Marco Ruella, MD¹, David M. Barrett, MD, PhD^2*, Saad S Kenderian, MD^1,3, Olga Shestova, PhD^1*, Ted J. Hofmann, PhD^2*, John Scholler^4*, Simon F. Lacey, PhD, BSc^1*, J. Joseph Melenhorst, PhD¹, Farzana Nazimuddin^5*, Jessica Perazzelli, PhD^2*, David A Christian, PhD^6*, Christopher A Hunter, PhD^6*, David L Porter, MD⁷, Carl H. June, MD¹, Stephan A. Grupp, MD, PhD² and Saar I Gill, MBBS, PhD¹

¹Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
²Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
³Department of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN
⁴Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
⁵Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
⁶Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA
⁷Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA

Elad Jacoby, MD, Sang Minh Nguyen, BS^*, Kathryn M Welp^*, Haiying Qin, MS^*, Yinmeng Yang, BS^*, Christopher Daniel Chien, PhD, John Shern, M.D.^* and Terry J. Fry, M.D.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

EunJi Gang, MD PhD^1*, Yao-Te Hsieh, PhD^2*, Hye Na Kim^1*, Yann Duchartre, PhD^3*, Shishido Stephanie, PhD^3*, Markus Muschen, MD⁴, Elizabeth Wayner, PhD^3*, Nora Heisterkamp, PhD^5*, Halvard Bonig, MD, MA⁶ and Yong-Mi Kim, MD PhD MPH⁵

¹Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles
²Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA
³Children's Hospital Los Angeles, University of Southern California, Los Angeles
⁴Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
⁵Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA
⁶German Red Cross Blood Centre and Institute for Transfusion Medicine and Immunohematology, Johann-Wolfgang-Goethe University, Hematopoietic Cell Research Group, Frankfurt, Germany

EunJi Gang, MD PhD^1*, Hye Na Kim^1*, Yann Duchartre, PhD^1*, Stephanie Nicole Shishido, PhD^2*, Sajad Khazal, MD^2*, Etai Adam, MD^3*, Nour Abdel-Azim^1*, Chintan Parekh, MBBS^1*, Hisham Abdel-Azim, MD², Deepa Bhojwani, MD^1*, Nora Heisterkamp, PhD^2*, Alan S. Wayne, MD² and Yong-Mi Kim, MD PhD MPH²

¹Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles
²Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA
³Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles

Aaron Chang^1*, Tao Dao, PhD^1*, Andrew Scott^1*, Leonid Dubrovsky, MD^1*, Cheng Liu, PhD^2* and David A. Scheinberg, MD, PhD¹

¹Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY
²Eureka Therapeutics, Emeryville, CA

Tara Bree Gavcovich, BS^1,2, Kirsti Lorraine Walker, BS, MS¹, Myriam N. Bouchlaka, BS, PhD³ and Christian M Capitini, MD^4*

¹Department of Pediatric and Carbone Cancer Center, UW Madison, Madison, WI
²School of Medicine and Health Sciences, George Washington University, Washington, DC
³Department of Pediatrics and Carbone Cancer Center, University of Madison, Wisconsin, Madison, WI
⁴Department of Pediatric and Carbone Cancer Center, University of Wisconsin, Madison, WI

Ce Shi, PhD^1,2*, Lina Han, PhD^1*, Qi Zhang^3*, Kathryn G. Roberts⁴, Eugene Park^5*, Yoko Tabe, MD, PhD⁶, Rodrigo Omar Jacamo, PhD^3*, Hong Mu, MD, PhD^7*, Shuo-Chieh Wu^8*, Jin Zhou^9*, Helen Ma^1*, Zhihong Zeng, MD¹⁰, Nitin Jain, MD¹, Elias J Jabbour, MD¹, Markus Muschen, MD PhD¹¹, Sarah K Tasian, MD¹², Charles G. Mullighan, MBBS, MSc, MD¹³, David M. Weinstock¹⁴, David Fruman, PhD^15* and Marina Konopleva, MD, PhD¹⁰

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, First Affiliated Hospital, Harbin Medical University, Harbin, China
³Section of Molecular Hematology & Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Pathology, St. Jude Children's Research Hospital, Memphis, TN
⁵Department of Haematology, University of Cambridge, Cambridge, United Kingdom
⁶Juntendo University School of Medicine, Toyko, Japan
⁷Section of Molecular Hematology and Therapy, Leukemia Department, UT MD Anderson Cancer Center, Houston, TX
⁸Dana-Farber Cancer Institute, Boston, MD
⁹Department of Medicine, Hematology, The First Hospital Affiliated Harbin Medical University, Harbin, China
¹⁰Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
¹²Pediatric Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA
¹³Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
¹⁴Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹⁵University of California, Irvine, Irvine, CA

Yogin B Patel, PharmD^1*, Hagop M. Kantarjian, MD², Deborah Thomas, MD², Susan O'Brien, MD³, Farhad Ravandi, MD², Guillermo Garcia-Manero, MD⁴, Jorge E. Cortes², Marina Konopleva, MD, PhD², Nitin Jain, MD², Rebecca Garris^2*, Jane Autry, RN^5* and Elias Jabbour²

¹Division of Pharmacy and Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³University of California - Irvine, Orange, CA
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, Houston, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston

Paraskevi Diamanti, BSc, PhD^1*, William J Barendt, BSc^2*, Benjamin C Ede, BSc^2*, Charlotte V. Cox, BSc^3* and Allison Blair, PhD, BSc^2,3

¹NHS Blood and Transplant, Bristol Institute for Transfusion Sciences, Bristol, England
²School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom
³Bristol Institute for Transfusion Sciences, NHS Blood & Transplant, Bristol, United Kingdom

Viktoras Frismantas, MSc^1*, Maria Pamela Dobay, PhD^2*, Anna Rinaldi, PhD^1*, Kunz Joachim, MD^3*, Blerim Marovca^4*, Peter Horvath, PhD^5*, Mauro Delorenzi, PhD^2*, Gunnar Cario, MD^6*, Martin Schrappe, MD⁷, Martin Stanulla, MD^8*, Andreas E. Kulozik, MD, PhD⁹, Martina U. Muckenthaler, PhD¹⁰, Arend Stackelberg, MD^11*, Cornelia Eckert^11*, Thomas Radimerski, PhD^12*, Beat Bornhauser, PhD^13* and Jean-Pierre Bourquin, MD, PhD⁴

¹Department of Oncology, University Children’s Hospital, Zurich, Switzerland
²Swiss Institute of Bioinformatics, Lausanne, Switzerland
³Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Angelika Lautenschläger Children's Hospital, Heidelberg, Germany
⁴Department of Oncology, University Children’s Hospital Zurich, Zurich, Switzerland
⁵Synthetic and Systems Biology Unit, University of Szeged, Szeged, Hungary
⁶Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany
⁷Dept. of Pediatrics, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
⁸Department of Paediatric Haematology and Oncology, Hannover Medical School, Hannover, Germany
⁹Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany
¹⁰Department of Pediatric Oncology, Hematology, Immunology and Pulmunology, University of Heidelberg, Heidelberg, Germany
¹¹Department of Pediatric Oncology/Hematology, Charité Universitätsmedizin, Berlin, Germany
¹²Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland
¹³Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland

Kevin J. Curran, MD^1,2, Isabelle Riviere, PhD^2,3, Lewis B. Silverman, MD^4,5, Rachel Kobos, MD^1*, Neerav Shukla, MD^1*, Peter G Steinherz, MD¹, Farid Boulad, MD^1,2, Susan Prockop, MD¹, Andromachi Scaradavou, MD¹, Steven P. Margossian, MD, PhD^5,6, Xiuyan Wang, PhD^2*, Yongzeng Wang, PhD^2*, Victoria Szenes, NP^1*, Colleen H Dansereau, MSN, RN^5*, Brenda MacKinnon, RN^5*, Craig S. Sauter, MD⁷, Jae H. Park, MD⁸, Nancy A. Kernan, MD^1,2, Richard J O'Reilly, MD^1,2*, Michel Sadelain, MD, PhD^2,3 and Renier J. Brentjens, MD, PhD^2,8

¹Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
²Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA
⁵Division of Pediatric Hematology, Boston Children's Hospital, Boston, MA
⁶Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA
⁷Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY

Angela Maria Savino^1*, Jolanda Sarno^1*, Luca Trentin^2*, Margherita Vieri^1*, Grazia Fazio, PhD^1*, Michela Bardini^1*, Cristina Bugarin^3*, Gianluca Fossati^4*, Kara L. Davis, DO⁵, Giuseppe Gaipa, PhD³, Lueder Hinrich Meyer, MD^6*, Garry P. Nolan, Prof, PhD^7*, Andrea Biondi, Prof, MD⁸, Geertruy Te Kronnie, PhD^9*, Chiara Palmi, PhD^3* and Giovanni Cazzaniga¹

¹Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy
²2. Department of Women’s and Children’s Health, University of Padova, Padova, Italy
³Department of Pediatrics, Tettamanti Research Center, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy
⁴3. Preclinical R&D Department, Italfarmaco S.p.A., Cinisello Balsamo, Milano, Italy
⁵Pediatrics, Stanford University, Palo Alto, CA
⁶Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany
⁷Department of Microbiology and Immunology, Baxter Laboratory for Stem Cell Biology, Stanford University School of Medicine, Palo Alto, CA
⁸Centro Ricerca Tettamanti, Clinica Pediatrica, Università Milano Bicocca, Osp. San Gerardo/Fondazione MBBM, Monza (MB), Italy
⁹Department of Women’s and Children’s Health, University of Padova, Padova, Italy