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Late-Breaking Abstracts Session

Program: Late-breaking Abstracts
Tuesday, December 10, 2013: 7:30 AM-9:00 AM
Hall F (Ernest N. Morial Convention Center)

Klampfl Thorsten, Ph.D.1*, Heinz Gisslinger, MD2, Ashot S Harutyunyan, M.D.1*, Harini Nivarthi, Ph.D.1*, Elisa Rumi, MD3*, Jelena D. Milosevic, M.Sc.1*, Nicole C.C. Them, M.Sc.1*, Tiina Berg, B.Sc.1*, Bettina Gisslinger, MSc2*, Daniela Pietra, PhD3*, Doris Chen, Ph.D.1*, Gregory I. Vladimer, Ph.D.1*, Klaudia Bagienski, M.Sc.1*, Chiara Milanesi, BS3*, Ilaria Carola Casetti, MD3*, Emanuela Sant'Antonio, M.D.3*, Virginia Ferretti, PhD3*, Chiara Elena, MD4*, Fiorella Schischlik, M.Sc.1*, Ciara Cleary, M.Sc.1*, Melanie Six, B.Sc.1*, Martin Schalling, M.Sc.2*, Andreas Schönegger, M.Sc.1*, Christoph Bock, Ph.D.1*, Luca Malcovati, M.D.3,5*, Christiana Pascutto, Ph.D.3*, Giulio Superti-Furga, PhD1*, Mario Cazzola, MD3,5 and Robert Kralovics, Ph.D.1,2

1CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
2Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Vienna, Austria
3Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
4Department of Hematology Oncology, IRCCS Policlinico S. Matteo Foundation and University of Pavia, Pavia, Italy
5Department of Molecular Medicine, University of Pavia, Pavia, Italy

Jyoti Nangalia, MBBChir FRCPath1,2,3*, Charles E Massie, PhD1,3*, E Joanna Baxter, PhD3*, Francesca L Nice, MRes3*, Gunes Gundem, PhD1*, David Wedge, PhD1*, Edward Avezov, PhD4*, Juan Li, PhD3*, Karoline Kollmann, PhD3*, David G Kent, PhD3*, Athar Aziz, PhD3*, Anna L Godfrey, PhD FRCPath2,3*, Jonathan Hinton, MSc1*, Inigo Martincorena, PhD1*, Peter Van Loo, PhD1*, Amy V Jones, PhD5*, Paola Guglielmelli, PhD MD6*, Patrick Tarpey, PhD1*, Heather P Harding, PhD4*, John D Fitzpatrick, BA3*, Calum T Goudie, BA3*, Christina A Ortmann, MD3*, Stephen J Loughran, PhD3*, Keiran Raine, MSc1*, David Jones, MSc1*, Adam Butler, MSc1*, Jon W Teague, MSc1*, Sarah O'Meara1*, Stuart McLaren1*, Michele Bianchi2*, Yvonne Silber, MSc3*, Danai Dimitropolou, BSc3*, David Bloxham, MSc FRCPath2*, Laura J Mudie, BSc1*, Mark Maddison, BSc1*, Ben Robinson, BSc1*, Clodagh Keohane, MD7*, Cathy MacLean, MSc2*, Kate Hill, BM BS8*, Kim H. Orchard, PhD9, Sudhir Tauro, PhD10*, Ming-Qing Du, MB, PhD11, Mel Greaves, PhD, FRS12*, David Bowen, MD, PhD13, Brian Huntly, MBChB FRCPath PhD2,3*, Claire N Harrison, DM, FRCP, FRCPath7, Nicholas C.P. Cross, PhD, FRCPath5, David Ron, MD4*, Alessandro M. Vannucchi, MD14, Elli Papaemmanuil, PhD1*, Peter J. Campbell, PhD1,2* and Anthony R. Green, FRCPath, FMedSci2,3

1Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom
2Department of Haematology, Addenbrookes Hospital, Cambridge, United Kingdom
3Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom
4Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
5Faculty of Medicine, University of Southampton, Southampton, United Kingdom
6Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
7Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
8Department of Haematology, University Hospital Southampton, Southampton, United Kingdom
9University Hospital Southampton, Southampton, United Kingdom
10Dept of Haematology, Ninewells Hospital, Dundee, United Kingdom
11Dept. Pathology, Div. Histopathology, University of Cambridge, Cambridge, United Kingdom
12Haemato-Oncology Research Unit, Division of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom
13St. James's Institute of Oncology, Leeds, United Kingdom
14University of Florence, Florence, Italy

Bert A. Van der Reijden, PhD1, Davide Monteferrario, MS1*, Nikhita Bolar, MS2*, Anna Marneth, MS3*, Konnie Hebeda, MD, PhD1*, Saskia Bergevoet1*, Hans Veenstra1*, Britta Laros-van Gorkum, MD, PhD4*, Marius MacKenzie, MD, PhD1*, Cyrus Khandanpour, M.D.5, Lacramioara Botezatu, PhD6*, Erik Fransen, PhD2*, Guy Van Camp, PhD2*, Anthonie Duijnhouwer, MD1*, Simone Salemink, MS1*, Brigith Willemsen1*, Gerwin Huls, MD, PhD1*, Franks Preijers, PhD1*, Waander L. van Heerde, PhD1, Joop H. Jansen, PhD1, Marlies Kempers, MD, PhD1*, Bart Loeys, MD, PhD2* and Lut Van Laer, PhD2*

1Radboudumc, Nijmegen, Netherlands
2University of Antwerp, Antwerp, Belgium
3Nijmegen Centre for Molecular Life Sciences Laboratory of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
4Hematology, Radboud university medical center, Nijmegen, Netherlands
5University Hospital Essen, Essen, Germany
6Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Marc Righini, MD, MSc1*, Paul den Exter, MD2*, Josien van ES, MD3*, Franck Verschuren, MD4*, Alexandre Ghuisen, MD5*, Olivier Rutschman, MD6*, Thibault Schotté, MD7*, Olivier Sanchez, MD, PhD8*, Morgan Jaffrelot, MD9*, Meissa Karre, MD10*, Pascal Peudepiece, MD11*, Jeannot Schmidt, MD12*, Alessandra Principe, MD13*, Anja A van Houten, MD14*, Marije Ten Wolde, MD15*, Renée A Douma, MD16*, Germa Hazelaar, MD17*, Petra MG Erkens, PhD18*, Klaas Van Kralingen, MD19*, Marco Grootenboers, MD20*, Marc F Durian, MD21*, Whitney Cheung, MD22*, Henri Bounameaux, MD23*, Menno V. Huisman, MD, PhD24*, Pieter W. Kamphuisen, MD, PhD25 and Gregoire Le Gal, MD, PhD26*

1Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
2Amsterdam Medical center, Amsterdam, Netherlands
3Amsterdam Medical Center, Amsterdam, Netherlands
4Cliniques Universitaires St-Luc, Bruxelles, Belgium
5Liège University Hospital, Liège, Belgium
6Emergency Department, Geneva University Hospital, Geneva, Switzerland
7Centre Hospitalier Universitaire d'Angers, Angers, France
8Respiratory Unit, Georges Pompidou European Hospital, Paris, France
9Brest University Hospital, Brest, France
10Centre Hospitalier d'Agen, Agen, France
11Centre Hospitalier d'Argenteuil, Argenteuil, France
12Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France
13Centre Hospitalier de Morlaix, Morlaix, France
14Department of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands
15Almere Flevo Hospital, Almere, Netherlands
16Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
17Rijnstate Hospital, Arnhem, Netherlands
18Maastricht University, Maastricht, Netherlands
19Van Weel Bethesda Hospital, Dirksland, Netherlands
20Amphia Hospital, Breda, Netherlands
21Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
22Flevo Hospital, Almere, Netherlands
23Division of Angiology and Hemostasis, University Hospital of Geneva, Geneva 14, Switzerland
24Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, Netherlands
25Department of Vascular Medicine, University Medical Center Groningen, Groningen, Austria
26Medicine, Ottawa Health Research Institute, Ottawa, ON, Canada

Jan Krönke1*, Namrata D. Udeshi, PhD2*, Anupama Narla, MD3, Peter Grauman1*, Slater Hurst1*, Marie E. McConkey, PhD4*, Tanya Svinkina2*, Dirk Heckl1*, Eamon Comer5*, Xiaoyu Li5*, Christie Ciarlo5*, Emily Hartman5*, Monica Schenone5*, Stuart Schreiber5*, Steven A. Carr, PhD2* and Benjamin L. Ebert, MD PhD4*

1Brigham and Women's Hospital, Boston, MA
2Broad Institute of MIT and Harvard, Cambridge, MA
3Department of Pediatrics, Stanford University School of Medicine, Stanford, CA
4Division of Hematology, Brigham and Women's Hospital, Boston, MA
5Broad Institute, Cambridge, MA

Richard R. Furman, MD1, Jeff P. Sharman, MD2, Steven Coutre, MD3, Bruce D. Cheson, MD4, John Pagel, MD, PhD5, Peter Hillmen, MBChB, PhD6, Jacqueline C. Barrientos, MD7, Andrew D. Zelenetz, MD, PhD8, Thomas J. Kipps, MD, PhD9, Ian Flinn, MD, PhD10, Paolo Ghia, MD, PhD11, Herbert Eradat, MD12, Thomas Ervin, MD13*, Nicole Lamanna, MD14, Michael Hallek, MD15, Bertrand Coiffier, MD, PhD, Prof16, Andrew R. Pettitt, PhD, FRCPath17*, Shuo Ma, MD, PhD18, Stephan Stilgenbauer, MD19, Paula Cramer, MD20*, Maria Aiello21*, Dave M. Johnson21, Langdon L. Miller, MD21*, Daniel Li, PhD22*, Thomas M. Jahn, MD, PhD22, Roger D. Dansey, MD21* and Susan O'Brien23

1Weill Cornell Medical College, New York, NY
2US Oncology Research, Springfield, OR
3Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA
4Lombardi Comprehensive Cancer Center, Georgetown University Hospital, Washington, DC
5Fred Hutchinson Cancer Center, Seattle, WA
6St. James's University Hospital, Leeds, United Kingdom
7Department of Medicine, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY
8Memorial Sloan-Kettering Cancer Center, New York, NY
9Moores Cancer Center, University of California, San Diego, La Jolla, CA
10Sarah Cannon Research Institute, Nashville, TN
11IRCCS Ospedale and Università Vita-Salute San Raffaele, Milano, Italy
12David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA
13Florida Cancer Specialists, Englewood, FL
14Columbia University Medical Center, New York, NY
15University of Cologne, Cologne, Germany
16Hospices Civils de Lyon, University of Lyon, Pierre-Benite, France
17Royal Liverpool University Hospital, Liverpool, United Kingdom
18Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL
19University of Ulm, Ulm, Germany
20Department I of Internal Medicine and Center of Integrated Oncology Cologne Bonn, University Hospital, Cologne, Germany
21Gilead Sciences, Inc., Foster City, CA
22Gilead Sciences, Foster City, CA
23University of Texas MD Anderson Cancer Center, Houston, TX