-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

321. Blood Coagulation and Fibrinolytic Factors: Poster III

Blood Coagulation and Fibrinolytic Factors Program: Oral and Poster Abstracts
Type: Poster
Monday, December 7, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Yumiko Sakurai, MSc1,2*, Elaissa T. Hardy, PhD1,2*, Byungwook Ahn, PhD1,2*, Shannon L. Meeks, MD3, W. Hunter Baldwin, BS4*, Shawn M Jobe, MD, PhD5 and Wilbur A Lam, MD, PhD1,2

1Department of Pediatrics, Aflac Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA
2Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA
3Aflac Cancer Center and Blood Disorders Service, Emory University, Atlanta, GA
4Aflac Cancer and Blood Disorders Center, Emory University/Children's Healthcare of Atlanta, Atlanta, GA
5Blood Center of Wisconsin, Milwaukee, WI

John H. Griffin, PhD, Jose A. Fernandez, MD, PhD, Ranjeet Kumar Sinha, PhD, MSc, Darlene J. Elias, MD* and Hiroshi Deguchi, MD, PhD*

The Scripps Research Institute, La Jolla, CA

Robert French1*, Nicholas Martin2*, Timothy C. Nichols, M.D.3, Glenn P Niemeyer4*, Clinton D. Lothrop, PhD, DVM4* and Valder R Arruda, MD, PhD5

1University of Pennsylvania, Philadelphia, PA
2Children's Hospital of Philadelphia, Philadelphia, PA
3Francis Owen Blood Research Lab, University of North Carolina, Chapel Hill, NC
4University of Alabama, Birmingham, AL
5Perelman School of Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA

Sharma Ruchika, MD1*, Amanda P Waller, PhD1*, Shipra Agrawal, PhD1*, Berend H Isermann, MD2, William E Smoyer, MD1*, Marvin T Nieman, PhD3 and Bryce A. Kerlin, MD1

1Center for Clinical and Translational Research, Nationwide Children's Research Institute, Columbus, OH
2Institute of Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke University Medical Center, Magdeburg, Germany
3Pharmacology, Case Western Reserve University, Cleveland, OH

Giulia Pavani, PhD1*, Lacramioara Ivanciu, PhD1,2, Katherine A. Stafford1* and Paris Margaritis, DPhil1,2

1The Children's Hospital of Philadelphia, Philadelphia, PA
2University of Pennsylvania, Philadelphia, PA

Brian Cooley, Ph.D1*, David M Mann, PhD2*, Dougald Monroe, Ph.D.1*, Feng-Chang Lin3*, Paul E. Monahan, MD4 and Darrel W. Stafford, PhD5

1Pathology, UNC Chapel Hill, Chapel Hill, NC
2President, Mann Bioconsulting, Gaitherburg, MD
3Biostatistics, UNC Chapel Hill, Chapel Hill
4Department of Pediatrics and Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
5Department of Biology, University of North Carolina, Chapel Hill, NC

Joerg Kahle, PhD1*, Aleksander Orlowski1*, Anja Schmidt, PhD1*, Kerstin Brettschneider1*, Thomas Klingebiel, MD1, John F Healey, BS2*, Ernest T Parker, BA3*, John (Pete) S Lollar, MD2, Marc Jacquemin, MD4*, Manuela Krause, MD5*, Andreas Tiede, MD, PhD6, Dirk Schwabe, MD1* and Christoph Königs, MD, PhD1*

1Department of Pediatrics, University Hospital Frankfurt, Frankfurt am Main, Germany
2Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University, Atlanta, GA
3Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
4Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
5Hemostasis, Deutsche Klinik für Diagnostik, Wiesbaden, Germany
6Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

Douglas Drager1*, Sue Patarroyo-White1*, Hoson Chao1*, Ayman Ismail, PhD2*, Jiayun Liu1*, Amy M Holthaus, BS, MS2*, Ekta Chhabra1*, John Kulman, PhD2*, Volker Schellenberger, PhD3*, Tongyao Liu4* and Robert Peters, PhD2

1Biogen Inc, Cambridge, MA
2Hematology Research, Biogen, Cambridge, MA
3Amunix Operating Inc., Mountain View, CA
4Hematology Research, Biogen Idec, Cambridge, MA

Carlos Hipolito Villa, MD, PhD1*, Colin F Greineder, MD PhD2*, Ian Johnston, BS3, Daniel Pan, PhD2*, Ronald Carnemolla, PhD2*, Douglas B. Cines, MD4, Mortimer Poncz, MD5, Don L. Siegel, M.D., Ph.D.,4 and Vladimir R Muzykantov, MD PhD2*

1Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
2Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA
3Children's Hospital of Philadelphia, Philadelphia, PA
4Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
5Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA

Saulius Butenas, PhD*, Shannon M Prior, BS* and Kenneth G. Mann, PhD

Department of Biochemistry, University of Vermont, Colchester, VT

Robert Pachlinger1*, Rudolf Hartmann1*, Andrea Kolm1*, Erwin Panholzer1*, Nadja Ullrich1*, Fabian Knofl1*, Maria Schuster1*, Werner Hoellriegl, DVM1*, Friedrich Scheiflinger, PhD2 and Michael Dockal1*

1Baxalta Innovations GmbH, Vienna, Austria
2Research & Innovation, Baxalta Innovations GmbH, Vienna, Austria

Pedro Paz*, Jinger Xie* and Fred Aswad*

Global Biologics Research, Lead Discovery, Bayer HealthCare, San Francisco, CA

Qingyun Wang1*, Liang Tang, Ph.D.2*, Bei Hu3*, Yu Hu4* and Han Liu5,6

1Institute of Hematology,Union Hospital,, Huazhong University of Science & Technology (HUST), Wuhan, China
2Institute of Hematology, Union hospital,Tongji medical college,Huazhong University of science & technology, Wuhan, China
3Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
4Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China
5Division of Molecular Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO
6State Key Laboratory of Medical Genomics, Shanghai, China

Brandon M. Hardesty, MD1, Stacy Plum, PhD2*, Karen Thibaudeau, PhD2*, Martin Lee, PhD3* and Amy D. Shapiro, MD1

1Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
2ProMetic BioTherapeutics, Inc., Rockville, MD
3School of Public Health, University of California, Los Angeles, Los Angeles, CA

Eric F. Grabowski, MD, ScD1, Bohan Liu, BA2*, Matthew Gerace, BA2*, Paul E. Grabowski, Ph.D.3*, Peter Gunnarsson, Ph.D.4* and Mirella Ezban, Ph.D.4*

1Pediatric Hematology/Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
2Massachusetts General Hospital/Harvard Medical School, Boston, MA
3University of California, Irvine, Irvine, CA
4Novo Nordisk, Maaloev, Denmark

Yifan Xu1*, Maria Koellenberger2*, Volker Laux2*, Katalin Kauser1* and Derek Sim, PhD1*

1Bayer HealthCare LLC, US Innovation Center, San Francisco, CA
2Bayer Pharma AG, Wuppertal, Germany

Miguel Antonio Escobar, MD1, Daniel Preston Bond, BS2*, Madeline Cantini, RN3* and Krishna Cannon, RN3*

1Internal Medicine & Pediatrics. Hematology, University of Texas Health Science Center, Houston, TX
2Dan Bond and Associates, Galveston, TX
3Gulf States Hemophilia and Thrombophilia Center, University of Texas Health Science Center, Houston, TX

Satyaprakash Nayak, PhD1*, Dooyoung Lee, PhD2*, Steven Arkin, MD3, Steven W. Martin, PhD1*, Anne C. Heatherington, PhD2*, William S. Denney, PhD4*, Paolo Vicini, PhD5* and Fei Hua, PhD2*

1Pharmacometrics, Global Innovative Pharma - Clinical Pharmacology, Pfizer Inc., Cambridge, MA
2PharmaTherapeutics Clinical Research, Pfizer Inc., Cambridge, MA
3Rare Diseases Research Unit, Pfizer Inc., Cambridge, MA
4BioTherapeutics Clinical Research, Pfizer Inc., Cambridge, MA
5Pharmacokinetics, Dynamics and Metabolism – New Biological Entities, Pfizer Inc, San Diego, CA

Koji Yada, MD, PhD1*, Keiji Nogami, MD. PhD1*, Yasuaki Shida, MD, PhD1*, Masahiro Takeyama, MD, PhD1*, Ryu Kasai, MSc2* and Midori Shima, MD, PhD1

1Department of Pediatrics, Nara Medical University, Kashihara, Japan
2Chugai Pharmaceutical Co., Ltd., Tokyo, Japan

Shinpei Arai, MS1*, Saki Mukai, BA2*, Yuka Takezawa, PhD3*, Mitsutoshi Sugano, PhD3*, Takayuki Honda, MD, PhD1*, Fumihiro Ishida, MD, PhD4 and Nobuo Okumura, PhD4*

1Department of Laboratory Medicine, Graduate School of Medicine, Shinshu University, Matsumoto, Japan
2Department of Health and Medical Sciences, Graduate School of Medicine, Shinshu University, Matsumoto, Japan
3Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan
4Department of Biomedical Laboratory Sciences, Shinshu University, Matsumoto, Japan

Jingdi Liu1*, Liang Tang, Ph.D.2*, Wei Zeng, Ph.D.2*, Yu Hu1* and Han Liu, PhD3

1Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China
2Institute of Hematology, Union hospital,Tongji medical college,Huazhong University of science & technology, Wuhan, China
3State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine,, Shanghai, China

Jaroslaw Cwikla1*, Pawel Laguna, MD2,3*, Piotr Zbikowski4*, Pawel Olejnik5*, Klukowska Anna6*, Katarzyna Pawelec, MD, PhD7 and Michal Matysiak, Prof., MD PhD8*

1Department of Radiology;, University of Varmia and Masuria Olsztyn Poland,, Olsztyn, Poland
2Pediatric Hematology and Oncology, University, Warsaw, Poland
3Children's Hospital In Warsaw, Warsaw, Poland
4Department of Orthopedics, Ministry of Internal Affairs and Administration, Warsaw, Poland
5Department of Radiology, Institute of Cardiology, Warsaw, Poland
6Ped. Hematology and Oncology, Medical, Warsaw, Poland
7Department of Pediatrics, Hematology and Oncology, Medical University of Warsaw, Warsaw, Poland
8Department of Pediatrics, Hematology and Oncology, Medical University of Warsaw, Warsaw, Poland

Devi Gunasekera, MBBS1*, Kenneth B. Lewis, Ph.D.2*, Alexis A. Thompson, MD3, Ronald R, Louie, MD4, David W. Scott, PhD1 and Kathleen P. Pratt, Ph.D.1

1Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
2Bloodworks, NW, Seattle, WA
3Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
4University of Washington, Seattle, WA, Mary Bridge Children's Hospital, Tacoma, WA

Maricel G. Miguelino, MD1,2*, Priyadarsini Kumar, Ph.D.2*, Christopher Pivetti, M.Sc.2*, Lee Lanford, M.A.2*, Jerry S. Powell, MD1 and Aijun Wang, PhD2*

1Department of Internal Medicine, University of California, Davis, Sacramento, CA
2Department of Surgery, University of California, Davis, Sacramento, CA

Jerry A Grandoni, PhD

LFB USA, Framingham, MA

*signifies non-member of ASH