Program: Oral and Poster Abstracts
Session: 902. Health Services and Outcomes Research – Malignant Diseases: Poster II
A series of 9 online continuing medical education interventions targeting US-based hematologists/oncologists was developed to address specific education gaps identified by comprehensive needs assessment in MM (http://www.medscape.org/sites/advances/multiple-myeloma). To assess changes in knowledge and competence, a pre/post outcomes assessment was performed on a subset of 4 video or text-based activities whose focus included: management of transplant-eligible, transplant-ineligible, elderly patients, and differentiating between therapies. The outcomes survey method included knowledge- and case-based, multiple-choice questions focused on current evidence-based recommendations for the management of MM. The effect size (Cohen’s d) was calculated by comparing pre-assessment means and post-assessment means of linked learners to show effect of the educational interventions. Effect size of >0.8 and 0.4-0.8 are considered a large and medium effect size, respectively. A Chi square test was used to assess whether the mean pre-assessment score was different from the mean post-assessment score.
549 hematologist/oncologist who completed all pre- and post- assessment questions were evaluated. Statistically significant effect on gain in knowledge and competence was demonstrated in each of the 4 interventions (P < .05) with effect sizes of d = 0.4, 0.778, 0.966, and 1.408. Topics that demonstrated significant improvement in learning included: awareness of emerging data/trial design (23% mean increase, 95% CI: 10.4-35.6; P<.001), appropriately tailoring therapy for elderly patients with MM (37% mean increase, 95% CI: 17-57%; P<.001), and use of consolidation/maintenance therapy in MM (35% mean increase, 95% CI: 9.6-59.4%; P<.001). Despite improvements in learning, education gaps remain, as evidenced by the percent of incorrect answers post education, specifically in the areas of: understanding benefits of continuous lenalidomide plus dexamethasone (Rd) therapy (59% incorrect), evaluating clinical trial data for assessing tailored therapy for elderly patients with MM (43% incorrect), and key clinical considerations such as age, performance status, medical history, and comorbidities that could affect treatment of elderly patients with MM (36% incorrect).
Knowledge gaps permeate clinical practice specific to MM, with the potential to impact patient outcomes. This study demonstrated the success of a targeted online MM educational curriculum using video and text-based activities as evidenced by improvement in knowledge and competence relative to integrating new clinical trial data, tailoring MM therapy, and supportive care measures. The study also revealed additional areas requiring further education.
Disclosures: Van Laar: Medscape LLC: Employment . Landgren: Onyx: Research Funding ; International Myeloma Foundation: Research Funding ; Onyx: Honoraria ; Celgene: Honoraria ; Bristol-Myers Squibb: Honoraria ; Medscape: Honoraria ; BMJ Publishing: Honoraria ; Celgene: Consultancy ; BMJ Publishing: Consultancy ; Medscape: Consultancy ; Bristol-Myers Squibb: Consultancy ; Onyx: Consultancy .
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