhD9, Nina Kollmar, MD10*, Hassan M. Yaish11*, Jenny M. Despotovic, DO, MS12, Christine M. Knoll, MD13, Yves D. Pastore, MD14, Kevin Kuo, BSc, MD15, Peter E. Newburger, MD16, Marcin W Wlodarski, MD17*, Alexis A. Thompson, MD, MPH18, Yaddanapudi Ravindranath19, Winfred C. Wang, MD20, Heng Wang, MD21*, Joachim B. Kunz, MD22*, Vicky R. Breakey, BSc, MD, MEd, FRCPC23, Melissa J. Rose, DO24*, Melissa Rhodes, MD25, Heather A Bradeen, MD26*, Sujit Sheth, MD27*, Dongjing Guo, MS28*, Wendy B. London, PhD28* and Rachael F. Grace, MD29

1Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
2Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
3Red cell laboratory, Children‘s Hospital, University Würzburg, Schwerpunktpraxis für Pädiatrische Hämatologie- Onkologie, Munich, Germany
4Children's Hospital of Pennsylvania and Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA
5Duke University Medical Center, Durham, NC
6Boston Hemophilia Center, Boston, MA
7Children's Mercy Hospital, Kansas City, MO
8Central Pennsylvania Clinic, Belleville, PA
9Department of Pediatrics, Division of Hematology/Oncology, Lucile Packard Children’s Hospital at Stanford University, Stanford, CA
10Klinikum Kassel GmbH, Kassel, Germany
11Primary Children’s Hospital, University of Utah, Salt Lake City, UT
12Texas Children's Hematology Center, Baylor College of Medicine, Houston, TX
13Phoenix Children's Hospital, Phoenix, AZ
14Division of Hematology-Oncology, Department of Pediatrics, CHU Sainte-Justine, Montreal, QC, Canada
15University of Toronto, University Health Network, Ontario, Canada
16University of Massachusetts Medical School, Worcester, MA
17Division of Pediatric Hematology and Oncology, Department of Pediatrics, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
18Division of Hematology, Oncology & Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
19Wayne State University School of Medicine - Children’s Hospital of Michigan, Detroit, MI
20Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
21DDC Clinic for Special Needs Children, Middlefield, OH
22Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany
23McMaster University, Hamilton, ON, Canada
24Nationwide Children’s Hospital and The Ohio State University College of Medicine, Columbus, OH
25University of Mississippi Medical Center, Jackson, MS
26The University of Vermont Children’s Hospital, Burlington, VT
27New York Presbyterian Hospital, Weil Cornell Medical College, New York, NY
28Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA
29Dana Farber Boston Children’s Cancer and Blood Disorder Center, Boston, MA

Xuan Yuan, MD, MSc1, Guangwei Yang, Ph.D2*, Jane A Thanassi2*, Manuel D Galvan, Ph.D2*, Steven D Podos, Ph.D2*, Mingjun Huang, PhD3* and Robert A. Brodsky, MD1

1Division of Hematology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD
2Achillion Pharmaceuticals, New Haven, CT
3Achillion Pharmaceuticals, Inc, New Haven, CT

Jakob Pugi, BSc1*, Luke J. Drury, PhD, BS2, Jacob C. Langer, MD, FRCSC3,4*, Sheila Butchart, BScN, RN5*, Michelle Fantauzzi, BScN, RN5*, Jillian Baker, MD, MSc6,7*, Victor S. Blanchette, FRCP, FRCPC8, Melanie Ann Kirby-Allen, MD, FRCPC, MBBS9* and Manuel Carcao, MD10

1Department of Paediatrics, Division of Haematology/Oncolog, The Hospital for Sick Children, Toronto, ON, Canada
2Prevention Genetics, Marshfield, WI
3Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada
4Department of Surgery, University of Toronto, Toronto, ON, Canada
5Department of Nursing, The Hospital for Sick Children, Toronto, ON, Canada
6Pediatric Hematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
7Department of Pediatrics, St. Michael's Hospital, Toronto, ON, Canada
8Department of Pediatrics, Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada
9Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, CAN
10Paediatrics; Division of Haematology/Oncology and Child Health Evaluative Sciences, Research Insititute, Hospital for Sick Children, Toronto, ON, Canada

Archana M Agarwal, M.D.1,2, N. Scott Reading, Ph.D.1,2,3*, Kimberly Frizzell, PhD4*, Wei Shen, PhD4*, Shelly Sorrells, PhD4*, Mohamed E Salama, M.D.1,2, Josef T. Prchal, MD2,5,6, Hassan M. Yaish7*, Jay L Patel, MD1,2* and Robert D. Christensen, MD8*

1Department of Pathology, University of Utah, Salt Lake City, UT
2Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT
3Division of Hematology, School of Medicine, University of Utah, Salt Lake City, UT
4Genomics, ARUP Laboratories, Salt Lake City, UT
5Division of Hematology, University of Utah, Salt Lake City, UT
6Department of Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT
7Primary Children’s Hospital, University of Utah, Salt Lake City, UT
8Division of Neonatology, University of Utah, Department of Pediatrics, Salt Lake City, UT

Francois Girodon, MD, PhD1,2, Fabrice Airaud, PhD3*, Garrec Céline, MD3*, Pacault Mathilde4*, Dumont Solenne3*, Ricordeau Ingrid3*, Bézieau Stéphane, MD, PhD3* and Betty Gardie, PhD4,5*

1Hospital University Center (CHU), Dijon, France
2INSERM, UMR866, Dijon, France
3Laboratoire de Génétique Moléculaire, CHU Nantes, Nantes, France
4Centre de Recherche en Cancérologie Nantes Angers, Nantes, France
5EPHE, Nantes, France

Bernd Jilma, MD1, James C Gilbert, MD2*, Sandip Panicker, PhD3, Graham C Parry, PhD2*, Michael Fillitz, MD4*, Schenk Thomas5*, Christian Sillaber, M.D.6*, Johann Bartko, MD1* and Ulrich Jaeger, MD7

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
2True North Therapeutics, Inc., South San Francisco, CA
3True North Therapeutics, Inc., South San Francisco
4Hanusch Krankenhaus, Vienna, Austria
5Internal Medicine, Universitätsklinikum, St. Pölten, St Pölten, Austria
6Department of Internal Medicine I, Division of Hematology, Medical University of Vienna, Vienna, Austria
7Division of Hematology and Hemostaseology, Medical University of Vienna, Wien, Austria

Katie Giger Seu, PhD1*, Julien Papoin, MS2*, Rose Fessler1*, Jimmy Hom, BA2, Gang Huang, PhD3, Narla Mohandas4, Lionel Blanc, PhD2 and Theodosia A. Kalfa, MD, PhD1

1Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
2The Feinstein Institute for Medical Research, Manhasset, NY
3Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
4Red Cell Physiology Laboratory, New York Blood Center, New York, NY

Hong Liu, MD1,2,3, Yujin Zhang, Ph.D4, Angelo D’Alessandro, Ph.D5*, Travis Nemkov6*, Jacob Couturier, PhD7*, Shushan Zhao, Ph.D8*, Kirk C Hansen, PhD6*, Andrew T. Lovering, Ph.D9*, Robert Roach, PhD10*, Rodney E. Kellems, PhD1*, Holger K. Eltzschig, MD/PHD11*, Michael R. Blackburn, PhD12* and Yang Xia, MD, PhD1,13

1Department of Biochemistry & Molecular Biology, University of Texas, Health Sciences Center at Houston, Houston, TX
2University of Texas Health Science Center at Houston, Graduate School of Biomedical Sciences, Houston
3Central South University, Department of Otolaryngology, Xiangya Hospital, Changsha, China
4Department of Biochemistry & Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX
53Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora
6Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
7Department of Internal Medicine, UTHSC-Houston Medical School, Houston, TX
8Biochemistry & Molecular Biology, the University of Texas – Houston Medical School, Houston, TX
9University of Oregon, Eugene
10University of Colorado, Aurora, CO
11University of Colorado, Dennver
12Department of Biochemistry and Molecular Biology, UTHSC-Houston Medical School, Houston, TX
13University of Texas Graduate School of Biomedical Science, Houston, TX

Binal N. Shah, PhD1*, Philip E Thuma2*, N. Scott Reading, Ph.D.3,4*, Josef T. Prchal, MD5 and Victor R. Gordeuk, MD1

1Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, Chicago, IL
2Malaria Research Trust, Choma, Zambia
3Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT
4Division of Hematology, School of Medicine, University of Utah, Salt Lake City, UT
5Division of Hematology, University of Utah, Salt Lake City, UT

Paraskevi Rea Oikonomidou, M.D.1*, Ping La, PhD1*, Ritama Gupta, MSc1*, Vania Lo Presti1*, Carla Casu, PhD1*, Laura Breda, PhD1*, Deborah Watson, PhD2*, Rajasekhar NVS Suragani, PhD3, Ravindra Kumar, PhD3* and Stefano Rivella, PhD1

1Children's Hospital of Philadelphia, Philadelphia, PA
2University of Pennsylvania, Philadelphia, PA
3Acceleron Pharma, Cambridge, MA

Sandra Martinez-Morilla, PhD1*, Srividhya Venkatesan, MS1*, Seibel Katharina, PhD2*, Jeffrey D. Cooney, B.S., M.S.3, Barry H. Paw, M.D., Ph.D.4, Dirk Gorlich, PhD2* and Shilpa M Hattangadi, M.D.5

1Pediatric Hematology-Oncology, Yale School of Medicine, New Haven, CT
2Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
3Hematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
4Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
5Division, Pediatric Hematology-Oncology, Yale School of Medicine, New Haven, CT

Benoît Henry, M.D.1,2*, Camille Roussel, M.D.1*, Papa Alioune Ndour, Ph.D.1*, Mario Carucci, Ph.D.1*, Julien Duez, Ph.D.1*, Aurélie Fricot, MSc.1*, Florentin Aussenac, MSc.3,4*, Hilaire Akpovi, M.D.5*, David Courtin, Ph.D.3,6*, Jérôme Clain, PharmD, Ph.D.3,7*, Yves Colin Aronovicz, PhD8, André Garcia, M.D., Ph.D.3,5,9*, Audrey Sabbagh, PharmD, Ph.D.3,7* and Pierre A Buffet, M.D., Ph.D.1*

1Université Sorbonne Paris Cité, Université Paris Diderot, Inserm, INTS, Unité Biologie Intégrée du Globule Rouge, Laboratoire d’Excellence GR-Ex, Paris, France
2APHP, Hôpital Necker Enfants Malades, Centre d'Infectiologie Necker-Pasteur, Institut Imagine, Paris, France
3Institut de Recherche pour le Développement, UMR216, MERIT, Paris, France
4Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance, Cotonou, Benin
5Centre d'Etudes et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance, Cotonou, Benin
6Sorbonne Universités, Université Paris Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
7Sorbonne Paris Cité, Université Paris Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
8UMR 1134 Biologie Integrée du Globule Rouge, Université Sorbonne Paris Cité/Université Paris Diderot/INSERM/INTS/Laboratoire d´Excellence GR-Ex, Paris, France
9Université Paris Descartes, Sorbonne Paris Cité, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France

Jihyun Song, PhD1*, Krishna M Sundar, MD2*, Radhika Gangaraju, MD3, Subhashree Sundar4*, Perumal Thiagarajan, MD5 and Josef T. Prchal, MD1,6,7,8

1Division of Hematology, University of Utah, Salt Lake City, UT
2Sleep Wake Center and Division of Pulmonology, Department of Medicine, University of Utah, Salt Lake City, UT
3Division of Hematology and Oncology, Department of Medicine, University Of Utah, Salt Lake City, UT
4Driehaus College of Business, DePaul University, Chicago, IL
5Department of Medicine and Pathology, Baylor College of Medicine, Houston, TX
6Departments of Medicine and Pathophysiology, Charles University School of Medicine,, Prague, Czech Republic
7Department of Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT
8Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT

Theresa L. Coetzer, PhD, Alisje Churchyard, BSc Hons* and Melanie Wepener, MSc*

Wits Research Institute for Malaria, Department of Molecular Medicine and Haematology, University of the Witwatersrand and NHLS, Johannesburg, South Africa

Radhika Gangaraju, MD1, Krishna M Sundar, MD2*, Jihyun Song, PhD3* and Josef T. Prchal, MD3

1Division of Hematology and Oncology, Department of Medicine, University Of Utah, Salt Lake City, UT
2Sleep Wake Center and Division of Pulmonology, Department of Medicine, University of Utah, Salt Lake City, UT
3Division of Hematology, University of Utah, Salt Lake City, UT

Kolomansky Albert, MD1,2*, Sahar Hiram-Bab, PhD3*, Naamit Deshet-Unger, MSc1*, Nathalie Ben-Califa, PhD1*, Dafna Gilboa, MSc1*, Tamar Liron, PhD4*, Howard S Oster, MD, PhD2,5, Moshe Mittelman, MD2,5, Yankel Gabet, DMD, PhD3* and Drorit Neumann, PhD1

1Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
2Department of Internal Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
3Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
4Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Mary A Risinger, PhD1*, Neha Dagaonkar2*, Georgios E Christakopoulos, MD3*, Jie Liu, PhD3*, Katie Giger Seu, PhD3*, Diamantis G Konstantinidis, BSc, PhD3*, Charles T Quinn, MD3, Satheesh Chonat, MD4, Clinton H Joiner, MD, PhD4, Kejian Zhang, MD2* and Theodosia A. Kalfa, MD, PhD3

1College of Nursing, University of Cincinnati, Cincinnati, OH
2Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
3Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
4Department of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplant, Aflac Cancer and Blood Disorders Center and Emory University School of Medicine, Atlanta, GA

Sven R Olson, MD1*, Thomas G. Deloughery, MD1 and Jason A Taylor, MD, PhD2

1Oregon Health and Science University, Portland, OR
2The Hemophilia Center, Oregon Health & Science University, Portland, OR

Sylvain Audia, MD, PhD1,2*, Benoit Bach, MD3*, Maxime Samson, MD, PhD1,3*, Vanessa Leguy, MD3*, Sabine Berthier, MD3* and Bernard Bonnotte, MD, PhD1,3*

1CR INSERM 1098, University of Bourgogne/Franche-Comté, Dijon, France
2Dijon University Hospital, Dijon, France
3Department of Internal Medicine and Clinical Immunology, University Hospital, Dijon, France

Ait Abdallah Nassim1*, Connes Philippe2*, Di Liberto Gaetana3,4*, Offredo Lucile5*, Ranque Brigitte6,7*, Debbache Karima8*, Jebali Amna9*, Habibi Anoosha10,11*, Pirenne France12,13*, Galacteros Frédéric10,12* and Bartolucci Pablo10,12*

1Centre de Référence des Syndromes Drépanocytaires Majeurs,Université Paris-Est Créteil, Créteil, Hôpital Henri-Mondor, Assistance Publique–Hôpitaux de Paris (AP–HP), creteil, France
2Laboratoire LIBM , Team "VascularBiology and Red Blood Cell". GRex member, Université Claude Bernard Lyon 1, Villeurbanne, France
3Laboratoire d’Excellence, GRex, Institut Mondor, 1INSERM-U955, Equipe 2: Transfusion et maladies du globule rouge, creteil, France
42Etablissement Français du Sang, Île-de-France Mondor,, creteil, France
5INSERM U970 - Centre de recherche Cardiovasculaire de Paris ,Equipe Epidemiologie Cardiovasculaire et Mort Subite, paris, France
6INSERM U970 - Centre de recherche Cardiovasculaire de Paris Equipe Epidemiologie Cardiovasculaire et Mort Subite, paris, France
7service de médecine interne,hopitale européen George Pompidou,APHP,Paris, Paris, France
8Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor, Assistance Publique–Hôpitaux de Paris (AP–HP), Université Paris-Est ., creteil, France
93Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor, Assistance Publique–Hôpitaux de Paris (AP–HP), Université Paris-Est Créteil, creteil, France
10Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor, Assistance Publique–Hôpitaux de Paris (AP–HP), Université Paris-Est Créteil, creteil, France
111INSERM-U955, Equipe 2: Transfusion et maladies du globule rouge, Laboratoire d’Excellence, GRex, Institut Mondor, creteil, France
12INSERM-U955, Equipe 2: Transfusion et maladies du globule rouge, Laboratoire d’Excellence, GRex, Institut Mondor, creteil, France
13Etablissement Français du Sang, Île-de-France Mondor, creteil, France

Yoshiko Murakami, MD PhD1*, Michi Kawamoto, MD2*, Norimitsu Inoue, MD PhD3*, Makiko Osato, DS4*, Shogo Murata, MD PhD1,5*, Sho Murase, MD2*, Hajime Yoshimura, MD2*, Yasutaka Ueda, MD, PhD4, Jun-Ichi Nishimura, MD, PhD4, Yuzuru Kanakura, MD, PhD4, Nobuo Kohara, MD2* and Taroh Kinoshita, PhD1

1Research Institute for Microbial Disease and World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan
2Department of Neurology, Kobe City Medical Center General Hospital, Kobe, Japan
3Osaka Medical Center for Cancer, Osaka, Japan
4Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan
5Department of Haematology/Oncology, Wakayama Medical University, Wakayama, Japan

Aishwarya Ravindran, MBBS1*, Janani Sankaran, MBBS2*, Min Shi, MD, PhD3, Eapen K. Jacob, MD4, Justin D. Kreuter, MD4*, Jeffrey L. Winters, MD4, C. Christopher Hook, MD1, Timothy G. Call, MD1, Ariela L. Marshall, MD1, Rajiv K. Pruthi, MD1, Aneel A. Ashrani, MD, MS1, Kebede H. Begna, MD1, Neil E. Kay, MD1 and Ronald S. Go, MD1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Department of Family Medicine, Eastern Virginia Medical School, Norfolk, VA
3Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
4Division of Transfusion Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Victor Chubukov*, Kendall Johnson*, Penelope A Kosinski*, Michelle Clasquin*, Abhishek Jha*, Hyeryun Kim*, Thomas P Roddy*, Elizabeth Merica*, Ann J Barbier*, Lenny Dang*, Lee Silverman* and Charles Kung*

Agios Pharmaceuticals, Inc., Cambridge, MA

Susana Brito dos Santos, MSc1*, Mark C. Allenby, MSc1*, Athanasios Mantalaris, PhD1* and Nicki Panoskaltsis, MD, PhD1,2

1Biological Systems Engineering Laboratory, Department of Chemical Engineering, Imperial College London, London, United Kingdom
2Department of Haematology, Imperial College London, London, United Kingdom

*signifies non-member of ASH