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-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant

601.P1.16 601. Chromosomal Rearrangements and DNA Repair: Poster I

Program: Oral and Poster Abstracts
Type: Poster
Saturday, December 10, 2011: 5:30 PM-7:30 PM
Hall GH (San Diego Convention Center)
Sub-Clonal Genetic Heterogeneity in BCR-ABL1 Positive Acute Lymphoblastic Leukaemia

Maria-Jose Carnicer, PhD*, Frederik W van Delft, MD, PhD*, Lyndal Kearney, PhD and Mel Greaves, FRS

Division of Molecular Pathology, The Institute of Cancer Research, Sutton, United Kingdom

T(X;14)(p11.4;q32.33) Is Recurrent In Marginal Zone Lymphoma and Upregulates GPR34

Iwona Wlodarska, PhD1, Julio Finalet Ferreiro, M Sc1*, Thomas Tousseyn, MD PhD2*, Helena Urbankova, PhD1*, Lucienne Michaux, MD PhD1*, Laurence de Leval, MD PhD3*, Daan Dierickx, MD4*, Pascal Wolter, MD PhD5*, Xavier Sagaert, MD PhD6*, Peter Vandenberghe, MD, PhD7, Christiane De Wolf-Peeters, MD PhD8* and Mathijs Baens, PhD1,9*

1Center for Human Genetics, K.U.Leuven, Leuven, Belgium
2Department of Pathology, K.U.Leuven, Leuven, Belgium
3Department of Pathology, CHU Sart tilman, Liège, Belgium
4Department of Hematology, K.U.Leuven, Leuven, Belgium
5Department of General Medical Oncology, K.U.Leuven, Leuven, Belgium
6Morphology and Molecular Pathology, K.U.Leuven, Leuven, Belgium
7Center for Human Genetics, Katholieke Universiteit Leuven, Leuven, Belgium
8Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium
9Department of Molecular and Developmental Genetics, Flanders Institute for Biotechnology (VIB), Leuven, Belgium

Lig4 R278H Mutation Impacts on LT-HSC Functions, Cancer Development and Aging

Catherine T. Yan1, Ji hye Park2*, Parames Muniandy1*, Logan Troppito1* and Robert Welner3*

1Pathology, BIDMC, Harvard Medical School, Boston, MA
2Pathology, BIDMC, Boston, MA
3BIDMC, Boston, MA

What Is New? An Update of the MLL Recombinome Including the Three Novel Partner Genes ABI2, PDS5A, and TOP3A

Claus Meyer, PhD1*, Mariana Emerenciano, PhD2*, Eva A Coenen, MD3*, Eric Delabesse, MD, PhD4*, Charles Herbaux, MD5*, Julia Hofmann1*, Marry M. van den Heuvel-Eibrink, MD, PhD3, C. Michel Zwaan, MD, PhD3, Theo Dingermann, PhD1*, Tae Sung Park, MD, PhD6*, Thomas Klingebiel, MD7* and Rolf Marschalek, PhD1*

1Institute of Pharmaceutical Biology, ZAFES, Diagnostic Center of Acute Leukemias (DCAL), Goethe-University of Frankfurt, Frankfurt am Main, Germany
2Pediatric Hematology-Oncology Program, Research Center, Instituto Nacional de Câncer, Rio de Janeiro
3Pediatric Oncology/Hematology, ErasmusMC/ Sophia Children's Hospital, Rotterdam, Netherlands
4Laboratory for Hematology and molecular biology, Hôpital Purpan, Toulouse, France
5Hematology, CHU de LILLE, Lille, France
6Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul , South Korea
7Johann Wolfgang Goethe University, Frankfurt, Germany

Granulocyte Colony-Stimulating Factor Induced Proliferation Leads to An Increase in Radical Oxygen Species Production and DNA Damage in Hematopoietic Stem Cells

Liliana Souza, PhD1*, Erica Silva, PhD1*, Elissa Calloway, MS1*, Michael Rossi, PhD2* and Morgan L. McLemore, MD3

1Hematology/Oncology, Winship Cancer Institute, Atlanta, GA
2Department of Radiology Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
3Winship Cancer Institute-Hematology and Medical Oncology, Emory University Sch. of Med., Atlanta, GA

*signifies non-member of ASH