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617.O1.3 617. Acute Myeloid Leukemia: Biology, Cytogenetics and Molecular Markers in Diagnosis and Prognosis: Novel Genetic Lesions in AML – Insight from Genome Wide Characterization

Acute Myeloid Leukemia: Biology, Cytogenetics and Molecular Markers in Diagnosis and Prognosis Program: Oral and Poster Abstracts
Type: Oral
Sunday, December 6, 2015: 7:30 AM-9:00 AM
W110, Level 1 (Orange County Convention Center)
Moderators:
Verena I. Gaidzik, MD, University Hospital of Ulm and Thomas Pabst, MD, University Hospital Bern

Disclosures:
No relevant conflicts of interest to declare.
7:30 AM

Fabiana Ostronoff, MD1, Rhonda E. Ries, MA1*, Robert B. Gerbing, MA2*, Marco A Marra, PhD3, Ma Yussanne4*, William Long, PhD5*, Stuart Zong5*, Karen Mungall, PhD5*, Andrew Andrew4*, Daniela S. Gerhard, PhD6*, Malcolm A. Smith, MD, PhD7, Gesuwan Patee8*, Tanja M. Davidsen, PhD6*, Leandro C. Hermida6*, Jason E. Farrar, M.D.9, Jaime Guidry Auvil8*, Susana C. Raimondi, PhD10, Betsy A. Hirsch, PhD2*, E. Anders Kolb, MD11, Alan S. Gamis, MD, MPH12, Todd A. Alonzo, PhD13 and Soheil Meshinchi, MD, PhD1

1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
2Children's Oncology Group, Monrovia, CA
3Canada’s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
4Genome Sciences Center, British Columbia Cancer Agency, Vancouver, Canada
5Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
6Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
7Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
8National Cancer Institute, Bethesda
9Department of Pediatics/Hematology Oncology Section, University of Arkansas for Medical Sciences, Little Rock, AR
10Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
11Nemours Center for Cancer and Blood Disorders, Alfred I. duPont Hospital for Children, Wilmington, DE
12Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO
13Keck School of Medicine, University of Southern California, Los Angeles, CA

7:45 AM

Diana Chin1*, Matthew A. Kutny, MD2, Jonathan Grim, MD, PhD3*, Robert B. Gerbing, MA4*, Kristen Miller, BS1*, Jason E. Farrar, M.D.5, Jaime M. Guidry Auvil, PhD6*, Malcolm A. Smith, MD, PhD7, Daniela S. Gerhard, PhD6*, Tanja M. Davidsen, PhD6*, Patee Gesuwan6*, Leandro C. Hermida6*, Marco A Marra, PhD8, Andrew J. Mungall, PhD9, Richard Moore, PhD8*, William Long, PhD9*, Yussanne Ma, PhD9*, Stuart Zong9*, E. Anders Kolb, MD10, Alan S. Gamis, MD, MPH11, Todd A. Alonzo, PhD12 and Soheil Meshinchi, MD, PhD1

1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
2Department of Pediatrics, Division of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
3VA Puget Sound Health Care Systems, Seattle, WA
4Children's Oncology Group, Monrovia, CA
5Department of Pediatics/Hematology Oncology Section, University of Arkansas for Medical Sciences, Little Rock, AR
6Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
7Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
8Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
9Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
10Nemours Center for Cancer and Blood Disorders, Alfred I. duPont Hospital for Children, Wilmington, DE
11Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO
12Keck School of Medicine, University of Southern California, Los Angeles, CA

8:00 AM

Jasmijn de Rooij, MD1*, Cristyn Branstetter, MD2, Jing Ma, PhD3*, Yongjin Li, PhD4*, Jinjun Cheng, MD, PhD3*, Cary Koss, BS2*, John Easton, PhD5*, Lonneke Jantine Verboon, BSc1*, Heather L. Mulder, BS5*, Michael Rusch, BA4*, Joshua Yew Suang Lim, BS6*, Katarina Reinhardt, PhD7*, Allen Eng Juh Yeoh, MD6, Lee-Yung Shih, MD8, Der-Cherng Liang, MD9, Stephanie Halene, MD10, Diane S Krause, MD, PhD11, Jinghui Zhang, PhD4*, James R. Downing, MD3, Franco Locatelli, MD, PhD12, Dirk Reinhardt, MD7, Marry M van den Heuvel-Eibrink, MD, PhD13,14*, Maarten Forenerod, PhD1*, C. Michel Zwaan, MD, PhD1,14 and Tanja A. Gruber, MD, PhD2,3

1Department of Pediatric Oncology, Erasmus MC-Sophia Children’s Hospital, Rotterdam, Netherlands
2Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN
3Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
4Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN
5Pediatric Cancer Genome Project, St. Jude Children's Research Hospital, Memphis, TN
6Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
7Department of Paediatric Oncology, University of Duisburg-Essen, Essen, Germany
8Department of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, College of Medicine Chang Gung University, Taipei, Taiwan
9Mackay Memorial Hospital, Taipei, Taiwan
10Section of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT
11Laboratory Medicine, Yale University School of Medicine, New Haven, CT
12University of Pavia, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy
13Department of Pediatric Oncology, Princess Maxima Center for Paediatric Oncology, Utrecht, Netherlands
14Dutch Childhood Oncology Group, Hague, Netherlands

8:15 AM

Oussama Abla, MD1, Raul C. Ribeiro, MD2, Anna Maria Testi, MD3*, Pau Montesinos Fernández, MD4*, Ursula Creutzig, MD5, Lillian Sung, MD, PhD6, Giancarlo Di Giuseppe, BSc1*, Derek Stephens, MSc1*, Henrik Hasle, MD, PhD7, Gertjan J.L. Kaspers, MD, PhD8, Luciano Dalla-Pozza, MB BS FRACP9, Alvaro Lassaletta, MD10*, Martin S. Tallman, MD11, Franco Locatelli, MD12, Dirk Reinhardt, MD13, Johann Hitzler, MD, FRCP (C), FAAP1 and Miguel A. Sanz, MD, PhD4

1Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
2St. Jude Children's Research Hospital, Memphis, TN
3Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Rome, Italy
4Department of Medicine, University of Valencia, Hospital Universitario y Politécnico La Fe, Valencia, Spain
5Pediatric Hematology/Oncology, Hannover Medical School, Hannover, Germany
6Population Health Sciences, Research Institute, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
7Department of Pediatrics, Aarhus University Hospital Skejby, Aarhus, Denmark
8Dutch Childhood Oncology Group, The Hague, Netherlands
9Department of Oncology, The Children's Hospital at Westmead, Westmead, Australia
10Pediatric Hematology-Oncology Department, Hospital Niño Jesús, Madrid, Spain
11Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY
12Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy
13AML-BFM Study Group, Pediatric Hematology/Oncology, University Children’s Hospital Essen, Essen, Germany

8:30 AM

Yi Zhou, MD, PhD1*, Daisuke Araki, MD2*, Megan Othus, PhD3*, Jerald P. Radich, MD4,5, Anna B. Halpern, MD6, Marco Mielcarek, MD4,7, Elihu H. Estey, MD4,8*, Brent L. Wood, MD, PhD1, Frederick R. Appelbaum, MD3,9 and Roland B. Walter, MD, PhD, MS4,10,11

1Department of Laboratory Medicine/Division of Hematopathology, University of Washington, Seattle, WA
2Department of Medicine, University of Washington, Seattle, WA
3Fred Hutchinson Cancer Research Center, Seattle, WA
4Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
5Department of Medicine/Division of Medical Oncology, University of Washington, Seattle, WA
6Hematology/Oncology Fellowship Program, University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA
7Department of Medicine/ Division of Medical Oncology, University of Washington, Seattle, WA
8Division of Hematology, University of Washington, Seattle, WA
9University of Washington, Seattle, WA
10Department of Medicine/Division of Hematology, University of Washington, Seattle, WA
11Department of Epidemiology, University of Washington, Seattle, WA

8:45 AM

Julia Elizabeth Maxson, PhD1, Rhonda Ries, MA1*, Yi-Cheng Wang, MS2*, Robert B. Gerbing, MA2*, E. Anders Kolb, MD3, Sarah L Thompson1*, Jaime M. Guidry Auvil, PhD4*, Marco A Marra, PhD5, Yussanne Ma, PhD6*, Stuart Zong6*, Andrew J. Mungall, PhD6, Richard Moore, PhD7*, William Long, PhD6*, Patee Gesuwan4*, Tanja M. Davidsen, PhD4*, Leandro C. Hermida4*, Jason E. Farrar, M.D.8, Jerald P. Radich, MD1, Malcolm A. Smith, MD, PhD9, Daniela S. Gerhard, PhD4*, Alan S. Gamis, MD, MPH2,10, Todd A. Alonzo, PhD2,11 and Soheil Meshinchi, MD, PhD1,2

1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
2Children's Oncology Group, Monrovia, CA
3Nemours Center for Cancer and Blood Disorders, Alfred I. duPont Hospital for Children, Wilmington, DE
4Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
5Canada’s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
6Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
7Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
8Department of Pediatics/Hematology Oncology Section, University of Arkansas for Medical Sciences, Little Rock, AR
9Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
10Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO
11Keck School of Medicine, University of Southern California, Los Angeles, CA

*signifies non-member of ASH