Reheman Adili, M.D^1*, Theodore R Holman, Ph.D^2* and Michael Holinstat, Ph.D³

¹Department of Pharmacology, University Of Michigan, Ann Arbor, MI
²Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA
³Department of Pharmacology, University of Michigan, Ann Arbor, MI

Wei Wang, MD^1*, Yang Tang, MD^1*, Ying Wang, MD, PhD^1*, Joanna Balcerek, PhD^2*, Wei Tong, PhD^2,3, Ross L. Levine, MD^4,5, Carrie Welch, PhD^1*, Alan Tall, MD^1* and Nan Wang, PhD^1*

¹Department of Medicine, Division of Molecular Medicine, Columbia University Medical Center, New York, NY
²Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA
³Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
⁴Memorial Sloan Kettering Cancer Center, New York, NY
⁵Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

Rustem I. Litvinov, PhD^1*, David H. Farrell, PhD², John W. Weisel, PhD¹ and Joel S. Bennett, MD³

¹Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA
²School of Medicine, L113, Oregon Health & Science Univ., Portland, OR
³Department of Medicine, Hematology-Oncology Division, University of Pennsylvania School of Medicine, Philadelphia, PA

Arnab Basu, MD, MPH^1*, Rohit Gosain, MD^2*, Udaya Tantry, PhD.^3*, Kenneth Miller, MD^4* and Paul A Gurbel, MD^5*

¹Internal Medicine Residency Program, Johns Hopkins University/ Sinai Hospital of Baltimore, Baltimore
²Sinai Hospital of Baltimore, Baltimore
³Sinai Center for Thrombosis Research, Sinai Hospital of Baltimore, Baltimore, MD
⁴Sinai Hospital of Baltimore, Baltimore, MD
⁵Sinai Center for Thrombosis Research, Sinai Hospital, Baltimore, MD

Benjamin Tourdot, PhD^1*, Paul F. Bray, MD², Leonard C. Edelstein, PhD³ and Michael Holinstat, PhD, FAHA^1,4

¹Department of Pharmacology, University of Michigan, Ann Arbor, MI
²The Cardeza Foundation for Hematologic Research and the Department of Medicine, Thomas Jefferson University, Jefferson Medical College, Philadelphia, PA
³Cardeza Foundation for Hematologic Research and Department of Medicine, Thomas Jefferson University, Philadelphia, PA
⁴Department of Internal Medicine, University of Michigan, Ann Arbor, MI

Dharmesh Gopalakrishnan, MD^1*, Heesun J Rogers, MD, PhD^2*, Paul Elson, PhD^3* and Keith R. McCrae, MD⁴

¹Department of Medicine, Cleveland Clinic, Cleveland, OH
²Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH
³Cleveland Clinic, Quantitative Health Sciences, Cleveland, OH
⁴Taussig Cancer Institute and Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH

Elena E. Solomou, MD, PhD, Vasilios Gizas, MD^*, Theodora Babali, MD^*, Angelos Perperis, MD^*, Evgenia Verigou, MD, PhD^*, Periklis Ntavlouros, MD, PhD^*, Charalambos Gogos, MD, PhD^* and Dimitrios Alexopoulos, MD, PhD^*

University of Patras Medical School, Dept of Internal Medicine, Patras, Greece