Lionel Ades, MD, PhD¹, Xavier Thomas, MD, PhD², Agnes Guerci-Bresler, MD^3*, Raffoux Emmanuel^4*, Olivier Spertini⁵, Norbert Vey⁶, Thierry Lamy, MD, PhD⁷, Christian Récher, MD PhD⁸, Arnaud Pigneux^9*, Dominique Bordessoule¹⁰, Eric Deconinck¹¹, Claude Gardin^12*, Olivier Tournilhac^13*, Jean-Francois Lambert, MD¹⁴, Patrice Chevallier, MD, PhD^15*, Stephane de Botton^16*, Julie Lejeune^17*, Hervé Dombret¹⁸, Sylvie Chevret^19* and Pierre Fenaux, MD, PhD²⁰

¹Service d’Hématologie Séniors, St Louis hospital, University Paris 7, Paris, France
²CHU, Lyon, France
³Hematology department, Hôpital d'Adultes du Brabois, CHU Nancy, Nancy, France
⁴Hematology Department, Saint Louis Hospital, Paris, France
⁵Hematology, CHUV, Lausanne, Switzerland
⁶Hematology, Institut Paoli-Calmettes, Marseille, France
⁷Haematology, CHU Pontchaillou, Rennes, France
⁸Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
⁹Hematology, Hôpital Haut Lêveque, Pessac, France
¹⁰Hematologie Clinique, CHU de Limoges, Limoges, France
¹¹Hematology, INSERM UMR1098 - CHU Jean Minjoz, Besancon, France
¹²Hematology, Hopital Avicenne, Bobigny, France
¹³CHU Clermont Ferrand, Clermont Ferrand Cedex 1, France
¹⁴Hospital of Nyon, Nyon, Switzerland
¹⁵Department of Hematology, Nantes University Hospital, Nantes, France
¹⁶Institut Gustave Roussy, Villejuif, France
¹⁷Hôpital Saint Louis, Assistance Publique - Hôpitaux de Paris, Paris, France
¹⁸Hematology, Hôpital Saint-Louis, Paris, France
¹⁹Biostatistics department, Hôpital Saint-Louis, Paris, France
²⁰Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France

Michael R. Savona, MD¹, Steven D. Gore, MD², Kathryn S. Kolibaba³, Stacey M. Ukrainskyj, BSN^4*, Keshava Kumar, PhD^4*, Qian Dong, MS^4*, Joel Hetzer, PhD^4*, Barry Skikne, MD⁴ and Guillermo Garcia-Manero, MD⁵

¹Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN
²Yale Cancer Center, New Haven, CT
³US Oncology Research, The Woodlands, TX
⁴Celgene Corporation, Summit, NJ
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Guillermo Garcia-Manero, MD¹, Ehab Atallah, MD², Samer K Khaled, MD³, Martha Arellano⁴, Mrinal M Patnaik, MBBS⁵, Todd A Butler^6*, Carla Ashby^6* and Bruno C. Medeiros, MD⁷

¹Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, Houston, TX
²Department of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
³City of Hope, Duarte, CA
⁴Hematology/Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
⁵Division of Hematology, Mayo Clinic, Rochester, MN
⁶MEI Pharma, Inc., San Diego, CA
⁷Division of Hematology/Oncology, Stanford Comprehensive Cancer Center, Stanford Univ., Stanford, CA

Amir T. Fathi, MD¹, Harry P. Erba, MD, PhD², Jeffrey E Lancet, M.D.³, Eytan M Stein, M.D.⁴, Roland B. Walter, MD, PhD, MS⁵, Daniel J. DeAngelo, MD, PhD⁶, Stefan Faderl, MD^7*, Anand P Jillella, MD⁸, Farhad Ravandi, MD⁹, Anjali S. Advani, MD¹⁰, Dale Bixby, MD, PhD¹¹, Tibor J. Kovacsovics, MD¹², Megan M. O'Meara, MD¹³, Dana A. Kennedy, PharmD¹⁴ and Anthony S. Stein, MD¹⁵

¹Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA
²Internal Medicine, Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
³Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
⁴Memorial Sloan Kettering Cancer Center, New York, NY
⁵Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁶Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁷John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
⁸Winship Cancer Institute of Emory University, Atlanta, GA
⁹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰Leukemia Program, Cleveland Clinic, Cleveland, OH
¹¹Univ. of Michigan Comprehensive Cancer Ctr., Ann Arbor, MI
¹²Huntsman Cancer Institute - University of Utah, Salt Lake City, UT
¹³Clinical Development, Seattle Genetics, Inc., Bothell, WA
¹⁴Clinical, Seattle Genetics, Inc., Bothell, WA
¹⁵Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA

Mei Guo^1*, Jianyong Li, MD, PhD², Zheng Dong^3*, Li Liu^4*, Xuliang Shen, MD^5*, Xinrong Zhan^6*, Depei Wu, MD^7*, Linhua Yang^8*, Yangyi Bao^9*, Xuzhang Lu^10*, Changlin Yu^11*, Jianhui Qiao^1*, Kaixun Hu^1*, Wanjun SUN^12*, Hongli Zuo^1*, Yajing Huang^1*, Junxiao Qiao^13*, Bo CAI^1*, Zhiqing LIU^1*, Tieqiang LIU^1*, Bo Yao^1*, Hongxia Zhao^12*, Juan WANG^14*, Qiyun SUN^1* and Huisheng Ai, MD^15*

¹Affiliated Hospital of Academy of Military Medical Sciences, BEIJING, China
²Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
³Affiliated Hospital of Academy of Military Medical Sciences, beijig, China
⁴Tangdu Hospital, Xian, China
⁵Heping Hospital of Changzhi Medical College, Changzhi, China
⁶Central Hospital of Xinxiang City, XINXIANG, China
⁷Department of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China
⁸The Second Hospital of Shanxi Medical University, Taiyuan, China
⁹The Third Affiliated Hospital of Anhui Medical University, hefei, China
¹⁰Changzhou No2 people's hospital, Changzhou, China
¹¹Affiliated Hospital of the Academy of Military Medical Sciences, Beijing, China
¹²Second Artillery General Hospital, BEIJING, China
¹³Second Artillery General Hospital, BEIJNG, China
¹⁴Central Hospital of Cangzhou City, CANGZHOU, China
¹⁵Department of Hematology and Transplantation, Affiliated Hospital of Academy of Military Medical Sciences, BEIJING, China

Eve Poret^1*, Chrystelle Vidal^2*, Yohan Desbrosses^3*, Fanny Angelot Delettre^1*, Maider Pagadoy^2*, Aurore Pugin^4*, Louis Benazet^2*, Franck Leroux^2*, Elise Robert^5*, Delphine Binda^2*, Sabeha Biichle^6*, Anne Roggy, PhD STUDENT^7*, Laure Philippe, medical student^8*, Berengere Gruson^9*, Anne-Claire Gac^10*, Michel Maigre^11*, Denis Caillot^12*, Remy Gressin, MD¹³, Pascal Turlure, MD^14*, Anne-Sophie Michallet, MD^15*, Lila Gilis^16*, Veronique Dorvaux^17*, Yazid Arkam^18*, Caroline Bonmati, MD^19*, Pierre Péterlin^20*, Pierre-Simon Rohrlich, MD, PhD^21*, Thorsten Braun, MD, PhD^22*, jean-Valere Malfuson^23*, Didier Bouscary, MD PhD^24*, Eric Pujade-Lauraine^25*, Felipe Suarez, MD, PhD²⁶, Carole Soussain, MD²⁷, Etienne Lengliné, MD^28*, Mathieu Puyade, md^29*, Tony Marchand, MD^30*, Denis Guyotat^31*, Bruno Lioure, MD^32*, Christian Recher, MD³³, Damien Roos-Weil^34*, Fabrice Jardin^35*, Jean-Pierre Marolleau³⁶, Bernard Drenou, MD^37*, Bernard Bonnotte, MD, PhD^38*, Sophie Dalac^39*, Philippe Saas, PhD⁴⁰, Francine Garnache Ottou, PhD^41* and Eric Deconinck⁴²

¹EFS BFC, INSERM UMR1098, Besançon cedex, France
²Inserm CIC1431, CHRU de Besançon, Besançon cedex, France
³CHU Jean Minjoz, Besançon, France
⁴CHRU de Besançon, Inserm CIC1431, Besançon cedex, France
⁵CHRU de Besançon, Besançon, France
⁶INSERM UMR 1098/Université Bourgogne Franche-Comté/EFS BFC, Besancon, France
⁷INSERM UMR 1098/Université Bourgogne Franche-Comté/ EFS BFC, Besançon cedex, France
⁸CHU Jean Minjoz, hematology, INSERM UMR 1098/Université Bourgogne Franche-Comté/ EFS BFC, Besançon, France
⁹Hopital d'Amiens, Amiens, France
¹⁰Hopital de Caen, Caen, France
¹¹Hopital de Chartres, Chartres, France
¹²Hôpital du Bocage, Dijon, France
¹³Service d'hématologie clinique, CHU Grenoble, Grenoble, France
¹⁴CHU de Limoges, Limoges, France
¹⁵CHU Lyon Sud-Pierre Bénite, Pierre-Benite, France
¹⁶Hopital Lyon Sud, Lyon, France
¹⁷Medecine Interne, Hopital Notre Dame de Bon Secours, Metz-Thionville, France
¹⁸Hopital de Mulhouse, Mulhouse, France
¹⁹CHU Nancy, Nancy, France
²⁰CHU Nantes, Nantes, France
²¹CHU de Nice, Nice, France
²²Clinical Hematology, CHU Avicenne, Bobigny, France
²³university hospital, clamart, France
²⁴CHU Cochin, Paris, France
²⁵Hospital Hotel Dieu, Paris, France
²⁶Hematologie, Hopital Necker, Assistance Publique-Hopitaux de Paris French Ref. Ctr. for Prima, Paris, France
²⁷Dept. of Hematologie, Centre René Huguenin, Saint-Cloud, France
²⁸Hospital Saint Louis, Paris, France
²⁹university hospital, poitiers, France
³⁰Department of Hematology, Centre Hospitalier Universitaire de Rennes, Rennes, France
³¹Hospital Saint Etienne, Saint Etienne, France
³²Department of Hematology and Oncology, CHU Hautepierre, Strasbourg, France
³³Hôpital Purpan-CHU de Toulouse, Toulouse, France
³⁴Hopital Pitie-Salpetriere, Paris, France
³⁵Centre Henri Becquerel, Rouen, France
³⁶Hematology, Hôpital Sud, Amiens, France
³⁷CH MULHOUSE, MULHOUSE, France
³⁸Department of Internal Medicine and Clinical Immunology, University Hospital, Dijon, France
³⁹Hospiatl Dijon, Dijon, France
⁴⁰EFS BFC, INSERM UMR 1098/Université Bourgogne Franche-Comté/ EFS BFC/LabEx lispSTIC, Besancon, France
⁴¹EFS BFC, Inserm UMR1098, University hospital Besancon, University Franche Comte, Besancon, France
⁴²Hematology, INSERM UMR1098 - CHU Jean Minjoz, Besancon, France