57th ASH Annual Meeting and Exposition (December 5-8, 2015): 901. Health Services and Outcomes Research – Non-Malignant Conditions: Health Outcomes in Sickle Cell Disease

Health Services and Outcomes Research – Non-Malignant Conditions Oral and Poster Abstracts
Oral

Tangerine 1 (WF1), Level 2 (Orange County Convention Center)

Moderators:

Timothy L. Mccavit, MD, University of Texas Southwestern Medical Center and Robert J. Klaassen, MD, Children's Hospital of Eastern Ontario

Disclosures:

No relevant conflicts of interest to declare.

7:00 AM

523

Lower Continuous Infusion, Higher Bolus Dose Patient-Controlled Analgesia Results in Shorter Hospitalization in Children with Sickle Cell Vaso-Occlusive Pain Crisis

Tabetha Todd, PharmD¹^*, Jonica Huntman, PharmD²^*, Gianna W. Sparks³^* and Monica L. Hulbert, MD⁴

¹Methodist LeBonheur Healthcare, Germantown, TN
²St. Louis Children's Hospital, St. Louis, MO
³University of Chicago, Chicago, IL
⁴Division of Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, MO

7:15 AM

524

Genetic Testing for the Diagnosis of Hemoglobinopathies Has Very High Clinical Utility

Charles T. Quinn, MD, MS¹, Amber H Begtrup, PhD²^*, Mary C. Paniagua, MA³^*, Hatice Duzkale, MD, MPH, PhD²^* and Kejian Zhang, MD, MBA²^*

¹Division of Hematology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
³Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

7:30 AM

525

Higher Dose of Opioids in the Emergency Department and Earlier Initiation of Oral Opioids after Hospitalization Are Associated with Shorter Length of Stay in Children with Sickle Cell Disease Treated for Acute Pain

Amanda M Brandow, DO, MS¹, Mark Nimmer²^*, Timothy Simmons, MStat³^*, T Charles Casper, PhD³^*, Larry J Cook, PhD³^*, J. Paul Scott, MD⁴, Julie A. Panepinto, MD, MSPH⁵ and David C. Brousseau, MD, MS⁶

¹Pediatric Hematology/Oncology, Medical College of Wisconsin and Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI
²Medical College of Wisconsin, Milwaukee, WI
³University of Utah/Pediatric Emergency Care Applied Research Network Data Coordinating Center, Salt Lake City, UT
⁴Medical College of Wisconsin, Blood Research Institute, Children's Research Institute, Milwaukee, WI
⁵The Medical College of Wisconsin/Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI
⁶Medical College of Wisconsin/Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI

7:45 AM

526

Clinically Meaningful Interpretation of Quantitative Sensory Testing As a Measure of Pain Sensitivity in Patients with Sickle Cell Disease

Amanda M Brandow, DO, MS¹, Rebecca Farley²^* and Julie A. Panepinto, MD, MSPH³

¹Pediatric Hematology/Oncology, Medical College of Wisconsin and Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI
²Medical College of Wisconsin, Milwaukee, WI
³The Medical College of Wisconsin/Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI

8:00 AM

527

A Pilot Study of Parent Education Intervention Improves Early Childhood Development Among Toddlers with Sickle Cell Disease

Melanie E. Fields, MD, MSCI¹, Regina Abel, PhD²^*, Sara K. Vesely, PhD³, Catherine Hoyt Drazen, OTD²^* and Allison King, MD, MPH, PhD²

¹Division of Pediatric Hematology/Oncology, Washington University in St. Louis, St. Louis, MO
²Washington University School of Medicine, St. Louis, MO
³Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

8:15 AM

528

A Study of Predictors of Clinical Outcomes and Healthcare Utilization in Children with Sickle Cell Disease Undergoing Allogeneic Hematopoietic Cell Transplantation

Prakash Satwani, MD, MBBS¹^*, Ruta Brazauskas, PhD²^*, Staci D. Arnold, MD, MBA³, Naya He, PhD²^*, Yimei Li, PhD⁴^*, Richard Aplenc, MD, PhD⁵^*, Matt Hall, PhD⁶^*, Yoshiko Atsuta, MD, Ph.D^7,8^*, Jignesh D Dalal, MD⁹, Theresa Hahn, PhD¹⁰, ZheZhen Jin, PhD¹¹^*, Carmem Sales-Bonfim, MD, PhD¹²^*, Nandita Khera, MD¹³ and Wael Saber, MD, MS¹⁴

¹Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York, NY
²CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, WI
³Columbia University Medical Center, Morgan Stanley Children's Hospital of New York- Presbyterian, New York, NY
⁴Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA
⁵Children's Hospital of Philadelphia, Philadelphia, PA
⁶Children's Hospital Association, Overland Park, KS
⁷Japanese Data Center for Haematopoietic Cell Transplantation, Nagoya, Japan
⁸Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan
⁹Bone Marrow Transplantation, Pediatric Hematology/Oncology, The Children's Mercy Hospitals and Clincs, Kansas City, MO
¹⁰Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY
¹¹Columbia University Medical Center, New York, NY
¹²Federal University of Parana, Hospital de Clinicas- UFPR, Curitiba, Brazil
¹³Department of Hematology/Oncology, Mayo Clinic Arizona and Phoenix Children's Hospital, Phoenix, AZ
¹⁴CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI

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^*signifies non-member of ASH

901.O2.6 901. Health Services and Outcomes Research – Non-Malignant Conditions: Health Outcomes in Sickle Cell Disease